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Clinical Lymphoma, Myeloma & Leukemia最新文献

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Real-World Long-Term Effectiveness and Safety Outcomes Among Patients Receiving Teclistamab for the Treatment of Relapsed/Refractory Multiple Myeloma (RRMM) 接受特司他抗治疗复发/难治性多发性骨髓瘤（RRMM）患者的长期疗效和安全性
IF 2.7 4区 医学
Clinical Lymphoma, Myeloma & Leukemia Pub Date : 2025-09-01 DOI: 10.1016/S2152-2650(25)03489-5
Carlyn Rose Tan, Tala Shekarkhand, David Nemirovsky, Andriy Derkach, Kylee MacLachlan, Malin Hultcrantz, Hani Hassoun, Sham Mailankody, Urvi Shah, Sridevi Rajeeve, Hamza Hashmi, Gunjan Shah, Michael Scordo, Heather Landau, Sergio Giralt, Alexander Lesokhin, Neha Korde, Francesco Maura, Maximilian Merz, Gilbert Ko, Saad Usmani
{"title":"Real-World Long-Term Effectiveness and Safety Outcomes Among Patients Receiving Teclistamab for the Treatment of Relapsed/Refractory Multiple Myeloma (RRMM)","authors":"Carlyn Rose Tan, Tala Shekarkhand, David Nemirovsky, Andriy Derkach, Kylee MacLachlan, Malin Hultcrantz, Hani Hassoun, Sham Mailankody, Urvi Shah, Sridevi Rajeeve, Hamza Hashmi, Gunjan Shah, Michael Scordo, Heather Landau, Sergio Giralt, Alexander Lesokhin, Neha Korde, Francesco Maura, Maximilian Merz, Gilbert Ko, Saad Usmani","doi":"10.1016/S2152-2650(25)03489-5","DOIUrl":"10.1016/S2152-2650(25)03489-5","url":null,"abstract":"","PeriodicalId":10348,"journal":{"name":"Clinical Lymphoma, Myeloma & Leukemia","volume":"25 ","pages":"Pages S56-S57"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145099104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative Analysis of Four NGS Protocols for Measurable Residual Disease Assessment Testing ctDNA and Bone Marrow Samples in Multiple Myeloma 多发性骨髓瘤中ctDNA和骨髓样本可测量残留疾病评估的四种NGS方案的比较分析
IF 2.7 4区 医学
Clinical Lymphoma, Myeloma & Leukemia Pub Date : 2025-09-01 DOI: 10.1016/S2152-2650(25)03426-3
Silvia Armuzzi, Anke Schilhabel, Barbara Taurisano, Marina Martello, Ilaria Vigliotta, Vincenza Solli, Ignazia Pistis, Enrica Borsi, Viola Meixian Vuong, Alessia Croce, Alessia Varacalli, Andrea Poletti, Monika Brüggemann, Elena Zamagni, Carolina Terragna
{"title":"Comparative Analysis of Four NGS Protocols for Measurable Residual Disease Assessment Testing ctDNA and Bone Marrow Samples in Multiple Myeloma","authors":"Silvia Armuzzi, Anke Schilhabel, Barbara Taurisano, Marina Martello, Ilaria Vigliotta, Vincenza Solli, Ignazia Pistis, Enrica Borsi, Viola Meixian Vuong, Alessia Croce, Alessia Varacalli, Andrea Poletti, Monika Brüggemann, Elena Zamagni, Carolina Terragna","doi":"10.1016/S2152-2650(25)03426-3","DOIUrl":"10.1016/S2152-2650(25)03426-3","url":null,"abstract":"","PeriodicalId":10348,"journal":{"name":"Clinical Lymphoma, Myeloma & Leukemia","volume":"25 ","pages":"Page S15"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145095082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Isatuximab Subcutaneous via an on-body Delivery System versus Isatuximab Intravenous, Plus Pomalidomide and Dexamethasone, in Relapsed/Refractory Multiple Myeloma: The Randomized Phase 3 IRAKLIA Study 依沙妥昔单抗皮下给药与依沙妥昔单抗静脉注射加泊马度胺和地塞米松治疗复发/难治性多发性骨髓瘤：随机3期IRAKLIA研究
IF 2.7 4区 医学
Clinical Lymphoma, Myeloma & Leukemia Pub Date : 2025-09-01 DOI: 10.1016/S2152-2650(25)03462-7
Sikander Ailawadhi, Ivan Špička, Jin Lu, Albert Oriol, Silvia Ling, Fredrik Schjesvold, Alejandro Berkovits, Marek Hus, Meletios Dimopoulos, Sevgi Kalayoğlu Beşışık, Péter Rajnics, Vania Hungria, Maria del Rosario Custidiano, Gurdeep Parmar, Xavier Leleu, Claudio Cerchione, Tondre T. Buck, Jiří Minařík, Rick Zhang, Dorothée Sémiond, Philippe Moreau
{"title":"Isatuximab Subcutaneous via an on-body Delivery System versus Isatuximab Intravenous, Plus Pomalidomide and Dexamethasone, in Relapsed/Refractory Multiple Myeloma: The Randomized Phase 3 IRAKLIA Study","authors":"Sikander Ailawadhi, Ivan Špička, Jin Lu, Albert Oriol, Silvia Ling, Fredrik Schjesvold, Alejandro Berkovits, Marek Hus, Meletios Dimopoulos, Sevgi Kalayoğlu Beşışık, Péter Rajnics, Vania Hungria, Maria del Rosario Custidiano, Gurdeep Parmar, Xavier Leleu, Claudio Cerchione, Tondre T. Buck, Jiří Minařík, Rick Zhang, Dorothée Sémiond, Philippe Moreau","doi":"10.1016/S2152-2650(25)03462-7","DOIUrl":"10.1016/S2152-2650(25)03462-7","url":null,"abstract":"","PeriodicalId":10348,"journal":{"name":"Clinical Lymphoma, Myeloma & Leukemia","volume":"25 ","pages":"Pages S39-S40"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145095173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acquired FCRL5 Mutation Leading to Cevostamab Resistance in Multiple Myeloma 获得性FCRL5突变导致多发性骨髓瘤患者对头孢司他抗耐药
IF 2.7 4区 医学
Clinical Lymphoma, Myeloma & Leukemia Pub Date : 2025-09-01 DOI: 10.1016/S2152-2650(25)03476-7
Cecilia Bonolo de Campos, David Scott, Mariano Arribas, Esther Masih-Khan, Laura Bruins, Ding Yan Wang, Zhihua Li, Safa Abdulsalam, Greg Ahmann, Shaji Kumar, Esteban Braggio, Trevor Pugh, Rafael Fonseca, Suzanne Trudel, A. Keith Stewart
{"title":"Acquired FCRL5 Mutation Leading to Cevostamab Resistance in Multiple Myeloma","authors":"Cecilia Bonolo de Campos, David Scott, Mariano Arribas, Esther Masih-Khan, Laura Bruins, Ding Yan Wang, Zhihua Li, Safa Abdulsalam, Greg Ahmann, Shaji Kumar, Esteban Braggio, Trevor Pugh, Rafael Fonseca, Suzanne Trudel, A. Keith Stewart","doi":"10.1016/S2152-2650(25)03476-7","DOIUrl":"10.1016/S2152-2650(25)03476-7","url":null,"abstract":"","PeriodicalId":10348,"journal":{"name":"Clinical Lymphoma, Myeloma & Leukemia","volume":"25 ","pages":"Page S49"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145098177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bone Marrow-Homing and Chimeric Antigen Receptor-Engineered Lipid Nanoparticles Enable Sequential miRNA Delivery for Precision Therapy of Multiple Myeloma 骨髓归巢和嵌合抗原受体工程脂质纳米颗粒使序列miRNA递送用于多发性骨髓瘤的精确治疗
IF 2.7 4区 医学
Clinical Lymphoma, Myeloma & Leukemia Pub Date : 2025-09-01 DOI: 10.1016/S2152-2650(25)03440-8
Huaqing Jing, Junke Guo, Yonghuan Wang, Xiaoyu Zhang, Xiyue Sun, Yijie Wang, Lugui Qiu, Mu Hao
{"title":"Bone Marrow-Homing and Chimeric Antigen Receptor-Engineered Lipid Nanoparticles Enable Sequential miRNA Delivery for Precision Therapy of Multiple Myeloma","authors":"Huaqing Jing, Junke Guo, Yonghuan Wang, Xiaoyu Zhang, Xiyue Sun, Yijie Wang, Lugui Qiu, Mu Hao","doi":"10.1016/S2152-2650(25)03440-8","DOIUrl":"10.1016/S2152-2650(25)03440-8","url":null,"abstract":"","PeriodicalId":10348,"journal":{"name":"Clinical Lymphoma, Myeloma & Leukemia","volume":"25 ","pages":"Pages S24-S25"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145098195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Final Analysis of the GEM-BELA-VRd Phase II Trial: Belantamab Mafodotin Plus VRd in Newly Diagnosed Transplant-Eligible Myeloma After 2 Years of Maintenance with Belantamab and Lenalidomide GEM-BELA-VRd II期试验的最终分析：贝兰他单抗和来那度胺维持2年后，贝兰他单抗+ VRd治疗新诊断的适合移植的骨髓瘤
IF 2.7 4区 医学
Clinical Lymphoma, Myeloma & Leukemia Pub Date : 2025-09-01 DOI: 10.1016/S2152-2650(25)03452-4
Verónica González-Calle, Noemi Puig, Enrique Ocio, Javier de la Rubia, Paula Rodríguez-Otero, Borja Puertas, Felipe de Arriba, Valentin Cabañas, Esther Gonzalez Garcia, Cristina Encinas, Alexia Suarez-Cabrera, Joan Bargay, Joaquin Martinez-Lopez, Sonia González-Pérez, Jose Angel Hernandez Rivas, Laura Rosiñol, Beatriz Rey Búa, Miguel Teodoro Hernandez, Rafael Alonso Fernandez, Bruno Paiva, María-Victoria Mateos
{"title":"Final Analysis of the GEM-BELA-VRd Phase II Trial: Belantamab Mafodotin Plus VRd in Newly Diagnosed Transplant-Eligible Myeloma After 2 Years of Maintenance with Belantamab and Lenalidomide","authors":"Verónica González-Calle, Noemi Puig, Enrique Ocio, Javier de la Rubia, Paula Rodríguez-Otero, Borja Puertas, Felipe de Arriba, Valentin Cabañas, Esther Gonzalez Garcia, Cristina Encinas, Alexia Suarez-Cabrera, Joan Bargay, Joaquin Martinez-Lopez, Sonia González-Pérez, Jose Angel Hernandez Rivas, Laura Rosiñol, Beatriz Rey Búa, Miguel Teodoro Hernandez, Rafael Alonso Fernandez, Bruno Paiva, María-Victoria Mateos","doi":"10.1016/S2152-2650(25)03452-4","DOIUrl":"10.1016/S2152-2650(25)03452-4","url":null,"abstract":"","PeriodicalId":10348,"journal":{"name":"Clinical Lymphoma, Myeloma & Leukemia","volume":"25 ","pages":"Pages S32-S33"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145098209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Midnolin Downregulation Promotes Myelomagenesis via Impacting Ubiquitination Independent Pathway of Protein Degradation Midnolin下调通过影响泛素化非依赖性蛋白降解途径促进骨髓瘤形成
IF 2.7 4区 医学
Clinical Lymphoma, Myeloma & Leukemia Pub Date : 2025-09-01 DOI: 10.1016/S2152-2650(25)03432-9
Anna Besschetnova, Francesco Ladisa, Anais Schavgoulidze, Shuhui Deng, Jessica Fong Ng, Eugenio Morelli, Mehmet Samur, Christopher Nardone, Xin Gu, Mariateresa Fulciniti, Nikhil Munshi
{"title":"Midnolin Downregulation Promotes Myelomagenesis via Impacting Ubiquitination Independent Pathway of Protein Degradation","authors":"Anna Besschetnova, Francesco Ladisa, Anais Schavgoulidze, Shuhui Deng, Jessica Fong Ng, Eugenio Morelli, Mehmet Samur, Christopher Nardone, Xin Gu, Mariateresa Fulciniti, Nikhil Munshi","doi":"10.1016/S2152-2650(25)03432-9","DOIUrl":"10.1016/S2152-2650(25)03432-9","url":null,"abstract":"","PeriodicalId":10348,"journal":{"name":"Clinical Lymphoma, Myeloma & Leukemia","volume":"25 ","pages":"Pages S19-S20"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145098326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prospective Evaluation of Response Assessment in Newly-Diagnosed Multiple Myeloma with Combined use of 18F-FDG-PET/CT, Whole-Body Diffusion-Weighted MRI and MRD by Next-Generation Sequencing 新一代测序联合应用18F-FDG-PET/CT、全身弥散加权MRI和MRD对新诊断多发性骨髓瘤疗效评估的前瞻性评价
IF 2.7 4区 医学
Clinical Lymphoma, Myeloma & Leukemia Pub Date : 2025-09-01 DOI: 10.1016/S2152-2650(25)03423-8
Marco Talarico, Arrigo Cattabriga, Martina Di Franco, Vincenza Solli, Stefano Ghibellini, Ilaria Sacchetti, Enrica Manzato, Simone Masci, Roberta Restuccia, Michele Puppi, Miriam Iezza, Ilaria Rizzello, Katia Mancuso, Lucia Pantani, Paola Tacchetti, Simona Barbato, Carolina Terragna, Stefano Brocchi, Cristina Mosconi, Cristina Nanni, Elena Zamagni
{"title":"Prospective Evaluation of Response Assessment in Newly-Diagnosed Multiple Myeloma with Combined use of 18F-FDG-PET/CT, Whole-Body Diffusion-Weighted MRI and MRD by Next-Generation Sequencing","authors":"Marco Talarico, Arrigo Cattabriga, Martina Di Franco, Vincenza Solli, Stefano Ghibellini, Ilaria Sacchetti, Enrica Manzato, Simone Masci, Roberta Restuccia, Michele Puppi, Miriam Iezza, Ilaria Rizzello, Katia Mancuso, Lucia Pantani, Paola Tacchetti, Simona Barbato, Carolina Terragna, Stefano Brocchi, Cristina Mosconi, Cristina Nanni, Elena Zamagni","doi":"10.1016/S2152-2650(25)03423-8","DOIUrl":"10.1016/S2152-2650(25)03423-8","url":null,"abstract":"","PeriodicalId":10348,"journal":{"name":"Clinical Lymphoma, Myeloma & Leukemia","volume":"25 ","pages":"Page S13"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145098395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monitoring and Management of CMV and other Viral Reactivations with Bispecific Antibodies (BsAbs) for Patients with Relapsed and Refractory Multiple Myeloma (RRMM) 双特异性抗体（BsAbs）对复发难治性多发性骨髓瘤（RRMM）患者CMV和其他病毒再激活的监测和管理
IF 2.7 4区 医学
Clinical Lymphoma, Myeloma & Leukemia Pub Date : 2025-09-01 DOI: 10.1016/S2152-2650(25)03492-5
Alice Feast, Michael Nathan, Victoria Peacock, Dunsi Bolarinwa, James Adams, Emilie Sanchez, Lydia Lee, Eileen Boyle, Annabel McMillan, Kwee Yong, Neil Rabin, Jonathan Sive, Xenofon Papanikolaou, Ke Xu, Charalampia Kyriakou, Sriram Ravichandran, Ashutosh Wechalekar, Jaimal Kothari, William Wilson, Selina Chavda, Rakesh Popat
{"title":"Monitoring and Management of CMV and other Viral Reactivations with Bispecific Antibodies (BsAbs) for Patients with Relapsed and Refractory Multiple Myeloma (RRMM)","authors":"Alice Feast, Michael Nathan, Victoria Peacock, Dunsi Bolarinwa, James Adams, Emilie Sanchez, Lydia Lee, Eileen Boyle, Annabel McMillan, Kwee Yong, Neil Rabin, Jonathan Sive, Xenofon Papanikolaou, Ke Xu, Charalampia Kyriakou, Sriram Ravichandran, Ashutosh Wechalekar, Jaimal Kothari, William Wilson, Selina Chavda, Rakesh Popat","doi":"10.1016/S2152-2650(25)03492-5","DOIUrl":"10.1016/S2152-2650(25)03492-5","url":null,"abstract":"","PeriodicalId":10348,"journal":{"name":"Clinical Lymphoma, Myeloma & Leukemia","volume":"25 ","pages":"Pages S58-S59"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145098399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes of Teclistamab (Tec) Step-Up Dosing in Outpatient/Hybrid Settings Among a Large Sample of Relapsed Refractory Multiple Myeloma (RRMM) Patients Treated with Tec 在接受Tec治疗的复发难治性多发性骨髓瘤（RRMM）患者中，Teclistamab （Tec）在门诊/混合环境中增加剂量的结果
IF 2.7 4区 医学
Clinical Lymphoma, Myeloma & Leukemia Pub Date : 2025-09-01 DOI: 10.1016/S2152-2650(25)03490-1
Binod Dhakal, Gilbert Ko, Jinghua He, Wenze Tang, Sarah Lucht, Camryn Craig, Bruce Feinberg, Tonya Le Blanc, Niodita Gupta-Werner, Shuchita Kaila, Peter Voorhees
{"title":"Outcomes of Teclistamab (Tec) Step-Up Dosing in Outpatient/Hybrid Settings Among a Large Sample of Relapsed Refractory Multiple Myeloma (RRMM) Patients Treated with Tec","authors":"Binod Dhakal, Gilbert Ko, Jinghua He, Wenze Tang, Sarah Lucht, Camryn Craig, Bruce Feinberg, Tonya Le Blanc, Niodita Gupta-Werner, Shuchita Kaila, Peter Voorhees","doi":"10.1016/S2152-2650(25)03490-1","DOIUrl":"10.1016/S2152-2650(25)03490-1","url":null,"abstract":"","PeriodicalId":10348,"journal":{"name":"Clinical Lymphoma, Myeloma & Leukemia","volume":"25 ","pages":"Pages S57-S58"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145099105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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