Chonnam Medical Journal最新文献_第4页

Platelet Indices as Diagnostic Marker for Kawasaki Disease. 血小板指标作为川崎病的诊断指标。

Chonnam Medical Journal Pub Date : 2022-09-01 Epub Date: 2022-09-23 DOI: 10.4068/cmj.2022.58.3.110

Sung Hoon Kim, In Ji Hwang, Young Kuk Cho

{"title":"Platelet Indices as Diagnostic Marker for Kawasaki Disease.","authors":"Sung Hoon Kim, In Ji Hwang, Young Kuk Cho","doi":"10.4068/cmj.2022.58.3.110","DOIUrl":"https://doi.org/10.4068/cmj.2022.58.3.110","url":null,"abstract":"Various candidate biomarkers have been investigated for the early and accurate diagnosis of Kawasaki disease (KD). We aimed to evaluate platelet activity using platelet indices (PI) in patients with KD or simple febrile illness to determine whether these indices might support a diagnosis of KD. Another objective of the study was to delineate the changes in PI from the acute to convalescent phases of KD. A total of 225 patients with complete KD (cKD), 110 with incomplete KD (iKD), and 71 with simple febrile illness (control) were enrolled. PI included mean platelet volume (MPV), platelet distribution width (PDW), and plateletcrit (PCT). We serially measured the serum PI four times for each patient with KD from the acute to convalescent phases: on D0 (day of intravenous immunoglobulin (IVIG) treatment) and repeated on days 2 (D2), 14 (D14), and 56 (D56) after IVIG therapy. Data from the control group were collected during the acute stage of the disease (D0). The platelet counts in the cKD (341±103×103/mm3) and iKD (374±135×103/mm3) at diagnosis were higher than the control group (290±128×103/mm3). The PCT in the cKD (0.284±0.085%) and iKD (0.313±0.109%) groups at diagnosis were also higher than the control group (0.246±0.108%). However, the MPV and PDW levels in the KD group were not statistically significant. Therefore, platelet count and PCT are adjuvant parameters for the differential diagnosis of KD from a simple febrile illness.","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":"58 3","pages":"110-118"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/44/95/cmj-58-110.PMC9535102.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33513456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Association of Oxidative Stress and Reactive Oxygen Species Modulator 1 (ROMO1) with Infertility: A Mini Review. 氧化应激和活性氧调节剂1 (ROMO1)与不孕症的关系:综述。

Chonnam Medical Journal Pub Date : 2022-09-01 Epub Date: 2022-09-23 DOI: 10.4068/cmj.2022.58.3.91

Mohammad Amin Amini, Masoud Karimi, Seyed Saman Talebi, Hossein Piri, Jamshid Karimi

{"title":"The Association of Oxidative Stress and Reactive Oxygen Species Modulator 1 (ROMO1) with Infertility: A Mini Review.","authors":"Mohammad Amin Amini, Masoud Karimi, Seyed Saman Talebi, Hossein Piri, Jamshid Karimi","doi":"10.4068/cmj.2022.58.3.91","DOIUrl":"https://doi.org/10.4068/cmj.2022.58.3.91","url":null,"abstract":"Infertility is one of the disorders that worries many couples around the world, although novel and molecular methods can be used to cure this disease in different stages. One of the factors that causes infertility in men and women is the increased oxidative stress within the cells, which can lead to damage in zygote formation. ROMO1 is one of the most important proteins in the production of reactive oxygen species. This protein can enhance oxidative stress in the cells and body through cellular pathways, such as TNF-α and NF-κB routes, which will eventually lead to many diseases, especially infertility. We engage several international databases by using keywords; ROMO1, Infertility, and Reactive Oxygen Species, and gained a great quantity of information about ROMO1, Infertility, and Oxidative Stress. Although not proven, it is hypothesized that ROMO1 might elevate oxidative stress by activating NF-κB pathway in the cells, furthermore, TNF-α can arouse ROMO1 that can end up with apoptosis and cell death, which consequently can have a lot of disturbing effects on the body, especially the reproductive system. To sum up, revealing the exact cellular and molecular mechanisms of ROMO1-dependent TNF-α and NF-κB pathways in the pathogenesis of infertility might find interesting therapeutic and management strategies for this disorder.","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":"58 3","pages":"91-95"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d8/8d/cmj-58-91.PMC9535111.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33513461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

COVID-19 and the Human Gut Microbiome: An Under-Recognized Association. COVID-19和人类肠道微生物组:一个未被充分认识的联系。

Chonnam Medical Journal Pub Date : 2022-09-01 Epub Date: 2022-09-23 DOI: 10.4068/cmj.2022.58.3.96

Abu Fahad Abbasi, Aleksandra Marinkovic, Stephanie Prakash, Adekunle Sanyaolu, Stella Smith

{"title":"COVID-19 and the Human Gut Microbiome: An Under-Recognized Association.","authors":"Abu Fahad Abbasi, Aleksandra Marinkovic, Stephanie Prakash, Adekunle Sanyaolu, Stella Smith","doi":"10.4068/cmj.2022.58.3.96","DOIUrl":"https://doi.org/10.4068/cmj.2022.58.3.96","url":null,"abstract":"Coronavirus disease 2019 (COVID-19) is an infectious disease with a wide range of respiratory and extrapulmonary symptoms, as well as gastrointestinal symptoms. Despite recent research linking gut microbiota to infectious diseases like influenza, minimal information is known about the gut microbiota's function in COVID-19 pathogenesis. Studies suggest that dysbiosis of the gut microbiota and gut barrier dysfunction may play a role in COVID-19 pathogenesis by disrupting host immune homeostasis. Regardless of whether patients had taken medication or disease severity, the gut microbiota composition was significantly altered in COVID-19 patients compared to non-COVID-19 individuals. Several gut commensals with recognized immunomodulatory potential, such as Faecalibacterium prausnitzii, Eubacterium rectale, and bifidobacteria, were underrepresented in patients and remained low in samples taken several weeks after disease resolution. Furthermore, even with disease resolution, dysbiosis in the gut microbiota may contribute to chronic symptoms, underscoring the need to learn more about how gut microbes play a role in inflammation and COVID-19.","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":"58 3","pages":"96-101"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/12/a5/cmj-58-96.PMC9535107.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33513455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Gastric Mucosal Laceration due to Percutaneous Endoscopic Gastrostomy. 经皮内镜胃造口术致胃黏膜撕裂伤。

Chonnam Medical Journal Pub Date : 2022-09-01 Epub Date: 2022-09-23 DOI: 10.4068/cmj.2022.58.3.131

Yusaku Kajihara

引用次数: 0

Sclerosing Mesenteritis: "Fat Ring Sign". 硬化性肠系炎:“脂肪环征”。

Chonnam Medical Journal Pub Date : 2022-09-01 Epub Date: 2022-09-23 DOI: 10.4068/cmj.2022.58.3.135

Yusaku Kajihara

引用次数: 0

Symptomatic Expanding Cyst of the Septum Pellucidum. 有症状的透明隔扩张囊肿。

Chonnam Medical Journal Pub Date : 2022-09-01 Epub Date: 2022-09-23 DOI: 10.4068/cmj.2022.58.3.129

Keizo Tanitame, Nobuko Tanitame

{"title":"Symptomatic Expanding Cyst of the Septum Pellucidum.","authors":"Keizo Tanitame, Nobuko Tanitame","doi":"10.4068/cmj.2022.58.3.129","DOIUrl":"https://doi.org/10.4068/cmj.2022.58.3.129","url":null,"abstract":"https://doi.org/10.4068/cmj.2022.58.3.129 C Chonnam Medical Journal, 2022 Chonnam Med J 2022;58:129-130 Corresponding Author: Keizo Tanitame Department of Diagnostic Radiology, Araki Neurosurgical Hospital, 2-8-7 Kogokita, Nishi-ku, Hiroshima 733-0821, Japan Tel: +81-82-272-1114, Fax: +81-82-272-7048, E-mail: tntrad@gmail.com Article History: Received May 28, 2022 Revised June 19, 2022 Accepted June 21, 2022 FIG. 1. (A) Axial T2-weighted magnetic resonance (MR) image showed an expanding cyst of the septum pellucidum (CSP) with lateral bowing walls (arrows) and moderate dilation of the lateral ventricles. (B) Coronal T2-weighted MR image showed obstruction of both foramina of Monro (arrows) due to compression by the expanding CSP. (C) Sagittal T2-weighted MR image showed compression and thinning of the body of corpus callosum (arrows) and caudal displacement of the fornix (arrowhead). Symptomatic Expanding Cyst of the Septum Pellucidum Keizo Tanitame* and Nobuko Tanitame Department of Diagnostic Radiology, Araki Neurosurgical Hospital, Hiroshima, Department of Radiology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":"58 3","pages":"129-130"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d1/50/cmj-58-129.PMC9535105.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33513462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pseudo-Subarachnoid Hemorrhage on Computed Tomography after Resuscitation from Cardiopulmonary Arrest. 心肺骤停复苏后假性蛛网膜下腔出血的计算机断层扫描。

Chonnam Medical Journal Pub Date : 2022-09-01 Epub Date: 2022-09-23 DOI: 10.4068/cmj.2022.58.3.138

Keizo Tanitame, Nobuko Tanitame

{"title":"Pseudo-Subarachnoid Hemorrhage on Computed Tomography after Resuscitation from Cardiopulmonary Arrest.","authors":"Keizo Tanitame, Nobuko Tanitame","doi":"10.4068/cmj.2022.58.3.138","DOIUrl":"https://doi.org/10.4068/cmj.2022.58.3.138","url":null,"abstract":"https://doi.org/10.4068/cmj.2022.58.3.138 C Chonnam Medical Journal, 2022 Chonnam Med J 2022;58:138-139 Corresponding Author: Keizo Tanitame Department of Diagnostic Radiology, Araki Neurosurgical Hospital, 2-8-7 Kogokita, Nishi-ku, Hiroshima 733-0821, Japan Tel: +81-82-272-1114, Fax: +81-82-272-7048, E-mail: tntrad@gmail.com Article History: Received June 9, 2022 Revised June 25, 2022 Accepted June 29, 2022 FIG. 2. Non-contrast head CT on the second day revealed diffuse brain edema, loss of gray-white matter contrast, and increased attenuation of the subarachnoid spaces of the basal and Sylvian cisterns (arrows) and the sulci of the frontal lobes (arrowheads) with a mean CT value of 39.8 Hounsfield unit. FIG. 1. Non-contrast head computed tomography (CT) on admission revealed no abnormalities. Pseudo-Subarachnoid Hemorrhage on Computed Tomography after Resuscitation from Cardiopulmonary Arrest Keizo Tanitame* and Nobuko Tanitame Department of Diagnostic Radiology, Araki Neurosurgical Hospital, Department of Radiology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":"58 3","pages":"138-139"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7c/57/cmj-58-138.PMC9535106.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33513454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Renal Replacement Lipomatosis: A Rare and Often Ignored Entity 肾脏替代脂肪瘤病:一种罕见且常被忽视的疾病

Chonnam Medical Journal Pub Date : 2022-05-01 DOI: 10.4068/cmj.2022.58.2.81

Rashim Sharma, Sudeep Khera, M. Singh, Shakti Swarup Sarangi, Ismetara Begam

引用次数: 0

Predialysis Urea Nitrogen Is a Nutritional Marker of Hemodialysis Patients. 透析前尿素氮是血液透析患者的营养指标。

Chonnam Medical Journal Pub Date : 2022-05-01 DOI: 10.4068/cmj.2022.58.2.69

Seung Woo Lee, Yu Mi Yang, Hye-Young Kim, Hyunjeong Cho, Sang Won Nam, Sun Moon Kim, Soon Kil Kwon

{"title":"Predialysis Urea Nitrogen Is a Nutritional Marker of Hemodialysis Patients.","authors":"Seung Woo Lee, Yu Mi Yang, Hye-Young Kim, Hyunjeong Cho, Sang Won Nam, Sun Moon Kim, Soon Kil Kwon","doi":"10.4068/cmj.2022.58.2.69","DOIUrl":"https://doi.org/10.4068/cmj.2022.58.2.69","url":null,"abstract":"End-stage renal disease (ESRD) patients on hemodialysis have poor nutritional status and associated problems such as inflammation and sarcopenia. Blood urea nitrogen (BUN) is an important measure of uremic toxins, and urea reduction is a marker of hemodialysis efficacy. However, a low protein diet for lower BUN could aggravate malnutrition in patients, and optimal pre-dialysis BUN is not defined. We investigated the association of pre-dialysis BUN with patients' comorbidities and the relationship between pre-dialysis BUN and serum albumin as a nutrient marker. Among the 67 patients, the average pre- and post-dialysis BUN were 59.2 and 15.0 mg/dL, respectively, serum creatinine was 10.1 mg/dL, and the average serum albumin was 4.0 g/dL. Patients' age was negatively correlated with serum creatinine (r=-0.277, p<0.05) and albumin (r=-0.453, p<0.001). Predialysis BUN showed a significant positive correlation with serum albumin (r=0.287, p<0.05) and creatinine (r=0.454, p<0.001). However, the predialysis BUN was not significantly related to diabetes, coronary artery disease, congestive heart failure, or cerebrovascular disease. Hemodialysis patients with high pre-dialysis BUN and high serum creatinine could be regarded as having good nutritional status. The significance of this study lies in the potential utility of pre-dialysis blood urea nitrogen as an indicator of the nutritional status of patients. Liberal protein intake might be recommended to adequately dialyzed patients.","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":"58 2","pages":"69-74"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a3/4c/cmj-58-69.PMC9163601.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10252276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Ventricular Tachycardia Associated with Allium Species Intoxication 与葱属植物中毒有关的室性心动过速

Chonnam Medical Journal Pub Date : 2022-05-01 DOI: 10.4068/cmj.2022.58.2.88

Yi-Shik Kim, L. Jung, In-Jae Kim, K. Rhee

引用次数: 0