CNS SpectrumsPub Date : 2025-07-25DOI: 10.1017/S1092852925100448
Ambarin Faizi, Stephen M Stahl
{"title":"Drugs for Psychosis in People with Schizophrenia: What happens if you take them and what happens if you don't?","authors":"Ambarin Faizi, Stephen M Stahl","doi":"10.1017/S1092852925100448","DOIUrl":"https://doi.org/10.1017/S1092852925100448","url":null,"abstract":"","PeriodicalId":10505,"journal":{"name":"CNS Spectrums","volume":" ","pages":"1-26"},"PeriodicalIF":3.4,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144706596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CNS SpectrumsPub Date : 2025-07-21DOI: 10.1017/S1092852925100436
Manuel Glauco Carbone, Concetta Polizzi, Maria Maddalena Di Pasqua, Maria Regina Morales, Giovanna Perricone, Gaspare Cucinella, Rosalia Sutera, Sofia Burgio, Giulia Giordano
{"title":"Adherence to Medical Recommendations in High-Risk Pregnancy: Dispositional and Situational Predictors with a Focus on Emotional Reactivity.","authors":"Manuel Glauco Carbone, Concetta Polizzi, Maria Maddalena Di Pasqua, Maria Regina Morales, Giovanna Perricone, Gaspare Cucinella, Rosalia Sutera, Sofia Burgio, Giulia Giordano","doi":"10.1017/S1092852925100436","DOIUrl":"https://doi.org/10.1017/S1092852925100436","url":null,"abstract":"","PeriodicalId":10505,"journal":{"name":"CNS Spectrums","volume":" ","pages":"1-39"},"PeriodicalIF":3.4,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144674030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CNS SpectrumsPub Date : 2025-07-17DOI: 10.1017/S1092852925100424
Justin Fortune Creeden, Siddharth M Machiraju, Johansen B Amin, Stephen M Stahl
{"title":"From Betel Nuts to Cobenfy: How an Ancient Recreational Drug Gave Rise to a New Class of Schizophrenia Medications.","authors":"Justin Fortune Creeden, Siddharth M Machiraju, Johansen B Amin, Stephen M Stahl","doi":"10.1017/S1092852925100424","DOIUrl":"https://doi.org/10.1017/S1092852925100424","url":null,"abstract":"","PeriodicalId":10505,"journal":{"name":"CNS Spectrums","volume":" ","pages":"1-18"},"PeriodicalIF":3.4,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144648776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CNS SpectrumsPub Date : 2025-07-14DOI: 10.1017/S1092852925100357
Seetal Dodd, Laura Ospina-Pinillos, John S Markowitz
{"title":"Central nervous system stimulants in recreational and medical use.","authors":"Seetal Dodd, Laura Ospina-Pinillos, John S Markowitz","doi":"10.1017/S1092852925100357","DOIUrl":"10.1017/S1092852925100357","url":null,"abstract":"<p><p>Stimulants that act on the central nervous system have been used since antiquity for ritual and other uses. Organic chemistry techniques, especially those developed in Germany in the late 1800s, resulted in the isolation and structural determination of several important stimulants. Synthetic pathways for amphetamine and related stimulants were developed in the first half of the 19th century, and these new drugs were widely marketed. Awareness of abuse potential emerged soon after but was contested. Stimulants have been used to counteract fatigue and promote wakefulness during military operations, as well as to treat sleep disorders, since the 1930s. Methylphenidate was approved to treat children with behavioral problems in 1962, predating the recognition of attention deficit hyperactivity disorder (ADHD). Stimulant abuse became a political concern in the post-war period, initially with the use of \"pep-pills\" by long-haul truck drivers and later as drug dealing became common in night clubs, with new laws limiting availability passed in the early 1960s. They have also been used to increase athletic and cognitive performance. Stimulants are still first-line therapies for ADHD and some sleep disorders; however, newer-generation drugs have been developed with better safety profiles and lower abuse potential. Illicit stimulant use continues to be common in many countries.</p>","PeriodicalId":10505,"journal":{"name":"CNS Spectrums","volume":" ","pages":"e52"},"PeriodicalIF":3.4,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CNS SpectrumsPub Date : 2025-07-14DOI: 10.1017/S1092852925100369
Rennie Burke, Katherine D Warburton
{"title":"The Four Principles of Bioethics in Cases of Anosognosia.","authors":"Rennie Burke, Katherine D Warburton","doi":"10.1017/S1092852925100369","DOIUrl":"https://doi.org/10.1017/S1092852925100369","url":null,"abstract":"","PeriodicalId":10505,"journal":{"name":"CNS Spectrums","volume":" ","pages":"1-25"},"PeriodicalIF":3.4,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CNS SpectrumsPub Date : 2025-07-10DOI: 10.1017/S1092852925100394
Takesha Cooper
{"title":"Early Intervention for Schizophrenia: A Pathway to Improved Clinical Outcomes.","authors":"Takesha Cooper","doi":"10.1017/S1092852925100394","DOIUrl":"https://doi.org/10.1017/S1092852925100394","url":null,"abstract":"","PeriodicalId":10505,"journal":{"name":"CNS Spectrums","volume":" ","pages":"1-7"},"PeriodicalIF":3.4,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144599594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}