Complementary Medicine Research最新文献

{"title":"Global Trends and Collaborative Models in Manipulative Therapy for Low Back Pain: A Bibliometric and Academic Network Analysis.","authors":"Yukui Tian, Nianrong Han, Xue Bai, Junchang Liu","doi":"10.1159/000542978","DOIUrl":"10.1159/000542978","url":null,"abstract":"<p><strong>Background: </strong>Low back pain (LBP) is a prevalent condition that significantly affects work productivity and quality of life. Despite advancements in treatment, LBP continues to pose a global health challenge, with increasing research on manipulative therapy as a non-invasive treatment option. This study aimed to provide a comprehensive bibliometric analysis of global research trends in manipulative therapy for LBP.</p><p><strong>Summary: </strong>This study utilized the Web of Science Core Collection database to analyze global research dynamics on manipulative therapy for LBP from 1998 to 2023. A total of 2,879 articles were identified and analyzed using CiteSpace software, revealing key research trends, leading countries, and influential contributors. The analysis demonstrated that research on manipulative therapy for LBP has been steadily increasing, particularly between 2019 and 2021. The USA, the Netherlands, and Denmark were among the leading countries in this field. Core research concepts identified through keyword co-occurrence analysis include \"low back pain,\" \"manipulative therapy,\" and \"spinal manipulation.\"</p><p><strong>Key messages: </strong>Manipulative therapy for LBP is a growing field with increasing global interest, particularly between 2019 and 2021. The USA, Netherlands, and Denmark are leading contributors to the research, with notable academic collaborations. Future research should focus on comparative treatment effectiveness, safety assessments, and mechanistic analyses to further validate the role of manipulative therapy in LBP management.</p>","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"160-175"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143001479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Auricular Acupressure on Myopia Prevention among Children Aged 6-12 Years with Pre-Myopia in China: Study Protocol of a Prospective Multi-Center Randomized Controlled Trial.","authors":"Jianquan Wang, Yipeng Shi, Xin Yan, Xinru Wu, Ke'er Cao, Luquan Chen, Jun Liu, Hua Peng, Chunxia Li, Liqun Chu, Danlei Wu, Shangkun Zhou, Yingxin Yang, Yangzhong Wang, Xinquan Liu, Jike Song, Fengming Liang, Jing Yao, Zhihua Shen, Fengmei Zhang, Xiaolei Yao, Tao Zuo, Wei Shi, Wujun Li, Xinyue Hou, Zefeng Kang","doi":"10.1159/000542442","DOIUrl":"10.1159/000542442","url":null,"abstract":"<p><strong>Background: </strong>The increasing prevalence of myopia among Chinese children and adolescents, especially at younger ages, has emerged as a significant concern in recent years. Pre-myopia is a key period for myopia prevention and control in children and adolescents. Previous studies suggested auricular acupressure (AA) therapy might offer a viable approach to prevent and slow down myopia progression. Nonetheless, these studies lack robust, high-quality, large-scale, multi-center evidence to conclusively support such assertions. The purpose of this research is to evaluate the efficacy, safety, and economic benefits of AA therapy in preventing myopia in Chinese children aged 6-12 years with pre-myopia.</p><p><strong>Methods: </strong>The single-blind, multi-center, parallel-group, randomized controlled trial will involve 318 pre-myopic children from 20 different centers across China. After recruitment, these participants will be randomly assigned to two groups (the AA group and the control group) at a 1:1 ratio. The AA group will receive auricular point sticking therapy along with health education for a period of 24 weeks, while the control group will be provided the sham AA treatment and routine health education. The assessments of outcomes will be conducted at the start of this study, and then after 4, 8, 12, and 24 weeks. The primary outcome is the change in spherical equivalent refraction at various follow-up times. The secondary outcomes include the number of myopia cases, uncorrected visual acuity, axial length, corneal curvature radius, accommodation amplitude, retinal and choroidal thickness, and eye behavior management. In addition, the cost-effectiveness analysis will be used as the evaluation index for economic assessment.</p><p><strong>Discussion: </strong>The results of this research will provide evidence on the efficacy, safety, and economic benefits of AA therapy in preventing myopia among children aged 6-12 years with pre-myopia in China.</p>","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"3-12"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142945918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Static Magnetic Field Therapy on Pain Intensity, Functional Disability, Sleep Quality, and Depressive Symptoms in Patients with Mechanical Neck and Low Back Pain.","authors":"Onur Serdar Gencler, Duran Berker Cemil","doi":"10.1159/000542327","DOIUrl":"10.1159/000542327","url":null,"abstract":"<p><strong>Introduction: </strong>Mechanical neck pain (MNP) and mechanical low back pain (MLBP) can have a negative impact on the quality of life of patients and may be associated with high levels of disability. Magnetic field therapy has been used in the treatment of various diseases. This study was conducted to assess the effects of static magnetic field therapy generated by neodymium magnets in patients with MNP and MLBP.</p><p><strong>Methods: </strong>In this randomized, double-blind, sham-controlled, crossover study, patients with MNP and MLBP were randomly assigned to either the magnetic band or sham band treatment groups. After the initial 2-week phase (with participants randomly assigned to either treatment or sham control), both groups underwent a 1-week washout period. Subsequently, the groups were swapped and proceeded with a second 2-week phase. Visual analogue scale (VAS), Oswestry Low Back Pain Disability Questionnaire (ODI), Neck Disability Index (NDI), Insomnia Severity Index (ISI), and Patient Health Questionnaire-9 (PHQ-9) were used to evaluate the patients' pain severity, functional disability, sleep quality, and levels of depressive symptoms, respectively.</p><p><strong>Results: </strong>Of the 30 subjects, 17 (56.7%) had MLBP, whereas 13 (43.3%) had MNP. Magnetic band treatment (MBT) resulted in a significant decrease in the VAS score (p < 0.001) in all patients. MBT led to a significant decrease in the ODI score (p = 0.009) in patients with MLBP. A significant decrease in the NDI score was found in MBT (p < 0.001) in patients with MNP. The improvement in ISI and PHQ-9 scores was also significantly higher in MBT (p < 0.001).</p><p><strong>Conclusion: </strong>For patients with MNP and MLBP who have not experienced sufficient benefits from conventional treatments, neodymium magnets can be considered as an alternative treatment option due to their significant properties.</p>","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"45-54"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142602937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What a Study Is about Should Be Clear.","authors":"Axel Wiebrecht","doi":"10.1159/000539409","DOIUrl":"10.1159/000539409","url":null,"abstract":"","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"94-95"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141300250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Yoga Immersion and Gratitude as Pathways to Enhanced Well-Being.","authors":"Carolin Nögel, Mario Wenzel, Thomas Kubiak","doi":"10.1159/000545916","DOIUrl":"10.1159/000545916","url":null,"abstract":"<p><strong>Introduction: </strong>The popularity of yoga practice is steadily increasing. Previous studies have highlighted numerous beneficial effects of yoga. The present study aimed to investigate gratitude as a mediator of the relationship between yoga and well-being. Additionally, we examined the role of the involvement in yoga philosophy.</p><p><strong>Methods: </strong>A total of 344 yoga practitioners aged between 19 and 87 years completed an online survey. Yoga practice was operationalized via the frequency of practice in days per week. The Yoga Immersion Scale was used to measure the respondents' involvement in yoga philosophy.</p><p><strong>Results: </strong>We found positive associations between yoga frequency and well-being and between gratitude and well-being. There was no evidence for the hypothesized mediating effect of gratitude. Furthermore, yoga immersion did neither moderate the direct relationship between yoga and well-being nor the indirect relationship via gratitude; however, significant correlations between yoga immersion and gratitude and between yoga immersion and well-being were found.</p><p><strong>Conclusion: </strong>The results underscore the relevance of yoga immersion for yoga practice, but at the same time, new questions arise, particularly concerning the role of gratitude. Future research is needed to further gain a better understanding of these relationships.</p>","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"187-194"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143987048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Efficacy of Ayurveda Treatment Regimen and Letrozole along with Yoga Module in the Management of Unexplained and Anovulatory Female Infertility: Study Protocol for a Randomized Controlled Trial.","authors":"Anubha Chandla, Nalneesh Sharma, Kavita Vyas, Hemendar Mahajan, Varun Dutt, Arnav Bhavsar, Kirti Tripathi, Sarada Ota, Arunabh Tripathi","doi":"10.1159/000542655","DOIUrl":"10.1159/000542655","url":null,"abstract":"<p><strong>Introduction: </strong>Infertility is a significant health problem with psycho-social burden for couples. Ayurveda considers a holistic approach, including complex multimodal regimens in managing infertility. Increasing evidence has shown that Yoga as an adjuvant to infertility treatment increases pregnancy rates. Therefore, this research will investigate the comparative efficacy of Ayurveda regimen and letrozole, along with integration of Yoga in both groups in female infertility.</p><p><strong>Methods: </strong>The primary outcome, ovulation rate, will be measured through serial transvaginal sonography (TVS) for six consecutive menstrual cycles. The secondary outcome, conception rate, will be measured by definitive signs of pregnancy. Participants' quality of life will be assessed using the Ferti Quality of Life (FertiQOL) tool. The study will randomize 160 women aged 21-40 years diagnosed with anovulatory or unexplained infertility into two groups using permuted block randomization. Participants in group I will receive internal oleation with Phala Ghrita and mild purgation with Gandharvahasta (GH) oil for three consecutive cycles. Standard care group II participants will receive letrozole tablet once daily from day 3 to day 7 of the menstrual cycle for three cycles. The yoga instructor will take yoga sessions for participants of both groups for 6 months. This study will also use machine learning (ML) models to compare two regimens to predict improvements in outcome variables. The goal was to develop an online platform that aids personalized treatment planning and enhances clinical decision-making.</p><p><strong>Discussion: </strong>This will be the first study to generate evidence on the efficacy of integrated treatment regimens in female infertility, where predictive ML models will be developed.</p>","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"84-93"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Homeopathic and Conventional Treatments for Acute Upper Respiratory Tract Infections: Real-World Cohort Study on Recurrence and Antibiotic Prescriptions.","authors":"Norbert Banik, Sabine De Jaegere, Sabine Niederle, Thorsten Reineke","doi":"10.1159/000543183","DOIUrl":"10.1159/000543183","url":null,"abstract":"<p><strong>Introduction: </strong>The study evaluated the recurrence of acute upper respiratory tract infections (aURTIs) and the number of antibiotic prescriptions within a 12-month follow-up period in patients prescribed with either homeopathic medicines or medicines from one of four conventional medication classes for aURTI therapy.</p><p><strong>Methods: </strong>This explorative cohort study used real-world electronic healthcare data from the Disease Analyzer database (IQVIA). Included were patients of all ages from Germany with an index diagnosis of aURTI between 2010 and 2018, who had prescriptions for either homeopathic, conventional cough and cold, nasal, or throat medicines or nonopioid analgesics on the day of diagnosis or within 6 days afterwards. aURTI recurrence was assessed by multivariable logistic regression, the number of antibiotic prescriptions by multivariable negative binomial regression.</p><p><strong>Results: </strong>From 3,628,295 patients with aURTI diagnosis initially identified in the database in the relevant time interval, a total of 610,118 patients, fulfilling the in- and not violating the exclusion criteria, were retained for analysis. In the multivariate analyses on all patients, prescriptions of nasal medicines were associated with a significant, slightly higher (OR: 1.18, CI: 1.10-1.26, p < 0.001) risk of aURTI recurrence compared to homeopathic medicines within 12 months. Prescriptions of cough and cold (OR: 0.92, CI: 0.86-0.97, statistically significant, p = 0.005) as well as throat medicines (OR: 0.93, CI: 0.86-1.01, p = 0.086) and nonopioid analgesics (OR: 0.95, CI: 0.89-1.02, p = 0.181) were associated with slightly lower risk of aURTI recurrence compared to homeopathic medicines. In the analysis of the age-dependent subgroups, there were some deviations from the overall population in terms of statistical significance; however, the directions of the effect estimates were unchanged. Almost all results of negative binomial regression analyses assessing differences in the frequency of antibiotic prescriptions during follow-up, both in all patients and in the age-dependent subgroups, were statistically significant in favor of homeopathic medicines.</p><p><strong>Conclusion: </strong>The study demonstrated that follow-up recurrence and antibiotic prescriptions in patients with uncomplicated aURTI are at least comparable between patients treated with homeopathic and conventional medicines in real-world practice. Despite some methodological limitations inherent to the database used, the results of this study indicate that homeopathic medicines present a valuable therapeutic option for managing aURTI.</p><p><strong>Introduction: </strong>The study evaluated the recurrence of acute upper respiratory tract infections (aURTIs) and the number of antibiotic prescriptions within a 12-month follow-up period in patients prescribed with either homeopathic medicines or medicines from one of four conventional medication clas","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"13-25"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11892463/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142945863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Society Bulletins · Gesellschaftsmitteilungen.","authors":"","doi":"10.1159/000545096","DOIUrl":"10.1159/000545096","url":null,"abstract":"","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":"32 2","pages":"182-186"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143729153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ER+ HER2- Invasive Breast Cancer: Tumor Remission following Viscum Album Extract/Influenza Vaccine Treatment - A Report of 2 Cases.","authors":"Saphira Kaesbach, Alexander Hintze, Swantje Engelbrecht, Martin Wartenberg, Arnoud J Templeton","doi":"10.1159/000544082","DOIUrl":"10.1159/000544082","url":null,"abstract":"<p><strong>Introduction: </strong>Many patients with breast cancer use complementary and alternative medicine (CAM) including mistletoe preparations (Viscum album extracts, VAE). CAM alone has been associated with poor outcomes. Few, if any, confirmed breast cancer remissions have been reported with CAM treatment alone.</p><p><strong>Case presentations: </strong>Case 1: 60-year-old female with a histologically confirmed local recurrence of hormone receptor positive (HR+) Her2/neu negative (HER2-) breast cancer 3 years after the initial diagnosis and treatment. The patient declined conventional therapies and was treated with intratumoral VAE plus intratumoral influenza vaccine (IV) and concurrent VAE-induced hyperthermia. Lumpectomy 5 months later confirmed a near pathological complete remission (near pCR). Follow-up at 3 years confirms durable remission. Case 2: 57-year-old female with histologically confirmed HR+, HER2- right sided breast cancer with 2-[18F]FDG-PET/computed tomography (CT) positive metastatic disease who declined conventional treatment. The patient was treated with 17 monthly cycles of VAE-induced hyperthermia, eight of which included intratumoral VAE, four of these eight including intratumoral IV. Almost 2 years after treatment start, a follow-up 2-[18F]FDG-PET/CT showed marked morphological and metabolic reduction of breast tumor on the right side, stable local lymph node metastases in the right axilla, complete remission of pulmonary metastases, the single bone metastasis, and the majority of hilomediastinal lymph node metastases but a new metabolic highly active left adrenal lesion.</p><p><strong>Conclusions: </strong>Clinical studies of intratumoral VAE-influenza vaccine with concurrent VAE-induced hyperthermia in ER positive HER2/neu negative breast cancer are warranted.</p>","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"176-181"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11991746/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143406230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research Trends of Traditional Chinese Medicine Therapies on Chronic Obstructive Pulmonary Disease: A Bibliometric Analysis.","authors":"Chunyan Yang, Qiying He, Liuyang Huang, Hao Tian, Qin Luo, Guixing Xu, Mingsheng Sun, Sha Yang, Fanrong Liang, Pan Litao","doi":"10.1159/000541020","DOIUrl":"10.1159/000541020","url":null,"abstract":"<p><strong>Background: </strong>Traditional Chinese Medicine (TCM) therapies have shown great improvement in chronic obstructive pulmonary disease (COPD) patients, yet no bibliometric analysis on TCM therapies for COPD exists.</p><p><strong>Summary: </strong>A comprehensive literature search was conducted on TCM therapies for COPD within the past decade, utilizing the Web of Science (WOS) Core Collection and China National Knowledge Infrastructure (CNKI) databases. To analyze collaborative patterns among countries/regions, institutions, and authors, as well as identify influential references and emerging research trends, CiteSpace and VOSviewer software were employed. The dataset comprised 625 articles from WOS and 5,641 from CNKI, revealing a consistent growth in COPD-related TCM research over the past 10 years. China emerged as the leading contributor, with a predominant focus on TCM Universities. The American Journal of Respiratory and Critical Care Medicine was the most cited journal, while Medicine published the highest number of articles. Li JS was the most prolific author, and Barnes PJ was the most frequently cited researcher. Key studies by Leung RWM [Eur Respir J. 2013;41(5):1051-7], Li SY [BMC Complement Altern Med. 2012;12:197], and Polkey MI [Chest. 2018;153(5):1116-24] garnered significant attention. Keyword analysis highlighted the prominence of Tai Chi, Chinese herbal medicine, acupoint sticking, acupuncture, lung function, quality of life, and inflammation as core research themes.</p><p><strong>Key messages: </strong>Research on TCM therapies for COPD has gained growing attention over the past decade. Among the most commonly studied TCM interventions are Tai Chi, Chinese herbal medicine, acupoint sticking, and acupuncture. Lung function, quality of life, and inflammation have emerged as key areas of investigation and are likely to remain focal points for future research endeavors.</p>","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"67-83"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143051708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}