Chonnam Medical Journal最新文献_第2页

Predictors of Progression of Tricuspid Regurgitation in Patients with Persistent Atrial Fibrillation. 持续性心房颤动患者三尖瓣反流进展的预测因素。

Chonnam Medical Journal Pub Date : 2023-01-01 DOI: 10.4068/cmj.2023.59.1.70

Jiyeon Song, Jae Yeong Cho, Kye Hun Kim, Ga Hui Choi, Nuri Lee, Hyung Yoon Kim, Hyukjin Park, Hyun Ju Yoon, Ju Han Kim, Youngkeun Ahn, Myung Ho Jeong, Jeong Gwan Cho

{"title":"Predictors of Progression of Tricuspid Regurgitation in Patients with Persistent Atrial Fibrillation.","authors":"Jiyeon Song, Jae Yeong Cho, Kye Hun Kim, Ga Hui Choi, Nuri Lee, Hyung Yoon Kim, Hyukjin Park, Hyun Ju Yoon, Ju Han Kim, Youngkeun Ahn, Myung Ho Jeong, Jeong Gwan Cho","doi":"10.4068/cmj.2023.59.1.70","DOIUrl":"https://doi.org/10.4068/cmj.2023.59.1.70","url":null,"abstract":"Previous studies have shown that tricuspid regurgitation (TR) can be developed in patients with atrial fibrillation (AF) due to annular dilatation. This study aimed to investigate the incidence and predictors of the progression of TR in patients with persistent AF. A total of 397 patients (66.9±11.4 years, 247 men; 62.2%) with persistent AF were enrolled between 2006 and 2016 in a tertiary hospital, and 287 eligible patients with follow-up echocardiography were analyzed. They were divided into two groups according to TR progression (progression group [n=68, 70.1±10.7 years, 48.5% men] vs. non-progression group [n=219, 66.0±11.3 years, 64.8% men]). Among 287 patients in the analysis, 68 had worsening TR severity (23.7%). Patients in the TR progression group were older and more likely to be female. Patients with left ventricular ejection fraction <50% were less frequent in the progression group than those in the non-progression group (7.4% vs. 19.6%, p=0.018). Patients with mitral valve disease were more frequent in the progression group. Multivariate analysis with COX regression demonstrated independent predictors of TR progression, including left atrial (LA) diameter >54 mm (HR 4.85, 95%CI 2.23-10.57, p<0.001), E/e' (HR 1.05, 95%CI 1.01-1.10, p=0.027), and no use of antiarrhythmic agents (HR 2.20, 95%CI 1.03-4.72, p=0.041). In patients with persistent AF, worsening TR was not uncommon. The independent predictors of TR progression turned out to be greater LA diameter, higher E/e', and no use of antiarrhythmic agents.","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":"59 1","pages":"70-75"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ee/74/cmj-59-70.PMC9900221.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10739339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Promoting Psychosocial Health of Family Caregivers of Patients with Chronic Mental Disorders: A Review of Challenges and Strategies. 促进慢性精神障碍患者家庭照顾者的心理社会健康:挑战与策略综述

Chonnam Medical Journal Pub Date : 2023-01-01 DOI: 10.4068/cmj.2023.59.1.31

Fateme Lohrasbi, Mousa Alavi, Mohammad Akbari, Jahangir Maghsoudi

{"title":"Promoting Psychosocial Health of Family Caregivers of Patients with Chronic Mental Disorders: A Review of Challenges and Strategies.","authors":"Fateme Lohrasbi, Mousa Alavi, Mohammad Akbari, Jahangir Maghsoudi","doi":"10.4068/cmj.2023.59.1.31","DOIUrl":"https://doi.org/10.4068/cmj.2023.59.1.31","url":null,"abstract":"The present study aimed to investigate the mental and social health challenges of family caregivers of the patients with chronic mental disorders (CMD) and strategies which can be helpful in this regard. This study is a narrative review conducted in PubMed, Web of Science, Scopus, Elsevier, Google Scholar, Proquest, Magiran, and Sid databases where keywords such as Family caregiver, Chronic Mental disorder, Health Promotion, Program, Psychosocial, Support, Challenge, and Problem were searched in both Persian and English. A total of 5,745 published documents were found and were screened based on inclusion and exclusion criteria. Finally, 64 studies were found which had examined the related challenges, needs and strategies. According to the results, information deficits, needs for support, community participation deficits, and psychological suffering were recognized as challenges of family caregivers of these patients. Moreover, empowerments programs for the enhancement of the knowledge and skills of caregivers and peer-centered support programs were used to improve the level of mental and social health of family caregivers of these patients. Psychosocial problems and challenges that family caregivers of the patients with CMD face affect their health, satisfaction and quality of life. Using a collaborative approach, mental health service providers and government systems can help improve the psychosocial health of caregivers. The related managers and policymakers can reduce the emotional and psychological burden of families and promote their psychosocial health through developing a comprehensive program including practical objectives and strategies and taking into account the challenges that exist for caregivers in caring for patients with CMD.","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":"59 1","pages":"31-47"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/21/67/cmj-59-31.PMC9900218.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10739342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Magnetic Resonance Imaging and Spectroscopy of the Brain in MELAS Syndrome. MELAS综合征的脑磁共振成像和波谱。

Chonnam Medical Journal Pub Date : 2023-01-01 DOI: 10.4068/cmj.2023.59.1.100

Keizo Tanitame, Nobuko Tanitame

引用次数: 0

Protein-Caged Nanoparticles: A Promising Nanomedicine Against Cancer. 蛋白质笼化纳米粒子:一种很有前途的抗癌纳米药物。

Chonnam Medical Journal Pub Date : 2023-01-01 DOI: 10.4068/cmj.2023.59.1.1

Ayeskanta Mohanty, In-Kyu Park

引用次数: 0

Immune Response to COVID-19 Vaccination in Hematologic Malignancies: A Mini-Review. 血液恶性肿瘤患者对接种 COVID-19 疫苗的免疫反应：微型综述。

Chonnam Medical Journal Pub Date : 2023-01-01 Epub Date: 2023-01-25 DOI: 10.4068/cmj.2023.59.1.24

Samaneh Keshavarz, Somayeh Keshavarz, Nasrin Ziamajidi, Sajedeh Daei

引用次数: 0

Incidental Thrombus in Left Atrium Appendage Detected by Intracardiac Echocardiography. 心内超声心动图检测左心房附属物偶发血栓。

Chonnam Medical Journal Pub Date : 2023-01-01 DOI: 10.4068/cmj.2023.59.1.103

Sung Soo Kim, Hyung Ki Jeong, Jum Suk Ko

引用次数: 0

Impact of Comorbid Disease Burden on Clinical Outcomes of Female Acute Myocardial Infarction Patients. 合并症疾病负担对女性急性心肌梗死患者临床结局的影响

Chonnam Medical Journal Pub Date : 2023-01-01 DOI: 10.4068/cmj.2023.59.1.61

Jeong Shim Kim, Seok Oh, Myung Ho Jeong, Seok-Joon Sohn

{"title":"Impact of Comorbid Disease Burden on Clinical Outcomes of Female Acute Myocardial Infarction Patients.","authors":"Jeong Shim Kim, Seok Oh, Myung Ho Jeong, Seok-Joon Sohn","doi":"10.4068/cmj.2023.59.1.61","DOIUrl":"https://doi.org/10.4068/cmj.2023.59.1.61","url":null,"abstract":"Owing to the paucity of information on the clinical outcomes in female patients with acute myocardial infarction (AMI) in relation to the comorbid disease burden, we explored the differences in their clinical outcomes and identified predictive indicators. A total of 3,419 female AMI patients were stratified into two groups: Group A (those with zero or one comorbid diseases) (n=1,983) and Group B (those with two to five comorbid diseases) (n=1,436). Five comorbid conditions were considered: hypertension, diabetes mellitus, dyslipidemia, prior coronary artery disease, and prior cerebrovascular accidents. The primary outcome was major adverse cardiac and cerebrovascular events (MACCEs). The incidence of MACCEs was higher in Group B than in Group A in both the unadjusted and propensity score-matched data. Among the comorbid conditions, hypertension, diabetes mellitus, and prior coronary artery disease were found to be independently associated with an increased incidence of MACCEs. Higher comorbid disease burden was positively associated with adverse outcomes in the female population with AMI. Since both hypertension and diabetes mellitus are modifiable and independent predictors of adverse outcomes after AMI, it may be necessary to focus on the optimal management of blood pressure and glucose levels to improve cardiovascular outcomes.","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":"59 1","pages":"61-69"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2e/a7/cmj-59-61.PMC9900217.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10795188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dural Arteriovenous Fistula of the Cavernous Sinus. 海绵窦硬脑膜动静脉瘘

Chonnam Medical Journal Pub Date : 2023-01-01 Epub Date: 2023-01-25 DOI: 10.4068/cmj.2023.59.1.107

Keizo Tanitame, Hayato Araki, Shuichi Oki

引用次数: 0

Association between Decreased Estimated Glomerular Filtration Rates and Long-term Mortality in Korean Patients with Acute Myocardial Infarction. 韩国急性心肌梗死患者估计肾小球滤过率下降与长期死亡率之间的关系

Chonnam Medical Journal Pub Date : 2023-01-01 Epub Date: 2023-01-25 DOI: 10.4068/cmj.2023.59.1.87

Mi Sook Oh, Seong Woo Choi, Myung Ho Jeong, Eun Hui Bae, Jong Park, So Yeon Ryu, Mi Ah Han, Min Ho Shin

{"title":"Association between Decreased Estimated Glomerular Filtration Rates and Long-term Mortality in Korean Patients with Acute Myocardial Infarction.","authors":"Mi Sook Oh, Seong Woo Choi, Myung Ho Jeong, Eun Hui Bae, Jong Park, So Yeon Ryu, Mi Ah Han, Min Ho Shin","doi":"10.4068/cmj.2023.59.1.87","DOIUrl":"10.4068/cmj.2023.59.1.87","url":null,"abstract":"A reduced estimated glomerular filtration rate (eGFR) is a predictor for mortality in patients with acute myocardial infarction (AMI). This study aimed to compare mortality according to the GFR and eGFR calculation methods during long-term clinical follow-ups. Using the Korean Acute Myocardial Infarction Registry-National Institutes of Health Data, 13,021 patients with AMI were included in this study. Patients were divided into the surviving (n=11,503, 88.3%) and deceased (n=1,518, 11.7%) groups. Clinical characteristics, cardiovascular risk factors, and 3-year mortality-related factors were analyzed. eGFR was calculated using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) and Modification of Diet in Renal Disease (MDRD) equations. The surviving group was younger than the deceased group (62.6±12.4 vs. 73.6±10.5 years, p<0.001), whereas the deceased group had higher hypertension and diabetes prevalences than the surviving group. A high Killip class was more frequently observed in the deceased group. eGFR was significantly lower in the deceased group (82.2±24.1 vs. 55.2±28.6 ml/min/1.73 m2, p<0.001). Multivariate analysis revealed that low eGFR was an independent risk factor for mortality during the 3-year follow-up. The CKD-EPI equation was more useful for predicting mortality than the MDRD equation (0.766; 95% confidence interval [CI], 0.753-0.779 vs. 0.738; 95% CI, 0.724-0.753; p=0.001). Decreased renal function was a significant predictor of mortality after 3 years in patients with AMI. The CKD-EPI equation was more useful for predicting mortality than the MDRD equation.","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":"59 1","pages":"87-97"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6e/67/cmj-59-87.PMC9900226.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10739338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vitamins A, C, and E Exert Anti-apoptotic Function in the Testis of Rats After Exposure to Zinc Oxide Nanoparticles. 维生素A、C和E在氧化锌纳米颗粒暴露后大鼠睾丸中发挥抗凋亡功能。

Chonnam Medical Journal Pub Date : 2023-01-01 DOI: 10.4068/cmj.2023.59.1.48

Nasrin Ziamajidi, Sajedeh Daei, Maryam Khajvand-Abedini, Roghayeh Abbasalipourkabir, Alireza Nourian

{"title":"Vitamins A, C, and E Exert Anti-apoptotic Function in the Testis of Rats After Exposure to Zinc Oxide Nanoparticles.","authors":"Nasrin Ziamajidi, Sajedeh Daei, Maryam Khajvand-Abedini, Roghayeh Abbasalipourkabir, Alireza Nourian","doi":"10.4068/cmj.2023.59.1.48","DOIUrl":"https://doi.org/10.4068/cmj.2023.59.1.48","url":null,"abstract":"Some reports emphasize that zinc oxide nanoparticles (ZnO NPs) are detrimental to the reproductive organs of animals. As such, this research aimed at exploring the apoptotic potential of ZnO NPs on testis along with the beneficial role of Vitamins (V) A, C, and E against ZnO NP-induced damage. To this aim, a population of 54 healthy, male Wistar rats were used in this work and then assigned into nine groups of 6 rats as G1: Control 1 (Water); G2: Control 2 (Olive oil); G3: VA (1000 IU/kg), G4: VC (200 mg/kg), G5: VE (100 IU/kg), G6: ZnO NPs exposed animals (200 mg/kg); and G7, 8 and 9: ZnO NPs-exposed animals that were pre-treated with either VA, C, or E. Apoptosis rates were estimated by measuring the level of apoptotic regulatory markers including Bcl-2-associated X (Bax) and B-cell lymphoma protein 2 (Bcl-2) using western blotting and qRT-PCR assays. The data indicated that ZnO NPs exposure elevates the level of Bax protein and gene expression, whereas the protein and gene expression of Bcl-2 was reduced. Further, the activation of caspase-3,7 occurred after exposure to ZnO NPs, while the above alterations were significantly alleviated in the rats that were co-treated with VA, C, or E and ZnO NPs relative to the rats in the ZnO NPs group. In summary, VA, C, and E exerted anti-apoptotic functions in the testis of rats following administration of ZnO NPs.","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":"59 1","pages":"48-53"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/09/30/cmj-59-48.PMC9900230.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10795178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0