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OA-43 Multi-Center Phase II Trial of Iberdomide and SQ Daratamumab as Post-ASCT Maintenance Therapy in Pts with Multiple Myeloma (the IBEX Trial): Initial Safety Analysis and Interim Efficacy Results. 伊伯度胺和SQ达拉坦单抗作为多发性骨髓瘤患者asct后维持治疗的OA-43多中心II期试验（IBEX试验）：初步安全性分析和中期疗效结果
IF 4.1 4区 医学
Clinical Lymphoma, Myeloma & Leukemia Pub Date : 2026-09-01 Epub Date: 2026-09-22 DOI: 10.1016/S2152-2650(26)03344-6
Jeffrey A. Zonder, Andrew Kin, Craig Cole, Shiva Shrotriya, Marcella Kaddoura, Abhinav Deol, Malini Surapaneni, Attaya Suvannasankha, Amy Blake, Joseph Ellul, Kate Staub, Deborah Hackstock, Christy Houde, Erik Carr, Sarah Phillips, Julie Boerner, Hyejeong Jang, Seongho Kim
{"title":"OA-43 Multi-Center Phase II Trial of Iberdomide and SQ Daratamumab as Post-ASCT Maintenance Therapy in Pts with Multiple Myeloma (the IBEX Trial): Initial Safety Analysis and Interim Efficacy Results.","authors":"Jeffrey A. Zonder, Andrew Kin, Craig Cole, Shiva Shrotriya, Marcella Kaddoura, Abhinav Deol, Malini Surapaneni, Attaya Suvannasankha, Amy Blake, Joseph Ellul, Kate Staub, Deborah Hackstock, Christy Houde, Erik Carr, Sarah Phillips, Julie Boerner, Hyejeong Jang, Seongho Kim","doi":"10.1016/S2152-2650(26)03344-6","DOIUrl":"10.1016/S2152-2650(26)03344-6","url":null,"abstract":"","PeriodicalId":10348,"journal":{"name":"Clinical Lymphoma, Myeloma & Leukemia","volume":"26 ","pages":"Pages S28-S29"},"PeriodicalIF":4.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149010855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
OA-44 Multi-Omic Characterization of Teclistamab Resistance Reveals Diverse Evolutionary Trajectories in RRMM: Results From the RESISTEC Trial 耐药的OA-44多组学特征揭示了RRMM的不同进化轨迹：来自耐药试验的结果
IF 4.1 4区 医学
Clinical Lymphoma, Myeloma & Leukemia Pub Date : 2026-09-01 Epub Date: 2026-09-22 DOI: 10.1016/S2152-2650(26)03345-8
Tom Lesluyes, Céline Mazzotti, Chloé Cerutti, Laure Vincent, Pierre Feugier, Cyrille Hulin, Thomas Chalopin, Marie-Lorraine Chretien, Xavier Leleu, Lionel Karlin, Margaret Macro, Laurent Frenzel, Emilie Chalayer, Lydia Montes, Mohamad Mohty, Bertrand Arnulf, Titouan Cazaubiel, Luka Pavageau, Laure Derrier, Sabrina Maheo, Jill Corre
{"title":"OA-44 Multi-Omic Characterization of Teclistamab Resistance Reveals Diverse Evolutionary Trajectories in RRMM: Results From the RESISTEC Trial","authors":"Tom Lesluyes, Céline Mazzotti, Chloé Cerutti, Laure Vincent, Pierre Feugier, Cyrille Hulin, Thomas Chalopin, Marie-Lorraine Chretien, Xavier Leleu, Lionel Karlin, Margaret Macro, Laurent Frenzel, Emilie Chalayer, Lydia Montes, Mohamad Mohty, Bertrand Arnulf, Titouan Cazaubiel, Luka Pavageau, Laure Derrier, Sabrina Maheo, Jill Corre","doi":"10.1016/S2152-2650(26)03345-8","DOIUrl":"10.1016/S2152-2650(26)03345-8","url":null,"abstract":"","PeriodicalId":10348,"journal":{"name":"Clinical Lymphoma, Myeloma & Leukemia","volume":"26 ","pages":"Page S29"},"PeriodicalIF":4.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149010856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
OA-25 Evaluation of a Vision-Related Anamnestic Tool (VRAT) to Guide Belantamab Mafodotin Dosing With Bortezomib and Dexamethasone for Multiple Myeloma: Interim Results From the UKMRA ProMMise D Trial OA-25评估视力相关记忆工具（VRAT）指导贝兰他单抗马弗多汀与硼替佐米和地塞米松联合治疗多发性骨髓瘤：来自UKMRA承诺D试验的中期结果
IF 4.1 4区 医学
Clinical Lymphoma, Myeloma & Leukemia Pub Date : 2026-09-01 Epub Date: 2026-09-22 DOI: 10.1016/S2152-2650(26)03326-4
Rakesh Popat, Alexandra Welsh, Andrew Hall, Ceri Bygrave, Dean Smith, Simona Esposti, Frank Larkin, Gordon Cook, Matthew W. Jenner, Martin Kaiser, Lydia Lee, Sylvia Feyler, Anastascia Chew, Adam Forbes, Edward Belsham, Victoria Peacock, Izabelle Wood, Heena Patel, Laura Clayton, Sadie Roberts, Charlotte Pawlyn
{"title":"OA-25 Evaluation of a Vision-Related Anamnestic Tool (VRAT) to Guide Belantamab Mafodotin Dosing With Bortezomib and Dexamethasone for Multiple Myeloma: Interim Results From the UKMRA ProMMise D Trial","authors":"Rakesh Popat, Alexandra Welsh, Andrew Hall, Ceri Bygrave, Dean Smith, Simona Esposti, Frank Larkin, Gordon Cook, Matthew W. Jenner, Martin Kaiser, Lydia Lee, Sylvia Feyler, Anastascia Chew, Adam Forbes, Edward Belsham, Victoria Peacock, Izabelle Wood, Heena Patel, Laura Clayton, Sadie Roberts, Charlotte Pawlyn","doi":"10.1016/S2152-2650(26)03326-4","DOIUrl":"10.1016/S2152-2650(26)03326-4","url":null,"abstract":"","PeriodicalId":10348,"journal":{"name":"Clinical Lymphoma, Myeloma & Leukemia","volume":"26 ","pages":"Pages S16-S17"},"PeriodicalIF":4.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149010892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PA-021 ALKBH5-Mediated Regulation of XBP1 Impairs Plasma Cell Maturation and Confers Proteasome Inhibitor Resistance in Multiple Myeloma PA-021 alkbh5介导的XBP1调控损害了多发性骨髓瘤的浆细胞成熟并赋予蛋白酶体抑制剂耐药性
IF 4.1 4区 医学
Clinical Lymphoma, Myeloma & Leukemia Pub Date : 2026-09-01 Epub Date: 2026-09-22 DOI: 10.1016/S2152-2650(26)03392-6
Jianwei Qu, Yifan Hou, Zhen Cai
{"title":"PA-021 ALKBH5-Mediated Regulation of XBP1 Impairs Plasma Cell Maturation and Confers Proteasome Inhibitor Resistance in Multiple Myeloma","authors":"Jianwei Qu, Yifan Hou, Zhen Cai","doi":"10.1016/S2152-2650(26)03392-6","DOIUrl":"10.1016/S2152-2650(26)03392-6","url":null,"abstract":"","PeriodicalId":10348,"journal":{"name":"Clinical Lymphoma, Myeloma & Leukemia","volume":"26 ","pages":"Page S58"},"PeriodicalIF":4.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149010908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
OA-28 First-in-Human Phase Ia/Ib Study of QLS32015 (GPRC5D × CD3) in Patients (Pts) With Relapsed/Refractory Multiple Myeloma (RRMM): Updated Safety and Efficacy Data QLS32015 （GPRC5D × CD3）在复发/难治性多发性骨髓瘤（RRMM）患者（Pts）中的首次人体Ia/Ib期研究：最新的安全性和有效性数据
IF 4.1 4区 医学
Clinical Lymphoma, Myeloma & Leukemia Pub Date : 2026-09-01 Epub Date: 2026-09-22 DOI: 10.1016/S2152-2650(26)03329-X
Gang An, Baijun Fang, Xiaobing Huang, Yan Xu, Fei Li, Zhen Cai, XiaoJing Yan, Xianqi Feng, Wuping Li, Xiangmin Tong, Zengjun Li, Yuzhang Liu, Feifei Che, Bo Liu, Xinai Yang, Peng Shao, Hongying Wei, Qiong Wu, Lugui Qiu
{"title":"OA-28 First-in-Human Phase Ia/Ib Study of QLS32015 (GPRC5D × CD3) in Patients (Pts) With Relapsed/Refractory Multiple Myeloma (RRMM): Updated Safety and Efficacy Data","authors":"Gang An, Baijun Fang, Xiaobing Huang, Yan Xu, Fei Li, Zhen Cai, XiaoJing Yan, Xianqi Feng, Wuping Li, Xiangmin Tong, Zengjun Li, Yuzhang Liu, Feifei Che, Bo Liu, Xinai Yang, Peng Shao, Hongying Wei, Qiong Wu, Lugui Qiu","doi":"10.1016/S2152-2650(26)03329-X","DOIUrl":"10.1016/S2152-2650(26)03329-X","url":null,"abstract":"","PeriodicalId":10348,"journal":{"name":"Clinical Lymphoma, Myeloma & Leukemia","volume":"26 ","pages":"Pages S18-S19"},"PeriodicalIF":4.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149010982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PA-025 An Engineered Lysosomal Protease Inhibitor Improves CAR-T Cell Therapy in Multiple Myeloma by Preventing CAR Downmodulation and Inducing the Formation of Memory CAR-T Cells PA-025一种工程溶酶体蛋白酶抑制剂通过防止CAR下调和诱导记忆CAR- t细胞的形成来改善多发性骨髓瘤的CAR- t细胞治疗
IF 4.1 4区 医学
Clinical Lymphoma, Myeloma & Leukemia Pub Date : 2026-09-01 Epub Date: 2026-09-22 DOI: 10.1016/S2152-2650(26)03396-3
Fenghuang Zhan, Hongwei Xu, Yamin Meng, Zijun Zhang, Guido Tricot, Min Yang, David Mery, Majid Asgari, Sharmilan Thanendrarajan, Carolina Schinke, Maurizio Zangari, John Shaughnessy, Frits van Rhee, Yan Cheng
{"title":"PA-025 An Engineered Lysosomal Protease Inhibitor Improves CAR-T Cell Therapy in Multiple Myeloma by Preventing CAR Downmodulation and Inducing the Formation of Memory CAR-T Cells","authors":"Fenghuang Zhan, Hongwei Xu, Yamin Meng, Zijun Zhang, Guido Tricot, Min Yang, David Mery, Majid Asgari, Sharmilan Thanendrarajan, Carolina Schinke, Maurizio Zangari, John Shaughnessy, Frits van Rhee, Yan Cheng","doi":"10.1016/S2152-2650(26)03396-3","DOIUrl":"10.1016/S2152-2650(26)03396-3","url":null,"abstract":"","PeriodicalId":10348,"journal":{"name":"Clinical Lymphoma, Myeloma & Leukemia","volume":"26 ","pages":"Pages S60-S61"},"PeriodicalIF":4.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149010993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
OA-34 Interim Report of Phase I Results of a Phase I/II, Open Label Study to Evaluate Safety, Tolerability, and Efficacy of Elranatamab in Patients With Relapsed AL Amyloidosis 一项评估Elranatamab治疗复发性AL淀粉样变性患者的安全性、耐受性和有效性的I/II期开放标签研究的中期报告
IF 4.1 4区 医学
Clinical Lymphoma, Myeloma & Leukemia Pub Date : 2026-09-01 Epub Date: 2026-09-22 DOI: 10.1016/S2152-2650(26)03335-5
Giada Bianchi, Shahrier Hossain, Jacob P. Laubach, Shannon Miller, Adam Sperling, Pedro Vianna, Emily Simpson, Madison Chuma, Brendan Fink, Samantha Geberth, Emily Magnavita
{"title":"OA-34 Interim Report of Phase I Results of a Phase I/II, Open Label Study to Evaluate Safety, Tolerability, and Efficacy of Elranatamab in Patients With Relapsed AL Amyloidosis","authors":"Giada Bianchi, Shahrier Hossain, Jacob P. Laubach, Shannon Miller, Adam Sperling, Pedro Vianna, Emily Simpson, Madison Chuma, Brendan Fink, Samantha Geberth, Emily Magnavita","doi":"10.1016/S2152-2650(26)03335-5","DOIUrl":"10.1016/S2152-2650(26)03335-5","url":null,"abstract":"","PeriodicalId":10348,"journal":{"name":"Clinical Lymphoma, Myeloma & Leukemia","volume":"26 ","pages":"Pages S22-S23"},"PeriodicalIF":4.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149011039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PA-005 A multicenter real-world study: efficacy and outcomes of selinexor combined with pomalidomide and dexamethasone (XPd) in the treatment of multiple myeloma with central nervous system involvement 一项多中心现实世界研究：selinexor联合泊马度胺和地塞米松（XPd）治疗累及中枢神经系统的多发性骨髓瘤的疗效和结果
IF 4.1 4区 医学
Clinical Lymphoma, Myeloma & Leukemia Pub Date : 2026-09-01 Epub Date: 2026-09-22 DOI: 10.1016/S2152-2650(26)03376-8
JiaQi Wang, Yang Liu, Xuelin Dou, Lei Wen, Meilan Chen, Fang Wang, Aijun Liao, Xuewen Liu, Yizhe Qin, Jin Lu
{"title":"PA-005 A multicenter real-world study: efficacy and outcomes of selinexor combined with pomalidomide and dexamethasone (XPd) in the treatment of multiple myeloma with central nervous system involvement","authors":"JiaQi Wang, Yang Liu, Xuelin Dou, Lei Wen, Meilan Chen, Fang Wang, Aijun Liao, Xuewen Liu, Yizhe Qin, Jin Lu","doi":"10.1016/S2152-2650(26)03376-8","DOIUrl":"10.1016/S2152-2650(26)03376-8","url":null,"abstract":"","PeriodicalId":10348,"journal":{"name":"Clinical Lymphoma, Myeloma & Leukemia","volume":"26 ","pages":"Page S49"},"PeriodicalIF":4.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149011157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PA-014 A Scoring Model Based on 3D Telomere Profiling of Circulating Tumor Cells in the Peripheral Blood Predicts Relapse in Newly Diagnosed Multiple Myeloma Patients 基于外周血循环肿瘤细胞三维端粒谱的pa - 014a评分模型预测新诊断多发性骨髓瘤患者复发
IF 4.1 4区 医学
Clinical Lymphoma, Myeloma & Leukemia Pub Date : 2026-09-01 Epub Date: 2026-09-22 DOI: 10.1016/S2152-2650(26)03385-9
Yulia Shifrin, Zahabiya Husain, Hiren Dabhi, Sabine Mai, Svetlana Frenkel, Mary Cheang, Christine Liacos, Alexandra Papadimou, Meletios A. Dimopoulos, Efstathios Kastritis
{"title":"PA-014 A Scoring Model Based on 3D Telomere Profiling of Circulating Tumor Cells in the Peripheral Blood Predicts Relapse in Newly Diagnosed Multiple Myeloma Patients","authors":"Yulia Shifrin, Zahabiya Husain, Hiren Dabhi, Sabine Mai, Svetlana Frenkel, Mary Cheang, Christine Liacos, Alexandra Papadimou, Meletios A. Dimopoulos, Efstathios Kastritis","doi":"10.1016/S2152-2650(26)03385-9","DOIUrl":"10.1016/S2152-2650(26)03385-9","url":null,"abstract":"","PeriodicalId":10348,"journal":{"name":"Clinical Lymphoma, Myeloma & Leukemia","volume":"26 ","pages":"Page S54"},"PeriodicalIF":4.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149010788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
OA-24 Etentamig Combined With Pomalidomide Plus Dexamethasone (Pom+Dex) in Relapsed/Refractory Multiple Myeloma (RRMM) After 1–3 Prior Lines of Therapy: A Phase 1b Dose-Escalation and Safety Expansion Study OA-24依替坦米格联合泊马度胺+地塞米松（Pom+Dex）治疗复发/难治性多发性骨髓瘤（RRMM） 1-3个既往治疗线：1b期剂量递增和安全性扩展研究
IF 4.1 4区 医学
Clinical Lymphoma, Myeloma & Leukemia Pub Date : 2026-09-01 Epub Date: 2026-09-22 DOI: 10.1016/S2152-2650(26)03325-2
Cesar Rodriguez, Ariel Grajales-Cruz, Shonali Midha, Hang Quach, Matthew Pianko, Carrie Van Der Weyden, M. Hasib Sidiqi, Tomasz Wrobel, Michael Low, Claudio Cerchione, H. Miles Prince, Amandeep Godara, Jason Suh, Shane Lee, Akshanth R. Polepally, Sneha Rathi, Ross La Motte-Mohs, Lauren Heim, Hillary M. Peltier, Jovian Yu, Peter M. Voorhees
{"title":"OA-24 Etentamig Combined With Pomalidomide Plus Dexamethasone (Pom+Dex) in Relapsed/Refractory Multiple Myeloma (RRMM) After 1–3 Prior Lines of Therapy: A Phase 1b Dose-Escalation and Safety Expansion Study","authors":"Cesar Rodriguez, Ariel Grajales-Cruz, Shonali Midha, Hang Quach, Matthew Pianko, Carrie Van Der Weyden, M. Hasib Sidiqi, Tomasz Wrobel, Michael Low, Claudio Cerchione, H. Miles Prince, Amandeep Godara, Jason Suh, Shane Lee, Akshanth R. Polepally, Sneha Rathi, Ross La Motte-Mohs, Lauren Heim, Hillary M. Peltier, Jovian Yu, Peter M. Voorhees","doi":"10.1016/S2152-2650(26)03325-2","DOIUrl":"10.1016/S2152-2650(26)03325-2","url":null,"abstract":"","PeriodicalId":10348,"journal":{"name":"Clinical Lymphoma, Myeloma & Leukemia","volume":"26 ","pages":"Page S16"},"PeriodicalIF":4.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149010853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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