Clinical Psychopharmacology and Neuroscience最新文献_第8页

Differences in Electroencephalography Power and Asymmetry at Frontal Region in Young Adults with Attention-deficit/hyperactivity Disorder: A Quantitative Electroencephalography Study 青少年注意缺陷/多动障碍的脑电图功率差异和额叶不对称:定量脑电图研究

4区医学

Clinical Psychopharmacology and Neuroscience Pub Date : 2023-11-06 DOI: 10.9758/cpn.23.1104

Sung-Hoon Yoon, Jihye Oh, Yoo Hyun Um, Ho Jun Seo, Seung Chul Hong, Tae Won Kim, Jong-Hyun Jeong

引用次数: 0

Psilocybin, an Effective Treatment for Major Depressive Disorder in Adults - A Systematic Review 裸盖菇素对成人重度抑郁症的有效治疗——系统综述

4区医学

Clinical Psychopharmacology and Neuroscience Pub Date : 2023-10-16 DOI: 10.9758/cpn.23.1120

Tessa Watford, Naqash Masood

引用次数: 0

A Comparative Investigation of Functional Connectivity Utilizing Electroencephalography in Insomnia Patients With and Without Restless Leg Syndrome 不宁腿综合征失眠症患者与不宁腿综合征失眠症患者脑电功能连通性的比较研究

4区医学

Clinical Psychopharmacology and Neuroscience Pub Date : 2023-10-16 DOI: 10.9758/cpn.23.1117

Seo-Young Park, Young-Min Park, Yang Rae Kim

引用次数: 0

Mirtazapine Monotherapy for Antipsychotics-refractory Psychosis in a Patient with Very-late-onset Schizophrenia-like Psychosis: A Case Report 米氮平单药治疗抗精神病药物难治性精神病1例极晚发性精神分裂症样精神病

4区医学

Clinical Psychopharmacology and Neuroscience Pub Date : 2023-09-25 DOI: 10.9758/cpn.23.1103

Kanji Ueno, Makoto Ishitobi, Hirotaka Kosaka, Kei Ichijo, Yukihiro Nagase

引用次数: 0

The Association between Default-mode Network Functional Connectivity and Childhood Trauma on the Symptom Load in Male Adults with Methamphetamine Use Disorder 默认模式网络功能连接与童年创伤对成年男性甲基苯丙胺使用障碍症状负荷的影响

4区医学

Clinical Psychopharmacology and Neuroscience Pub Date : 2023-09-14 DOI: 10.9758/cpn.23.1079

Shyh-Yuh Wei, Tsung-Han Tsai, Tsung-Yu Tsai, Po See Chen, Huai-Hsuan Tseng, Yen Kuang Yang, Tianye Zhai, Yihong Yang, Tzu-Yun Wang

引用次数: 0

Transcranial Electrical Stimulation: Clinical Implication and Practice for Treatment of Psychiatric Illness 经颅电刺激:治疗精神疾病的临床意义与实践

4区医学

Clinical Psychopharmacology and Neuroscience Pub Date : 2023-09-11 DOI: 10.9758/cpn.23.1118

Chaeyeon Yang, Bori Jung, Seung-Hwan Lee

引用次数: 0

The Importance of Low-frequency Alpha (8−10 Hz) Waves and Default Mode Network in Behavioral Inhibition 低频α(8−10 Hz)波和默认模式网络在行为抑制中的重要性

4区医学

Clinical Psychopharmacology and Neuroscience Pub Date : 2023-05-30 DOI: 10.9758/cpn.22.1035

Yong-Wook Kim, Sungkean Kim, Min Jin Jin, Chang-Hwan Im, Seung-Hwan Lee

引用次数: 0

Hydroxychloroquine, Interleukin-6 Receptor Antagonists and Corticoid Treatments of Acute COVID-19 Infection: Psychiatric Symptoms and Mental Disorders 4 Months Later. 羟氯喹、白细胞介素-6受体拮抗剂和皮质激素治疗急性COVID-19感染:4个月后精神症状和精神障碍

IF 3.2 4区医学

Clinical Psychopharmacology and Neuroscience Pub Date : 2022-11-30 DOI: 10.9758/cpn.2022.20.4.762

Matthieu Gasnier, Walid Choucha, David Montani, Nicolas Noël, Céline Verstuyft, Francois Radiguer, Xavier Monnet, Laurent Becquemont, Emmanuelle Corruble, Romain Colle

{"title":"Hydroxychloroquine, Interleukin-6 Receptor Antagonists and Corticoid Treatments of Acute COVID-19 Infection: Psychiatric Symptoms and Mental Disorders 4 Months Later.","authors":"Matthieu Gasnier, Walid Choucha, David Montani, Nicolas Noël, Céline Verstuyft, Francois Radiguer, Xavier Monnet, Laurent Becquemont, Emmanuelle Corruble, Romain Colle","doi":"10.9758/cpn.2022.20.4.762","DOIUrl":"https://doi.org/10.9758/cpn.2022.20.4.762","url":null,"abstract":"Objective: Psychiatric symptoms and mental disorders are common after Coronavirus Disease-19 (COVID-19). Some drugs used to treat acute COVID-19 have psychiatric side effects. We assessed the psychiatric symptoms and mental disorders of patients treated for acute COVID-19 with hydroxychloroquine (HCQ), interleukin-6 receptor antagonists (anti-IL-6), and corticoids (CTC).Methods: We evaluated 177 patients in a day hospital 4 months after acute infection.Results: In a multivariate analysis, HCQ was associated with significant anxiety symptoms (odds ratio [OR] = 5.9, 95% confidence interval [95% CI] = 1.8-20.0, p = 0.003) and mental disorders (OR = 4.1, 95% CI = 1.2-13.9, p = 0.02). In a bivariate analysis with propensity matched cohorts, HCQ was associated with significant anxiety symptoms (9 patients [50.0%] with significant symptoms in the HCQ group versus 15 [20.1%] in the control group, OR = 3.8, 95% CI = 1.3-11.3, p = 0.01). Anti-IL-6 and CTC were not associated with significant psychiatric symptoms or mental disorders.Conclusion: We recommend monitoring psychiatric symptoms, especially anxiety, in patients treated with HCQ during COVID-19 infection. Further studies with larger samples and prospective assessments are needed to confirm our results.","PeriodicalId":10420,"journal":{"name":"Clinical Psychopharmacology and Neuroscience","volume":"20 4","pages":"762-767"},"PeriodicalIF":3.2,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/32/14/cpn-20-4-762.PMC9606425.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40560310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Cerebellar Gray Matter Volume and its Role in Executive Function, and Attention: Sex Differences by Age in Adolescents. 小脑灰质体积及其在执行功能和注意力中的作用:青少年年龄的性别差异。

IF 3.2 4区医学

Clinical Psychopharmacology and Neuroscience Pub Date : 2022-11-30 DOI: 10.9758/cpn.2022.20.4.621

Hayeon Kim, Bumhee Park, Shin-Young Kim, Jiyea Kim, Bora Kim, Kyu-In Jung, Seung-Yup Lee, Yerin Hyun, Bung-Nyun Kim, Subin Park, Min-Hyeon Park

{"title":"Cerebellar Gray Matter Volume and its Role in Executive Function, and Attention: Sex Differences by Age in Adolescents.","authors":"Hayeon Kim, Bumhee Park, Shin-Young Kim, Jiyea Kim, Bora Kim, Kyu-In Jung, Seung-Yup Lee, Yerin Hyun, Bung-Nyun Kim, Subin Park, Min-Hyeon Park","doi":"10.9758/cpn.2022.20.4.621","DOIUrl":"https://doi.org/10.9758/cpn.2022.20.4.621","url":null,"abstract":"Objective: This research measures the regional GMV (rGMV) of the cerebellum, attention, Executive Function (EF) and we aimed to identify their correlation and sex differences in children and adolescents.Methods: Subjects comprised 114 children (male = 62, female = 52, 12.44 ± 2.99 years old) from South Korea. Participants were divided into three groups by age (age 6-9, 10-13, and 14-17). The Stroop Color and Word Test (SCWT), Wisconsin Card Sorting Test (WCST), and Advanced Test of Attention (ATA) were used to estimate executive function. Magnetic resonance imaging (MRI) images were analyzed with Regional Voxel-Based Morphometry Analysis.Results: The correlations between cerebellar rGMV and SCWT, WCST, and ATA subcategories showed difference by age and sex. In 6-9 age group, girls showed more overall correlations with cerebellar regions than boys, in WCST Categories Completed and ATA results. In age 10-13 group, more regions of cerebellum corresponded to SCWT subcategories in girls. Nevertheless, more correlation between cerebellar rGMV, WCST subcategories and some ATA subtests were observed in boys in the same age group. In the adolescent group, aged 14-17, boys showed more correlation with cerebellar rGMV, while girls showed little correlation.Conclusion: This study highlights that sex-different cerebellum maturation in adolescence might be correlated with EF and attention. These results provides evidence that cerebellum modulates higher cognitive functioning during child development.","PeriodicalId":10420,"journal":{"name":"Clinical Psychopharmacology and Neuroscience","volume":"20 4","pages":"621-634"},"PeriodicalIF":3.2,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f1/cf/cpn-20-4-621.PMC9606426.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40669180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

DNA Methylation Pattern of Gene Promoters of MB-COMT, DRD2, and NR3C1 in Turkish Patients Diagnosed with Schizophrenia. 土耳其精神分裂症患者MB-COMT、DRD2和NR3C1基因启动子的DNA甲基化模式

IF 3.2 4区医学

Clinical Psychopharmacology and Neuroscience Pub Date : 2022-11-30 Epub Date: 2021-06-14 DOI: 10.9758/cpn.2022.20.4.685

Hasan Mervan Aytac, Yasemin Oyaci, Mustafa Pehlivan, Sacide Pehlivan

{"title":"DNA Methylation Pattern of Gene Promoters of MB-COMT, DRD2, and NR3C1 in Turkish Patients Diagnosed with Schizophrenia.","authors":"Hasan Mervan Aytac, Yasemin Oyaci, Mustafa Pehlivan, Sacide Pehlivan","doi":"10.9758/cpn.2022.20.4.685","DOIUrl":"https://doi.org/10.9758/cpn.2022.20.4.685","url":null,"abstract":"Objective: We aim to evaluate the methylation status of membrane-bound catechol-O-methyltransferase (MB-COMT) promotor, dopamine receptor D2 (DRD2), and nuclear receptor subfamily 3 group C member 1 (NR3C1) gene in pa- tients with SCZ by comparing healthy controls.Methods: A sample of 110 patients with SCZ and 100 age- and sex-matched healthy volunteers was included in the study. The interview was started by filling out data forms that included sociodemographic and clinical information. The Structured Clinical Interview for DSM-IV Axis I Disorders was used to confirming the diagnosis according to DSM-IV-TR criteria. Then the patients were evaluated with the Positive and Negative Symptoms Scale in terms of symp- tom severity. Methylation-specific polymerase chain reaction was used to determine the methylation status of MB-COMT promotor, DRD2 , and NR3C1 gene from DNA material.Results: When we compared the percentages of MB-COMT promotor, DRD2, and NR3C1 gene methylation status in SCZ patients with the healthy control group, the percentages of MB-COMT promotor (OR: 0.466; 95% CI: 0.268- 0.809; p = 0.006), DRD2 (OR: 0.439; 95% CI: 0.375-0.514; p < 0.001), and NR3C1 (OR: 0.003; 95% CI: 0.001- 0.011; p < 0.001) gene methylation status of SCZ was found to be significantly different from the control group. Whereas unmethylation of MB-COMT promotor and NR3C1 genes were associated with SCZ, the partial methylation of the DRD2 gene was related to the SCZ.Conclusion: The MB-COMT promotor, DRD2, and NR3C1 gene methylation status may be associated with the SCZ in the Turkish population.","PeriodicalId":10420,"journal":{"name":"Clinical Psychopharmacology and Neuroscience","volume":"20 4","pages":"685-693"},"PeriodicalIF":3.2,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/65/97/cpn-20-4-685.PMC9606422.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40557764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5