Circulation: Cardiovascular Interventions最新文献

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Seeing More With Less: AI to Reduce Radiation Exposure in the Cath Lab. 用更少的资源获得更多:人工智能减少导管室的辐射暴露。
IF 7.2 1区 医学
Circulation: Cardiovascular Interventions Pub Date : 2026-07-01 Epub Date: 2026-06-11 DOI: 10.1161/CIRCINTERVENTIONS.126.016980
Thomas Meredith, Celina M Yong, William F Fearon
{"title":"Seeing More With Less: AI to Reduce Radiation Exposure in the Cath Lab.","authors":"Thomas Meredith, Celina M Yong, William F Fearon","doi":"10.1161/CIRCINTERVENTIONS.126.016980","DOIUrl":"10.1161/CIRCINTERVENTIONS.126.016980","url":null,"abstract":"","PeriodicalId":10330,"journal":{"name":"Circulation: Cardiovascular Interventions","volume":" ","pages":"e016980"},"PeriodicalIF":7.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148216699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Timing of Complete Revascularization in Patients With STEMI and Multivessel Disease: An Updated Meta-Analysis of Randomized Clinical Trials. STEMI和多血管疾病患者完全血运重建的时机:随机临床试验的最新荟萃分析
IF 7.2 1区 医学
Circulation: Cardiovascular Interventions Pub Date : 2026-07-01 Epub Date: 2026-04-30 DOI: 10.1161/CIRCINTERVENTIONS.126.016601
Mohammed A Elbahloul, Shrouk Ramadan, Eman E Labeeb, Shahed Aldalahmeh, Ahella Ismail A Mousa, Ahmed Elazab, Ahmed N Mohamed, Ahmad Elashery, Mehiar O El-Hamdani, Carl J Lavie, Gregg W Stone
{"title":"Timing of Complete Revascularization in Patients With STEMI and Multivessel Disease: An Updated Meta-Analysis of Randomized Clinical Trials.","authors":"Mohammed A Elbahloul, Shrouk Ramadan, Eman E Labeeb, Shahed Aldalahmeh, Ahella Ismail A Mousa, Ahmed Elazab, Ahmed N Mohamed, Ahmad Elashery, Mehiar O El-Hamdani, Carl J Lavie, Gregg W Stone","doi":"10.1161/CIRCINTERVENTIONS.126.016601","DOIUrl":"10.1161/CIRCINTERVENTIONS.126.016601","url":null,"abstract":"<p><strong>Background: </strong>The ideal timing for complete revascularization (CR) in patients with ST-segment-elevation myocardial infarction and multivessel disease is uncertain. This meta-analysis examined outcomes of immediate CR (ICR) versus staged CR (SCR).</p><p><strong>Methods: </strong>Four databases were searched for randomized controlled trials that compared ICR and SCR in ST-segment-elevation myocardial infarction and multivessel disease. The primary end points of interest were short-term and long-term all-cause mortality. Outcomes are presented as risk ratios for short-term outcomes and incidence rate ratios for long-term outcomes with 95% CIs.</p><p><strong>Results: </strong>The analysis included 9 randomized controlled trials in which 4213 patients were enrolled. Short-term all-cause mortality occurred in 2.0% of patients after ICR compared with 1.2% of patients after SCR (risk ratio, 1.66 [95% CI, 0.99-2.78], <i>P</i>=0.053; <i>I</i><sup>2</sup>=0%). Short-term cardiac death was increased after ICR (risk ratio, 2.19 [95% CI, 1.08-4.44], <i>P</i>=0.03; <i>I</i><sup>2</sup>=0%). At a median 1-year follow-up, all-cause mortality occurred in 4.7% of patients after ICR compared with 3.5% of patients after SCR (incidence rate ratio, 1.40 [95% CI, 0.97-2.03], <i>P</i>=0.07; <i>I</i><sup>2</sup>=0%). No significant differences were identified between the ICR and SCR strategies at either short-term or long-term follow-up for other outcomes, including myocardial infarction, repeat revascularization, stent thrombosis, stroke, major bleeding, and the composite of major adverse cardiac or cerebrovascular events.</p><p><strong>Conclusions: </strong>In hemodynamically stable patients with ST-segment-elevation myocardial infarction and multivessel disease, an ICR strategy may increase short-term cardiac death compared with SCR, and the possibility of increased early and late all-cause mortality cannot be excluded. Despite some uncertainty, these results currently favor a staged CR strategy for most patients with ST-segment-elevation myocardial infarction and multivessel disease.</p><p><strong>Registration: </strong>URL: https://www.crd.york.ac.uk/PROSPERO/; Unique identifier: CRD420251163719.</p>","PeriodicalId":10330,"journal":{"name":"Circulation: Cardiovascular Interventions","volume":" ","pages":"e016601"},"PeriodicalIF":7.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147764385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Durability of Bioprosthetic and Mechanical Valves Implanted for Aortic Valve Replacement in Pediatric Patients. 儿童主动脉瓣置换术中植入生物假体和机械瓣膜的耐久性。
IF 7.2 1区 医学
Circulation: Cardiovascular Interventions Pub Date : 2026-07-01 Epub Date: 2026-04-23 DOI: 10.1161/CIRCINTERVENTIONS.125.015931
Rumi Yokota, Yulin Zhang, Ayush Jaggi, Tristan Perry, Elisabeth Martin, Michael Ma, Rajesh Punn, Frank L Hanley, Doff B McElhinney
{"title":"Durability of Bioprosthetic and Mechanical Valves Implanted for Aortic Valve Replacement in Pediatric Patients.","authors":"Rumi Yokota, Yulin Zhang, Ayush Jaggi, Tristan Perry, Elisabeth Martin, Michael Ma, Rajesh Punn, Frank L Hanley, Doff B McElhinney","doi":"10.1161/CIRCINTERVENTIONS.125.015931","DOIUrl":"10.1161/CIRCINTERVENTIONS.125.015931","url":null,"abstract":"<p><strong>Background: </strong>There is limited published information on bioprosthetic aortic valve durability. The purpose of this study was to assess the durability of bioprosthetic valves used for aortic valve replacement (AVR) in pediatric patients.</p><p><strong>Methods: </strong>We reviewed all surgical AVR procedures performed from May 2002 to July 2024 in patients ≤21 years of age using a mechanical valve or bioprosthesis. Long-term valve-related outcomes were assessed with propensity-score-adjusted analysis.</p><p><strong>Results: </strong>During the study period, 180 AVR procedures were performed in pediatric patients (median age, 14.3 years) using a bioprosthetic valve (n=79) or mechanical prosthesis (n=101). Freedom from reintervention was significantly shorter in patients with a bioprosthetic valve (77% at 5 years, 29% at 10 years) than those with a mechanical valve (88% at 5 years, 82% at 10 years; <i>P</i><0.001). By propensity score-adjusted multivariable Cox regression, a bioprosthetic valve (hazard ratio, 4.66 [95% CI, 2.26-9.62]; <i>P</i><0.001) and age <12 years at AVR (3.26 [1.81-5.87]; <i>P</i><0.001) were associated with shorter freedom from reintervention. Endocarditis was diagnosed in 16 patients, and thromboembolic or bleeding complications were reported in 8.</p><p><strong>Conclusions: </strong>In pediatric patients undergoing AVR, bioprosthetic valves have significantly worse durability than mechanical prostheses, with the disparity most pronounced in younger patients. Valve-related mortality and complications were relatively common. These findings should focus attention on the need for better replacement valves or therapeutic options in young patients with aortic valve disease.</p>","PeriodicalId":10330,"journal":{"name":"Circulation: Cardiovascular Interventions","volume":" ","pages":"e015931"},"PeriodicalIF":7.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147764365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic Impact of Renal Function on Outcomes After Physiology-Guided Coronary Revascularization: Insights From the J-PRIDE Registry. 生理引导冠状动脉血运重建术后肾功能对预后的影响:来自J-PRIDE登记的见解。
IF 7.2 1区 医学
Circulation: Cardiovascular Interventions Pub Date : 2026-07-01 Epub Date: 2026-04-27 DOI: 10.1161/CIRCINTERVENTIONS.125.016454
Hirofumi Ohashi, Shoichi Kuramitsu, Hirohiko Ando, Tomohiro Shinozaki, Yoshiaki Kawase, Takenori Domei, Futoshi Yamanaka, Umihiko Kaneko, Tsunekazu Kakuta, Kazunori Horie, Hidenobu Terai, Yasutsugu Shiono, Toru Tagashira, Kazutaka Nogi, Takashi Kubo, Taku Asano, Jun Shiraishi, Hiromasa Otake, Akinori Sugano, Hiroki Okabe, Atsushi Iwai, Yuetsu Kikuta, Hidetaka Nishina, Masashi Iwabuchi, Hiroyoshi Yokoi, Takashi Akasaka, Hitoshi Matsuo, Nobuhiro Tanaka, Tetsuya Amano
{"title":"Prognostic Impact of Renal Function on Outcomes After Physiology-Guided Coronary Revascularization: Insights From the J-PRIDE Registry.","authors":"Hirofumi Ohashi, Shoichi Kuramitsu, Hirohiko Ando, Tomohiro Shinozaki, Yoshiaki Kawase, Takenori Domei, Futoshi Yamanaka, Umihiko Kaneko, Tsunekazu Kakuta, Kazunori Horie, Hidenobu Terai, Yasutsugu Shiono, Toru Tagashira, Kazutaka Nogi, Takashi Kubo, Taku Asano, Jun Shiraishi, Hiromasa Otake, Akinori Sugano, Hiroki Okabe, Atsushi Iwai, Yuetsu Kikuta, Hidetaka Nishina, Masashi Iwabuchi, Hiroyoshi Yokoi, Takashi Akasaka, Hitoshi Matsuo, Nobuhiro Tanaka, Tetsuya Amano","doi":"10.1161/CIRCINTERVENTIONS.125.016454","DOIUrl":"10.1161/CIRCINTERVENTIONS.125.016454","url":null,"abstract":"<p><strong>Background: </strong>The clinical utility of physiology-guided revascularization for decision-making in patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD) remains uncertain. The aim of this study is to evaluate the diagnostic performance and prognostic significance of fractional flow reserve (FFR) and nonhyperemic pressure ratios (NHPRs) according to the severity of CKD.</p><p><strong>Methods: </strong>This subanalysis of the J-PRIDE registry, a prospective multicenter study conducted at 20 Japanese centers between September 2019 and February 2021, included 4296 lesions from 3194 patients who underwent both FFR and NHPR assessment. Patients were categorized by estimated glomerular filtration rate into non-CKD (≥60 mL/min per 1.73 m<sup>2</sup>; n=1639), CKD (15-59; n=1321), and ESRD (<15 or on dialysis; n=234). The primary end point was 1-year target vessel failure, defined as a composite of cardiac death, target vessel myocardial infarction, and clinically driven target vessel revascularization.</p><p><strong>Results: </strong>The 1-year incidence of target vessel failure was significantly higher in the ESRD group than in CKD and non-CKD groups (8.4% versus 2.4% and 2.6%; for CKD, adjusted hazard ratio, 3.09 [95% CI, 1.60-5.96]; <i>P</i><0.001; for non-CKD, adjusted hazard ratio, 2.88 [95% CI, 1.98-5.47]; <i>P</i>=0.001). The NHPR cutoff predicting FFR ≤0.80 was lower in ESRD compared with CKD and non-CKD (0.85 versus 0.89 versus 0.89). Although the overall prevalence of FFR/NHPR discordance was comparable (23.6%, 19.7%, and 19.7%; <i>P</i>=0.24), FFR-/NHPR+ discordance predominated in ESRD (18.6% versus 9.3% versus 7.0%; <i>P</i><0.001). FFR-/NHPR+ lesions in the ESRD group exhibited an excess risk compared with other lesions. Revascularization was beneficial in non-CKD patients with FFR+/NHPR- lesions, whereas no clear benefit was observed in patients with CKD and ESRD.</p><p><strong>Conclusions: </strong>Patients with ESRD exhibited distinct physiological characteristics and substantially worse outcomes, highlighting the need for tailored coronary revascularization strategies in this population.</p><p><strong>Registration: </strong>URL: https://www.umin.ac.jp/ctr; Unique identifier: UMIN000038403.</p>","PeriodicalId":10330,"journal":{"name":"Circulation: Cardiovascular Interventions","volume":" ","pages":"e016454"},"PeriodicalIF":7.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147764363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Outcomes of Bail-Out Stenting After Drug-Coated Balloon Angioplasty: The International Multicenter BAILOUT Registry. 药物包被球囊血管成形术后置入术的临床结果:国际多中心救助登记。
IF 7.2 1区 医学
Circulation: Cardiovascular Interventions Pub Date : 2026-07-01 Epub Date: 2026-04-30 DOI: 10.1161/CIRCINTERVENTIONS.125.016461
Mauro Gitto, Pier Pasquale Leone, Tuomas T Rissanen, Natasha Corballis, Gianmaria Calamita, Francesco Tartaglia, Andrea Buono, Marco Ferrone, Alfonso Ielasi, Siamion Pismiankou, Marco Luciano Rossi, Ioannis Merinopoulos, Vassilios S Vassiliou, Luigi Salemme, Mauro Chiarito, Michele Galasso, Michele Morosato, Kasper Kyhl, Giovanni Occhipinti, Jonathan Hinton, Elodi Bacci, Guido Vellucci, Marcello Marchetta, Francesca De Micco, Damiano Regazzoli, Antonio Mangieri, Thomas Johnson, Fabrizio Ugo, Gabriele Gasparini, Bernhard Reimers, Peter O' Kane, Giuseppe Massimo Sangiorgi, Giulio G Stefanini, Stefano Galli, Fernando Alfonso, Diego Arroyo, Manel Sabaté, Carlo Briguori, Tullio Tesorio, Kambis Mashayekhi, Diego Maffeo, Azeem Latib, Simon Eccleshall, Antonio Colombo
{"title":"Clinical Outcomes of Bail-Out Stenting After Drug-Coated Balloon Angioplasty: The International Multicenter BAILOUT Registry.","authors":"Mauro Gitto, Pier Pasquale Leone, Tuomas T Rissanen, Natasha Corballis, Gianmaria Calamita, Francesco Tartaglia, Andrea Buono, Marco Ferrone, Alfonso Ielasi, Siamion Pismiankou, Marco Luciano Rossi, Ioannis Merinopoulos, Vassilios S Vassiliou, Luigi Salemme, Mauro Chiarito, Michele Galasso, Michele Morosato, Kasper Kyhl, Giovanni Occhipinti, Jonathan Hinton, Elodi Bacci, Guido Vellucci, Marcello Marchetta, Francesca De Micco, Damiano Regazzoli, Antonio Mangieri, Thomas Johnson, Fabrizio Ugo, Gabriele Gasparini, Bernhard Reimers, Peter O' Kane, Giuseppe Massimo Sangiorgi, Giulio G Stefanini, Stefano Galli, Fernando Alfonso, Diego Arroyo, Manel Sabaté, Carlo Briguori, Tullio Tesorio, Kambis Mashayekhi, Diego Maffeo, Azeem Latib, Simon Eccleshall, Antonio Colombo","doi":"10.1161/CIRCINTERVENTIONS.125.016461","DOIUrl":"10.1161/CIRCINTERVENTIONS.125.016461","url":null,"abstract":"<p><strong>Background: </strong>Drug-coated balloons (DCBs) are increasingly adopted in percutaneous coronary intervention. Bail-out drug-eluting stent (DES) implantation due to suboptimal immediate results after DCB angioplasty is not infrequent, and the clinical outcomes of percutaneous coronary intervention with DCB angioplasty followed by bail-out DES implantation remain unexplored. The aim of this study was to evaluate the safety of bail-out DES implantation following DCB angioplasty in percutaneous coronary intervention.</p><p><strong>Methods: </strong>The BAILOUT registry included consecutive patients undergoing bail-out DES implantation after DCB angioplasty at 17 European centers between 2011 and 2024. The primary end point was target lesion failure (TLF) at 1 year, defined as the composite of target lesion revascularization, target vessel myocardial infarction, and cardiac death. The TLF rate was compared with a performance goal of 7.0% for an upfront DES-only strategy, derived from a meta-analysis of contemporary randomized controlled trials.</p><p><strong>Results: </strong>A total of 733 patients were included, accounting for 5.5% of all DCB-based percutaneous coronary interventions. At 1 year, the cumulative TLF incidence in the overall population was 7.0% (95% CI, 5.2%-9.3%), which was comparable to the performance goal (<i>P</i>=0.916). This was mainly driven by target lesion revascularization (4.1%), while cardiac death and target vessel myocardial infarction occurred both in 1.9% of patients. The incidence of stent thrombosis was 0.6%. Independent predictors of 1-year TLF included lesion length (hazard ratio, 1.02 per mm increase [95% CI, 1.01-1.03]; <i>P</i><0.001), moderate-to-severe calcification (hazard ratio, 2.82 [95% CI, 1.48-5.40]; <i>P</i>=0.002), and the use of paclitaxel- versus sirolimus-coated balloons (hazard ratio, 1.99 [95% CI, 1.01-4.05]; <i>P</i>=0.048).</p><p><strong>Conclusions: </strong>In cases of suboptimal angiographic results after DCB angioplasty, bail-out DES implantation is safe, with no increased risk of TLF at 1 year compared with the expected performance goal for an upfront DES-only strategy.</p>","PeriodicalId":10330,"journal":{"name":"Circulation: Cardiovascular Interventions","volume":" ","pages":"e016461"},"PeriodicalIF":7.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147764404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Measured Versus Predicted Prosthesis-Patient Mismatch after TAVR in Sievers Type 1 BAV: Incidence, Determinants, and Outcomes From the AD-HOC Registry. Sievers 1型BAV TAVR后测量的与预测的假体-患者不匹配:AD-HOC注册的发生率、决定因素和结果
IF 7.2 1区 医学
Circulation: Cardiovascular Interventions Pub Date : 2026-07-01 Epub Date: 2026-05-12 DOI: 10.1161/CIRCINTERVENTIONS.125.015994
Tommaso Fabris, Federico Arturi, Andrea Buono, Chiara de Biase, Michele Bellamoli, Andrea Zito, Antonio Mangieri, Nicholas Montarello, Giuliano Costa, Mesfer Alfadhel, Ofi Koren, Simone Fezzi, Barbara Bellini, Mauro Massussi, Andrea Scotti, Lin Bai, Giulia Costa, Alessandro Mazzapicchi, Enrico Giacomin, Riccardo Gorla, Karsten Hug, Carlo Briguori, Luca Bettari, Antonio Messina, Mauro Boiago, Matthias Renker, Mario Garcia Gomez, Massimo Napodano, Chiara Fraccaro, Luca Nai Fovino, Giulia Masiero, Francesco Cardaioli, Francesco Putortì, Andrea Panza, Maria Luisa De Rosa, Carlo Trani, Giulia Laterra, Alessia Latini, Dario Pellegrini, Alfonso Ielasi, Ady Orbach, Uri Landes, Tobias Rheude, Luca Testa, Ignacio Amat Santos, Francesco Saia, Luca Favero, Carlo Cernetti, Mao Chen, Marianna Adamo, Azeem Latib, Anna Sonia Petronio, Matteo Montorfano, Raj R Makkar, Francesco Burzotta, Marco Barbanti, Daniel J Blackman, Darren Mylotte, Ole De Backer, Didier Tchètchè, Diego Maffeo, Won-Keun Kim, Giuseppe Tarantini
{"title":"Measured Versus Predicted Prosthesis-Patient Mismatch after TAVR in Sievers Type 1 BAV: Incidence, Determinants, and Outcomes From the AD-HOC Registry.","authors":"Tommaso Fabris, Federico Arturi, Andrea Buono, Chiara de Biase, Michele Bellamoli, Andrea Zito, Antonio Mangieri, Nicholas Montarello, Giuliano Costa, Mesfer Alfadhel, Ofi Koren, Simone Fezzi, Barbara Bellini, Mauro Massussi, Andrea Scotti, Lin Bai, Giulia Costa, Alessandro Mazzapicchi, Enrico Giacomin, Riccardo Gorla, Karsten Hug, Carlo Briguori, Luca Bettari, Antonio Messina, Mauro Boiago, Matthias Renker, Mario Garcia Gomez, Massimo Napodano, Chiara Fraccaro, Luca Nai Fovino, Giulia Masiero, Francesco Cardaioli, Francesco Putortì, Andrea Panza, Maria Luisa De Rosa, Carlo Trani, Giulia Laterra, Alessia Latini, Dario Pellegrini, Alfonso Ielasi, Ady Orbach, Uri Landes, Tobias Rheude, Luca Testa, Ignacio Amat Santos, Francesco Saia, Luca Favero, Carlo Cernetti, Mao Chen, Marianna Adamo, Azeem Latib, Anna Sonia Petronio, Matteo Montorfano, Raj R Makkar, Francesco Burzotta, Marco Barbanti, Daniel J Blackman, Darren Mylotte, Ole De Backer, Didier Tchètchè, Diego Maffeo, Won-Keun Kim, Giuseppe Tarantini","doi":"10.1161/CIRCINTERVENTIONS.125.015994","DOIUrl":"10.1161/CIRCINTERVENTIONS.125.015994","url":null,"abstract":"<p><strong>Background: </strong>Evidence regarding prosthesis-patient mismatch (PPM), measured (mPPM), and predicted (pPPM), after transcatheter aortic valve replacement in bicuspid aortic valve stenosis remains limited. This study sought to evaluate the incidence, predictors, and prognostic implications of mPPM and pPPM in patients with Sievers type 1 bicuspid aortic valve undergoing transcatheter aortic valve replacement.</p><p><strong>Methods: </strong>The AD-HOC registry is a retrospective, multicenter study including 781 patients with severe aortic stenosis and bicuspid aortic valve treated with transcatheter aortic valve replacement between 2016 and 2023 across 24 centers. PPM was defined according to Valve Academic Research Consortium-3 criteria. The primary outcome was all-cause mortality.</p><p><strong>Results: </strong>Moderate-to-severe mPPM was more frequent than pPPM (22% versus 8%; <i>P</i><0.001). Balloon-expandable valves were independently associated with both mPPM and pPPM, while smaller valve size and supra-annular sizing predicted only pPPM. During a mean follow-up of 621±470 days, neither mPPM nor pPPM was associated with mortality in the overall cohort. Among patients with a small annulus (≤430 mm<sup>2</sup>; n=145), pPPM occurrence was significantly higher (19% versus 5.5%; <i>P</i><0.001) and was associated with increased all-cause mortality, but not with cardiovascular mortality.</p><p><strong>Conclusions: </strong>In patients with Sievers type 1 bicuspid aortic valve undergoing transcatheter aortic valve replacement, pPPM occurred less frequently than mPPM and was predominantly driven by anatomic characteristics and sizing strategies. Although pPPM was associated with increased all-cause mortality among patients with small annuli, this association did not extend to cardiovascular mortality and should be considered hypothesis-generating. Further prospective investigations are warranted to better delineate the impact of anatomic constraints on clinical outcomes in this anatomically challenging subset.</p>","PeriodicalId":10330,"journal":{"name":"Circulation: Cardiovascular Interventions","volume":" ","pages":"e015994"},"PeriodicalIF":7.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13384377/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147873727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contrast-Derived Index of Microcirculatory Resistance: A Novel Index for Measuring Coronary Microvascular Resistance. 对比衍生的微循环阻力指数(cIMR):一种测量冠状动脉微血管阻力的新指标。
IF 7.2 1区 医学
Circulation: Cardiovascular Interventions Pub Date : 2026-07-01 Epub Date: 2026-05-07 DOI: 10.1161/CIRCINTERVENTIONS.126.016489
Domenico Galante, Ciro Pollio Benvenuto, Andrea Viceré, Simona Todisco, Chiara Giuliana, Vincenzo Viccaro, Pierpaolo Tarzia, Lazzaro Paraggio, Mattia Lunardi, Cristina Aurigemma, Enrico Romagnoli, Rocco A Montone, Gennaro Capalbo, Carlo Trani, Filippo Crea, Francesco Burzotta, Antonio Maria Leone
{"title":"Contrast-Derived Index of Microcirculatory Resistance: A Novel Index for Measuring Coronary Microvascular Resistance.","authors":"Domenico Galante, Ciro Pollio Benvenuto, Andrea Viceré, Simona Todisco, Chiara Giuliana, Vincenzo Viccaro, Pierpaolo Tarzia, Lazzaro Paraggio, Mattia Lunardi, Cristina Aurigemma, Enrico Romagnoli, Rocco A Montone, Gennaro Capalbo, Carlo Trani, Filippo Crea, Francesco Burzotta, Antonio Maria Leone","doi":"10.1161/CIRCINTERVENTIONS.126.016489","DOIUrl":"10.1161/CIRCINTERVENTIONS.126.016489","url":null,"abstract":"","PeriodicalId":10330,"journal":{"name":"Circulation: Cardiovascular Interventions","volume":" ","pages":"e016489"},"PeriodicalIF":7.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultra-Low-Dose Noise-Free Technology to Reduce Radiation Exposure During Coronary Angiography. 超低剂量无噪声技术减少冠状动脉造影期间的辐射暴露。
IF 7.2 1区 医学
Circulation: Cardiovascular Interventions Pub Date : 2026-07-01 Epub Date: 2026-04-21 DOI: 10.1161/CIRCINTERVENTIONS.126.016542
Jinying Zhou, Qiyu Zhang, Hao Lu, Yizhe Wu, Li Shen, Jianying Ma, Rende Xu, Feng Zhang, Zhangwei Chen, Juying Qian, Chenguang Li, Junbo Ge
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引用次数: 0
Transcatheter Mitral Valve-in-Valve: Optimal Sizing and Expansion Matter. 经导管二尖瓣内瓣:最佳尺寸和膨胀问题。
IF 7.2 1区 医学
Circulation: Cardiovascular Interventions Pub Date : 2026-07-01 Epub Date: 2026-06-24 DOI: 10.1161/CIRCINTERVENTIONS.126.016982
Philippe Pibarot
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引用次数: 0
Novel Application of a Familiar Concept: TR Proportionality and T-TEER Outcomes. 一个熟悉概念的新应用:TR比例和T-TEER结果。
IF 7.2 1区 医学
Circulation: Cardiovascular Interventions Pub Date : 2026-06-01 Epub Date: 2026-04-27 DOI: 10.1161/CIRCINTERVENTIONS.126.016819
Jonathan E Labin, Serge Harb, Grant W Reed
{"title":"Novel Application of a Familiar Concept: TR Proportionality and T-TEER Outcomes.","authors":"Jonathan E Labin, Serge Harb, Grant W Reed","doi":"10.1161/CIRCINTERVENTIONS.126.016819","DOIUrl":"10.1161/CIRCINTERVENTIONS.126.016819","url":null,"abstract":"","PeriodicalId":10330,"journal":{"name":"Circulation: Cardiovascular Interventions","volume":" ","pages":"e016819"},"PeriodicalIF":7.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147764440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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