Chonnam Medical Journal最新文献

Vomiting Associated with Rapid Weight Loss. 呕吐与体重迅速减轻有关。

Chonnam Medical Journal Pub Date : 2023-05-01 DOI: 10.4068/cmj.2023.59.2.140

Yusaku Kajihara

引用次数: 0

Adverse Effects Associated with Long-Term Use of Proton Pump Inhibitors. 长期使用质子泵抑制剂的不良反应。

Chonnam Medical Journal Pub Date : 2023-05-01 DOI: 10.4068/cmj.2023.59.2.115

Naina Mohamed Pakkir Maideen

{"title":"Adverse Effects Associated with Long-Term Use of Proton Pump Inhibitors.","authors":"Naina Mohamed Pakkir Maideen","doi":"10.4068/cmj.2023.59.2.115","DOIUrl":"https://doi.org/10.4068/cmj.2023.59.2.115","url":null,"abstract":"Proton Pump Inhibitors are used widely to manage many gastric acid-related conditions such as gastroesophageal disease, gastritis, esophagitis, Barrett's esophagus, Zollinger-Ellison syndrome, peptic ulcer disease, nonsteroidal anti-inflammatory drug-associated ulcers, and Helicobacter pylori eradication, around the globe. This review article focuses on adverse effects associated with the long-term use of proton pump inhibitors. Various observational studies, clinical trials, and meta-analyses have established the adverse effects associated with the long-term use of proton pump inhibitors including renal disorders (acute interstitial nephritis, acute kidney injury, chronic kidney disease, and end-stage renal disease), cardiovascular risks (major adverse cardiovascular events, myocardial infarction, stent thrombosis, and stroke), fractures, infections (Clostridium difficile infection, community-acquired pneumonia, and Coronavirus disease 2019), micronutrient deficiencies (hypomagnesemia, anemia, vitamin B12 deficiency, hypocalcemia, hypokalemia), hypergastrinemia, cancers (gastric cancer, pancreatic cancer, colorectal cancer, hepatic cancer), hepatic encephalopathy, and dementia. Clinicians including prescribers and pharmacists should be aware of the adverse effects of taking proton pump inhibitors for an extended period of time. In addition, the patients taking proton pump inhibitors for long-term should be monitored for the listed adverse effects. The American Gastroenterological association recommends a few non-pharmacological measures and the use of histamine 2 blockers to lessen gastrointestinal symptoms of gastroesophageal reflex disease and the utilization of proton pump inhibitors treatment if there is a definitive indication. Additionally, the American Gastroenterological association's Best Practice Advice statements emphasize deprescribing when there is no clear indication for proton pump inhibitors therapy.","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/be/8a/cmj-59-115.PMC10248387.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9623206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Gender Differences in the Risk of Depression in Community-Dwelling Stroke Survivors Compared to the General Population without Stroke. 社区中风幸存者与普通人群相比，抑郁风险的性别差异

Chonnam Medical Journal Pub Date : 2023-05-01 DOI: 10.4068/cmj.2023.59.2.134

Mina Kim, Young-Hoon Lee

{"title":"Gender Differences in the Risk of Depression in Community-Dwelling Stroke Survivors Compared to the General Population without Stroke.","authors":"Mina Kim, Young-Hoon Lee","doi":"10.4068/cmj.2023.59.2.134","DOIUrl":"https://doi.org/10.4068/cmj.2023.59.2.134","url":null,"abstract":"This study examined the gender-specific association between stroke status and depression in South Korea. A total of 5,746 men and 7,608 women aged ≥30 years who participated in the 2014, 2016, and 2018 Korea National Health and Nutrition Examination Survey were included in the analysis. The cross-sectional surveys targeted the general population consisting of nationally representative adults (≥19 years) residing in Korea. A 9-item Patient Health Questionnaire score of 10 or more was regarded as depression. A higher risk of depression in stroke survivors compared to the non-stroke population was not observed in men (odds ratio [OR], 1.51; 95% confidence intervals [CI], 0.82-2.81), while it was observed in women (OR, 2.49; 95% CI, 1.64-3.77). Compared to non-stroke women, women stroke survivors with a younger age at diagnosis (<60 years) (OR, 4.05; 95% CI, 2.28-7.20) and stroke with duration of ≥10 years (OR, 3.12; 95% CI, 1.63-5.97) had a higher risk for depression. Gender aspects should be more intensively considered in the association between stroke status and depression in community settings.","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d1/3e/cmj-59-134.PMC10248390.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9623211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Urban-Rural Differences in the Prevalence of Depressive Symptoms in Korean Adults. 韩国成年人抑郁症状患病率的城乡差异

Chonnam Medical Journal Pub Date : 2023-05-01 DOI: 10.4068/cmj.2023.59.2.128

Ji-An Jeong, Sun A Kim, Jung Ho Yang, Min-Ho Shin

{"title":"Urban-Rural Differences in the Prevalence of Depressive Symptoms in Korean Adults.","authors":"Ji-An Jeong, Sun A Kim, Jung Ho Yang, Min-Ho Shin","doi":"10.4068/cmj.2023.59.2.128","DOIUrl":"https://doi.org/10.4068/cmj.2023.59.2.128","url":null,"abstract":"This study aimed to investigate the prevalence of depression among Koreans living in urban and rural areas, stratified by socioeconomic status. The study included 216,765 participants from the 2017 Korean Community Health Survey. Depressive symptoms were assessed using the PHQ-9, with a score of 10 or higher indicating depressive symptoms. Residences with the words Eup and Myeon in their addresses were categorized as rural areas, and residences with Dong in their addresses as urban areas. Socioeconomic status was evaluated by household income and education level. A Poisson regression analysis with sampling weights was conducted and adjusted for demographic, lifestyle, socioeconomic status, and comorbidity. The adjusted prevalence rate of depressive symptoms was 3.33% (95% CI, 3.21-3.45) in urban areas and 2.59% (95% CI, 2.43-2.74) in rural areas. The prevalence of depressive symptoms in urban areas was 1.29 times (95% CI, 1.20-1.38) higher than in rural areas. The prevalence rate ratio for depressive symptoms in urban areas compared to rural areas sorted by monthly incomes was 1.39 (95% CI, 1.28-1.51) for less than 2 million won, 1.22 (95% CI, 1.06-1.41) for 2 to 3.99 million won, and 1.09 (95% CI, 0.90-1.32) for more than 4 million won, and the urban-rural difference was more evident in lower household income subjects (p for interaction=0.033). However, urban-rural differences did not differ according to sex, age, or education level. In conclusion, we found urban-rural differences in depressive symptoms in a representative sample of Koreans, and revealed that these differences may vary according to income level. These results suggest that mental health policy must consider the health disparities according to residence and income.","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c2/40/cmj-59-128.PMC10248393.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9617596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Superior Sagittal Sinus Thrombosis in Chronic Liver Disease. 慢性肝病的上矢状窦血栓形成。

Chonnam Medical Journal Pub Date : 2023-05-01 DOI: 10.4068/cmj.2023.59.2.141

Preet Mukesh Shah

引用次数: 0

Epiphrenic Esophageal Diverticulum. 食管急性憩室。

Chonnam Medical Journal Pub Date : 2023-05-01 DOI: 10.4068/cmj.2023.59.2.142

Akira Hokama, Yoriyuki Shimazaki, Jun Fukuchi, Maki Nishizawa

引用次数: 0

Diabetic Pedal Osteomyelitis and Its Treatment. 糖尿病足部骨髓炎及其治疗。

Chonnam Medical Journal Pub Date : 2023-05-01 DOI: 10.4068/cmj.2023.59.2.109

Vidyaalakshmi Venkatesan, Jayakumar Rangasamy

引用次数: 1

Injuries and Illness during the 2019 Gwangju FINA and Masters World Championships in Elite and Amateur Athletes. 2019年光州国际泳联和精英和业余运动员大师世界锦标赛期间的伤病。

Chonnam Medical Journal Pub Date : 2023-01-01 DOI: 10.4068/cmj.2023.59.1.83

Hee-Seung Henry Bom, Yong Hoon Jeong, Soohyung Cho

{"title":"Injuries and Illness during the 2019 Gwangju FINA and Masters World Championships in Elite and Amateur Athletes.","authors":"Hee-Seung Henry Bom, Yong Hoon Jeong, Soohyung Cho","doi":"10.4068/cmj.2023.59.1.83","DOIUrl":"https://doi.org/10.4068/cmj.2023.59.1.83","url":null,"abstract":"Comparative analysis of injury and illness prevalence in elite and amateur athletes provides the basis for the development of tailored prevention programs. The authors analyzed the differences in frequency and characteristics of injuries and illnesses which occurred in elite and amateur athletes during the 2019 Gwangju Federation Internationale de Natation (FINA) and Masters World Championships. The 2019 FINA World Championships hosted 3095 athletes in the disciplines of swimming, diving, high diving, artistic swimming, water polo, and open water swimming. While the 2019 Masters World Championships hosted 4032 athletes in swimming, diving, artistic swimming, water polo, and open water swimming. All medical records were electrically recorded in every venue as well as the central medical center located at the athlete's village. More elite athletes visited clinics than amateur athletes during the events (15.0 vs 8.6%, p<0.05) despite the ages of amateur athletes being higher than elite athletes (41.0±15.0 vs 22.4±5.6 years, p<0.01). Elite athletes complained mainly of musculoskeletal problems (69%), while amateur athletes complained of both musculoskeletal (38%) and cardiovascular (8%) problems. The most frequent injury in elite athletes was due to overuse in the shoulder joints, while that of amateur athletes was traumatic injuries involving feet and hands. The most common illness was respiratory infection in both elite and amateur athletes, while cardiovascular events occured only in amateur athletes. As the risk of injury varies in elite and amateur athletes, tailored preventive measures should be prepared. Furthermore, preventive measures of cardiovascular events should focus on amateur sports events.","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/09/9b/cmj-59-83.PMC9900224.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10795184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Benefits of Adjuvant Chemotherapy for Clinical T3-4N0 Rectal Cancer After Preoperative Chemoradiotherapy. 临床T3-4N0直肠癌术前放化疗后辅助化疗的益处

Chonnam Medical Journal Pub Date : 2023-01-01 DOI: 10.4068/cmj.2023.59.1.76

Hyun Jin Bang, Hyun Jeong Shim, Jun Eul Hwang, Woo Kyun Bae, Ik Joo Chung, Sang Hee Cho

{"title":"Benefits of Adjuvant Chemotherapy for Clinical T3-4N0 Rectal Cancer After Preoperative Chemoradiotherapy.","authors":"Hyun Jin Bang, Hyun Jeong Shim, Jun Eul Hwang, Woo Kyun Bae, Ik Joo Chung, Sang Hee Cho","doi":"10.4068/cmj.2023.59.1.76","DOIUrl":"https://doi.org/10.4068/cmj.2023.59.1.76","url":null,"abstract":"While the guidelines for adjuvant chemotherapy (AC) for colon cancer are relatively standardized, those for early rectal cancer are still lacking. We therefore evaluated the role of AC in clinical stage II rectal cancer treatment after preoperative chemoradiotherapy (CRT). Patients diagnosed with early rectal cancer (defined by clinical stage T3/4, N0) who completed CRT followed by surgery were enrolled in this retrospective study. To evaluate the role of AC, we analyzed the risk of recurrence and survival based on clinicopathologic parameters and adjuvant chemotherapy. Of the 112 patients, 11 patients (9.8%) experienced recurrence and five patients (4.8%) died. In a multivariate analysis, circumferential resection margin involvement (CRM+) on magnetic resonance imaging at diagnosis, CRM involvement following neoadjuvant therapy (ypCRM+), tumor regression grade (≤G1) and no-AC were considered poor prognostic factors for recurrence free survival (RFS). In addition, ypCRM+ and no-AC were associated with poor overall survival (OS) in the multivariate analysis. AC including 5-FU monotherapy demonstrated the benefits of reduced recurrence and prolonged survival in clinical stage II rectal cancer, even in pathologic stage following neoadjuvant therapy (ypStage) 0-I. Further prospective studies are needed to verify the benefit of each regimen of AC and the development of a method that can accurately predict CRM status before surgery, and a vigorous treatment that can induce CRM non-involvement (CRM-) should be considered even in early stages of rectal cancer.","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/14/14/cmj-59-76.PMC9900219.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10795187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Esophageal Rupture Due to Unexpected Sengstaken-Blakemore Tube Placement. 意外置入Sengstaken-Blakemore管导致食管破裂。

Chonnam Medical Journal Pub Date : 2023-01-01 DOI: 10.4068/cmj.2023.59.1.102

Koichi Soga

引用次数: 0