Clinical Lymphoma, Myeloma & Leukemia最新文献
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TRIgnite- 1Study, Phase 1, First-in-Human Study of ISB 2001: A BCMAxCD38xCD3-Targeting Trispecific Antibody for Patients with Relapsed/Refractory Multiple Myeloma (RRMM)—Dose Escalation (DE) Results
TRIgnite- 1研究，i期，ISB 2001的首次人体研究：针对复发/难治性多发性骨髓瘤（RRMM）患者的bcmaxcd38xcd3靶向三特异性抗体-剂量递增（DE）结果
IF 2.7
4区 医学
Hang Quach, Bradley Augustson, David Levitz, Hanlon Sia, Eben Lichtman, Nicole Wong Doo, Michaela Liedtke, Camille Martinet, Vinu Menon, Andrew Garton, Cyril Konto, Lida Pacaud, Beata Holkova, Amit Khot
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{"title":"TRIgnite- 1Study, Phase 1, First-in-Human Study of ISB 2001: A BCMAxCD38xCD3-Targeting Trispecific Antibody for Patients with Relapsed/Refractory Multiple Myeloma (RRMM)—Dose Escalation (DE) Results","authors":"Hang Quach, Bradley Augustson, David Levitz, Hanlon Sia, Eben Lichtman, Nicole Wong Doo, Michaela Liedtke, Camille Martinet, Vinu Menon, Andrew Garton, Cyril Konto, Lida Pacaud, Beata Holkova, Amit Khot","doi":"10.1016/S2152-2650(25)03439-1","DOIUrl":"10.1016/S2152-2650(25)03439-1","url":null,"abstract":"","PeriodicalId":10348,"journal":{"name":"Clinical Lymphoma, Myeloma & Leukemia","volume":"25 ","pages":"Pages S23-S24"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145094608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Non-linear Impact of BMI on Anti-BCMA CAR-T Outcomes: Overweight Paradox in Myeloma
BMI对抗bcma CAR-T结果的非线性影响：骨髓瘤的超重悖论
IF 2.7
4区 医学
Ruth Choa, Kevin Miller, Advait Joshi, Cole Minsky, Samuel Han, Alexis Barselau, Andrew Yee, Andrew Branagan, Benjamin Puliafito, Matthew Frigault, Noopur Raje, Diana Cirstea
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{"title":"Non-linear Impact of BMI on Anti-BCMA CAR-T Outcomes: Overweight Paradox in Myeloma","authors":"Ruth Choa, Kevin Miller, Advait Joshi, Cole Minsky, Samuel Han, Alexis Barselau, Andrew Yee, Andrew Branagan, Benjamin Puliafito, Matthew Frigault, Noopur Raje, Diana Cirstea","doi":"10.1016/S2152-2650(25)03482-2","DOIUrl":"10.1016/S2152-2650(25)03482-2","url":null,"abstract":"","PeriodicalId":10348,"journal":{"name":"Clinical Lymphoma, Myeloma & Leukemia","volume":"25 ","pages":"Pages S52-S53"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145095374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Economic Value of Tocilizumab Prophylaxis to Prevent Cytokine Release Syndrome (CRS) during Outpatient Teclistamab (Tec) or Talquetamab (Tal) Initiation for Relapsed/Refractory Multiple Myeloma (RRMM)
托珠单抗预防复发/难治性多发性骨髓瘤（RRMM）患者在门诊接受替司他单抗（Tec）或塔克他单抗（Tal）治疗期间细胞因子释放综合征（CRS）的经济价值
IF 2.7
4区 医学
Amir Ali, Arveen Kaur, Felice Yang, Yi-Hsuan Liu, Joseph Goble, Xinke Zhang, Niodita Gupta-Werner, Tonya Le Blanc, Saurabh Patel, Arielle Bensimon, Ariel Grajales-Cruz
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{"title":"Economic Value of Tocilizumab Prophylaxis to Prevent Cytokine Release Syndrome (CRS) during Outpatient Teclistamab (Tec) or Talquetamab (Tal) Initiation for Relapsed/Refractory Multiple Myeloma (RRMM)","authors":"Amir Ali, Arveen Kaur, Felice Yang, Yi-Hsuan Liu, Joseph Goble, Xinke Zhang, Niodita Gupta-Werner, Tonya Le Blanc, Saurabh Patel, Arielle Bensimon, Ariel Grajales-Cruz","doi":"10.1016/S2152-2650(25)03475-5","DOIUrl":"10.1016/S2152-2650(25)03475-5","url":null,"abstract":"","PeriodicalId":10348,"journal":{"name":"Clinical Lymphoma, Myeloma & Leukemia","volume":"25 ","pages":"Page S48"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145094611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Novel NKp30-Directed Bispecific Natural Killer Cell Engagers Targeting GPRC5D or CD38 for the Treatment of Multiple Myeloma
针对GPRC5D或CD38的新型nkp30定向双特异性自然杀伤细胞接合物治疗多发性骨髓瘤
IF 2.7
4区 医学
Dorothee Winterberg, Svenja Andreas, Carina Gehlert, Steffen Krohn, Matthias Peipp, Katja Klausz
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{"title":"Novel NKp30-Directed Bispecific Natural Killer Cell Engagers Targeting GPRC5D or CD38 for the Treatment of Multiple Myeloma","authors":"Dorothee Winterberg, Svenja Andreas, Carina Gehlert, Steffen Krohn, Matthias Peipp, Katja Klausz","doi":"10.1016/S2152-2650(25)03441-X","DOIUrl":"10.1016/S2152-2650(25)03441-X","url":null,"abstract":"","PeriodicalId":10348,"journal":{"name":"Clinical Lymphoma, Myeloma & Leukemia","volume":"25 ","pages":"Page S25"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145098196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Cover Page
封面页
IF 2.7
4区 医学
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{"title":"Cover Page","authors":"","doi":"10.1016/S2152-2650(25)03401-9","DOIUrl":"10.1016/S2152-2650(25)03401-9","url":null,"abstract":"","PeriodicalId":10348,"journal":{"name":"Clinical Lymphoma, Myeloma & Leukemia","volume":"25 ","pages":"Page i"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145098198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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TET2 and EZH2 Genetic Alterations Promote Malignant CAR-T Transformation in Anti-BCMA CAR-T Therapy
抗bcma CAR-T治疗中TET2和EZH2基因改变促进恶性CAR-T转化
IF 2.7
4区 医学
Adolfo Aleman PhD, Rudra Prusad Dutta PhD, Oliver Van Oekelen MD, PhD, David Melnekoff PhD, Tarek Mouhieddine MD, Leah Grossman MS, Shriya Desai BS, Sidorela Reci BA, Patrick Brunner MD, Alessandro Lagana PhD, Sundar Jagannath MBBS, Joshua Brody MD, Samir Parekh MD, MBBS
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{"title":"TET2 and EZH2 Genetic Alterations Promote Malignant CAR-T Transformation in Anti-BCMA CAR-T Therapy","authors":"Adolfo Aleman PhD, Rudra Prusad Dutta PhD, Oliver Van Oekelen MD, PhD, David Melnekoff PhD, Tarek Mouhieddine MD, Leah Grossman MS, Shriya Desai BS, Sidorela Reci BA, Patrick Brunner MD, Alessandro Lagana PhD, Sundar Jagannath MBBS, Joshua Brody MD, Samir Parekh MD, MBBS","doi":"10.1016/S2152-2650(25)03405-6","DOIUrl":"10.1016/S2152-2650(25)03405-6","url":null,"abstract":"","PeriodicalId":10348,"journal":{"name":"Clinical Lymphoma, Myeloma & Leukemia","volume":"25 ","pages":"Page S1"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145098202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Rapid Peak CAR-T Expansion is Associated with Delayed Neurotoxicity Following Ciltacabtagene Autoleucel in Multiple Myeloma
快速峰值CAR-T扩增与迟发性神经毒性在多发性骨髓瘤西他他烯自体醇治疗相关
IF 2.7
4区 医学
Hitomi Hosoya, Arash Velayati, Danai Dima, Alexandria Jensen, Andrew Portuguese, Vanna Hovanky, Lekha Mikkilineni, Lauren Peres, Sylvester Homsy, Masooma S. Rana, Juancarlos Cancilla, Zachary Ehlinger, Bita Sahaf, Theresa Latchford, Ciara Freeman, Omar Castaneda Puglianini, Saurabh Dahiya, Frederick Locke, David Miklos, Rahul Banerjee, Surbhi Sidana
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{"title":"Rapid Peak CAR-T Expansion is Associated with Delayed Neurotoxicity Following Ciltacabtagene Autoleucel in Multiple Myeloma","authors":"Hitomi Hosoya, Arash Velayati, Danai Dima, Alexandria Jensen, Andrew Portuguese, Vanna Hovanky, Lekha Mikkilineni, Lauren Peres, Sylvester Homsy, Masooma S. Rana, Juancarlos Cancilla, Zachary Ehlinger, Bita Sahaf, Theresa Latchford, Ciara Freeman, Omar Castaneda Puglianini, Saurabh Dahiya, Frederick Locke, David Miklos, Rahul Banerjee, Surbhi Sidana","doi":"10.1016/S2152-2650(25)03409-3","DOIUrl":"10.1016/S2152-2650(25)03409-3","url":null,"abstract":"","PeriodicalId":10348,"journal":{"name":"Clinical Lymphoma, Myeloma & Leukemia","volume":"25 ","pages":"Page S4"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145098205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Updated Efficacy and Safety Results of Subcutaneous Daratumumab Plus Lenalidomide Versus Lenalidomide Alone as Maintenance Therapy in Newly Diagnosed Multiple Myeloma After Transplant: AURIGA Study
皮下达拉单抗联合来那度胺与单独来那度胺作为移植后新诊断多发性骨髓瘤维持治疗的最新疗效和安全性结果：AURIGA研究
IF 2.7
4区 医学
Larry Anderson, Alfred Chung, Laahn Foster, Chakra Chaulagain, Erin Pettijohn, Andrew Cowan, Caitlin Costello, Sarah Larson, Douglas Sborov, Kenneth Shain, Rebecca Silbermann, Peter Voorhees, Robert Rifkin, Maria Krevvata, Mai Ngo, Sharmila Patel, Vipin Khare, Annelore Cortoos, Robin Carson, Thomas Lin, Ashraf Badros
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{"title":"Updated Efficacy and Safety Results of Subcutaneous Daratumumab Plus Lenalidomide Versus Lenalidomide Alone as Maintenance Therapy in Newly Diagnosed Multiple Myeloma After Transplant: AURIGA Study","authors":"Larry Anderson, Alfred Chung, Laahn Foster, Chakra Chaulagain, Erin Pettijohn, Andrew Cowan, Caitlin Costello, Sarah Larson, Douglas Sborov, Kenneth Shain, Rebecca Silbermann, Peter Voorhees, Robert Rifkin, Maria Krevvata, Mai Ngo, Sharmila Patel, Vipin Khare, Annelore Cortoos, Robin Carson, Thomas Lin, Ashraf Badros","doi":"10.1016/S2152-2650(25)03451-2","DOIUrl":"10.1016/S2152-2650(25)03451-2","url":null,"abstract":"","PeriodicalId":10348,"journal":{"name":"Clinical Lymphoma, Myeloma & Leukemia","volume":"25 ","pages":"Pages S31-S32"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145098544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Clonotypic B Cells are Passengers During Malignant Transformation and not Drivers of Disease Progression in Plasma Cell (PC) Neoplasms
克隆型B细胞是浆细胞（PC）肿瘤恶性转化过程中的过客，而不是疾病进展的驱动因素
IF 2.7
4区 医学
Carmen Gonzalez, Camila Guerrero, Juan-Jose Garces, Alejandro Medina, Noemi Puig, Maria-Teresa Cedena, Diego Alignani, Sarai Sarvide, Paula Aguirre, Jose-Maria Lamo-Espinosa, Ramon Lecumberri, Felipe Prosper, Paula Rodríguez-Otero, Jose-Angel Martinez-Climent, Mario Nuvolone, Giovanni Palladini, Laura Rosiñol, Ramon Garcia-Sanz, Joaquin Martinez-Lopez, María-Victoria Mateos, Bruno Paiva
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{"title":"Clonotypic B Cells are Passengers During Malignant Transformation and not Drivers of Disease Progression in Plasma Cell (PC) Neoplasms","authors":"Carmen Gonzalez, Camila Guerrero, Juan-Jose Garces, Alejandro Medina, Noemi Puig, Maria-Teresa Cedena, Diego Alignani, Sarai Sarvide, Paula Aguirre, Jose-Maria Lamo-Espinosa, Ramon Lecumberri, Felipe Prosper, Paula Rodríguez-Otero, Jose-Angel Martinez-Climent, Mario Nuvolone, Giovanni Palladini, Laura Rosiñol, Ramon Garcia-Sanz, Joaquin Martinez-Lopez, María-Victoria Mateos, Bruno Paiva","doi":"10.1016/S2152-2650(25)03446-9","DOIUrl":"10.1016/S2152-2650(25)03446-9","url":null,"abstract":"","PeriodicalId":10348,"journal":{"name":"Clinical Lymphoma, Myeloma & Leukemia","volume":"25 ","pages":"Page S28"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145098603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Outpatient Step-Up Dosing of Teclistamab (TEC): An Implementation Process Shifting from the Academic Inpatient (IP) to Community Outpatient (OP) Setting
门诊增加Teclistamab剂量（TEC）：从学术住院（IP）到社区门诊（OP）设置的实施过程
IF 2.7
4区 医学
Christine Chen, HIlary Weatherby, Esther Masih-Khan, Jessica Lois, Rina Jeong, Eva Lee, Laura Olmi, Yasmin Daniel, Lia Norrie, Marina Riccio, Celina Dara, Kayee Tung, Sita Bhella, Vishal Kukreti, Guido Lancman, Suzanne Trudel, Chloe Yang, A. Keith Stewart
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{"title":"Outpatient Step-Up Dosing of Teclistamab (TEC): An Implementation Process Shifting from the Academic Inpatient (IP) to Community Outpatient (OP) Setting","authors":"Christine Chen, HIlary Weatherby, Esther Masih-Khan, Jessica Lois, Rina Jeong, Eva Lee, Laura Olmi, Yasmin Daniel, Lia Norrie, Marina Riccio, Celina Dara, Kayee Tung, Sita Bhella, Vishal Kukreti, Guido Lancman, Suzanne Trudel, Chloe Yang, A. Keith Stewart","doi":"10.1016/S2152-2650(25)03481-0","DOIUrl":"10.1016/S2152-2650(25)03481-0","url":null,"abstract":"","PeriodicalId":10348,"journal":{"name":"Clinical Lymphoma, Myeloma & Leukemia","volume":"25 ","pages":"Page S52"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145098617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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