{"title":"Clinical Outcomes Following Simple or Complex Stenting for Coronary Bifurcation Lesions: A Meta-Analysis.","authors":"Qun Zhang, Hengshan Huan, Yu Han, Han Liu, Shukun Sun, Bailu Wang, Shujian Wei","doi":"10.1177/11795468221116842","DOIUrl":"https://doi.org/10.1177/11795468221116842","url":null,"abstract":"<p><strong>Background: </strong>Stent placement remains a challenge for coronary bifurcation lesions. While both simple and complex stenting strategies are available, it is unclear which one results in better clinical outcomes. This meta-analysis aims to explore the long-term prognosis following treatment with the 2 stenting strategies.</p><p><strong>Method: </strong>Randomized controlled trials found from searches of the PubMed, EMBASE, and Cochrane Central Register of Controlled Trials were included in this meta-analysis. The complex stent placement strategy was identified as the control group, and the simple stent placement strategy was identified as the experimental group. Data were synthesized with a random effects model. The quality of the randomized controlled trials was assessed by Jadad scale scores. The clinical endpoints at 6 months, 1 year, and 5 years were analyzed.</p><p><strong>Results: </strong>A total of 11 randomized controlled trials met the inclusion criteria. A total of 2494 patients were included in this meta-analysis. The odds ratio [OR] of the major adverse cardiac events (MACEs) at 6 months was 0.85 (95% confidence interval [CI] 0.53-1.35; <i>P</i> = .49, <i>I</i> <sup>2</sup> = 0%). The OR of the MACEs at 1 year was 0.61 (95% CI 0.36-1.05; <i>P</i> = .08, <i>I</i> <sup>2</sup> = 0%). The OR of the MACEs at 5 years was 0.69 (95% CI 0.51-0.92; <i>P</i> = .01, <i>I</i> <sup>2</sup> = 0%). Compared with the complex strategy, the simple strategy was associated with a lower incidence of MACEs at 5 years.</p><p><strong>Conclusion: </strong>Compared to the complex stenting strategy, the simple stenting strategy can better reduce the occurrence of long-term MACEs for coronary bifurcation lesions.</p>","PeriodicalId":10419,"journal":{"name":"Clinical Medicine Insights. Cardiology","volume":" ","pages":"11795468221116842"},"PeriodicalIF":3.0,"publicationDate":"2022-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3a/55/10.1177_11795468221116842.PMC9379967.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40708643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fauzie Rahman, Melati Noormaulidya Putri, M. Syarif, I. Aflanie, Endah Labati S, Husnul Fatimah, Zuhrufa Wanna Yolanda
{"title":"What Does Comorbid Status Implication with the End Status of Corona Virus Disease (Covid-19) Patients","authors":"Fauzie Rahman, Melati Noormaulidya Putri, M. Syarif, I. Aflanie, Endah Labati S, Husnul Fatimah, Zuhrufa Wanna Yolanda","doi":"10.52845/cmi/2022-3-3-2","DOIUrl":"https://doi.org/10.52845/cmi/2022-3-3-2","url":null,"abstract":"","PeriodicalId":10419,"journal":{"name":"Clinical Medicine Insights. Cardiology","volume":"47 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2022-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73650414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Treatment of Cancers with a Novel Combination of Re-PurposedPharmaceuticals and Some Nutriceuticals","authors":"R. Marsh, T. Itinteang","doi":"10.52845/cmi/2022-3-3-1","DOIUrl":"https://doi.org/10.52845/cmi/2022-3-3-1","url":null,"abstract":"","PeriodicalId":10419,"journal":{"name":"Clinical Medicine Insights. Cardiology","volume":"56 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2022-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77862301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sacroiliitis in patients with low backache with Normal Lumbosacral spine MRI","authors":"Dr. Bushra Mohsen Abdulla","doi":"10.52845/cmi/2022-3-2-1","DOIUrl":"https://doi.org/10.52845/cmi/2022-3-2-1","url":null,"abstract":"","PeriodicalId":10419,"journal":{"name":"Clinical Medicine Insights. Cardiology","volume":"86 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73041324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Charecteristics of Pressure Sore of Spinal Cord Injury Patients Attentded at Crp","authors":"Mahbub Hossain","doi":"10.52845/cmi/2022-3-2-5","DOIUrl":"https://doi.org/10.52845/cmi/2022-3-2-5","url":null,"abstract":"","PeriodicalId":10419,"journal":{"name":"Clinical Medicine Insights. Cardiology","volume":"35 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78528454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence and Determinants of Retinopathy among Patients with Diabetes Mellitus: Thiqar 2022","authors":"Wajida Saa'd Bunyan","doi":"10.52845/cmi/2022-3-2-4","DOIUrl":"https://doi.org/10.52845/cmi/2022-3-2-4","url":null,"abstract":"","PeriodicalId":10419,"journal":{"name":"Clinical Medicine Insights. Cardiology","volume":"5 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72759157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Outcome Of Corona Virus Disease-19 Patients In An Infectious Disease Center, Olodo, Ibadan, Oyo State, Nigeria","authors":"O. Alonge","doi":"10.52845/cmi/2022-3-2-2","DOIUrl":"https://doi.org/10.52845/cmi/2022-3-2-2","url":null,"abstract":"","PeriodicalId":10419,"journal":{"name":"Clinical Medicine Insights. Cardiology","volume":"71 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74474142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Lakey, Adam P Good, A. Wells, Ben Katz, Michael Alexander, D. Klokol, Mike K. S. Chan, M. Wong, D. Cox
{"title":"Maldi-Tof Analysis of Mitochondrial Peptides","authors":"J. Lakey, Adam P Good, A. Wells, Ben Katz, Michael Alexander, D. Klokol, Mike K. S. Chan, M. Wong, D. Cox","doi":"10.52845/cmi/2022-3-2-3","DOIUrl":"https://doi.org/10.52845/cmi/2022-3-2-3","url":null,"abstract":"","PeriodicalId":10419,"journal":{"name":"Clinical Medicine Insights. Cardiology","volume":"43 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85590684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of Comorbidity Burden on Cardiac Implantable Electronic Devices Outcomes.","authors":"Temitope Ajibawo, Oluwatimilehin Okunowo, Adeniyi Okunade","doi":"10.1177/11795468221108212","DOIUrl":"https://doi.org/10.1177/11795468221108212","url":null,"abstract":"Background: There is limited data on the impact of comorbidity burden on clinical outcomes of patients undergoing cardiac implantable electronic devices (CIED) implantation. Objectives: Our aim was to assess trends in CIED implantations and explore the relationship between comorbidity burden and outcomes in patients undergoing de novo implantations. Methods: Using the National Inpatient Sample database from 2000 to 2014, we identified adults ⩾18 years undergoing de novo CIED procedures. Comorbidity burden was assessed by Charlson comorbidity Index (CCI), and patients were classified into 4 categories based on their CCI scores (CCI = 0, CCI = 1, CCI = 2, CCI ⩾3). Annual implantation trends were evaluated. Logistic regression was conducted to measure the association between categorized comorbidity burden and outcomes. Results: A total of 3 103 796 de-novo CIED discharge records were identified from the NIS database. About 22.4% had a CCI score of 0, 28.2% had a CCI score of 1, 22% had a CCI score of 2, and 27.4 % had a CCI score ⩾3. Annual de-novo CIED implantations peaked in 2006 and declined steadily from 2010 to 2014. Compared to CCI 0, CCI ⩾3 was independently associated with increased odds of in-hospital mortality, bleeding, pericardial, and cardiac complications (all P < .05). Length of stay and hospital charges increased with increasing comorbidity burden. Conclusions: CCI is a significant predictor of adverse outcomes after CIED implantation. Therefore, comorbidity burden needs to be considered in the decision-making process for CIED implant candidates.","PeriodicalId":10419,"journal":{"name":"Clinical Medicine Insights. Cardiology","volume":" ","pages":"11795468221108212"},"PeriodicalIF":3.0,"publicationDate":"2022-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bf/f6/10.1177_11795468221108212.PMC9247999.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40467815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Is Spike Protein-Related Myocarditis Becoming a Common Disease?","authors":"Doepp, Manfred Md","doi":"10.52845/cmi/2022-3-1-5","DOIUrl":"https://doi.org/10.52845/cmi/2022-3-1-5","url":null,"abstract":"","PeriodicalId":10419,"journal":{"name":"Clinical Medicine Insights. Cardiology","volume":"33 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2022-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74494332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}