Clinical and Experimental Emergency Medicine最新文献

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Advances in metabolomics in critically ill patients with Sepsis and Septic Shock. 脓毒症和败血症休克重症患者代谢组学研究进展。
IF 1.9
Clinical and Experimental Emergency Medicine Pub Date : 2024-07-19 DOI: 10.15441/ceem.24.211
Swarnima Pandey
{"title":"Advances in metabolomics in critically ill patients with Sepsis and Septic Shock.","authors":"Swarnima Pandey","doi":"10.15441/ceem.24.211","DOIUrl":"https://doi.org/10.15441/ceem.24.211","url":null,"abstract":"<p><p>Sepsis accounts for high cases of morbidity and mortality in hospitalized patients. It has a very complex pathophysiology and swiftly progresses to a severe form of the disease, such as septic shock leading to organ dysfunction, organ failure, and death. Metabolomics has transformed sepsis's clinical and research topography with its application in prognosis, diagnosis, and risk assessment in patients with sepsis and septic shock. Metabolites in blood and urine are detected and analyzed, which helps in understanding the pathogenesis of the disease and aid in better disease management by identifying biomarkers early on. Metabolomics, sepsis and septic shock were the keywords were searched in PubMed and Scopus, from its inception to Dec 2023. This article provides information regarding metabolic profiling performed in sepsis and septic shock We demonstrated that metabolomics will change the world of sepsis by analyzing and detecting the diagnosis, prognosis, mortality, and treatment response biomarkers.</p>","PeriodicalId":10325,"journal":{"name":"Clinical and Experimental Emergency Medicine","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141723139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Point-of-care ultrasound by emergency physicians for direct ureteral stone detection: a case series and review of the literature. 由急诊医生进行护理点超声波输尿管结石检测:病例系列和文献综述。
IF 1.9
Clinical and Experimental Emergency Medicine Pub Date : 2024-06-01 Epub Date: 2024-01-29 DOI: 10.15441/ceem.23.096
Nadav Granat, Evan Avraham Alpert
{"title":"Point-of-care ultrasound by emergency physicians for direct ureteral stone detection: a case series and review of the literature.","authors":"Nadav Granat, Evan Avraham Alpert","doi":"10.15441/ceem.23.096","DOIUrl":"10.15441/ceem.23.096","url":null,"abstract":"<p><p>Symptomatic urolithiasis is a common cause of emergency department visits, with noncontrast computed tomography considered the imaging gold standard. According to the current guidelines, point-of-care ultrasound (POCUS) is limited to evaluating hydronephrosis as a secondary sign of acute ureteral stones. However, the use of POCUS to detect ureteral stones may lead to decreased radiation to the patient and a more rapid diagnosis. This case series describes 10 patients with suspected symptomatic urolithiasis who were diagnosed accurately by emergency physicians using POCUS to detect obstructive ureteral stones. In three of the cases, POCUS significantly changed the patient's management. This article also describes the proper techniques for the emergency physician to learn to master POCUS for ureteral stone detection.</p>","PeriodicalId":10325,"journal":{"name":"Clinical and Experimental Emergency Medicine","volume":" ","pages":"218-223"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11237256/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139575286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic utility of paraspinal muscle index in elderly patients with community-acquired pneumonia. 社区获得性肺炎老年患者脊柱旁肌肉指数的预后效用。
IF 1.9
Clinical and Experimental Emergency Medicine Pub Date : 2024-06-01 Epub Date: 2024-01-29 DOI: 10.15441/ceem.23.142
Ga Ram Lee, Seok Hoon Ko, Hang Sung Choi, Hoon Pyo Hong, Jong Seok Lee, Ki Young Jeong
{"title":"Prognostic utility of paraspinal muscle index in elderly patients with community-acquired pneumonia.","authors":"Ga Ram Lee, Seok Hoon Ko, Hang Sung Choi, Hoon Pyo Hong, Jong Seok Lee, Ki Young Jeong","doi":"10.15441/ceem.23.142","DOIUrl":"10.15441/ceem.23.142","url":null,"abstract":"<p><strong>Objective: </strong>This study investigated the associations between paraspinal muscle measurements on chest computed tomography and clinical outcomes of elderly patients with community-acquired pneumonia (CAP).</p><p><strong>Methods: </strong>This single-center, retrospective, observational study analyzed elderly patients (≥65 years) with CAP hospitalized through an emergency department between March 2020 and December 2022. We collected their baseline characteristics and laboratory data at the time of admission. The paraspinal muscle index and attenuation were calculated at the level of the 12th thoracic vertebra using chest computed tomography taken within 48 hours before or after admission. Univariable and multivariable logistic regression analyses were conducted to evaluate the association between paraspinal muscle measurements and 28-day mortality. Receiver operating characteristic (ROC) curve and area under the curve (AUC) analyses were used to evaluate the prognostic predictive power.</p><p><strong>Results: </strong>Of the 338 enrolled patients, 60 (17.8%) died within 28 days after admission. A high paraspinal muscle index was associated with low 28-day mortality in elderly patients with CAP (adjusted odds ratio, 0.994; 95% confidence interval, 0.992-0.997). The area under the ROC curve for the muscle index was 0.75, which outperformed the pneumonia severity index and the CURB-65 (confusion, urea, respiratory rate, blood pressure, age ≥65 years) metric, both of which showed an AUC of 0.64 in predicting mortality.</p><p><strong>Conclusion: </strong>A high paraspinal muscle index was associated with low 28-day mortality in patients aged 65 years or older with CAP.</p>","PeriodicalId":10325,"journal":{"name":"Clinical and Experimental Emergency Medicine","volume":" ","pages":"171-180"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11237258/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139575292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bezold abscess in a 4-year-old: an exceptionally rare complication of otitis media. 4 岁儿童的贝佐德脓肿:中耳炎的罕见并发症。
IF 1.9
Clinical and Experimental Emergency Medicine Pub Date : 2024-06-01 Epub Date: 2024-02-16 DOI: 10.15441/ceem.23.034
Zachary Tillett, Robert Anderson
{"title":"Bezold abscess in a 4-year-old: an exceptionally rare complication of otitis media.","authors":"Zachary Tillett, Robert Anderson","doi":"10.15441/ceem.23.034","DOIUrl":"10.15441/ceem.23.034","url":null,"abstract":"","PeriodicalId":10325,"journal":{"name":"Clinical and Experimental Emergency Medicine","volume":" ","pages":"229-230"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11237261/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139899496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The predictive value of point-of-care ultrasonography versus magnetic resonance imaging in assessing medial meniscal tears in patients with acute knee injury. 在评估急性膝关节损伤患者内侧半月板撕裂时,护理点超声波与核磁共振成像的预测价值。
IF 1.9
Clinical and Experimental Emergency Medicine Pub Date : 2024-06-01 Epub Date: 2024-01-29 DOI: 10.15441/ceem.23.111
Omid Ahmadi, Mehdi Motififard, Farhad Heydari, Saeed Hatami, Azita Azimi Meibody
{"title":"The predictive value of point-of-care ultrasonography versus magnetic resonance imaging in assessing medial meniscal tears in patients with acute knee injury.","authors":"Omid Ahmadi, Mehdi Motififard, Farhad Heydari, Saeed Hatami, Azita Azimi Meibody","doi":"10.15441/ceem.23.111","DOIUrl":"10.15441/ceem.23.111","url":null,"abstract":"<p><strong>Objective: </strong>Musculoskeletal ultrasound is increasingly used as the modality of choice in diagnosing many medical situations. The present study aimed to compare the accuracy of point-of-care ultrasonography (POCUS) and magnetic resonance imaging (MRI) to detect acute medial meniscus tears in knee.</p><p><strong>Methods: </strong>The prospective study was conducted on patients with suspected medial meniscus tears in knee. in the emergency department. In the absence of a knee fracture on x-ray, POCUS on the knee was performed. All patients underwent POCUS and MRI of the knee followed by arthroscopy. POCUS findings were then compared to MRI findings to diagnose medial meniscus tears.</p><p><strong>Results: </strong>A final total of 157 patients with a mean age of 25.04±7.41 years was included. Out of 157 patients, 94 (59.9%) were male. Medial meniscus tears were detected in 89 patients (56.7%) using arthroscopy as the gold standard. The sensitivity, specificity, positive and negative predictive values, and accuracy of POCUS to detect medial meniscus tears were 88.8% (95% confidence interval [CI], 80.3%-94.5%), 89.7% (95% CI, 79.9%-95.8%), 91.9% (95% CI, 84.8%-95.8%), 85.9% (95% CI, 77.2%-91.7%), and 89.2% (95% CI, 83.3%-93.6%), respectively. The diagnostic accuracy of MRI to detect medial meniscus injury was 93.0% (95% CI, 87.8%- 96.4%).</p><p><strong>Conclusion: </strong>The present study demonstrated that POCUS is an accurate and reliable diagnostic tool alternative to MRI in detecting medial meniscal tears. POCUS had acceptable sensitivity, specificity, and accuracy in detecting meniscal injuries and could be performed as an effective immediate investigation to guide further modalities in patients with acute knee trauma.</p>","PeriodicalId":10325,"journal":{"name":"Clinical and Experimental Emergency Medicine","volume":" ","pages":"188-194"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11237262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139575278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modern management of acute atrial fibrillation and atrial flutter. 急性心房颤动和心房扑动的现代管理。
IF 1.9
Clinical and Experimental Emergency Medicine Pub Date : 2024-06-01 Epub Date: 2024-01-29 DOI: 10.15441/ceem.23.152
Ian G Stiell, Debra Eagles
{"title":"Modern management of acute atrial fibrillation and atrial flutter.","authors":"Ian G Stiell, Debra Eagles","doi":"10.15441/ceem.23.152","DOIUrl":"10.15441/ceem.23.152","url":null,"abstract":"","PeriodicalId":10325,"journal":{"name":"Clinical and Experimental Emergency Medicine","volume":" ","pages":"213-217"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11237266/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139575283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Local anesthetic systemic toxicity: awareness, recognition, and risk mitigation in the emergency department. 局麻药全身毒性:急诊科的认识、识别和风险缓解。
IF 1.9
Clinical and Experimental Emergency Medicine Pub Date : 2024-06-01 Epub Date: 2024-05-23 DOI: 10.15441/ceem.24.231
Michael Shalaby, Raghav Sahni, Richard Hamilton
{"title":"Local anesthetic systemic toxicity: awareness, recognition, and risk mitigation in the emergency department.","authors":"Michael Shalaby, Raghav Sahni, Richard Hamilton","doi":"10.15441/ceem.24.231","DOIUrl":"10.15441/ceem.24.231","url":null,"abstract":"","PeriodicalId":10325,"journal":{"name":"Clinical and Experimental Emergency Medicine","volume":" ","pages":"121-126"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11237253/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141080703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The mortality of patients with sepsis increases in the first month of a new academic year. 败血症患者的死亡率在新学年的第一个月有所上升。
IF 1.9
Clinical and Experimental Emergency Medicine Pub Date : 2024-06-01 Epub Date: 2024-01-29 DOI: 10.15441/ceem.23.117
Sukyo Lee, Sungjin Kim, Sejoong Ahn, Hanjin Cho, Sungwoo Moon, Young Duck Cho, Jong-Hak Park
{"title":"The mortality of patients with sepsis increases in the first month of a new academic year.","authors":"Sukyo Lee, Sungjin Kim, Sejoong Ahn, Hanjin Cho, Sungwoo Moon, Young Duck Cho, Jong-Hak Park","doi":"10.15441/ceem.23.117","DOIUrl":"10.15441/ceem.23.117","url":null,"abstract":"<p><strong>Objective: </strong>Many studies have examined the July effect. However, little is known about the July effect in sepsis. We hypothesized that the July effect would result in worse outcomes for patients with sepsis.</p><p><strong>Methods: </strong>Data from patients with sepsis, collected prospectively between January 2018 and December 2021, were analyzed. In Korea, the new academic year starts on March 1, so the \"July effect\" appears in March. The primary outcome was 30-day mortality. Secondary outcomes included adherence to the Surviving Sepsis Campaign bundle. Outcomes in March were compared to other months. A multivariate Cox proportional hazard regression was performed to adjust for confounders.</p><p><strong>Results: </strong>We included 843 patients. There were no significant differences in sepsis severity. The 30-day mortality in March was higher (49.0% vs. 28.5%, P<0.001). However, there was no difference in bundle adherence in March (42.2% vs. 48.0%, P=0.264). The multivariate Cox proportional hazard regression showed that the July effect was associated with 30-day mortality in patients with sepsis (adjusted hazard ratio, 1.925; 95% confidence interval, 1.405-2.638; P<0.001).</p><p><strong>Conclusion: </strong>The July effect was associated with 30-day mortality in patients with sepsis. However, bundle adherence did not differ. These.</p><p><strong>Results: </strong>suggest that the increase in mortality during the turnover period might be related to unmeasured in-hospital management. Intensive supervision and education of residents caring for patients with sepsis is needed in the beginning of training.</p>","PeriodicalId":10325,"journal":{"name":"Clinical and Experimental Emergency Medicine","volume":" ","pages":"161-170"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11237255/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139575270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preoxygenation and apneic oxygenation in emergency airway management. 紧急气道管理中的预吸氧和窒息吸氧。
IF 1.9
Clinical and Experimental Emergency Medicine Pub Date : 2024-06-01 Epub Date: 2024-01-29 DOI: 10.15441/ceem.23.089
Alexandra Barbosa, Jarrod M Mosier
{"title":"Preoxygenation and apneic oxygenation in emergency airway management.","authors":"Alexandra Barbosa, Jarrod M Mosier","doi":"10.15441/ceem.23.089","DOIUrl":"10.15441/ceem.23.089","url":null,"abstract":"<p><p>Preoxygenation during the peri-intubation period is now considered a critical aspect of rapid sequence intubation and an important skill for emergency medicine and critical care providers. Peri-intubation hypoxemia carries significant risk, including cardiac arrest, and care must be taken for appropriate management including through apnea and initiation of laryngoscopy. Appropriate selection of preoxygenation devices should depend on underlying physiology to optimize oxygenation prior to intubation attempts. A PubMed MEDLINE search was completed with selection of articles from March 2008 to March 2023 describing various techniques for preoxygenation for intubation in the critical care and operating room setting with pregnant and obese patient populations included. Prehospital and pediatric populations were excluded in this review. This review provides an overview of methods of preoxygenation with their clinical indications as well as methods for determining end points to preoxygenation and apneic oxygenation. An overview of approaches to preoxygenation was included for patients considered to have a physiologically difficult airway and obese and pregnant patient populations.</p>","PeriodicalId":10325,"journal":{"name":"Clinical and Experimental Emergency Medicine","volume":" ","pages":"136-144"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11237254/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139575290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Attending physicians as simulation learners: summary of current practices and barriers in emergency medicine. 作为模拟学习者的主治医生:急诊医学当前实践与障碍总结》。
IF 1.9
Clinical and Experimental Emergency Medicine Pub Date : 2024-06-01 Epub Date: 2024-01-29 DOI: 10.15441/ceem.23.137
Sara Margaret Hock, Michael Cassara, Amish Aghera, David Saloum, Suzanne Kathleen Bentley
{"title":"Attending physicians as simulation learners: summary of current practices and barriers in emergency medicine.","authors":"Sara Margaret Hock, Michael Cassara, Amish Aghera, David Saloum, Suzanne Kathleen Bentley","doi":"10.15441/ceem.23.137","DOIUrl":"10.15441/ceem.23.137","url":null,"abstract":"","PeriodicalId":10325,"journal":{"name":"Clinical and Experimental Emergency Medicine","volume":" ","pages":"224-228"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11237257/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139575120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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