Clinical Obesity最新文献

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Impact of the swallowable Allurion intragastric balloon on body weight and composition: An Ecuadorian experience 可吞咽的 Allurion 胃内球囊对体重和组成的影响:厄瓜多尔的经验。
IF 2.2
Clinical Obesity Pub Date : 2024-09-22 DOI: 10.1111/cob.12705
Bernarda Patiño Araujo, Karla Elizabeth Duque Jácome, María Emilia Salgado Báez, Gabriel Villavicencio Logroño, Napoleón Salgado Macías
{"title":"Impact of the swallowable Allurion intragastric balloon on body weight and composition: An Ecuadorian experience","authors":"Bernarda Patiño Araujo,&nbsp;Karla Elizabeth Duque Jácome,&nbsp;María Emilia Salgado Báez,&nbsp;Gabriel Villavicencio Logroño,&nbsp;Napoleón Salgado Macías","doi":"10.1111/cob.12705","DOIUrl":"10.1111/cob.12705","url":null,"abstract":"<div>\u0000 \u0000 <p>People with excess weight and obesity compose 64.5% of the Ecuadorian population. The Allurion Intragastric Balloon (IGB) is a noninvasive weight loss alternative for patients ineligible for other bariatric procedures. The impact of the procedure on weight loss and body composition, along with insertion complications and secondary effects were investigated. This is a single-centre retrospective study of patients who underwent Allurion IGB insertion from July 2020 to March 2021. This study followed 167 patients for 12 months after EIGB insertion. Our sample had a mean initial weight of 83.6 ± 13.8 kg and initial body mass index of 31.3 ± 3.6 kg/m<sup>2</sup>. Percentage total weight loss was 4.65% ± 0.56%, 8.5% ± 4%, 12.29% ± 4.65%, 15.68% ± 5.22%, 17.14% ± 6.05%, and 14.68% ± 18.02% for months 1, 2, 3, 4, 6 and 12, respectively. In the fourth month, 92 patients (56.4%) had lost ≥50% excess body weight; at month 6, 104 patients (67.5%) achieved this goal. Regarding body composition, body fat percentage started at 38.99% ± 7.92%, and at month 6 was 35.67% ± 6.84%, this was the only significance in the statistical analysis.This study aligns with the literature's safety and efficacy results for the Allurion IGB while illustrating the need for further research regarding weight behaviour after its expulsion.</p>\u0000 </div>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"15 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142281356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of providing energy expenditure information to guide weight loss interventions in people with obesity: A randomized controlled trial 为肥胖症患者提供能量消耗信息以指导减肥干预的效果:随机对照试验。
IF 2.2
Clinical Obesity Pub Date : 2024-09-17 DOI: 10.1111/cob.12703
Jonathan Z. M. Lim, Andrew Williams, Jamie Burgess, James O'Connell, Michaela James, Andy Cross, David Hughes, Daniel J. Cuthbertson, Uazman Alam, John P. H. Wilding
{"title":"Efficacy of providing energy expenditure information to guide weight loss interventions in people with obesity: A randomized controlled trial","authors":"Jonathan Z. M. Lim,&nbsp;Andrew Williams,&nbsp;Jamie Burgess,&nbsp;James O'Connell,&nbsp;Michaela James,&nbsp;Andy Cross,&nbsp;David Hughes,&nbsp;Daniel J. Cuthbertson,&nbsp;Uazman Alam,&nbsp;John P. H. Wilding","doi":"10.1111/cob.12703","DOIUrl":"10.1111/cob.12703","url":null,"abstract":"<p>Resting energy expenditure (REE) and metabolic fuel utilization (carbohydrate or fat) proxied by respiratory quotient (RQ) from indirect calorimetry enables more precise measurement of energy needs and fat oxidation capacity. The study compared the effectiveness of providing energy expenditure information during diet and exercise weight intervention versus standard of care (SOC) on weight loss outcomes. Fifty-two participants with obesity were recruited from a specialist weight loss service, randomized 1:1 to intervention (INT) or SOC only. Participants in INT received four-weekly dietetic counselling, using biofeedback from energy expenditure data to recommend caloric restriction and physical activity goals, in addition to SOC. The primary outcome was the mean difference in weight loss between both groups after 24 weeks. Secondary outcomes include participant acceptability and tolerability using indirect calorimetry. Participants in the INT group demonstrated additional weight loss (−2.3 kg [95% CI: −3.1, −1.5]; <i>p</i> &lt;.001), reduced waist circumference (−3.9 cm [95% CI: −5.48, −2.26]; <i>p</i> &lt;.001), and decreased body fat percentage (−1.5% [95% CI:−2.31, −0.72], <i>p</i> &lt;.001), compared to SOC, after adjusting for baseline body mass index, age, and sex. Forty-two percent (10/24) of participants in INT group achieved the minimum clinically significant threshold of 5% weight loss from baseline, compared to 8% (2/26) in the SOC group (<i>p</i> = .007). Participant acceptability and tolerability of indirect calorimetry were high, with mean scores of 4.5 ± 0.6 and 4.2 ± 0.7 (5-point Likert scale). The study establishes the safety and practical integration of biofeedback using indirect calorimetry promoting improved self-regulation and enhancing weight loss.</p>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"15 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11706736/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142281355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Therapeutic inertia in obesity management among people living with obesity from the perspective of general/family practitioners in Canada: A mixed-methods study 从加拿大全科/家庭医生的角度看肥胖症患者肥胖症管理中的治疗惰性:混合方法研究。
IF 2.2
Clinical Obesity Pub Date : 2024-09-03 DOI: 10.1111/cob.12701
David C. W. Lau, Ian Patton, Reena Lavji, Adel Belloum, Ginnie Ng, Renuca Modi
{"title":"Therapeutic inertia in obesity management among people living with obesity from the perspective of general/family practitioners in Canada: A mixed-methods study","authors":"David C. W. Lau,&nbsp;Ian Patton,&nbsp;Reena Lavji,&nbsp;Adel Belloum,&nbsp;Ginnie Ng,&nbsp;Renuca Modi","doi":"10.1111/cob.12701","DOIUrl":"10.1111/cob.12701","url":null,"abstract":"<p>This mixed-methods study aimed to explore factors contributing to therapeutic inertia among people living with obesity in Canada from the perspective of general/family practitioners (GP/FPs). One-on-one interviews and online surveys guided by the Theoretical Domains Framework were conducted. A total of 20 general/family practitioners were interviewed and 200 general/family practitioners were surveyed. Key findings from interviews were used to guide the development of the survey. Spearman's correlation analysis evaluated the association between general/family practitioners theme domain scores and their familiarity with the 2020 Canadian Adult Obesity Clinical Practice Guidelines. The 200 general/family practitioners surveyed provided representation across Canada, with diversity in age, background, and gender. The most prominent domains related to therapeutic inertia that were positively influenced by familiarity with Clinical Practice Guidelines were <i>Beliefs about Capabilities</i> (<i>r</i><sub>s</sub> = .27; <i>p</i> &lt; .01), <i>Skills</i> (<i>r</i><sub>s</sub> = .23; <i>p</i> &lt; .01), <i>Behavioural Regulation</i> (<i>r</i><sub>s</sub> = .24; <i>p</i> &lt; .01) and <i>Emotions</i> (<i>r</i><sub>s</sub> = .23; <i>p</i> &lt; .01). Irrespective of their familiarity with Clinical Practice Guidelines, most general/family practitioners reported that environmental and contextual barriers impact obesity management. Particularly, while financial barriers were reported by participants regardless of Clinical Practice Guidelines familiarity, general/family practitioners familiar with Clinical Practice Guidelines more often reported having time to discuss obesity management with patients. This study identified perceptions, resource and training considerations that contribute to healthcare decision-making and therapeutic inertia in obesity management among general/family practitioners and highlighted key areas to target with interventions in primary care to facilitate obesity management, which should be multi-faceted, with a focus on incorporating obesity education into healthcare providers training programs and improving systemic and financial support.</p>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"15 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11706748/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142125043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unravelling the ties that bind: The intersection of obesity, osteoarthritis, and inflammatory pathways with emphasis on glucagon-like peptide-1 agonists 解开联系的纽带:肥胖、骨关节炎和炎症途径的交叉点,重点是胰高血糖素样肽-1 激动剂。
IF 2.2
Clinical Obesity Pub Date : 2024-08-16 DOI: 10.1111/cob.12700
Naadir Jamal, William Hollabaugh, Leon Scott, Sahar Takkouche
{"title":"Unravelling the ties that bind: The intersection of obesity, osteoarthritis, and inflammatory pathways with emphasis on glucagon-like peptide-1 agonists","authors":"Naadir Jamal,&nbsp;William Hollabaugh,&nbsp;Leon Scott,&nbsp;Sahar Takkouche","doi":"10.1111/cob.12700","DOIUrl":"10.1111/cob.12700","url":null,"abstract":"<p>This narrative review article explores the complex interplay between obesity, osteoarthritis, and their associated inflammatory cascades, offering a deeper understanding of the underlying of mechanisms of inflammation and potential therapeutic interventions targeting both diseases. Through examination of the shared inflammatory pathway of obesity and osteoarthritis, our objective is to directly elucidate the relationship between these two conditions, highlighting the promising role of glucagon-like peptide-1 agonists in modulating inflammation and its therapeutic implications for patients with obesity and osteoarthritis.</p>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"15 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11706737/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141995456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endoscopic duodenal-jejunal bypass liner treatment of moderate obstructive sleep apnoea—A pilot study 内镜十二指肠空肠分流术治疗中度阻塞性睡眠呼吸暂停--一项试验研究。
IF 2.2
Clinical Obesity Pub Date : 2024-08-11 DOI: 10.1111/cob.12694
Mahender Yadagiri, Fiona Y. Kinney, Natalie Ashman, John P. Bleasdale, Edward N. Fogden, Mark R. Anderson, Christopher Walton, Michael A. Greenstone, Robert E. J. Ryder
{"title":"Endoscopic duodenal-jejunal bypass liner treatment of moderate obstructive sleep apnoea—A pilot study","authors":"Mahender Yadagiri,&nbsp;Fiona Y. Kinney,&nbsp;Natalie Ashman,&nbsp;John P. Bleasdale,&nbsp;Edward N. Fogden,&nbsp;Mark R. Anderson,&nbsp;Christopher Walton,&nbsp;Michael A. Greenstone,&nbsp;Robert E. J. Ryder","doi":"10.1111/cob.12694","DOIUrl":"10.1111/cob.12694","url":null,"abstract":"<p>We aimed to assess the extent to which people with type 2 diabetes or pre-diabetes, obesity (BMI 30–45 kg/m<sup>2</sup>) and moderate obstructive sleep apnoea (OSA) requiring continuous positive airway pressure ventilation (CPAP) were able to discontinue CPAP following EndoBarrier-related weight loss. We assessed sleep and metabolic parameters before, during and after EndoBarrier in 12 participants with moderate OSA requiring CPAP (75% female, 8/12 [66%] type 2 diabetes, 4/12 [34%] prediabetes, mean ± SD age 52.6 ± 9.7 years, BMI 37.4 ± 3.5 kg/m<sup>2</sup>, median duration of OSA while on CPAP 9.0 [7.0–15.0] months). With EndoBarrier in-situ, mean ± SD Apnoea Hypopnoea Index (AHI) fell by 9.1 ± 5.0 events/h from 18.9 ± 3.8 to 9.7 ± 3.0 events/h (<i>p</i> &lt; .001) with an associated reduction in symptoms of daytime sleepiness (mean Epworth Sleepiness Score) such that all the 12 participants no longer required CPAP according to National Institute for Health and Care Excellence criteria. After EndoBarrier removal, 10/12 (83%) patients attended follow-up and at 12 months after removal, AHI remained below 15 in 5/10 (50%) patients but in other five the AHI rose above 15 such that restarting CPAP was recommended as justified by their symptoms. Rather than restart CPAP, two patients lost the regained weight and their AHI dropped below 15 again. Thus, 7/10 (70%) of patients were able to remain off CPAP 12 or more months after EndoBarrier removal. These results demonstrate major benefit of EndoBarrier in moderate OSA, allowing all patients to discontinue CPAP during treatment, and with maintenance of improvement at follow-up in 70%. They confirm previously demonstrated metabolic improvements in diabetes and obesity.</p>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"14 6","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cob.12694","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141916201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations between obesity and severity of coronavirus disease 2019 in Brazilian inpatients: A 2021 secondary data analysis 巴西 2019 年住院病人肥胖与冠状病毒疾病严重程度之间的关系:2021年二手数据分析。
IF 2.2
Clinical Obesity Pub Date : 2024-08-09 DOI: 10.1111/cob.12698
Gabrielle Ribeiro Sena, Tiago Pessoa Ferreira de Lima, Michelle Lima de Carvalho Silva, Paloma Gomes Tavares Sette, Gabriela Carla dos Santos Costa, Amanda Mendes da Fonseca Benvindo, Maria Júlia Gonçalves de Mello, Guilherme Jorge Costa
{"title":"Associations between obesity and severity of coronavirus disease 2019 in Brazilian inpatients: A 2021 secondary data analysis","authors":"Gabrielle Ribeiro Sena,&nbsp;Tiago Pessoa Ferreira de Lima,&nbsp;Michelle Lima de Carvalho Silva,&nbsp;Paloma Gomes Tavares Sette,&nbsp;Gabriela Carla dos Santos Costa,&nbsp;Amanda Mendes da Fonseca Benvindo,&nbsp;Maria Júlia Gonçalves de Mello,&nbsp;Guilherme Jorge Costa","doi":"10.1111/cob.12698","DOIUrl":"10.1111/cob.12698","url":null,"abstract":"<div>\u0000 \u0000 <p>In the backdrop of the global obesity pandemic, recognized as a notable risk factor for coronavirus disease 2019 (COVID-19) complications, the study aims to explore clinical and epidemiological attributes of hospitalized COVID-19 patients throughout 2021 in Brazil. Focused on four distinct age cohorts, the investigation scrutinizes parameters such as intensive care unit (ICU) admission frequency, invasive mechanical ventilation (IMV) usage, and in-hospital mortality among individuals with and without obesity. Using a comprehensive cross-sectional study methodology, encompassing adult COVID-19 cases, data sourced from the Influenza Epidemiological Surveillance Information System comprises 329 206 hospitalized patients. Of these individuals, 26.3% were affected by obesity. Analysis reveals elevated rates of ICU admissions, increased dependence on IMV, and heightened in-hospital mortality among the individuals with obesity across all age groups (<i>p</i> &lt; .001). Logistic regression, adjusting for confounding variables, underscores a progressively rising odds ratio for mortality in younger age brackets: 1.2 (95%CI 1.1–1.3) for those under 50 years, 1.1 (95%CI 1.0–1.2) for the 50–59 age group, and 1.1 (95%CI 1.0–1.2) for the 60–69 age group. Conversely, no significant mortality difference is observed for patients over 70 years (OR: 0.972, 95%CI 0.9–1.1). In summary, hospitalized COVID-19 patients with obesity, particularly in younger age groups, exhibit elevated rates of ICU admission, IMV requirement, and in-hospital mortality compared with the control group. Notably, the ‘obesity paradox’ is not evident among hospitalized COVID-19 patients in 2021.</p>\u0000 </div>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"14 6","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141909791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emotion dysregulation and obesity: A conceptual review of the literature 情绪失调与肥胖:文献概念回顾。
IF 2.2
Clinical Obesity Pub Date : 2024-08-09 DOI: 10.1111/cob.12699
Molly E. Atwood
{"title":"Emotion dysregulation and obesity: A conceptual review of the literature","authors":"Molly E. Atwood","doi":"10.1111/cob.12699","DOIUrl":"10.1111/cob.12699","url":null,"abstract":"<div>\u0000 \u0000 <p>Problematic eating behaviours are prevalent in individuals living with obesity and have been linked to weight gain over time. Furthermore, there is evidence that heightened negative emotionality is common in a subset of individuals living with obesity and that negative emotions often precede problematic eating behaviours. Consequently, several theories have highlighted emotion dysregulation as a potential explanatory mechanism of this relationship. However, to date, no comprehensive review has compiled the specific ways in which individuals living with obesity exhibit emotion dysregulation. The present review utilizes Gratz and Roemer's (2004) multidimensional conceptualization of emotion regulation and dysregulation as a framework to summarize the extant literature on emotion dysregulation in obesity. Specifically, this review examines research related to: (1) awareness and clarity of emotions; (2) acceptance of, and willingness to experience, emotion; (3) the ability to remain goal directed and inhibit impulsive behaviour when distressed; and (4) access to emotion regulation strategies. Overall, findings from the present review demonstrate that individuals living with obesity exhibit deficits in emotion clarity, and experience difficulty inhibiting impulsive behaviour and remaining goal directed when experiencing emotion. Strengths and limitations of the literature are reviewed, and future research directions and clinical implications are discussed in light of these findings.</p>\u0000 </div>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"14 6","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141906115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Obesity in European nursing homes participating in nutritionDay 2016–2021—Prevalence and resident characteristics 参加 "2016-2021 年营养日 "活动的欧洲养老院中的肥胖症--患病率和住院者特征。
IF 2.2
Clinical Obesity Pub Date : 2024-08-04 DOI: 10.1111/cob.12697
Isabel Galicia Ernst, Isabella Worf, Silvia Tarantino, Michael Hiesmayr, Dorothee Volkert
{"title":"Obesity in European nursing homes participating in nutritionDay 2016–2021—Prevalence and resident characteristics","authors":"Isabel Galicia Ernst,&nbsp;Isabella Worf,&nbsp;Silvia Tarantino,&nbsp;Michael Hiesmayr,&nbsp;Dorothee Volkert","doi":"10.1111/cob.12697","DOIUrl":"10.1111/cob.12697","url":null,"abstract":"<p>The objective of this study is to assess obesity prevalence and characterize European nursing home (NH) residents with obesity comprehensively. Cross-sectional nutritionDay data from 2016 to 2021. Descriptive characterization of European NH residents ≥65 years with and without obesity. Binomial logistic regression to identify factors associated with obesity. A total of 11 327 residents (73.8% female, 86.4 ± 7.9 years, mean body mass index 25.3 ± 5.4 kg/m<sup>2</sup>) from 12 countries were analysed. Obesity prevalence was 17.7%, mostly class I (13.0%). Taking ≥5 drugs/day (OR 1.633; 95% confidence intervals 1.358–1.972), female sex (1.591; 1.385–1.832), being bed/chair-bound (1.357; 1.146–1.606), and having heart/circulation/lung disease (1.276; 1.124–1.448) was associated with increased obesity risk, older age (0.951; 0.944–0.958), mild (0.696; 0.601–0.805) and severe (0.591; 0.488–0.715) dementia, eating less than ¾ of lunch on nutritionDay (0.669; 0.563–0.793), needing assistance for eating (0.686; 0.569–0.825), and being identified by NH staff at risk for (0.312; 0.255–0.380) or with malnutrition (0.392; 0.236–0.619) decreased obesity risk. Almost one in five residents in European NH participating in nutritionDay is affected by obesity. Through a wide exploratory analysis, including data from 12 European countries, we confirmed previous findings and identified additional factors associated with obesity that should be considered in the daily care of affected residents.</p>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"14 6","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cob.12697","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141888603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Undetected and undiagnosed comorbidity in patients with obesity undergoing bariatric surgery—Results from the Berlin Bariatric Cohort study 接受减肥手术的肥胖症患者未被发现和诊断的合并症--柏林减肥队列研究的结果。
IF 2.2
Clinical Obesity Pub Date : 2024-07-25 DOI: 10.1111/cob.12695
Wolfgang Pommer, Hendrik Krautschneider, Susanne D. Kuhlmann, Gerold Koplin, Martin Susewind, Oleg Tsuprykov
{"title":"Undetected and undiagnosed comorbidity in patients with obesity undergoing bariatric surgery—Results from the Berlin Bariatric Cohort study","authors":"Wolfgang Pommer,&nbsp;Hendrik Krautschneider,&nbsp;Susanne D. Kuhlmann,&nbsp;Gerold Koplin,&nbsp;Martin Susewind,&nbsp;Oleg Tsuprykov","doi":"10.1111/cob.12695","DOIUrl":"10.1111/cob.12695","url":null,"abstract":"<p>The quality of general obesity management before bariatric surgery (BS) is rarely investigated. Inadequate information regarding undetected and undiagnosed comorbidities (UUCs) in individuals with obesity may influence the penetration, risks, and outcomes of BS. We conducted a cohort study involving a pre-specified medical check-up in a cooperation between a BS department and an outpatient medical centre. A total of 1068 patients (74.4% women) were enrolled in the study. The mean age was 42.1 years (standard deviation [SD] 11.9) and the mean body mass index (BMI) was 46.1 (SD 6.91). The onset of obesity occurred in 11.4% of patients during childhood, 47.2% during schooltime/adolescence, 41.4% in adulthood. Gender differences were observed: men had higher BMI, systolic blood pressure, and impaired metabolic state (including diabetes, dyslipidemia, and liver disease with <i>p</i>-values &lt;.001 for all). Women had lower haemoglobin levels, impaired iron status, lower albumin levels (<i>p</i> &lt; .001), and increased C-reactive protein levels (<i>p</i> &lt; .05). The prevalence of UUC conditions (percentage of cases) was as follows: arterial hypertension, 53%; decreased cystatin C clearance, 57%; dyslipidemia, 41%; fatty liver, 40%; iron deficiency, 37%; diabetes mellitus, 34%; vitamin D deficiency, 32%; chronic pain syndrome, 23%; liver fibrosis, 12%; obstructive sleep apnea, 10%; and vitamin deficiencies (vitamin B<sub>12</sub>, folic acid, vitamin K<sub>1</sub>) &lt;10%. Undiagnosed hypertension was more prevalent in younger women, and nutritional deficits were associated with high BMI in both genders. Older age and high BMI were associated with undiagnosed diabetes and decreased glomerular filtration rate in both genders, and with liver fibrosis in men. UUC are highly prevalent in individuals undergoing BS. A refined assessment is recommended to improve health conditions and outcome in these candidates.</p>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"14 6","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cob.12695","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141757543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Indian multicentre real-world study on long-term quality of life outcomes following bariatric surgery 印度一项关于减肥手术后长期生活质量的多中心真实世界研究。
IF 2.2
Clinical Obesity Pub Date : 2024-07-25 DOI: 10.1111/cob.12693
Vivek Bindal, Priyanka Agarwal, Manish Khaitan, Arun Prasad, Atul N. C. Peters, Mahendra Narwaria, Randeep Wadhawan, Sumeet Shah, K. S. Kular, P. Praveen Raj, Aparna Govil Bhasker, Dhananjay Pandey, Shailesh Gupta, Naureen Mansuri, Dipali Dhagat, Harsha Jaithlia, Deeba Siddiqui, Beena Arora, Arya Singh
{"title":"An Indian multicentre real-world study on long-term quality of life outcomes following bariatric surgery","authors":"Vivek Bindal,&nbsp;Priyanka Agarwal,&nbsp;Manish Khaitan,&nbsp;Arun Prasad,&nbsp;Atul N. C. Peters,&nbsp;Mahendra Narwaria,&nbsp;Randeep Wadhawan,&nbsp;Sumeet Shah,&nbsp;K. S. Kular,&nbsp;P. Praveen Raj,&nbsp;Aparna Govil Bhasker,&nbsp;Dhananjay Pandey,&nbsp;Shailesh Gupta,&nbsp;Naureen Mansuri,&nbsp;Dipali Dhagat,&nbsp;Harsha Jaithlia,&nbsp;Deeba Siddiqui,&nbsp;Beena Arora,&nbsp;Arya Singh","doi":"10.1111/cob.12693","DOIUrl":"10.1111/cob.12693","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>The purpose of this study was to assess the impact of metabolic and bariatric surgery (MBS) on Quality of Life (QoL) in Indian patients with obesity over 10 years.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A retrospective chart review was conducted at 11 centres for individuals with MBS between February 2013 and May 2022. Patient medical records provided the source of de-identified data.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Data from 2132 individuals with a mean age of 43.28 ± 11.96 years was analysed. There were 37.43% men and 62.57% females in the study population. The study population had a mean preoperative body mass index (BMI) of 45.71 ± 10.38 kg/m<sup>2</sup>. The Bariatric Analysis and Reporting Outcome System (BAROS) scoring method showed a higher overall QoL score throughout all follow-up periods, with ‘very good’ outcomes at one, three and 7 years and ‘good’ outcomes at 5 and 10 years. Improvements in QoL were associated with a substantial improvement (<i>p</i> &lt; .01) in BMI at every follow-up time point.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Following MBS, individuals with obesity exhibited a substantial and long-term improvement in their overall QoL for up to 10 years. This study presents Indian data on QoL, which is considered one of the most important decision-making factors for or against an intervention.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"14 6","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cob.12693","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141757542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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