中国实用眼科杂志最新文献

{"title":"Protective effect of progesterone on rat optic nerve after optic nerve crush","authors":"Hai-yan Sun, Wenting Sun, G. An","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.08.022","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.08.022","url":null,"abstract":"Objective \u0000To observe protective effect of progesterone on rat Optic Nerve after optic nerve crush. \u0000 \u0000 \u0000Methods \u0000Fifty female SD rats were randomly divided into three groups, normal group with 10 rats (20 eyes, the normal group had no treatment), control group with 20 rats and treatment group with 20 rats. Mis-classification damage analogues were made on control group and treated group. For the treatment group, progesterone was injected to the rats’ abdominal cavity (10mg/kg) after one hour of injury, for once a day and until the end of experiment. For the control group, distilled water was injected to the rats’ abdominal cavity (10mg/kg) after one hour of injury, for once a day and until the end of experiment. Four optic retinas of every group were taken. Fixed, embedded, sliced for HE staining to observe the morphological changes of the retina and detect the mean OD value of IGF-1 and AQP-4. \u0000 \u0000 \u0000Results \u0000The expression of IGF-1 in control group enhanced significantly after 1 day, 3 days and 7days of injury (P <0.05) and began to decrease at the 14th day.The expressions of IGF-1 in treatment group were significantly obvious than that of control group at every time point after injury and there was significant difference between the two group (P <0.05). The expression of AQP-4 in control group began to increase after one day of injury, reached the highest level at the third day, began to decrease at the 7th day and closed to normal level at the 28th day. Except for the 28th day the positive expressions of AQP-4 in treatment group at the first day, 3rd day, 7th day and 14th day were significantly lower than that of control. \u0000 \u0000 \u0000Conclusions \u0000The expression of IGF-1 and AQP-4 in normal retinal tissue is positive and it increases after incomplete injury of the optic nerve. IGF-1 and AQP-4 participate the process of incomplete injury of rats’ optic nerve. Progesterone can decrease the expression of AQP-4 and increase the expression of IGF-1 in the rat retinal tissue after the incomplete injury of optic nerve. Progesterone can promote the regeneration and repair of retina cell. \u0000 \u0000 \u0000Key words: \u0000Optic nerve; Progesterone; Retina ganglion cell; Insulin-like growth factor-1; Aquaporin-4","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":"31 1","pages":"836-840"},"PeriodicalIF":0.0,"publicationDate":"2017-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73503499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intravitreal conbercept injection for recurrent vitreous haemorrhage after diabetic vitrectomy","authors":"Pingli Zhu, Zhuoshi Wang, Liang-bao An, Ling-Xian Xu","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.08.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.08.006","url":null,"abstract":"Objective \u0000To assess the effects of intravitreal conbercept in treating delayed post-vitrectomy (4 weeks after surgery) diabetic vitreous hemorrhage (PVDVH). \u0000 \u0000 \u0000Methods \u0000Of 36 consecu-tive patients (36 eyes) with delayed PVDVH were assigned to tow groups, the study group (17 eyes) and the control group (19 eyes). The study group was treated with intravitreal conbercept, and repeated injection was given after 4 weeks in cases with no obvious blood absorption, until the blood was absorbed completely. The control group was given Chinese traditional medicine and iodized lecithin. The average follow-up duration was 8.5±2.5 months (ranged, 5~13 months). \u0000 \u0000 \u0000Results \u0000VCT of the study group was 2-8 weeks, mean 5.3±2.3 weeks, with average injection 2.2±0.8 times. Four eyes had developed recurrent vitreous hemorrhage (VH), but all of the eyes had a clear vitreous at the end of study period, and no vitrectomy surgery was needed. In the control group, eight eyes had spontaneous reabsorption in 3-9 weeks, mean 6.7±2.5 weeks, 11 eyes developed recurrent VH, the blood of one eye finally had been absorbed, 10 eyes had persistent VH, 4 eyes of them had iris neouvasculrization, and 4 eyes of them had retinal detachment, and finally these 10 eyes underwent revitrectomy surgeries. The vision of the study group was better than that in the control group. \u0000 \u0000 \u0000Conclusions \u0000Intravitreal conbercept treatment can accelerate the clear-up of the VH, reduce the complication and the need of revitrectomy for PVDVH. \u0000 \u0000 \u0000Key words: \u0000Conbercept; Diabetic retinopathy; Recurrent vitreous haemorrhage","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":"57 1","pages":"771-774"},"PeriodicalIF":0.0,"publicationDate":"2017-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72830397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical curative effect comparison of the iris localization and Kappa angle correction femtosecond LASIK","authors":"Q. Lin, Xuexi Li","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.08.014","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.08.014","url":null,"abstract":"Objective \u0000To compare the clinical curative effect of iris localization and Kappa Angle correction on femtosecond LASIK surgery. \u0000 \u0000 \u0000Methods \u0000Prospective randomized controlled study. Matching t test was used on two groups of postoperative 1 month visual acuity, contrast sensitivity respectively and preoperative best corrected visual acuity, best corrected vision wear glasses measuring contrast sensitivity. Two independent sample t test and nonparametric test were used on between the two groups of postoperative 1 month visual acuity, contrast sensitivity compared with preoperative best corrected visual acuity, best corrected vision wear glasses contrast sensitivity increased value and Pentacam measurement of cutting off center value pairs. Two groups of postoperative 1 month visual acuity, contrast sensitivity increased value with Pentacam measurement of cutting off center value, postoperative residual spherical mirror, l enticular mirror and cylindrical mirror axis for correlation analysis. \u0000 \u0000 \u0000Results \u0000Two groups of postoperative 1 month visual acuity, contrast sensitivity and preoperative best corrected visual acuity, best corrected vision wear glasses measuring contrast sensitivity difference was statistically significant. Between the two groups of postoperative 1 month visual acuity, contrast sensitivity and Pentacam measurement of cutting off center value differences had no statistical significance. \u0000 \u0000 \u0000Conclusions \u0000The two kinds of operation method can effectively avoid cutting off center of LASIK, get better than that of preoperative vision and contrast sensitivity. Two kinds of operation method postoperative visual acuity, contrast sensitivity increase value and cutting off center has no difference. \u0000 \u0000 \u0000Key words: \u0000Femtosecond laser; The iris localization; Kappa Angle correction","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":"143 1","pages":"808-812"},"PeriodicalIF":0.0,"publicationDate":"2017-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76965121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic effect of visual training on low vision of no amblyopia","authors":"Huade Wang, Qingsheng Zhang, Lan Shen, Erying Han, Lin Wei","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.08.021","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.08.021","url":null,"abstract":"Objective \u0000To investigate the therapeutic effect of visual training on low vision of no amblyopia. \u0000 \u0000 \u0000Methods \u0000A prospective study. A total of 56 children with low vision of no amblyopia were selected which came to Puyang Eye Hospital during a period from February 2015 to May 2016 to accept an visual training lasted for 4 weeks. All of the children met the following criteria: the degree of refractive power was-1.00 D~+3.00 D, without anisometropia, the discrepancy of corrected visual acuity of two eyes was less than two rows on standard visual acuity chart, the corrected visual acuity was below normal children, aged from 5 to 12 years old. The monocular corrected visual acuity, uncorrected visual acuity, monocular Flipper cycle and amplitude of monocular accommodation before and after the visual training were measured. \u0000 \u0000 \u0000Results \u0000The average binocular uncorrected visual acuity of the 56 children was 0.53±0.13 before training and was 0.91±0.14 after training, with statistical difference (t=3.2657, P <0.05). The average binocular corrected visual acuity was 0.59±0.12 before training and was 0.98±0.05 after training, with statistical difference (t=3.3724, P <0.05). The Flipper cycle of right eye before and after training respectively was 5.8±2.6 and 18.2±1.7, with statistical difference (t=13.6285, P <0.05). The Flipper cycle of left eye before and after training respectively was 6.3±1.9 and 18.5±1.3, with statistical difference (t=12.8354, P <0.05). The amplitude of accommodation of right eye was 8.9±2.5 D before training and was 15.1±1.2 D after training, with statistical difference (t=20.1624, P <0.05). The amplitude of accommodation of left eye was 8.6±2.2 D before training and was 15.3±1.1 D after training, with statistical difference (t=21.6218, P <0.05). \u0000 \u0000 \u0000Conclusions \u0000Visual training can effectively improve the adjust sensitivity and the amplitude of accommodation, uncorrected visual acuity and corrected visual acuity of low vision of no amblyopia. This suggests that the low vision of these patients is caused by dysfunction of accommodation. \u0000 \u0000 \u0000Key words: \u0000Visual training; Low vision; Amplitude of accommodation; Adjust sensitivity","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":"70 1","pages":"832-835"},"PeriodicalIF":0.0,"publicationDate":"2017-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83739458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical efficacy observation of Toric orthokeratology in myopic adolescent with moderate to high astigmatism for 1 year","authors":"Jiaying Wang, Chenhao Yang, Li Shen","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.08.013","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.08.013","url":null,"abstract":"Objective \u0000To observe the clinical efficacy of Toric design orthokeratology for myopia adolescents with moderate to high astigmatism. \u0000 \u0000 \u0000Methods \u0000A retrospective study. Twenty-four patients (40 eyes, Spherical group), were fitted with spherical orthokeratology lenses and 11 patients (18eyes, Toric group), were fitted with Toric design orthokeratology. Comparison of two groups 1 year eye axis of two different design orthokeratology. Patients fitted with Toric design orthokeratology lenses were measured uncorrected visual acuity (UCVA), corneal astigmatism and mean corneal curvature before lens wear and after wearing the lenses for 1 week, 1 month, 6 months, and 1 year. The relationship among the orthokeratology alignment zones curvature, flat K, corneal curvature with corneal diameter 5mm, 4mm place were analyzed. Date was analyzed with paired t test, independent samples t test and one-way ANOVA. \u0000 \u0000 \u0000Results \u0000After I year, AL increased by 0.25±0.14 (mm), 0.23±0.28 (mm) in the Spherical group and Toric group, indicating a statistically significant difference compared with those lens wear (t=-10.868, P 0.05). The uncorrected visual acuity (UCVA) had a statistically significant difference compared with UCVA before lens wear (F=83.185, P 0.05). Average corneal curvature had a statistically significant difference before and after lens wear (P 0.05), while had statistically significant difference with 5mm corneal diameter curvature (P <0.05). \u0000 \u0000 \u0000Conclusions \u0000Toric design and spherical design orthokeratology have similar effects in AL control with adolescents. Toric design orthokeratology can be fitted on myopic patients with moderate-to-high corneal astigmatism, and can improve the UCVA, reduce the corneal curvature, effectively and safely. \u0000 \u0000 \u0000Key words: \u0000Toric design Othokeratology; Corneal astigmatism; Myopia; Axial length","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":"51 1","pages":"803-807"},"PeriodicalIF":0.0,"publicationDate":"2017-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78901272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intravitreal Bevacizumab treatment for branch retinal vein occlusion accompanied by macular edema","authors":"Xian-li Zhuang, Haoyu Wang, Lin Zhao, Bing-zhen Li, K. Feng","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.08.005","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.08.005","url":null,"abstract":"Objective \u0000To compare the efficacy of intravitreal bevacizumab (IVB) in the treatment of macular edema, with or without foveal hemorrhage within the foveal cystoid apaces, subretinal hemorrhage (SRH) and serous retinal detachment (SRD) resulting from branch retinal vein occlusion (BRVO). \u0000 \u0000 \u0000Methods \u0000A retrospective review of 33 consecutive patients (33 eyes) was conducted with ME caused by acute BRVO. All patients received a comprehensive ophthalmologic examination, including measurement of best-corrected visual acuity (BCVA), measurement of intraocular pressure, slit-lamp biomicroscopy, color fundus photograghy, fluorescein angiography, and spectral domain optical coherence tomography (SD-OCT). Using hemorrhage within the foveal cystoid apaces, subretinal hemorrhage (SRH) and serous retinal detachment (SRD) three factors, the multiple logistic model were developed. \u0000 \u0000 \u0000Results \u0000Foveal SRH was closely correlated with BCVA. Patients were classified into one of two groups depending on whether or not foveal SRH was detected at the initial visit, BCVA and central macular thickness (CMT) were observed. After 6 months, SD-OCT revealed serous reti-nal detachments in the fovea of 15 eyes, 10 of which had accompanying foveal SRH. Based on initial detection of foveal SRH, patients were divided into SRH-negative (23 eyes) or SRH-positive (10 eyes) groups. Initial BCVA did not differ between the two groups. In the SRH-negative group, both BCVA and CMT improved significantly after IVB injections (mean, 2.3 injections) at the 6-months follow-up examination. In the SRH-positive group, there was no significant improvement in BCVA after IVB injections (mean, 2.0 injections), although there was a significant decrease in CMT. The final BCVA of the SRH-positive group was significantly poorer than that of the SRH-negative group (P=0.001). \u0000 \u0000 \u0000Conclusions \u0000The presence of foveal SRH may be a negative predictor of IVB treatment outcomes for BRVO patients with ME. \u0000 \u0000 \u0000Key words: \u0000Branch retinal vein occlusion; Hemorrhage within the foveal cystoid apaces; Serous retinal detachment; Subretinal hemorrhage; Macular edema; Bevacizumab","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":"16 1","pages":"767-770"},"PeriodicalIF":0.0,"publicationDate":"2017-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87460779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical correlation research of serum retinol binding protein 4 and type 2 diabetic retinopathy","authors":"Peng-wei Li","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.08.003","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.08.003","url":null,"abstract":"Objective \u0000To explore the relationship of serum retinol binding protein 4 (RBP4) with type 2 diabetic retinopathy. \u0000 \u0000 \u0000Methods \u0000Clinical case control study. The 83 cases of hospitalized pa-tients with type 2 diabetes mellitus (T2DM) were divided into three groups: PDR group (n =32 fun-dus examination showed proliferative diabetic retinopathy), NPDR group (n =20 fundus examination showed non proliferative diabetic retinopathy), NDR group (n =31 fundus examination showed nor-mal). Their serum RBP4 levels were measured. At the same time, factors that may be closely relat-ed to the occurrence and development of DR were detected. And we also measured the amplitude of B wave in full field electroretinogram (F-ERG). \u0000 \u0000 \u0000Results \u0000Serum RBP4 differences among three groups had statistical significance, P <0.05; There was significant difference in B wave amplitude among the three groups, P <0.05. Simple correlation analysis showed that the serum RBP4 level was negatively correlated with the b wave amplitude of ERG (r =-0.458, P =0.0001). Binary Logistic regres-sion analysis showed that RBP4 was significantly correlated with DR (B =0.105, P =0.019). \u0000 \u0000 \u0000Conclusions \u0000The increase of serum RBP4 level is consistent with the progress of DR. There is a close rela-tionship between serum RBP4 and the damage of retinal bipolar cells. \u0000 \u0000 \u0000Key words: \u0000Type 2 diabetes mellitus; Diabetic retinopathy; Retinol binding protein 4; Full-Field Electroretinograms","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":"37 1","pages":"760-763"},"PeriodicalIF":0.0,"publicationDate":"2017-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81557111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the size of YAG flare in implantable contact lens with intraocular lens implantation and peripheral iridectomy","authors":"Yong-Ming Shen, F. Zhu","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.08.018","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.08.018","url":null,"abstract":"Objective \u0000To compare the clinical significance of large and small spot YAG in Iridectomy before the Implantable Collamer Lens (ICL) implantation. \u0000 \u0000 \u0000Methods \u0000Seventy cases were randomly divided into group A and B, group A of 34 patients with large YAG spot iris peripheral laser (250um energy, the total energy 11-13mJ at the top 11 o’clock to 1 o’clock direction iris roots perforation of about 1×2mm) group B of 33 cases with small YAG spot iris peripheral laser (100um energy, the total energy 11-13mJ at the top 11 o’clock to 1 o’clock direction iris root perforation of about 1×2mm). Observation of intraocular pressure changes after laser surgery. \u0000 \u0000 \u0000Results \u0000Group A large spot and group B small spot get high intraocular pressure two hours later (Increased IOP 8 mmHg).There was no significant difference between the two groups, intraocular pressure increased 24 hours later (Increased intraocular pressure 8mmHg). \u0000 \u0000 \u0000Conclusions \u0000The small-spot YAG laser in the peripheral iridectomy produces iris depigmentation, causes inflammatory response, increase intraoc-ular pressure. The larger spot YAG laser iridotomy has advantages in hole forming of the iris peripheral edge, it has clinical significance to clinical iridal laser drilling, especially in patients with thicker iris stroma and more pigments. \u0000 \u0000 \u0000Key words: \u0000YAG laser; Peripheral iridectomy; Intraocular pressure","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":"63 1","pages":"823-824"},"PeriodicalIF":0.0,"publicationDate":"2017-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72478095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The application of anterior corneal stromal puncture combined with amniotic membrane patching in corneal diseases","authors":"Xiaofei Guo, F. Xiao","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.07.016","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.07.016","url":null,"abstract":"Objective \u0000To observe the clinical treatment of anterior corneal stromal puncture combined with amniotic membrane patching in bullous keratopathy and rsistent epithelial defects and recurrent corneal erosion. \u0000 \u0000 \u0000Methods \u0000Retrospective case series study. Analysis retrospectively the treatment of bullous keratopathy in 39 cases, 40 eyes in Tangshan ophthalmic hospital from January 2013 to January 2016 which implement anterior corneal stromal puncture combined with amniotic membrane patching. Among them, in 26 cases with bullous keratopathy in 26 eyes including 7 eyes with cataract surgery for glaucoma, 3 eyes with absolute glaucoma period, 5 eyes with vitrectomy, 6 eyes with ocular trauma, 5 eyes with neovascular glaucoma. In 8 cases with rsistent epithelial defects in 8 eyes including 4 eyes with acid burn, 4 eyes with alkali bum. In 5 cases with recurrent corneal erosion in 6 eyes including 2 eyes with Lattice malnutrition, 4 eyes with ocular trauma, 16 cases with patients of diabetes. All patients had obvious pain, tears irritation symptom. When the treatment was invalid after conservative therapy. The anterior corneal stromal puncture combined with amniotic membrane patching was carried out, to observe the eye irritation, corneal epithelial healing,edema of matrix and postoperative visual acuity, and so on. \u0000 \u0000 \u0000Results \u0000Forty eyes in 39 cases were relieved 3 days after the surgery, all patients had no pain and irritation symptoms after amniotic suture removal in 7-10 days. The corneal epithelium was repaired under the slit lamp microscope. One month the bullous keratopathy was recurrence after operation. In one eye which was cured with second anterior corneal stromal puncture. Follow up for 3-6 months, there were no recurrence of keratopathy, corneal epithelium was smooth, no edema, corneal stromal puncture area shallow layer to form a layer of uniform opacitas. The postoperative visual acuity: 22 eyes had no change before and after operation, 18 eyes improved partly. \u0000 \u0000 \u0000Conclusions \u0000The bullous keratopathy patients, resistant epithelial defects and recurrent corneal erosion caused by various factors are treated with anterior corneal stromal puncture combined with amniotic membrane patching, the eye symptom is obviously improved. Not only save the eyeball, but also improve vision on some of the eye. The anterior corneal stromal puncture combined with amniotic membrane patching is a simple, effective and reliable treatment method. \u0000 \u0000 \u0000Key words: \u0000Anterior corneal stromal puncture; Keratopathy; Amniotic membrane patching","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":"30 1","pages":"726-729"},"PeriodicalIF":0.0,"publicationDate":"2017-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73232445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The clinical significance of corneal protection to the ocular surface in strabismus surgery","authors":"M. Pan, Mei Yang, Ren-yi Xie, Huan He, Haiyan Wang","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.07.010","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.07.010","url":null,"abstract":"Objective \u0000To study the influence of corneal protection on the ocular surface and its clinical significance in strabismus surgery. \u0000 \u0000 \u0000Methods \u0000Strabismus patients aged from 7 to 45 years old were collected and divided into 3 groups according to the difference of corneal protection. At different time points, the first noninvasive tear film break-up time, average noninvasive tear film break-up time, and tear meniscus height were measured and the cornea fluorescein staining was evaluated. On the first day after surgery, the symptom of photophobia was observed. Finally, all the data were analyzed by statistics. \u0000 \u0000 \u0000Results \u0000The tear film break-up time wasn’t influenced by the surgery. Against other two groups,the occurrence rate of the symptom of photophobia and the positive cornea fluorescein staining were lower in the group B. The tear meniscus height of the group B increased little at 1 day after surgery and decreased to the preoperative level at one week after surgery. \u0000 \u0000 \u0000Conclusions \u0000Protecting the cornea in strabismus surgery by the 2% hydroxypropyl methycellulose can make patients more comfortable after operation.It’s simple and meaningful to do this during the surgery. \u0000 \u0000 \u0000Key words: \u0000Corneal protection; Strabismus surgery; The cornea fluorescein staining; Photophobia","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":"29 1","pages":"700-703"},"PeriodicalIF":0.0,"publicationDate":"2017-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89201114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}