Fateme Lohrasbi, Mousa Alavi, Mohammad Akbari, Jahangir Maghsoudi
{"title":"Promoting Psychosocial Health of Family Caregivers of Patients with Chronic Mental Disorders: A Review of Challenges and Strategies.","authors":"Fateme Lohrasbi, Mousa Alavi, Mohammad Akbari, Jahangir Maghsoudi","doi":"10.4068/cmj.2023.59.1.31","DOIUrl":"https://doi.org/10.4068/cmj.2023.59.1.31","url":null,"abstract":"<p><p>The present study aimed to investigate the mental and social health challenges of family caregivers of the patients with chronic mental disorders (CMD) and strategies which can be helpful in this regard. This study is a narrative review conducted in PubMed, Web of Science, Scopus, Elsevier, Google Scholar, Proquest, Magiran, and Sid databases where keywords such as Family caregiver, Chronic Mental disorder, Health Promotion, Program, Psychosocial, Support, Challenge, and Problem were searched in both Persian and English. A total of 5,745 published documents were found and were screened based on inclusion and exclusion criteria. Finally, 64 studies were found which had examined the related challenges, needs and strategies. According to the results, information deficits, needs for support, community participation deficits, and psychological suffering were recognized as challenges of family caregivers of these patients. Moreover, empowerments programs for the enhancement of the knowledge and skills of caregivers and peer-centered support programs were used to improve the level of mental and social health of family caregivers of these patients. Psychosocial problems and challenges that family caregivers of the patients with CMD face affect their health, satisfaction and quality of life. Using a collaborative approach, mental health service providers and government systems can help improve the psychosocial health of caregivers. The related managers and policymakers can reduce the emotional and psychological burden of families and promote their psychosocial health through developing a comprehensive program including practical objectives and strategies and taking into account the challenges that exist for caregivers in caring for patients with CMD.</p>","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":"59 1","pages":"31-47"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/21/67/cmj-59-31.PMC9900218.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10739342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Esophageal Rupture Due to Unexpected Sengstaken-Blakemore Tube Placement.","authors":"Koichi Soga","doi":"10.4068/cmj.2023.59.1.102","DOIUrl":"https://doi.org/10.4068/cmj.2023.59.1.102","url":null,"abstract":"A 70-year-old Japanese man was hospitalized with type C cirrhosis. Following endoscopic variceal ligation (EVL) for esophageal varices (EV), esophagogastroduodenoscopy (EGD) was confirmed with multiple vascular telangiectasia and esophageal scars. The patient was admitted with mas-sive hematemesis and underwent an emergency EGD, which revealed EV bleeding. The endoscopic hemostasis procedures","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":"59 1","pages":"102"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/05/23/cmj-59-102.PMC9900229.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10795181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Magnetic Resonance Imaging and Spectroscopy of the Brain in MELAS Syndrome.","authors":"Keizo Tanitame, Nobuko Tanitame","doi":"10.4068/cmj.2023.59.1.100","DOIUrl":"https://doi.org/10.4068/cmj.2023.59.1.100","url":null,"abstract":",","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":"59 1","pages":"100-101"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/fc/c9/cmj-59-100.PMC9900216.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10739337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Protein-Caged Nanoparticles: A Promising Nanomedicine Against Cancer.","authors":"Ayeskanta Mohanty, In-Kyu Park","doi":"10.4068/cmj.2023.59.1.1","DOIUrl":"https://doi.org/10.4068/cmj.2023.59.1.1","url":null,"abstract":"Cancer is a severe threat to human wellness. A broad range of nanoparticles (NPs) have been developed to treat cancer. Given their safety profile, natural biomolecules such as protein-based NPs (PNPs) are promising substitutes for synthetic NPs that are currently used in drug delivery systems. In particular, PNPs have diverse characteristics and are monodisperse, chemically and genetically changeable, biodegradable, and biocompatible. To promote their application in clinical settings, PNPs must be precisely fabricated to fully exploit their advantages. This review highlights the different types of proteins that can be used to produce PNPs. Additionally, the recent applications of these nanomedicines and their therapeutic benefits against cancer are explored. Several future research directions that can facilitate the clinical application of PNPs are suggested.","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":"59 1","pages":"1-12"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9b/03/cmj-59-1.PMC9900222.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10739341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Immune Response to COVID-19 Vaccination in Hematologic Malignancies: A Mini-Review.","authors":"Samaneh Keshavarz, Somayeh Keshavarz, Nasrin Ziamajidi, Sajedeh Daei","doi":"10.4068/cmj.2023.59.1.24","DOIUrl":"10.4068/cmj.2023.59.1.24","url":null,"abstract":"<p><p>The outbreak of the COVID-19 infection has led to the rapidity of vaccine usage in recent years. Emerging data indicate that the efficacy of vaccination against COVID-19 was about 95% in the general population, though its impact is impaired in patients with hematologic malignancies. As such, we decided to research the publications in which the authors reported the impacts of COVID-19 vaccination in patients suffering from hematologic malignancies. We concluded that patients with hematologic malignancies have lower responses, antibody titers as well as an impaired humoral response following vaccination, notably in patients with chronic lymphocytic leukemia (CLL) and lymphoma. Furthermore, it seems that the status of treatment can significantly affect the responses to the COVID-19 vaccination.</p>","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":"59 1","pages":"24-30"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c2/32/cmj-59-24.PMC9900228.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10795179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Incidental Thrombus in Left Atrium Appendage Detected by Intracardiac Echocardiography.","authors":"Sung Soo Kim, Hyung Ki Jeong, Jum Suk Ko","doi":"10.4068/cmj.2023.59.1.103","DOIUrl":"https://doi.org/10.4068/cmj.2023.59.1.103","url":null,"abstract":"A 76-years-old woman visited the emergency department with exertional dyspnea. The electrocardiography rhythm showed atrial fibrillation (AF). Because the patient’s symptoms were severe, we performed direct current (DC) cardioversion after checking the transesophageal echocardiography (TEE,","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":"59 1","pages":"103-104"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8c/60/cmj-59-103.PMC9900223.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10795183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jeong Shim Kim, Seok Oh, Myung Ho Jeong, Seok-Joon Sohn
{"title":"Impact of Comorbid Disease Burden on Clinical Outcomes of Female Acute Myocardial Infarction Patients.","authors":"Jeong Shim Kim, Seok Oh, Myung Ho Jeong, Seok-Joon Sohn","doi":"10.4068/cmj.2023.59.1.61","DOIUrl":"https://doi.org/10.4068/cmj.2023.59.1.61","url":null,"abstract":"<p><p>Owing to the paucity of information on the clinical outcomes in female patients with acute myocardial infarction (AMI) in relation to the comorbid disease burden, we explored the differences in their clinical outcomes and identified predictive indicators. A total of 3,419 female AMI patients were stratified into two groups: Group A (those with zero or one comorbid diseases) (n=1,983) and Group B (those with two to five comorbid diseases) (n=1,436). Five comorbid conditions were considered: hypertension, diabetes mellitus, dyslipidemia, prior coronary artery disease, and prior cerebrovascular accidents. The primary outcome was major adverse cardiac and cerebrovascular events (MACCEs). The incidence of MACCEs was higher in Group B than in Group A in both the unadjusted and propensity score-matched data. Among the comorbid conditions, hypertension, diabetes mellitus, and prior coronary artery disease were found to be independently associated with an increased incidence of MACCEs. Higher comorbid disease burden was positively associated with adverse outcomes in the female population with AMI. Since both hypertension and diabetes mellitus are modifiable and independent predictors of adverse outcomes after AMI, it may be necessary to focus on the optimal management of blood pressure and glucose levels to improve cardiovascular outcomes.</p>","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":"59 1","pages":"61-69"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2e/a7/cmj-59-61.PMC9900217.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10795188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vitamins A, C, and E Exert Anti-apoptotic Function in the Testis of Rats After Exposure to Zinc Oxide Nanoparticles.","authors":"Nasrin Ziamajidi, Sajedeh Daei, Maryam Khajvand-Abedini, Roghayeh Abbasalipourkabir, Alireza Nourian","doi":"10.4068/cmj.2023.59.1.48","DOIUrl":"https://doi.org/10.4068/cmj.2023.59.1.48","url":null,"abstract":"<p><p>Some reports emphasize that zinc oxide nanoparticles (ZnO NPs) are detrimental to the reproductive organs of animals. As such, this research aimed at exploring the apoptotic potential of ZnO NPs on testis along with the beneficial role of Vitamins (V) A, C, and E against ZnO NP-induced damage. To this aim, a population of 54 healthy, male Wistar rats were used in this work and then assigned into nine groups of 6 rats as G1: Control 1 (Water); G2: Control 2 (Olive oil); G3: VA (1000 IU/kg), G4: VC (200 mg/kg), G5: VE (100 IU/kg), G6: ZnO NPs exposed animals (200 mg/kg); and G7, 8 and 9: ZnO NPs-exposed animals that were pre-treated with either VA, C, or E. Apoptosis rates were estimated by measuring the level of apoptotic regulatory markers including Bcl-2-associated X (Bax) and B-cell lymphoma protein 2 (Bcl-2) using western blotting and qRT-PCR assays. The data indicated that ZnO NPs exposure elevates the level of Bax protein and gene expression, whereas the protein and gene expression of Bcl-2 was reduced. Further, the activation of caspase-3,7 occurred after exposure to ZnO NPs, while the above alterations were significantly alleviated in the rats that were co-treated with VA, C, or E and ZnO NPs relative to the rats in the ZnO NPs group. In summary, VA, C, and E exerted anti-apoptotic functions in the testis of rats following administration of ZnO NPs.</p>","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":"59 1","pages":"48-53"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/09/30/cmj-59-48.PMC9900230.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10795178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hyun Kuk Kim, Sung Soo Kim, In Young Choi, Young Jae Ki, Keun Ho Park, Dong Hyun Choi
{"title":"Left Ventricular Free Wall Rupture Immediately following Successful Coronary Reperfusion Complicating ST Elevation Myocardial Infarction.","authors":"Hyun Kuk Kim, Sung Soo Kim, In Young Choi, Young Jae Ki, Keun Ho Park, Dong Hyun Choi","doi":"10.4068/cmj.2023.59.1.105","DOIUrl":"https://doi.org/10.4068/cmj.2023.59.1.105","url":null,"abstract":"https://doi.org/10.4068/cmj.2023.59.1.105 C Chonnam Medical Journal, 2023 Chonnam Med J 2023;59:105-106 Corresponding Author: Sung Soo Kim Department of Cardiovascular Medicine, Chosun University Medical School, Pilmun-daero, Dong-gu, Gwangju 62452, Korea Tel: +82-62-220-3240, Fax: +82-62-228-7174, E-mail: kholywater@gmail.com Article History: Received September 6, 2022 Revised September 21, 2022 Accepted September 24, 2022 FIG. 1. Initial 12-lead electrocardiography showing ST elevation and a Q wave in leads V1-V4 (arrow). Left Ventricular Free Wall Rupture Immediately following Successful Coronary Reperfusion Complicating ST Elevation Myocardial Infarction","PeriodicalId":10307,"journal":{"name":"Chonnam Medical Journal","volume":"59 1","pages":"105-106"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b1/27/cmj-59-105.PMC9900227.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10795180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}