Clinical Neuroradiology最新文献_第7页

Thrombectomy Outcomes for Anterior Circulation Stroke in the 6-24 h Time Window Solely Based On NCCT and CTA: A Single Center Study. 仅根据 NCCT 和 CTA 在 6-24 小时时间窗内对前循环卒中进行血栓清除术的结果：单中心研究。

IF 2.8 3区医学

Clinical Neuroradiology Pub Date : 2025-03-01 Epub Date: 2024-10-01 DOI: 10.1007/s00062-024-01462-8

Dmytro Shchehlov, Stanislav Konotopchk, Valentyna Pankiv, Farida Rzayeva, Sergii Kolomiichenko, Mykola Vyval, Fabian Flottmann, Jens Fiehler, Anna A Kyselyova

{"title":"Thrombectomy Outcomes for Anterior Circulation Stroke in the 6-24 h Time Window Solely Based On NCCT and CTA: A Single Center Study.","authors":"Dmytro Shchehlov, Stanislav Konotopchk, Valentyna Pankiv, Farida Rzayeva, Sergii Kolomiichenko, Mykola Vyval, Fabian Flottmann, Jens Fiehler, Anna A Kyselyova","doi":"10.1007/s00062-024-01462-8","DOIUrl":"10.1007/s00062-024-01462-8","url":null,"abstract":"Purpose: Since perfusion imaging may be unavailable in smaller hospitals, alternative imaging selection methods for acute ischemic stroke can improve outcomes and optimize resources. This study assessed the safety and effectiveness of using imaging criteria other than DEFUSE 3 and DAWN for thrombectomy beyond 6 h from symptom onset in patients stroke in the anterior circulation.Methods: This is a retrospective, single-center analysis of consecutive patients with large vessel occlusion in the anterior circulation undergoing thrombectomy. Patients were categorized into two groups based on the collateral status (moderate collaterals and good collaterals).Results: Among 198 patients, 106 (54%) met the inclusion criteria and were analyzed. Good collateral status was observed in 78 (74%) patients. Patients with good collaterals showed significantly lower mRS scores at discharge and at 90 days compared to their counterparts with moderate collateral status (4 (3-4) vs. 4 (4-5); p = 0.001 and 2 (0-4) vs. 6 (3-6); p < 0.001, respectively). More patients with good collateral status achieved favorable outcomes at 90 days compared to those with moderate status (48 (61.5%) vs. 5 (17.9%); p < 0.001). Good collaterals were an independent predictor of good clinical outcomes at 90 days (OR = 1.31, 95% CI: 1.13-1.53, p < 0.001).Conclusion: Selecting patients for endovascular treatment of acute ischemic stroke using non-contrast CT and CT angiography shows 90-day outcomes similar to the DAWN and DEFUSE-3 trials. Using collateral status on CT angiography can predict favorable outcomes after mechanical thrombectomy in resource-limited settings where perfusion imaging is unavailable.","PeriodicalId":10391,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":"123-129"},"PeriodicalIF":2.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832689/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142342856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of an Image-based Classification Model to Identify Glioma Subtypes Using Arterial Spin Labeling Perfusion MRI On the Publicly Available UCSF Glioma Dataset. 在公开的加州大学旧金山分校胶质瘤数据集上评估使用动脉自旋标记灌注磁共振成像识别胶质瘤亚型的图像分类模型。

IF 2.8 3区医学

Clinical Neuroradiology Pub Date : 2025-03-01 Epub Date: 2024-10-17 DOI: 10.1007/s00062-024-01465-5

K Amador, H Kniep, J Fiehler, N D Forkert, T Lindner

{"title":"Evaluation of an Image-based Classification Model to Identify Glioma Subtypes Using Arterial Spin Labeling Perfusion MRI On the Publicly Available UCSF Glioma Dataset.","authors":"K Amador, H Kniep, J Fiehler, N D Forkert, T Lindner","doi":"10.1007/s00062-024-01465-5","DOIUrl":"10.1007/s00062-024-01465-5","url":null,"abstract":"Purpose: Glioma is a complex cancer comprising various subtypes and mutations, which may have different metabolic characteristics that can potentially be investigated and identified using perfusion imaging. Therefore, the aim of this work was to use radiomics and machine learning analysis of arterial spin labeling MRI data to automatically differentiate glioma subtypes and mutations.Methods: A total of 495 Arterial Spin Labeling (ASL) perfusion imaging datasets from the UCSF Glioma database were used in this study. These datasets were segmented to delineate the tumor volume and classified according to tumor grade, pathological diagnosis, and IDH status. Perfusion image data was obtained from a 3T MRI scanner using pseudo-continuous ASL. High level texture features were extracted for each ASL dataset using PyRadiomics after tumor volume segmentation and then analyzed using a machine learning framework consisting of ReliefF feature ranking and logistic model tree classification algorithms.Results: The results of the evaluation revealed balanced accuracies for the three endpoints ranging from 55.76% (SD = 4.28, 95% CI: 53.90-57.65) for the tumor grade using 25.4 ± 37.21 features, 62.53% (SD = 2.86, 95% CI: 61.27-63.78) for the mutation status with 23.3 ± 29.17 picked features, and 80.97% (SD = 1.83, 95% CI: 80.17-81.78) for the pathological diagnosis which used 47.3 ± 32.72 selected features.Conclusions: Radiomics and machine learning analysis of ASL perfusion data in glioma patients hold potential for aiding in the diagnosis and treatment of glioma, mainly for discerning glioblastoma from astrocytoma, while performance for tumor grading and mutation status appears limited.","PeriodicalId":10391,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":"151-158"},"PeriodicalIF":2.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142459549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Measurement of Healthy Adult Brain Temperature Using ¹H Magnetic Resonance Spectroscopy Thermometry. 利用 1H 磁共振波谱温度计测量健康成年人的脑温

IF 2.8 3区医学

Clinical Neuroradiology Pub Date : 2025-03-01 Epub Date: 2024-10-30 DOI: 10.1007/s00062-024-01467-3

Yahong Tan, Wenjia Liu, Yanhua Li, Nan Zhang, Mingxiao Wang, Shuo Sun, Lin Ma

{"title":"Measurement of Healthy Adult Brain Temperature Using 1H Magnetic Resonance Spectroscopy Thermometry.","authors":"Yahong Tan, Wenjia Liu, Yanhua Li, Nan Zhang, Mingxiao Wang, Shuo Sun, Lin Ma","doi":"10.1007/s00062-024-01467-3","DOIUrl":"10.1007/s00062-024-01467-3","url":null,"abstract":"Purpose: The purpose of this study is to measure the brain temperature (Tbr) by using 1H magnetic resonance spectroscopy (1H MRS) thermometry and investigate its age and gender differences in healthy adults. The brain temperature was further compared with the body temperature (Tbo) to investigate the possible existence of brain-body temperature gradient (∆T).Methods: A total of 80 subjects were included in this study. 1H MRS data were collected on a 3.0T MR scanner using Point Resolved Selective Spectroscopy (PRESS) sequence. Voxels were positioned in the right frontal (RF) lobe and left frontal (LF) lobe, respectively. The temperature of each voxel was calculated by chemical shift difference (∆δ) between H2O and NAA which was obtained by LCModel software. The average temperature of bilateral frontal lobe voxels was defined as Tbr for each subject. The average forehead temperature was acquired before MR scanning, defined as Tbo, in this study. The difference between Tbr and Tbo, denoted as the brain-body temperature gradient (∆T), was calculated. Age and gender characteristics of Tbr, ∆T and Tbo were analyzed.Results: Tbr (38.51 ± 0.59℃) was higher than Tbo (36.47 ± 0.26℃) (P < 0.05). Negative correlations were observed between Tbr and age (r = -0.49, P < 0.05) and between ∆T and age (r = -0.44, P < 0.05), whereas no correlation existed between Tbo and age (r = -0.03, P = 0.79).Conclusion: Our observation demonstrated that the brain temperature, derived from 1H MRS thermometry, is significantly higher than the body temperature, indicating the existence of a brain-body temperature gradient, and the brain temperature gradually decreases with age.","PeriodicalId":10391,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":"159-164"},"PeriodicalIF":2.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832680/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142544121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term Safety and Efficacy of the Derivo Embolization Device in a Single-center Series. 单中心系列研究中 Derivo 栓塞设备的长期安全性和有效性。

IF 2.8 3区医学

Clinical Neuroradiology Pub Date : 2024-12-01 Epub Date: 2024-05-30 DOI: 10.1007/s00062-024-01423-1

Lukas Goertz, David Zopfs, Jonathan Kottlors, Jan Borggrefe, Lenhard Pennig, Marc Schlamann, Christoph Kabbasch

{"title":"Long-term Safety and Efficacy of the Derivo Embolization Device in a Single-center Series.","authors":"Lukas Goertz, David Zopfs, Jonathan Kottlors, Jan Borggrefe, Lenhard Pennig, Marc Schlamann, Christoph Kabbasch","doi":"10.1007/s00062-024-01423-1","DOIUrl":"10.1007/s00062-024-01423-1","url":null,"abstract":"Purpose: This study analyzes the long-term clinical and angiographic outcomes of the Derivo Embolization Device (DED), an advanced flow diverter device with an electropolished surface, for the treatment of intracranial aneurysms.Methods: A consecutive series of 101 patients (mean age: 58 years, 72% female) treated with the DED for 122 aneurysms at a single center between 2017 and 2023 was retrospectively analyzed for major (change in National Institutes of Health Stroke Scale [NIHSS] score ≥ 4 points) and minor (change in NIHSS score < 4 points) neurological events, procedural morbidity (increase of at least one point on the modified Rankin Scale), and angiographic results.Results: There were 14 (11%) recurrent aneurysms, 15 (12%) ruptured aneurysms, 26 (21%) posterior circulation aneurysms and 16 (13%) fusiform or dissecting aneurysms. Device deployment failed in 1 case (1%). Procedure-related symptomatic procedural complications consisted of 2 (2%) major events (1 major stroke and 1 vessel perforation with intracranial hemorrhage and infarction) and 6 minor events (6 minor strokes). Procedural morbidity was 5%. There were no late ischemic or hemorrhagic events during follow-up. Complete and favorable aneurysm occlusion was achieved in 54% (40/74) and 62% (46/74) at a mean of 5 months, 71% (27/38) and 87% (33/38) at a mean of 12 months, and 76% (25/33) and 97% (32/33) at a mean of 35 months, respectively.Conclusion: The results demonstrate progressive aneurysm occlusion beyond 12 months after DED implantation with an almost 100% favorable occlusion rate. Procedural morbidity was low and there were no late complications.","PeriodicalId":10391,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":"789-798"},"PeriodicalIF":2.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11564379/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141174269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Propensity Score-matched Comparison of WEB 17 and WEB 21 with 4-7 mm Device Sizes for the Treatment of Unruptured Intracranial Aneurysms. 用于治疗未破裂颅内动脉瘤的 WEB 17 和 WEB 21 与 4-7 毫米装置尺寸的倾向得分匹配比较。

IF 2.8 3区医学

Clinical Neuroradiology Pub Date : 2024-12-01 Epub Date: 2024-06-19 DOI: 10.1007/s00062-024-01430-2

Lukas Goertz, Thomas Liebig, Eberhard Siebert, David Zopfs, Lenhard Pennig, Marc Schlamann, Alexandra Radomi, Franziska Dorn, Christoph Kabbasch

{"title":"Propensity Score-matched Comparison of WEB 17 and WEB 21 with 4-7 mm Device Sizes for the Treatment of Unruptured Intracranial Aneurysms.","authors":"Lukas Goertz, Thomas Liebig, Eberhard Siebert, David Zopfs, Lenhard Pennig, Marc Schlamann, Alexandra Radomi, Franziska Dorn, Christoph Kabbasch","doi":"10.1007/s00062-024-01430-2","DOIUrl":"10.1007/s00062-024-01430-2","url":null,"abstract":"Purpose: The WEB 17 system represents the fifth generation of Woven Endobridge (WEB) flow disruptors and features a low profile with fewer wires than its predecessor, the WEB 21. The present study compares the safety and efficacy of the WEB 17 and WEB 21 for the treatment of unruptured cerebral aneurysms with 4-7 mm device sizes, which were available for both systems.Methods: Patient and aneurysm characteristics, complications, clinical outcome and angiographic results were retrospectively analysed. 1:1 propensity score matching was performed to adjust for minor baseline differences between the groups.Results: Sixty aneurysms treated with WEB 21 and 90 with WEB 17 were included. The overall failure rate (deployment failure and adjunctive stent) was significantly higher with WEB 21 (16.7%) than with WEB 17 (3.3%, p < 0.01). The rates of neurological events between WEB 21 (6.7%) and WEB 17 treatment (1.1%) were not significantly different (p = 0.08). Also, procedural morbidity was comparably low in both groups (WEB 21: 3.3%, WEB 17: 0%, p = 0.16). The rates of complete/adequate occlusion at follow up were 69.7%/86.4% for WEB 17 vs. 80.4%/91.3% for WEB 21 at short-term (p = 0.27), and 64.5%/83.9% vs. 75.9%/86.2% at mid-term (p = 0.41), respectively. Propensity score matching confirmed the results of the unmatched series.Conclusion: WEB 17 and WEB 21 had a similar safety and efficacy profile, but WEB 17 was associated with an improved feasibility. Prospective studies with long-term follow-up will define the full potential of the WEB 17 system.","PeriodicalId":10391,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":"841-850"},"PeriodicalIF":2.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11564397/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141418195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Use of Hematoma Volume Based On Automated Segmentation of Chronic Subdural Hematoma Using 3D U-Net. 基于使用 3D U-Net 自动分割慢性硬膜下血肿的血肿体积临床应用。

IF 2.8 3区医学

Clinical Neuroradiology Pub Date : 2024-12-01 Epub Date: 2024-05-30 DOI: 10.1007/s00062-024-01428-w

Takayuki Inomata, Koji Nakaya, Mikio Matsuhiro, Jun Takei, Hiroto Shiozaki, Yasuto Noda

{"title":"Clinical Use of Hematoma Volume Based On Automated Segmentation of Chronic Subdural Hematoma Using 3D U-Net.","authors":"Takayuki Inomata, Koji Nakaya, Mikio Matsuhiro, Jun Takei, Hiroto Shiozaki, Yasuto Noda","doi":"10.1007/s00062-024-01428-w","DOIUrl":"10.1007/s00062-024-01428-w","url":null,"abstract":"Purpose: To propose a method for calculating hematoma volume based on automatic segmentation of chronic subdural hematoma (CSDH) using 3D U‑net and investigate whether it can be used clinically to predict recurrence.Methods: Hematoma volumes manually measured from pre- and postoperative computed tomography (CT) images were used as ground truth data to train 3D U‑net in 200 patients (400 CT scans). A total of 215 patients (430 CT scans) were used as test data to output segmentation results from the trained 3D U‑net model. The similarity with the ground truth data was evaluated using Dice scores for pre and postoperative separately. The recurrence prediction accuracy was evaluated by obtaining receiver operating characteristic (ROC) curves for the segmentation results. Using a typical mobile PC, the computation time per case was measured and the average time was calculated.Results: The median Dice score of the test data were preoperative hematoma volume (Pre-HV): 0.764 and postoperative subdural cavity volume (Post-SCV): 0.741. In ROC analyses assessing recurrence prediction, the area under the curve (AUC) of the manual was 0.755 in Pre-HV, whereas the 3D U‑net was 0.735. In Post-SCV, the manual AUC was 0.779; the 3D U‑net was 0.736. No significant differences were found between manual and 3D U‑net for all results. Using a mobile PC, the average time taken to output the test data results was 30 s per case.Conclusion: The proposed method is a simple, accurate, and clinically applicable; it can contribute to the widespread use of recurrence prediction scoring systems for CSDH.","PeriodicalId":10391,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":"799-807"},"PeriodicalIF":2.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141174290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Neonatal Cerebral Circulation Under Hypoxic Ischemic Risk Factors Based on Quantitative Analysis of Cerebral Veins with Magnetic Resonance Susceptibility Weighted Imaging. 基于磁共振感度加权成像脑静脉定量分析的缺氧缺血风险因素下的新生儿脑循环评估

IF 2.8 3区医学

Clinical Neuroradiology Pub Date : 2024-12-01 Epub Date: 2024-06-26 DOI: 10.1007/s00062-024-01432-0

Qi Xie, Yan-Hui Liao, Wen-Juan He, Peng-Peng Han, Jun Wu

{"title":"Evaluation of Neonatal Cerebral Circulation Under Hypoxic Ischemic Risk Factors Based on Quantitative Analysis of Cerebral Veins with Magnetic Resonance Susceptibility Weighted Imaging.","authors":"Qi Xie, Yan-Hui Liao, Wen-Juan He, Peng-Peng Han, Jun Wu","doi":"10.1007/s00062-024-01432-0","DOIUrl":"10.1007/s00062-024-01432-0","url":null,"abstract":"Purpose: To observe the regulation of cerebral circulation in vivo based on image segmentation algorithms for deep learning in medical imaging to automatically detect and quantify the neonatal deep medullary veins (DMVs) on susceptibility weighted imaging (SWI) images. To evaluate early cerebral circulation self-rescue for neonates undergoing risk of cerebral hypoxia-ischaemia in vivo.Methods: SWI images and clinical data of 317 neonates with or without risk of cerebral hypoxia-ischaemia were analyzed. Quantitative parameters showing the number, width, and curvature of DMVs were obtained using an image segmentation algorithm.Results: The number of DMVs was greater in males than in females (p < 0.01), and in term than in preterm infants (p = 0.001). The width of DMVs was greater in term than in preterm infants (p < 0.01), in low-risk than in high-risk group (p < 0.01), and in neonates without intracranial extracerebral haemorrhage (ICECH) than with ICECH (p < 0.05). The curvature of DMVs was greater in term than in preterm infants (P < 0.05). The width of both bilateral thalamic veins and anterior caudate nucleus veins were positively correlated with the number of DMVs; the width of bilateral thalamic veins was positively correlated with the width of DMVs.Conclusion: The DMVs quantification based on image segmentation algorithm may provide more detailed and stable quantitative information in neonate. SWI vein quantification may be an observable indicator for in vivo assessment of cerebral circulation self-regulation in neonatal hypoxic-ischemic brain injury.","PeriodicalId":10391,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":"859-869"},"PeriodicalIF":2.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11564194/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141449884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Subacute Degeneration of Fibers After Vertical Parasagittal Hemispherotomy. 垂直咽旁半球切除术后纤维的亚急性退化

IF 2.8 3区医学

Clinical Neuroradiology Pub Date : 2024-12-01 Epub Date: 2024-06-25 DOI: 10.1007/s00062-024-01427-x

Markus Hittinger, Till Hartlieb, Dieter Henrik Heiland, Pamela Heiland, Tom Pieper, Martin Staudt, Ansgar Berlis, Manfred Kudernatsch, Irina Mader

{"title":"Subacute Degeneration of Fibers After Vertical Parasagittal Hemispherotomy.","authors":"Markus Hittinger, Till Hartlieb, Dieter Henrik Heiland, Pamela Heiland, Tom Pieper, Martin Staudt, Ansgar Berlis, Manfred Kudernatsch, Irina Mader","doi":"10.1007/s00062-024-01427-x","DOIUrl":"10.1007/s00062-024-01427-x","url":null,"abstract":"Purpose: After vertical parasagittal hemispherotomy a restricted diffusion is often seen ipsilaterally and even distant from the adjacent resection margin. This retrospective cohort study analyses the anatomic site and the time course of the diffusion restriction after vertical parasagittal hemispherotomy.Methods: Fifty-nine patients were included into this study, all of them having had one pre-operative and at least one post-operative MRI, including diffusion imaging at b‑values of 0 and 1000 s/mm2 with a calculated ADC.Results: Diffusion restriction occurred exclusively on the operated site in all patients. In the basal ganglia, diffusion restriction was present in 37 of 38 patients at the first postoperative day with a duration of 38 days. In the midbrain, the posterior limb of the internal capsule and the thalamus, a restricted diffusion became postoperatively prominent at day 9 in all three localizations, with a duration of 36, 34 and 36 days, respectively. The incidence of thalamic lesions was lower if a preoperative damage had occurred.Conclusion: The restricted diffusion in the basal ganglia resembles direct effects of the operation at its edges, whereas the later appearing diffusion restriction in the midbrain and the posterior limb of the internal capsule rather belong to a degeneration of the descending fibers being transected by the hemispherotomy in the sense of a Wallerian degeneration. The presence of preoperative hemispheric lesions influences the development of diffusion restriction at subacute fiber degeneration.","PeriodicalId":10391,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":"851-858"},"PeriodicalIF":2.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11564309/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141449896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Radiomics Analysis of Quantitative Maps from Synthetic MRI for Predicting Grades and Molecular Subtypes of Diffuse Gliomas. 对合成磁共振成像定量图进行放射组学分析，以预测弥漫性胶质瘤的分级和分子亚型。

IF 2.8 3区医学

Clinical Neuroradiology Pub Date : 2024-12-01 Epub Date: 2024-06-10 DOI: 10.1007/s00062-024-01421-3

Danlin Lin, Jiehong Liu, Chao Ke, Haolin Chen, Jing Li, Yuanyao Xie, Jianhua Ma, Xiaofei Lv, Yanqiu Feng

{"title":"Radiomics Analysis of Quantitative Maps from Synthetic MRI for Predicting Grades and Molecular Subtypes of Diffuse Gliomas.","authors":"Danlin Lin, Jiehong Liu, Chao Ke, Haolin Chen, Jing Li, Yuanyao Xie, Jianhua Ma, Xiaofei Lv, Yanqiu Feng","doi":"10.1007/s00062-024-01421-3","DOIUrl":"10.1007/s00062-024-01421-3","url":null,"abstract":"Purpose: To investigate the feasibility of using radiomics analysis of quantitative maps from synthetic MRI to preoperatively predict diffuse glioma grades, isocitrate dehydrogenase (IDH) subtypes, and 1p/19q codeletion status.Methods: Data from 124 patients with diffuse glioma were used for analysis (n = 87 for training, n = 37 for testing). Quantitative T1, T2, and proton density (PD) maps were obtained using synthetic MRI. Enhancing tumour (ET), non-enhancing tumour and necrosis (NET), and peritumoral edema (PE) regions were segmented followed by manual fine-tuning. Features were extracted using PyRadiomics and then selected using Levene/T, BorutaShap and maximum relevance minimum redundancy algorithms. A support vector machine was adopted for classification. Receiver operating characteristic curve analysis and integrated discrimination improvement analysis were implemented to compare the performance of different radiomics models.Results: Radiomics models constructed using features from multiple tumour subregions (ET + NET + PE) in the combined maps (T1 + T2 + PD) achieved the highest AUC in all three prediction tasks, among which the AUC for differentiating lower-grade and high-grade diffuse gliomas, predicting IDH mutation status and predicting 1p/19q codeletion status were 0.92, 0.95 and 0.86 respectively. Compared with those constructed on individual T1, T2, and PD maps, the discriminant ability of radiomics models constructed on the combined maps separately increased by 11, 17 and 10% in predicting glioma grades, 35, 52 and 19% in predicting IDH mutation status, and 16, 15 and 14% in predicting 1p/19q codeletion status (p < 0.05).Conclusion: Radiomics analysis of quantitative maps from synthetic MRI provides a new quantitative imaging tool for the preoperative prediction of grades and molecular subtypes in diffuse gliomas.","PeriodicalId":10391,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":"817-826"},"PeriodicalIF":2.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141300201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endovascular Treatment of Large Core Infarcts: no Limits? 大面积核心梗塞的血管内治疗：无极限？

IF 2.8 3区医学

Clinical Neuroradiology Pub Date : 2024-12-01 Epub Date: 2024-11-14 DOI: 10.1007/s00062-024-01472-6

Martin Bendszus

引用次数: 0