Communications Biology最新文献_第6页

Vibrational noise disrupts Nezara viridula communication, irrespective of spectral overlap. 无论频谱重叠与否，振动噪声都会干扰 Nezara viridula 的通信。

IF 5.2 1区生物学

Communications Biology Pub Date : 2024-11-19 DOI: 10.1038/s42003-024-07185-3

Rok Janža, Nataša Stritih-Peljhan, Aleš Škorjanc, Jernej Polajnar, Meta Virant-Doberlet

{"title":"Vibrational noise disrupts Nezara viridula communication, irrespective of spectral overlap.","authors":"Rok Janža, Nataša Stritih-Peljhan, Aleš Škorjanc, Jernej Polajnar, Meta Virant-Doberlet","doi":"10.1038/s42003-024-07185-3","DOIUrl":"10.1038/s42003-024-07185-3","url":null,"abstract":"Insects rely on substrate vibrations in numerous intra- and interspecific interactions. Yet, our knowledge of noise impact in this modality lags behind that in audition, limiting our understanding of how anthropogenic noise affects insect communities. Auditory research has linked impaired signal perception in noise (i.e., masking) to spectral overlap. We investigated the impact of noise with different spectral compositions on the vibrational communication of the stink bug Nezara viridula, examining courtship behaviour and signal representation by sensory neurons. We found negative effects of vibrational noise regardless of spectral overlap, challenging common expectations. Noise impaired the ability of males to recognize the female signal and localise its source: overlapping noise decreased sensitivity of receptor neurons to the signal and disrupted signal frequency encoding by phase-locking units, while non-overlapping noise only affected frequency encoding. Modelling neuronal spike triggering in sensory neurons linked disrupted frequency encoding to interference-induced alterations of the signal waveform. These alterations also affected time delays between signal arrivals to different legs, crucial for localisation. Our study thus unveils a new masking mechanism, potentially unique to insect vibrosensory systems. The findings highlight the higher vulnerability of vibration-mediated behaviour to noise, with implications for insect interactions in natural and anthropogenically altered environments.","PeriodicalId":10552,"journal":{"name":"Communications Biology","volume":"7 1","pages":"1533"},"PeriodicalIF":5.2,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11577028/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ecological interactions between marine RNA viruses and planktonic copepods. 海洋 RNA 病毒与浮游桡足类之间的生态互动。

IF 5.2 1区生物学

Communications Biology Pub Date : 2024-11-19 DOI: 10.1038/s42003-024-07189-z

Junya Hirai, Seiji Katakura, Hiromi Kasai, Satoshi Nagai

{"title":"Ecological interactions between marine RNA viruses and planktonic copepods.","authors":"Junya Hirai, Seiji Katakura, Hiromi Kasai, Satoshi Nagai","doi":"10.1038/s42003-024-07189-z","DOIUrl":"10.1038/s42003-024-07189-z","url":null,"abstract":"The interactions between zooplankton and viruses, which have been overlooked despite their crucial roles in marine ecosystems, are investigated in the copepod Pseudocalanus newmani. Copepod transcriptome data reveal four novel RNA viruses and weekly zooplankton samplings detect all viruses with different prevalence peaks during low-abundance periods of P. newmani. In addition to water temperature and food quality, our results suggest that marine virus is one of the factors controlling copepod population dynamics. Gene expression analysis indicates possible increased viral replication and decreased copepod movement in P. newmani with the Picorna-like virus, which is closely related to phytoplankton viruses, and metabarcoding diet analysis detects diatoms as P. newmani's major prey. Viral-like particles are observed in the gut contents of copepods during the high prevalence of this virus, suggesting infected copepod prey may affect copepod physiology. These results show that investigating zooplankton-virus interactions can provide a better understanding of marine ecosystems.","PeriodicalId":10552,"journal":{"name":"Communications Biology","volume":"7 1","pages":"1507"},"PeriodicalIF":5.2,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11577009/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dietary phytosterols induce infertility in female mice via epigenomic modulations. 膳食植物甾醇通过表观基因组调控诱导雌性小鼠不孕。

IF 5.2 1区生物学

Communications Biology Pub Date : 2024-11-19 DOI: 10.1038/s42003-024-07233-y

Yoshihide Yamanashi, Toko Komine, Yasushi Hirota, Hiroshi Suzuki, Yutaka Osuga, Tappei Takada

{"title":"Dietary phytosterols induce infertility in female mice via epigenomic modulations.","authors":"Yoshihide Yamanashi, Toko Komine, Yasushi Hirota, Hiroshi Suzuki, Yutaka Osuga, Tappei Takada","doi":"10.1038/s42003-024-07233-y","DOIUrl":"10.1038/s42003-024-07233-y","url":null,"abstract":"Dietary modifications to overcome infertility have attracted attention; however, scientifically substantiated information on specific dietary components affecting fertility and their mechanisms is limited. Herein, we investigated diet-induced, reversible infertility in female mice lacking the heterodimer of ATP-binding cassette transporters G5 and G8 (ABCG5/G8), which functions as a lipid exporter in the intestine. We found that dietary phytosterols, especially β-sitosterol and brassicasterol, which are substrates of ABCG5/G8, have potent but reversible reproductive toxicities in mice. Mechanistically, these phytosterols inhibited ovarian folliculogenesis and reduced egg quality by enhancing polycomb repressive complex 2-mediated histone H3 trimethylation at lysine 27 in the ovary. Clinical analyses showed that serum phytosterol levels were significantly and negatively correlated with the blastocyst development rate of fertilized eggs in women undergoing in vitro fertilization, suggesting that phytosterols affect egg quality in both humans and mice. Thus, avoiding excessive intake of certain phytosterols would be beneficial for female reproductive health.","PeriodicalId":10552,"journal":{"name":"Communications Biology","volume":"7 1","pages":"1535"},"PeriodicalIF":5.2,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11577050/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

From the brain's encoding of input dynamics to its behavior: neural dynamics shape bias in decision making. 从大脑对输入动态的编码到其行为：神经动态塑造决策偏差。

IF 5.2 1区生物学

Communications Biology Pub Date : 2024-11-19 DOI: 10.1038/s42003-024-07235-w

Angelika Wolman, Stephan Lechner, Lorenzo Lucherini Angeletti, Josh Goheen, Georg Northoff

{"title":"From the brain's encoding of input dynamics to its behavior: neural dynamics shape bias in decision making.","authors":"Angelika Wolman, Stephan Lechner, Lorenzo Lucherini Angeletti, Josh Goheen, Georg Northoff","doi":"10.1038/s42003-024-07235-w","DOIUrl":"10.1038/s42003-024-07235-w","url":null,"abstract":"The human brain is tightly connected to the individual's environment and its input dynamics. How the dynamics of periodic environmental stimuli influence neural activity and subsequent behavior via neural entrainment or alignment is not fully clear yet, though. This study explores how periodic environmental stimuli influence neural activity and behavior. EEG data was collected during a Go-NoGo task with a periodic intertrial interval (ITI) of 1.3 s (0.769 Hz). Results showed that the task's temporal structure increased power spectrum activity at 0.769 Hz, which showed high intersubject variability. Higher task-periodicity effects were linked to stronger phase-based intertrial coherence (ITC) and reduced neural complexity, as measured by lower Lempel-Ziv Complexity (LZC). Additionally, higher periodicity in the power spectrum correlated with faster reaction times and stronger response bias. We conclude that the encoding of the inputs' dynamics into the brains power spectrum shapes subsequent behavior, e.g., RT and response bias, through reducing neural complexity.","PeriodicalId":10552,"journal":{"name":"Communications Biology","volume":"7 1","pages":"1538"},"PeriodicalIF":5.2,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11576847/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bilayered skin equivalent mimicking psoriasis as predictive tool for preclinical treatment studies. 模拟银屑病的双层皮肤等效物作为临床前治疗研究的预测工具。

IF 5.2 1区生物学

Communications Biology Pub Date : 2024-11-18 DOI: 10.1038/s42003-024-07226-x

Bianka Morgner, Oliver Werz, Cornelia Wiegand, Jörg Tittelbach

{"title":"Bilayered skin equivalent mimicking psoriasis as predictive tool for preclinical treatment studies.","authors":"Bianka Morgner, Oliver Werz, Cornelia Wiegand, Jörg Tittelbach","doi":"10.1038/s42003-024-07226-x","DOIUrl":"10.1038/s42003-024-07226-x","url":null,"abstract":"Psoriasis is a prevalent, inflammatory skin disease without cure. Further research is required to unravel dysregulated processes and develop new therapeutic interventions. The lack of suitable in vivo and in vitro preclinical models is an impediment in the psoriasis research. Recently, the development of 3D skin models has progressed including replicas with disease-like features. To investigate the use of in vitro models as preclinical test tools, the study focused on treatment responses of 3D skin replicas. Cytokine-priming of skin organoids induced psoriatic features like inflammation, antimicrobial peptides (AMP), hyperproliferation and impaired differentiation. Topical application of dexamethasone (DEX) or celastrol (CEL), a natural anti-inflammatory compound reduced the secretion of pro-inflammatory cytokines. DEX and CEL decreased the gene expression of inflammatory mediators. DEX barely affected the psoriatic AMP transcription but CEL downregulated psoriasis-driven AMP genes. Subcutaneous application of adalimumab (ADM) or bimekizumab (BMM) showed anti-psoriatic effects via protein induction of the differentiation marker keratin-10. Dual blockage of TNF-α and IL-17A repressed the inflammatory psoriasis phenotype. BMM inhibited the psoriatic expression of AMP genes and induced KRT10 and cell-cell contact genes. The present in vitro model provides a 3D environment with in vivo-like cutaneous responses and represents a promising tool for preclinical investigations.","PeriodicalId":10552,"journal":{"name":"Communications Biology","volume":"7 1","pages":"1529"},"PeriodicalIF":5.2,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11574237/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142666966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring human pancreatic organoid modelling through single-cell RNA sequencing analysis. 通过单细胞 RNA 测序分析探索人类胰腺器官模型。

IF 5.2 1区生物学

Communications Biology Pub Date : 2024-11-18 DOI: 10.1038/s42003-024-07193-3

Alessandro Cherubini, Francesco Rusconi, Roberta Piras, Kaja Nicole Wächtershäuser, Marta Dossena, Mario Barilani, Cecilia Mei, Lotta Hof, Valeria Sordi, Francesco Pampaloni, Vincenza Dolo, Lorenzo Piemonti, Lorenza Lazzari

{"title":"Exploring human pancreatic organoid modelling through single-cell RNA sequencing analysis.","authors":"Alessandro Cherubini, Francesco Rusconi, Roberta Piras, Kaja Nicole Wächtershäuser, Marta Dossena, Mario Barilani, Cecilia Mei, Lotta Hof, Valeria Sordi, Francesco Pampaloni, Vincenza Dolo, Lorenzo Piemonti, Lorenza Lazzari","doi":"10.1038/s42003-024-07193-3","DOIUrl":"10.1038/s42003-024-07193-3","url":null,"abstract":"Human organoids have been proposed to be powerful tools mimicking the physiopathological processes of the organs of origin. Recently, human pancreatic organoids (hPOs) have gained increasing attention due to potential theragnostic and regenerative medicine applications. However, the cellular components of hPOs have not been defined precisely. In this work, we finely characterized these structures, focusing first on morphology and identity-defining molecular features under long-term culture conditions. Next, we focused our attention on hPOs cell type composition using single-cell RNA sequencing founding a complex heterogeneity in ductal components, ranging from progenitor components to terminally differentiated ducts. Furthermore, an extensive comparison of human pancreatic organoids with previously reported transcriptomics signature of human and mouse pancreatic ductal populations, confirmed the functional pancreatic duct subpopulation heterogeneity. Finally, we showed that pancreatic organoid cells follow a precise developmental trajectory and utilize diverse signalling mechanisms, including EGF and SPP1, to facilitate cell-cell communication and maturation. Together our results offer an in-depth description of human pancreatic organoids providing a strong foundation for future in vitro diagnostic and translational studies of pancreatic health and disease.","PeriodicalId":10552,"journal":{"name":"Communications Biology","volume":"7 1","pages":"1527"},"PeriodicalIF":5.2,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11574267/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142667112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Symbiodiniaceae algal symbionts of Pocillopora damicornis larvae provide more carbon to their coral host under elevated levels of acidification and temperature. 在酸化和温度升高的条件下，大棘鲷幼虫的共生藻类能为珊瑚宿主提供更多的碳。

IF 5.2 1区生物学

Communications Biology Pub Date : 2024-11-18 DOI: 10.1038/s42003-024-07203-4

Youfang Sun, Huaxia Sheng, Nils Rädecker, Yi Lan, Haoya Tong, Lintao Huang, Lei Jiang, Guillermo Diaz-Pulido, Bobo Zou, Yuyang Zhang, Shuh-Ji Kao, Pei-Yuan Qian, Hui Huang

{"title":"Symbiodiniaceae algal symbionts of Pocillopora damicornis larvae provide more carbon to their coral host under elevated levels of acidification and temperature.","authors":"Youfang Sun, Huaxia Sheng, Nils Rädecker, Yi Lan, Haoya Tong, Lintao Huang, Lei Jiang, Guillermo Diaz-Pulido, Bobo Zou, Yuyang Zhang, Shuh-Ji Kao, Pei-Yuan Qian, Hui Huang","doi":"10.1038/s42003-024-07203-4","DOIUrl":"10.1038/s42003-024-07203-4","url":null,"abstract":"Climate change destabilizes the symbiosis between corals and Symbiodiniaceae. The effects of ocean acidification and warming on critical aspects of coral survical such as symbiotic interactions (i.e., carbon and nitrogen assimilation and exchange) during the planula larval stage remain understudied. By combining physiological and stable isotope techniques, here we show that photosynthesis and carbon and nitrogen assimilation (H13CO3- and 15NH4+) in Pocillopora damicornis coral larvae is enhanced under acidification (1000 µatm) and elevated temperature (32 °C). Larvae maintain high survival and settlement rates under these treatment conditions with no observed decline in symbiont densities or signs of bleaching. Acidification and elevated temperature both enhance the net and gross photosynthesis of Symbiodiniaceae. This enhances light respiration and elevates C:N ratios within the holobiont. The increased carbon availability is primarily reflected in the 13C enrichment of the host, indicating a greater contribution of the algal symbionts to the host metabolism. We propose that this enhanced mutualistic symbiotic nutrient cycling may bolster coral larvae's resistance to future ocean conditions. This research broadens our understanding of the early life stages of corals by emphasizing the significance of symbiotic interactions beyond those of adult corals.","PeriodicalId":10552,"journal":{"name":"Communications Biology","volume":"7 1","pages":"1528"},"PeriodicalIF":5.2,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11573989/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142667150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cross-talk between tissues is critical for intergenerational acclimation to environmental change in Acanthochromis polyacanthus. 组织间的交叉对话对于多棘鲷对环境变化的代际适应至关重要。

IF 5.2 1区生物学

Communications Biology Pub Date : 2024-11-18 DOI: 10.1038/s42003-024-07241-y

Sneha Suresh, Megan J Welch, Philip L Munday, Timothy Ravasi, Celia Schunter

{"title":"Cross-talk between tissues is critical for intergenerational acclimation to environmental change in Acanthochromis polyacanthus.","authors":"Sneha Suresh, Megan J Welch, Philip L Munday, Timothy Ravasi, Celia Schunter","doi":"10.1038/s42003-024-07241-y","DOIUrl":"10.1038/s42003-024-07241-y","url":null,"abstract":"Organisms' responses to environmental changes involve complex, coordinated responses of multiple tissues and potential parental influences. Here using a multi-tissue approach we determine how variation in parental behavioural tolerance and exposure to elevated CO2 influences the developmental and intergenerational molecular responses of their offspring in the coral reef fish Acanthochromis polyacanthus to future ocean acidification (OA) conditions. Gills and liver showed the highest transcriptional response to OA in juvenile fish regardless of parental OA conditioning, while the brain and liver showed the greatest intergenerational acclimation signals. Developmentally induced signals of OA, such as altered neural function in the brain, were restored to control levels after intergenerational exposure. Intergenerational CO2 exposure also enabled the offspring to adjust their metabolic processes, potentially allowing them to better meet the energetic demands of a high CO2 environment. Furthermore, offspring of OA-exposed parents differentially expressed a new complement of genes, which may facilitate intergenerational acclimatory responses. A genetic component of intergenerational plasticity also played a crucial role, with the parental behavioural phenotype largely determining the offspring's transcriptional signals. Overall, our results reveal tissue-specific transcriptional changes underlying intergenerational plastic responses to elevated CO2 exposure, enhancing understanding of organismal acclimation to OA throughout the whole body.","PeriodicalId":10552,"journal":{"name":"Communications Biology","volume":"7 1","pages":"1531"},"PeriodicalIF":5.2,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11574262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142666985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

KDM2B regulates stroke injury by modulating OGT-mediated 0-GlcNAcylation of SLC7A11. KDM2B 通过调节 OGT 介导的 SLC7A11 的 0-GlcNAcylation 来调节中风损伤。

IF 5.2 1区生物学

Communications Biology Pub Date : 2024-11-18 DOI: 10.1038/s42003-024-07251-w

Yi Li, Liangbo Niu, Dai Zheng, Xinxing Zhang, Lu Feng, Jing Fu

引用次数: 0

Elucidating metabolic tuning of mixed purple phototrophic bacteria biofilms in photoheterotrophic conditions through microbial photo-electrosynthesis. 通过微生物光-电合成，阐明紫色混合光营养细菌生物膜在光异养条件下的代谢调整。

IF 5.2 1区生物学

Communications Biology Pub Date : 2024-11-18 DOI: 10.1038/s42003-024-07188-0

Sara Díaz-Rullo Edreira, Ioanna A Vasiliadou, Amanda Prado, Juan José Espada, Ruddy Wattiez, Baptiste Leroy, Fernando Martínez, Daniel Puyol

{"title":"Elucidating metabolic tuning of mixed purple phototrophic bacteria biofilms in photoheterotrophic conditions through microbial photo-electrosynthesis.","authors":"Sara Díaz-Rullo Edreira, Ioanna A Vasiliadou, Amanda Prado, Juan José Espada, Ruddy Wattiez, Baptiste Leroy, Fernando Martínez, Daniel Puyol","doi":"10.1038/s42003-024-07188-0","DOIUrl":"10.1038/s42003-024-07188-0","url":null,"abstract":"Reducing greenhouse gas emissions is critical for humanity nowadays, but it can be beneficial by developing engineered systems that valorize CO2 into commodities, thus mimicking nature's wisdom. Purple phototrophic bacteria (PPB) naturally accept CO2 into their metabolism as a primary redox sink system in photo-heterotrophy. Dedicated use of this feature for developing sustainable processes (e.g., through negative-emissions photo-bioelectrosynthesis) requires a deep knowledge of the inherent metabolic mechanisms. This work provides evidence of tuning the PPB metabolic mechanisms upon redox stressing through negative polarization (-0.4 and -0.8 V vs. Ag/AgCl) in photo-bioelectrochemical devices. A mixed PPB-culture upregulates its ability to capture CO2 from organics oxidation through the Calvin-Besson-Bassam cycle and anaplerotic pathways, and the redox imbalance is promoted to polyhydroxyalkanoates production. The ecological relationship of PPB with mutualist bacteria stabilizes the system and opens the door for future development of photo-bioelectrochemical devices focused on CO up-cycling.","PeriodicalId":10552,"journal":{"name":"Communications Biology","volume":"7 1","pages":"1526"},"PeriodicalIF":5.2,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11574181/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142667103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0