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The Current State-or Lack Thereof-of Screening and Prevention for Gynecologic Malignancies for Patients With Lynch Syndrome. 林奇综合征患者妇科恶性肿瘤筛查和预防的现状或不足。
IF 1.4 4区 医学
Clinical obstetrics and gynecology Pub Date : 2024-12-01 Epub Date: 2024-10-18 DOI: 10.1097/GRF.0000000000000892
Sharonne Holtzman, Madison Cox, Stephanie V Blank
{"title":"The Current State-or Lack Thereof-of Screening and Prevention for Gynecologic Malignancies for Patients With Lynch Syndrome.","authors":"Sharonne Holtzman, Madison Cox, Stephanie V Blank","doi":"10.1097/GRF.0000000000000892","DOIUrl":"https://doi.org/10.1097/GRF.0000000000000892","url":null,"abstract":"<p><p>Lynch syndrome (LS) is an autosomal dominant genetic disorder that results in an increased risk of ovarian and endometrial cancers. The aim of this paper was to explore the management of this risk through screening and prevention. Published materials and evidence were explored and summarized. This paper demonstrated that while there has been increased awareness and advances in the identification and diagnosis of patients with LS, recommendations for screening and prevention remain less evidence-based. In decisions of management of patients with LS, a shared decision-making model should be used considering individual patient goals.</p>","PeriodicalId":10415,"journal":{"name":"Clinical obstetrics and gynecology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142459635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Practical Evaluation of the Fetal Cardiac Function. 胎儿心脏功能实用评估。
IF 1.4 4区 医学
Clinical obstetrics and gynecology Pub Date : 2024-12-01 Epub Date: 2024-10-07 DOI: 10.1097/GRF.0000000000000899
Edgar Hernandez-Andrade, Beatrice Valentini, Donatella Gerulewicz
{"title":"Practical Evaluation of the Fetal Cardiac Function.","authors":"Edgar Hernandez-Andrade, Beatrice Valentini, Donatella Gerulewicz","doi":"10.1097/GRF.0000000000000899","DOIUrl":"https://doi.org/10.1097/GRF.0000000000000899","url":null,"abstract":"<p><p>The fetal heart adapts dynamically to nutrient and oxygen needs from all fetal organs. These continuous changes make it difficult to define normal/abnormal cardiac function based only on the evaluation of a few cycles. Many signs of fetal cardiac dysfunction have been suggested; however, very few can stand as true manifestations of cardiac deterioration, and none has emerged as a single reliable marker of cardiac dysfunction. It is the combination of abnormal findings that provides a more accurate assessment of the status of the fetal heart function.</p>","PeriodicalId":10415,"journal":{"name":"Clinical obstetrics and gynecology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142459634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
What About the Others? Clinical Management of Gynecologic Cancer Risk in Patients With Moderate-Risk Hereditary Cancer Genes ( ATM , BRIP1 , RAD51C , RAD51D , and PALB2 ). 其他基因如何？中度风险遗传性癌症基因（ATM、BRIP1、RAD51C、RAD51D 和 PALB2）患者的妇科癌症风险临床管理。
IF 1.4 4区 医学
Clinical obstetrics and gynecology Pub Date : 2024-12-01 Epub Date: 2024-09-26 DOI: 10.1097/GRF.0000000000000897
Ester I Goldfeld, Brianna E Kelly, Kari L Ring
{"title":"What About the Others? Clinical Management of Gynecologic Cancer Risk in Patients With Moderate-Risk Hereditary Cancer Genes ( ATM , BRIP1 , RAD51C , RAD51D , and PALB2 ).","authors":"Ester I Goldfeld, Brianna E Kelly, Kari L Ring","doi":"10.1097/GRF.0000000000000897","DOIUrl":"10.1097/GRF.0000000000000897","url":null,"abstract":"<p><p>Hereditary cancer syndromes associated with gynecologic malignancies account for up to 18% of all cases of ovarian, uterine, and cervical cancers, and identification of these syndromes has implications for cancer screening and risk reduction techniques in affected patients. The associated cancer risks with moderate-penetrance genes are rapidly evolving and present variable risks for the provider counseling the patient. In this review, we detail the cancer risk and management of patients with germline PV in the moderate-risk hereditary cancer genes ATM , BRIP1 , RAD51C , RAD51D , and PALB2 .</p>","PeriodicalId":10415,"journal":{"name":"Clinical obstetrics and gynecology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142342882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contributors: Genetics and Gynecologic Cancer: Opportunity and Nuance. 贡献者：遗传学与妇科癌症：机遇与微妙之处。
IF 1.4 4区 医学
Clinical obstetrics and gynecology Pub Date : 2024-12-01 Epub Date: 2024-10-18 DOI: 10.1097/01.grf.0001081336.90794.7f
{"title":"Contributors: Genetics and Gynecologic Cancer: Opportunity and Nuance.","authors":"","doi":"10.1097/01.grf.0001081336.90794.7f","DOIUrl":"https://doi.org/10.1097/01.grf.0001081336.90794.7f","url":null,"abstract":"","PeriodicalId":10415,"journal":{"name":"Clinical obstetrics and gynecology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142459577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Postpartum Ultrasound: An Indispensable Tool in the Labor Ward. 产后超声波：产房不可或缺的工具。
IF 1.4 4区 医学
Clinical obstetrics and gynecology Pub Date : 2024-12-01 Epub Date: 2024-10-18 DOI: 10.1097/GRF.0000000000000889
Wolfgang Henrich, Alexander Paping
{"title":"Postpartum Ultrasound: An Indispensable Tool in the Labor Ward.","authors":"Wolfgang Henrich, Alexander Paping","doi":"10.1097/GRF.0000000000000889","DOIUrl":"https://doi.org/10.1097/GRF.0000000000000889","url":null,"abstract":"<p><p>Postpartum hemorrhage can occur because of different conditions. Apart from placental remnants and uterine atony, less common causes include uterine rupture, placental polyps, arteriovenous malformations, and pseudoaneurysms. Ultrasound plays a key role in the precise definition of the underlying pathology, which is necessary to initiate the appropriate therapy. It also helps to depict intraabdominal hematomas and uterine scar dehiscence, 2 conditions that do not necessarily lead to postpartum hemorrhage but are associated with increased maternal morbidity. This article presents 52 ultrasound images together with clinical and histopathologic images to give an overview of both frequent and rare pathologies in the postpartum period.</p>","PeriodicalId":10415,"journal":{"name":"Clinical obstetrics and gynecology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142459633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Index. 索引。
IF 1.4 4区 医学
Clinical obstetrics and gynecology Pub Date : 2024-12-01 Epub Date: 2024-10-18 DOI: 10.1097/01.grf.0001081344.93988.16
{"title":"Index.","authors":"","doi":"10.1097/01.grf.0001081344.93988.16","DOIUrl":"https://doi.org/10.1097/01.grf.0001081344.93988.16","url":null,"abstract":"","PeriodicalId":10415,"journal":{"name":"Clinical obstetrics and gynecology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142459578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Uptake of Cascade Genetic Testing for Hereditary Breast and Ovarian Cancer: A Systematic Review and Meta-Analysis. 遗传性乳腺癌和卵巢癌的级联基因检测接受率：系统回顾与元分析》。
IF 1.4 4区 医学
Clinical obstetrics and gynecology Pub Date : 2024-12-01 Epub Date: 2024-10-18 DOI: 10.1097/GRF.0000000000000895
Muhammad Danyal Ahsan, Isabelle R Chandler, Samantha Min, Benjamin Grant, Michelle Primiano, Jamieson Greenwald, Tamar N Soussana, Becky Baltich Nelson, Charlene Thomas, Eloise Chapman-Davis, Ravi N Sharaf, Melissa K Frey
{"title":"Uptake of Cascade Genetic Testing for Hereditary Breast and Ovarian Cancer: A Systematic Review and Meta-Analysis.","authors":"Muhammad Danyal Ahsan, Isabelle R Chandler, Samantha Min, Benjamin Grant, Michelle Primiano, Jamieson Greenwald, Tamar N Soussana, Becky Baltich Nelson, Charlene Thomas, Eloise Chapman-Davis, Ravi N Sharaf, Melissa K Frey","doi":"10.1097/GRF.0000000000000895","DOIUrl":"10.1097/GRF.0000000000000895","url":null,"abstract":"<p><p>This is a systematic review and meta-analysis evaluating the uptake of cascade genetic testing for hereditary breast and ovarian cancer syndrome. Among 30 studies included for meta-analysis, the uptake of cascade genetic testing was 33% (95% CI 25%-42%), with higher uptake rates among females compared with male relatives, and among first-degree compared with second-degree relatives. These findings indicate suboptimal uptake of cascade genetic testing among people at risk for hereditary breast and ovarian cancer syndrome, representing a missed opportunity for cancer prevention and early detection. There is a need for interventions to improve uptake rates.</p>","PeriodicalId":10415,"journal":{"name":"Clinical obstetrics and gynecology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142459636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contributors: Hot Topics in Obstetrics and Gynecology Medical Education. 撰稿人：妇产科医学教育热点话题。
IF 1.4 4区 医学
Clinical obstetrics and gynecology Pub Date : 2024-09-01 Epub Date: 2024-07-25 DOI: 10.1097/01.grf.0001027868.24479.b9
{"title":"Contributors: Hot Topics in Obstetrics and Gynecology Medical Education.","authors":"","doi":"10.1097/01.grf.0001027868.24479.b9","DOIUrl":"10.1097/01.grf.0001027868.24479.b9","url":null,"abstract":"","PeriodicalId":10415,"journal":{"name":"Clinical obstetrics and gynecology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141765693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Maternal Sepsis. 产妇败血症。
IF 1.4 4区 医学
Clinical obstetrics and gynecology Pub Date : 2024-09-01 Epub Date: 2024-07-05 DOI: 10.1097/GRF.0000000000000881
Claudia Nieuwoudt, Sarah E White, R Phillips Heine, Talla Motakef Widelock
{"title":"Maternal Sepsis.","authors":"Claudia Nieuwoudt, Sarah E White, R Phillips Heine, Talla Motakef Widelock","doi":"10.1097/GRF.0000000000000881","DOIUrl":"10.1097/GRF.0000000000000881","url":null,"abstract":"<p><p>Sepsis is the second leading cause of pregnancy-related mortality in the United States. Early recognition, treatment, and escalation of care for the obstetric patient affected by sepsis mitigate the risk of mortality and improve patient outcomes. In this article, we provide an overview of maternal sepsis and address topics of maternal pathophysiology, early warning signs, diagnostic criteria, early goal-directed therapy, and contemporary critical care practices. We also present an overview of common etiologies of maternal sepsis and suggested treatment approaches.</p>","PeriodicalId":10415,"journal":{"name":"Clinical obstetrics and gynecology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141533855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Redesigning Continuous Professional Development: Aligning Learning Needs With Clinical Practice. 重新设计持续专业发展：将学习需求与临床实践相结合。
IF 1.4 4区 医学
Clinical obstetrics and gynecology Pub Date : 2024-09-01 Epub Date: 2024-06-17 DOI: 10.1097/GRF.0000000000000878
Maya M Hammoud, Zachary Schoppen, Lori R Berkowitz, David Marzano
{"title":"Redesigning Continuous Professional Development: Aligning Learning Needs With Clinical Practice.","authors":"Maya M Hammoud, Zachary Schoppen, Lori R Berkowitz, David Marzano","doi":"10.1097/GRF.0000000000000878","DOIUrl":"10.1097/GRF.0000000000000878","url":null,"abstract":"<p><p>Continuous professional development (CPD) in health care refers to the process of lifelong learning including the acquisition of new competencies, knowledge, and professional growth throughout the career of a health care professional. Since implementation, there has seen little change or innovation in CPD. This perspective will review the current state of CPD, including the challenges in traditional CPD models, foundations and strategies for redesign to meet the needs of current and future physicians, and suggestions for changes to modernize CPD. Precision education and the use of technology, including artificial intelligence, and their application to CPD will be discussed.</p>","PeriodicalId":10415,"journal":{"name":"Clinical obstetrics and gynecology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141330523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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