Clinical NeuroradiologyPub Date : 2024-09-01Epub Date: 2024-03-15DOI: 10.1007/s00062-024-01395-2
Yingchun Wu, Feng Gao, Honglin Feng
{"title":"Hemodynamic Impairments of Evaluating Symptomatic Intracranial Atherosclerotic Stenosis using Quantitative Flow Ratio on Digital Subtraction Angiography : A Comparison with Computed Tomography Perfusion, MRI and Fractional Flow Reserve.","authors":"Yingchun Wu, Feng Gao, Honglin Feng","doi":"10.1007/s00062-024-01395-2","DOIUrl":"10.1007/s00062-024-01395-2","url":null,"abstract":"<p><strong>Purpose: </strong>Cerebral hemodynamics are important for the management of intracranial atherosclerotic stenosis (ICAS). The quantitative flow ratio (QFR) is a novel angiography-derived index for assessing the functional relevance of ICAS without pressure wires and adenosine. Good diagnostic yield with the hyperemic fractional flow reserve (FFR) have been reported, while data on the comparison of QFR to FFR are scarce.</p><p><strong>Methods: </strong>In this prospective study 56 patients with anterior circulation symptomatic ICAS who received endovascular treatment were included. The new method of computing QFR from a single angiographic view, i.e., the Murray law-based QFR (μQFR), was applied to the examined vessels. An artificial intelligence algorithm was developed to realize the automatic delineation of vascular contour. Pressure gradients were measured before and after treatment within the lesion vessel using a pressure guidewire and the FFR was calculated.</p><p><strong>Results: </strong>There was a good correlation between μQFR and FFR. Preoperative FFR predicted DWI watershed infarction (FFR optimal cut-off level: 0.755). Preoperative μQFR predicted DWI watershed infarction (μQFR optimal cut-off level: 0.51). Preoperative FFR predicted CTP hypoperfusion (FFR best predictive value: 0.62). Preoperative μQFR predicted CTP hypoperfusion (μQFR best predictive value: 0.375).</p><p><strong>Conclusion: </strong>The μQFR based on DSA images can be used as an indicator to assess the functional status of the lesion in patients with ICAS.</p>","PeriodicalId":10391,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":"613-624"},"PeriodicalIF":2.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140136578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical NeuroradiologyPub Date : 2024-09-01Epub Date: 2024-02-07DOI: 10.1007/s00062-024-01386-3
Marios-Nikos Psychogios, Nikos Ntoulias, Urs Fischer, Marc Luethi, Peter B Sporns
{"title":"Efficient Organization of a Stroke Center : Using Modern Communication Methods.","authors":"Marios-Nikos Psychogios, Nikos Ntoulias, Urs Fischer, Marc Luethi, Peter B Sporns","doi":"10.1007/s00062-024-01386-3","DOIUrl":"10.1007/s00062-024-01386-3","url":null,"abstract":"","PeriodicalId":10391,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":"731-733"},"PeriodicalIF":2.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139697068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical NeuroradiologyPub Date : 2024-09-01Epub Date: 2024-07-29DOI: 10.1007/s00062-024-01441-z
A Rau, M Schwabenland, R Watzlawick, M Prinz, H Urbach, D Erny, C A Taschner
{"title":"Freiburg Neuropathology Case Conference : Mild Disorientation and Mild Anomic Aphasia in a 79-Year-Old Female.","authors":"A Rau, M Schwabenland, R Watzlawick, M Prinz, H Urbach, D Erny, C A Taschner","doi":"10.1007/s00062-024-01441-z","DOIUrl":"10.1007/s00062-024-01441-z","url":null,"abstract":"","PeriodicalId":10391,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":"735-740"},"PeriodicalIF":2.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11339155/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141792087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Need of Fine-Tuned Radiology Aware Open-Source Large Language Models for Neuroradiology.","authors":"Partha Pratim Ray","doi":"10.1007/s00062-024-01454-8","DOIUrl":"https://doi.org/10.1007/s00062-024-01454-8","url":null,"abstract":"","PeriodicalId":10391,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141999507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical NeuroradiologyPub Date : 2024-06-01Epub Date: 2024-01-29DOI: 10.1007/s00062-024-01382-7
Anthony J Winder, Emma Am Stanley, Jens Fiehler, Nils D Forkert
{"title":"Challenges and Potential of Artificial Intelligence in Neuroradiology.","authors":"Anthony J Winder, Emma Am Stanley, Jens Fiehler, Nils D Forkert","doi":"10.1007/s00062-024-01382-7","DOIUrl":"10.1007/s00062-024-01382-7","url":null,"abstract":"<p><strong>Purpose: </strong>Artificial intelligence (AI) has emerged as a transformative force in medical research and is garnering increased attention in the public consciousness. This represents a critical time period in which medical researchers, healthcare providers, insurers, regulatory agencies, and patients are all developing and shaping their beliefs and policies regarding the use of AI in the healthcare sector. The successful deployment of AI will require support from all these groups. This commentary proposes that widespread support for medical AI must be driven by clear and transparent scientific reporting, beginning at the earliest stages of scientific research.</p><p><strong>Methods: </strong>A review of relevant guidelines and literature describing how scientific reporting plays a central role at key stages in the life cycle of an AI software product was conducted. To contextualize this principle within a specific medical domain, we discuss the current state of predictive tissue outcome modeling in acute ischemic stroke and the unique challenges presented therein.</p><p><strong>Results and conclusion: </strong>Translating AI methods from the research to the clinical domain is complicated by challenges related to model design and validation studies, medical product regulations, and healthcare providers' reservations regarding AI's efficacy and affordability. However, each of these limitations is also an opportunity for high-impact research that will help to accelerate the clinical adoption of state-of-the-art medical AI. In all cases, establishing and adhering to appropriate reporting standards is an important responsibility that is shared by all of the parties involved in the life cycle of a prospective AI software product.</p>","PeriodicalId":10391,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":"293-305"},"PeriodicalIF":2.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139569296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical NeuroradiologyPub Date : 2024-06-01Epub Date: 2024-02-28DOI: 10.1007/s00062-024-01394-3
Ying Wang, Bo Chen, Laixin Song, Yuzhe Li, Ming Xu, Tianxiang Huang, Feiyue Zeng
{"title":"Effect of Siphon Morphology on the Risk of C7 Segment Aneurysm Formation : A Case-control CFD Study.","authors":"Ying Wang, Bo Chen, Laixin Song, Yuzhe Li, Ming Xu, Tianxiang Huang, Feiyue Zeng","doi":"10.1007/s00062-024-01394-3","DOIUrl":"10.1007/s00062-024-01394-3","url":null,"abstract":"<p><strong>Purpose: </strong>Tortuosity of the internal carotid artery (ICA) is associated with intracranial aneurysms (IAs). The siphon is the most curved segment of the ICA, but its morphology has controversial effects on IAs. This study aimed to explore the morphometric features of the siphon and the potential hemodynamic mechanisms that may affect C7 aneurysm formation.</p><p><strong>Methods: </strong>In this study 32 patients with C7 aneurysms diagnosed at Xiangya Hospital between 2019 and 2021 and 32 control subjects were enrolled after propensity score matching. Computed tomography angiography (CTA) images were acquired to measure morphologic features, and then, by combining clinical data, simplified carotid siphon models were constructed, and computational fluid dynamics (CFD) analysis was performed.</p><p><strong>Results: </strong>The presence of C7 aneurysms was associated with the height of the C4-C6 curved arteries (odds ratio [OR] 0.028, 95% confidence interval [CI] 0.003-0.201; P < 0.001). The heights of the C4-C6 curved arteries in the aneurysm group were significantly shorter than those in the control group. The CFD analysis revealed that shorter C4-C6 bends led to greater blood velocity and pressure in the C7 segment arteries.</p><p><strong>Conclusion: </strong>A shorter C4-C6 bend was associated with distal C7 aneurysm formation, and an elaborate hemodynamic mechanism may underlie this association.</p>","PeriodicalId":10391,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":"485-494"},"PeriodicalIF":2.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11130050/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139982571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical NeuroradiologyPub Date : 2024-06-01Epub Date: 2024-05-16DOI: 10.1007/s00062-024-01425-z
Jens Fiehler, Matthias Bechstein
{"title":"Does Every Subdural Hematoma Patient Need an Embolization?","authors":"Jens Fiehler, Matthias Bechstein","doi":"10.1007/s00062-024-01425-z","DOIUrl":"10.1007/s00062-024-01425-z","url":null,"abstract":"","PeriodicalId":10391,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":"289-291"},"PeriodicalIF":2.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11130060/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140943720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical NeuroradiologyPub Date : 2024-06-01Epub Date: 2023-12-21DOI: 10.1007/s00062-023-01367-y
A Nikoghosyan, R Sciot, S A Jacobs, B F J Verhaaren
{"title":"Is Neuroradiology Complementary to Histopathology in Central Nervous System Tumors with an Alteration of the BCOR Gene?","authors":"A Nikoghosyan, R Sciot, S A Jacobs, B F J Verhaaren","doi":"10.1007/s00062-023-01367-y","DOIUrl":"10.1007/s00062-023-01367-y","url":null,"abstract":"","PeriodicalId":10391,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":"507-509"},"PeriodicalIF":2.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138828416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical NeuroradiologyPub Date : 2024-06-01Epub Date: 2024-05-16DOI: 10.1007/s00062-024-01419-x
M Frosch, A J Braun, J Grauvogel, M Prinz, H Urbach, D Erny, C A Taschner
{"title":"Freiburg Neuropathology Case Conference : A 54-Years-Old Patient with Fatigue, Headaches, and Personality Changes.","authors":"M Frosch, A J Braun, J Grauvogel, M Prinz, H Urbach, D Erny, C A Taschner","doi":"10.1007/s00062-024-01419-x","DOIUrl":"10.1007/s00062-024-01419-x","url":null,"abstract":"","PeriodicalId":10391,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":"515-521"},"PeriodicalIF":2.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11130063/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140944032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}