Chonnam Medical Journal最新文献

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A Rare Case of Acute Pancreatitis with Concomitant Ulcerative Colitis 急性胰腺炎并发溃疡性结肠炎1例
Chonnam Medical Journal Pub Date : 2022-05-01 DOI: 10.4068/cmj.2022.58.2.83
Kyoung-Hoon Yoo, K. Choi, Tae Hyeon Kim, H. Chon
{"title":"A Rare Case of Acute Pancreatitis with Concomitant Ulcerative Colitis","authors":"Kyoung-Hoon Yoo, K. Choi, Tae Hyeon Kim, H. Chon","doi":"10.4068/cmj.2022.58.2.83","DOIUrl":"https://doi.org/10.4068/cmj.2022.58.2.83","url":null,"abstract":"https://doi.org/10.4068/cmj.2022.58.2.83 C Chonnam Medical Journal, 2022 Chonnam Med J 2022;58:83-84 Corresponding Author: Hyung Ku Chon Department of Internal Medicine, Wonkwang University School of Medicine and Hospital, 895 Muwang-ro, Iksan 54538, Korea Tel: +82-63-859-2564, Fax: +82-63-855-2025, E-mail: gipb2592@wku.ac.kr Article History: Received February 19, 2022 Revised April 5, 2022 Accepted April 17, 2022 FIG. 1. Abdominal computed tomography reveals (A) diffuse edematous swelling of the pancreas, “sausage like” appearance of the pancreas with a low attenuating halo (white arrows) and (B) diffuse bowel wall thickening involving the rectum (open white arrow).","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":"14 4 1","pages":"83 - 84"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83537408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiation Ileitis Leading to Enterovesical Fistula 放射性回肠炎导致肠膀胱瘘
Chonnam Medical Journal Pub Date : 2022-05-01 DOI: 10.4068/cmj.2022.58.2.77
A. Hokama, Moemi Kanemoto, Keita Hagiwara, Akihito Ikemura, Erika Koga, Shigehito Tameda, Yuiko Oishi, Souhei Tabata, Kouya Miyazato, J. Fujita
{"title":"Radiation Ileitis Leading to Enterovesical Fistula","authors":"A. Hokama, Moemi Kanemoto, Keita Hagiwara, Akihito Ikemura, Erika Koga, Shigehito Tameda, Yuiko Oishi, Souhei Tabata, Kouya Miyazato, J. Fujita","doi":"10.4068/cmj.2022.58.2.77","DOIUrl":"https://doi.org/10.4068/cmj.2022.58.2.77","url":null,"abstract":"https://doi.org/10.4068/cmj.2022.58.2.77 C Chonnam Medical Journal, 2022 Chonnam Med J 2022;58:77-78 Corresponding Author: Akira Hokama Department of Endoscopy, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan Tel: +81-988951144, Fax: +81-988951414, E-mail: hokama-a@med.u-ryukyu.ac.jp Article History: Received January 16, 2022 Revised January 21, 2022 Accepted January 24, 2022 FIG. 1. A radiographic study using gastrographin showed the markedly stenotic ileum with ‘saw tooth’ appearance (arrow). FIG. 2. Cystography disclosed the enhancing material draining from the bladder (arrowhead) to the diseased ileum (arrow), consistent with the enterovesical fistula. Radiation Ileitis Leading to Enterovesical Fistula Akira Hokama*, Moemi Kanemoto, Keita Hagiwara, Akihito Ikemura, Erika Koga, Shigehito Tameda, Yuiko Oishi, Souhei Tabata, Kouya Miyazato, and Jiro Fujita Departments of Endoscopy and Infectious, Respiratory, and Digestive Medicine, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan,","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":"67 1","pages":"77 - 78"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84720457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Our Dedicated Effort to Save a COVID-19 Confirmed Patient with Myocardial Infarction 我们为拯救COVID-19确诊心肌梗死患者所做的不懈努力
Chonnam Medical Journal Pub Date : 2022-05-01 DOI: 10.4068/cmj.2022.58.2.85
S. Oh, Min Chul Kim, D. Sim, Y. Hong, Ju Han Kim, Youngkeun Ahn, M. Jeong
{"title":"Our Dedicated Effort to Save a COVID-19 Confirmed Patient with Myocardial Infarction","authors":"S. Oh, Min Chul Kim, D. Sim, Y. Hong, Ju Han Kim, Youngkeun Ahn, M. Jeong","doi":"10.4068/cmj.2022.58.2.85","DOIUrl":"https://doi.org/10.4068/cmj.2022.58.2.85","url":null,"abstract":"F IG . 1. During the hospitalization to the intensive care unit, ventricular fibrillation with sudden cardiac arrest occurred. After electrical defibrillation, the patient was successfully resusci-tated. A 73-year-old COVID-19 confirmed female was brought to our tertiary cardiovascular center because of acute myocardial infarction (AMI). Since cardiac arrest occurred with ventricular fibrillation (Fig. 1), an urgent coronary angiogram (CAG) was planned. Before CAG, all cathlab team members wore personal protective equipment (Fig. 2, Supplemental Video 1). CAG showed critical stenoses at both proximal and distal portions of left circumflex coronary artery (LCX) (Fig. 3A, Supplemental Video 2). After a 2.5×15 mm balloon was pre-dilated, we implanted two drug-eluting stents","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":"84 1","pages":"85 - 86"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73642814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Jejunal Arteriovenous Malformation Detected by Video Capsule Endoscopy 视频胶囊内镜检测空肠动静脉畸形
Chonnam Medical Journal Pub Date : 2022-05-01 DOI: 10.4068/cmj.2022.58.2.75
Atsushi Iraha, Y. Irei, T. Kinjo, Yuiko Oishi, T. Ohira, Tetsu Kinjo, A. Hokama, Noritake Kosuge, Naoki Wada, M. Takatsuki, J. Fujita
{"title":"Jejunal Arteriovenous Malformation Detected by Video Capsule Endoscopy","authors":"Atsushi Iraha, Y. Irei, T. Kinjo, Yuiko Oishi, T. Ohira, Tetsu Kinjo, A. Hokama, Noritake Kosuge, Naoki Wada, M. Takatsuki, J. Fujita","doi":"10.4068/cmj.2022.58.2.75","DOIUrl":"https://doi.org/10.4068/cmj.2022.58.2.75","url":null,"abstract":"A 61-year-old man visited a clinic because of melena. He had taken amlodipine for hypertension but no antiplatelet drugs. After esophagogastroduodenoscopy (EGD) and colonoscopy were negative, he was referred to our hospital for overt small bowel bleeding. A physical examination showed stable vital signs and","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":"49 1","pages":"75 - 76"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79030785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cutaneous Metastasis from Cholangiocarcinoma 胆管癌的皮肤转移
Chonnam Medical Journal Pub Date : 2022-05-01 DOI: 10.4068/cmj.2022.58.2.79
Y. Kajihara
{"title":"Cutaneous Metastasis from Cholangiocarcinoma","authors":"Y. Kajihara","doi":"10.4068/cmj.2022.58.2.79","DOIUrl":"https://doi.org/10.4068/cmj.2022.58.2.79","url":null,"abstract":"https://doi.org/10.4068/cmj.2022.58.2.79 C Chonnam Medical Journal, 2022 Chonnam Med J 2022;58:79-80 Corresponding Author: Yusaku Kajihara Department of Gastroenterology, Fuyoukai Murakami Hospital, 3-3-14 Hamada, Aomori 030-0843, Japan Tel: +81-17-729-8888, Fax: +81-17-729-8887, E-mail: yukajihara-gi@umin.ac.jp Article History: Received January 31, 2022 Revised February 8, 2022 Accepted February 9, 2022 FIG. 1. (A) An erythematous ulcerated nodule measuring 4×3 cm. (B) Histological evaluation (hematoxylin and eosin staining) revealing malignant glands in the subcutaneous area. FIG. 2. Computed tomography coronal view showing cholangiocarcinoma (arrows) and a liver metastasis (arrowheads). Cutaneous Metastasis from Cholangiocarcinoma","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":"24 1","pages":"79 - 80"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74753317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gold Threads on Chest Radiograph 胸片上的金线
Chonnam Medical Journal Pub Date : 2022-05-01 DOI: 10.4068/cmj.2022.58.2.87
Y. Kajihara
{"title":"Gold Threads on Chest Radiograph","authors":"Y. Kajihara","doi":"10.4068/cmj.2022.58.2.87","DOIUrl":"https://doi.org/10.4068/cmj.2022.58.2.87","url":null,"abstract":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/ by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. FIG. 1. Chest radiograph showing numerous short, hyper-dense, thread-like fragments in the chest and neck. FIG. 2. Computed tomography confirming multiple fine metallic subcutaneous densities. Gold Threads on Chest Radiograph","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":"36 1","pages":"87 - 87"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86766534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic Significance of the Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio in Neuroendocrine Carcinoma. 中性粒细胞-淋巴细胞比值和血小板-淋巴细胞比值在神经内分泌癌中的预后意义。
Chonnam Medical Journal Pub Date : 2022-01-01 Epub Date: 2022-01-25 DOI: 10.4068/cmj.2022.58.1.29
Hyeon-Jong Kim, Kang Han Lee, Hyun Jeong Shim, Eu Chang Hwang, Yoo-Duk Choi, Hyunjin Bang, Sang Hee Cho, Ik-Joo Chung, Jun Eul Hwang, Myung Ah Lee, Woo Kyun Bae
{"title":"Prognostic Significance of the Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio in Neuroendocrine Carcinoma.","authors":"Hyeon-Jong Kim,&nbsp;Kang Han Lee,&nbsp;Hyun Jeong Shim,&nbsp;Eu Chang Hwang,&nbsp;Yoo-Duk Choi,&nbsp;Hyunjin Bang,&nbsp;Sang Hee Cho,&nbsp;Ik-Joo Chung,&nbsp;Jun Eul Hwang,&nbsp;Myung Ah Lee,&nbsp;Woo Kyun Bae","doi":"10.4068/cmj.2022.58.1.29","DOIUrl":"https://doi.org/10.4068/cmj.2022.58.1.29","url":null,"abstract":"<p><p>Extra-pulmonary neuroendocrine carcinoma is a rare and aggressive cancer. Although several biological and histological markers have been suggested as prognostic factors for this cancer, the prognostic importance of systemic inflammatory markers, including the neutrophil-lymphocyte ratio and platelet-lymphocyte ratio, is unclear. This study aimed to evaluate the association between systemic inflammatory markers and the prognosis of extra-pulmonary neuroendocrine carcinoma. We retrospectively analyzed the clinical data of 85 patients with unresectable or metastatic extra-pulmonary neuroendocrine carcinoma who received platinum-based chemotherapy as first-line chemotherapy from August 2007 to November 2019. We used time-dependent receiver operating characteristic curve analysis to determine the cut-off values. The cut-off values for the neutrophil-lymphocyte ratio and platelet-lymphocyte ratio were 3.0 and 158.5, respectively. There was no significant difference in the Eastern Cooperative Oncology Group performance status score, Ki-67 index, or response to chemotherapy between groups. The high neutrophil-lymphocyte ratio group showed significantly worse overall survival (high vs. low, median 11.1 vs. 21.0 months, log-rank p=0.004) and shorter median progression-free survival, but the latter was not statistically significant. The high platelet-lymphocyte ratio group also showed significantly worse progression-free survival and overall survival than the low platelet-lymphocyte ratio group (high vs. low: median 5.6 vs. 9.8 months, log-rank p=0.047 and median 13.8 vs. 21.0 months, log-rank p=0.013, respectively). In multivariable analysis, a high neutrophil-lymphocyte ratio was an independent prognostic factor for overall survival. The neutrophil-lymphocyte ratio is a potent and readily available prognostic factor for extra-pulmonary neuroendocrine carcinoma.</p>","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":"58 1","pages":"29-36"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cb/a7/cmj-58-29.PMC8813653.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39634631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Riedel's Lobe of the Liver. 里德尔的肝叶。
Chonnam Medical Journal Pub Date : 2022-01-01 Epub Date: 2022-01-25 DOI: 10.4068/cmj.2022.58.1.50
Yusaku Kajihara
{"title":"Riedel's Lobe of the Liver.","authors":"Yusaku Kajihara","doi":"10.4068/cmj.2022.58.1.50","DOIUrl":"https://doi.org/10.4068/cmj.2022.58.1.50","url":null,"abstract":"https://doi.org/10.4068/cmj.2022.58.1.50 C Chonnam Medical Journal, 2022 Chonnam Med J 2022;58:50-51 Corresponding Author: Yusaku Kajihara Department of Gastroenterology, Fuyoukai Murakami Hospital, 3-3-14 Hamada, Aomori 030-0843, Japan Tel: +81-17-729-8888, Fax: +81-17-729-8887, E-mail: yukajihara-gi@umin.ac.jp Article History: Received January 28, 2021 Revised February 3, 2021 Accepted February 9, 2021 FIG. 1. Downward elongation of the liver (arrows), ending at the level of the iliac crest. FIG. 2. The transverse diameter and the greatest anteroposterior diameter on the level with the upper pole of the right kidney. Riedel’s Lobe of the Liver","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":"58 1","pages":"50-51"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0e/f3/cmj-58-50.PMC8813661.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39927425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Dominant Dystrophic Epidermolysis Bullosa with a Mutation in COL7A1 Confirmed by Diagnostic Exome Sequencing. 诊断外显子组测序证实COL7A1突变的显性营养不良大疱性表皮松解症。
Chonnam Medical Journal Pub Date : 2022-01-01 Epub Date: 2022-01-25 DOI: 10.4068/cmj.2022.58.1.66
Sang-Hyeon Won, Kyung-Nam Bae, Jin-Hwa Son, Kihyuk Shin, Hoon-Soo Kim, Hyun-Chang Ko, Byung-Soo Kim, Moon-Bum Kim
{"title":"Dominant Dystrophic Epidermolysis Bullosa with a Mutation in <i>COL7A1</i> Confirmed by Diagnostic Exome Sequencing.","authors":"Sang-Hyeon Won,&nbsp;Kyung-Nam Bae,&nbsp;Jin-Hwa Son,&nbsp;Kihyuk Shin,&nbsp;Hoon-Soo Kim,&nbsp;Hyun-Chang Ko,&nbsp;Byung-Soo Kim,&nbsp;Moon-Bum Kim","doi":"10.4068/cmj.2022.58.1.66","DOIUrl":"https://doi.org/10.4068/cmj.2022.58.1.66","url":null,"abstract":"https://doi.org/10.4068/cmj.2022.58.1.66 C Chonnam Medical Journal, 2022 Chonnam Med J 2022;58:66-67 Corresponding Author: Moon-Bum Kim Department of Dermatology, Pusan National University Hospital, 179 Gudeok-ro, Seo-gu, Busan 49241, Korea Tel: +82-51-240-7338, Fax: +82-51-245-9467, E-mail: drkmp@hanmail.net Article History: Received November 10, 2021 Revised December 14, 2021 Accepted December 15, 2021 FIG. 1. Erythematous to purpuric scarring and milia on both lower legs, elbows, and the dorsa of hands and feet (A-E). Nail dystrophy on both fingernails and toenails (D, E). Dominant Dystrophic Epidermolysis Bullosa with a Mutation in COL7A1 Confirmed by Diagnostic Exome Sequencing Sang-Hyeon Won, Kyung-Nam Bae, Jin-Hwa Son, Kihyuk Shin, Hoon-Soo Kim, Hyun-Chang Ko, Byung-Soo Kim, and Moon-Bum Kim* Department of Dermatology, School of Medicine, Pusan National University, Biomedical Research Institute, Pusan National University Hospital, Busan, Korea","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":"58 1","pages":"66-67"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d7/6a/cmj-58-66.PMC8813656.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39927433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of Histone Acetylation in Mesenchymal Stem Cell Differentiation. 组蛋白乙酰化在间充质干细胞分化中的作用。
Chonnam Medical Journal Pub Date : 2022-01-01 Epub Date: 2022-01-25 DOI: 10.4068/cmj.2022.58.1.6
Sujeong Jang, Jinsu Hwang, Han-Seong Jeong
{"title":"The Role of Histone Acetylation in Mesenchymal Stem Cell Differentiation.","authors":"Sujeong Jang,&nbsp;Jinsu Hwang,&nbsp;Han-Seong Jeong","doi":"10.4068/cmj.2022.58.1.6","DOIUrl":"https://doi.org/10.4068/cmj.2022.58.1.6","url":null,"abstract":"<p><p>The mechanism and action concerning epigenetic modifications, especially that of histone modifications, are not fully understood. However, it is clear that histone modifications play an essential role in several biological processes that are involved in cell proliferation and differentiation. In this article, we focused on how histone acetylation may result in differentiation into mesenchymal stem cells as well as histone acetylation function. Moreover, histone acetylation followed by the action of histone deacetylase inhibitors, which can result in the differentiation of stem cells into other types of cells such as adipocytes, chondrocytes, osteocytes, neurons, and other lineages, were also reviewed.</p>","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":"58 1","pages":"6-12"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4d/f2/cmj-58-6.PMC8813658.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39634627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
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