Chronic Respiratory Disease最新文献

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Associations of sarcopenic obesity with chronic lung disease and peak expiratory flow in middle-aged and older adults: A cohort study based on CHARLS and ELSA. 中老年人肌肉减少型肥胖与慢性肺病和呼气流量峰值的关联:一项基于CHARLS和ELSA的队列研究
IF 2.9 3区 医学
Chronic Respiratory Disease Pub Date : 2026-01-01 Epub Date: 2026-09-11 DOI: 10.1177/14799731261489281
Haodong Guo, Kainan Yao, Changguo Li, Guixing Zhang
{"title":"Associations of sarcopenic obesity with chronic lung disease and peak expiratory flow in middle-aged and older adults: A cohort study based on CHARLS and ELSA.","authors":"Haodong Guo, Kainan Yao, Changguo Li, Guixing Zhang","doi":"10.1177/14799731261489281","DOIUrl":"10.1177/14799731261489281","url":null,"abstract":"<p><p>BackgroundEvidence regarding the associations of sarcopenic obesity (SO) with chronic lung disease (CLD) and peak expiratory flow (PEF) remains limited. This study aimed to investigate the relationships between SO and CLD as well as PEF among middle-aged and older adults in China and the United Kingdom.MethodsData were derived from the China Health and Retirement Longitudinal Study (CHARLS, 2011-2020) and the English Longitudinal Study of Ageing (ELSA, waves 2-6). Cox proportional hazards models were used to evaluate the associations of SO with incident CLD and PEF-related outcomes. Inverse probability of treatment weighting (IPTW) was applied to balance baseline characteristics between participants with and without SO. Random forest-based analyses were conducted as supplementary analyses to support the main findings.ResultsA total of 3,572 participants from CHARLS and 2,436 from ELSA without CLD at baseline were included in the CLD analysis. During follow-up, SO was significantly associated with a higher risk of incident CLD. In the CHARLS cohort, SO was positively associated with CLD risk after full adjustment (Model 3: HR = 1.50, P = 0.003). Consistent results were observed in the ELSA cohort after adjustment for ethnicity (Model 1: HR = 2.19, P = 0.006). Associations between SO and PEF were not consistently observed across cohorts.ConclusionsSarcopenic obesity was associated with an increased risk of chronic lung disease among older adults, suggesting that SO may be a potential body composition-related marker of respiratory risk. Findings related to PEF were exploratory and warrant further investigation.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"23 ","pages":"14799731261489281"},"PeriodicalIF":2.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13570051/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148944520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of social frailty with prognosis among individuals with chronic obstructive pulmonary disease. 慢性阻塞性肺疾病患者社交衰弱与预后的关系
IF 2.9 3区 医学
Chronic Respiratory Disease Pub Date : 2026-01-01 Epub Date: 2026-07-18 DOI: 10.1177/14799731261471096
Lanquan Li, Naxin Zhang
{"title":"Association of social frailty with prognosis among individuals with chronic obstructive pulmonary disease.","authors":"Lanquan Li, Naxin Zhang","doi":"10.1177/14799731261471096","DOIUrl":"10.1177/14799731261471096","url":null,"abstract":"<p><p>ObjectivesThe relationship between physical or cognitive frailty and chronic obstructive pulmonary disease (COPD) has been established. This study aimed to evaluate the association between social frailty and disease severity as well as prognosis in people with COPD.MethodsEligible people with stable COPD were prospectively enrolled. Baseline data were collected via medical records and face-to-face interviews, and social frailty was assessed using the Makizako Index (grouping criteria). During a 1-year follow-up, changes in participants' disease status and prognostic outcomes were recorded. Multivariate logistic regression was applied to analyze the associations.ResultsOf 725 participants, 281 had social frailty and 444 were non-frail. Baseline social frailty was associated with a greater number of previous acute exacerbations (p<0.001); with a higher risk of frequent acute exacerbations during follow-up (p<0.001); and with higher risks of hospitalization >7 days and ICU stay >3 days at the first acute exacerbation during follow-up (p<0.001, p=0.006). It also predicted greater dyspnea, abnormal blood gas, worse pulmonary function, elevated inflammatory markers, triple therapy escalation, and escalated steroids during this acute exacerbation (all p<0.01).ConclusionSocial frailty may, to a certain extent, serve as a potential predictor for assessing the prognosis of people with COPD.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"23 ","pages":"14799731261471096"},"PeriodicalIF":2.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13380685/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148497183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Digital exclusion faced by people living with chronic respiratory disease: Challenges, implications and solutions. 慢性呼吸道疾病患者面临的数字排斥:挑战、影响和解决办法。
IF 2.9 3区 医学
Chronic Respiratory Disease Pub Date : 2026-01-01 Epub Date: 2026-04-03 DOI: 10.1177/14799731261441307
Grant Trewartha, Lotte Janssens, Samantha Harrison
{"title":"Digital exclusion faced by people living with chronic respiratory disease: Challenges, implications and solutions.","authors":"Grant Trewartha, Lotte Janssens, Samantha Harrison","doi":"10.1177/14799731261441307","DOIUrl":"10.1177/14799731261441307","url":null,"abstract":"<p><p>The introduction of digital health technologies (DHTs) to support the diagnosis, assessment, and management of chronic respiratory diseases (CRD) has great potential to democratise access to healthcare, but will suffer if these new technologies cannot be fully utilised by the patients most at need, particularly those from underserved communities. This narrative review addresses the challenges and potential solutions for reducing digital exclusion for people living with CRD. Although sparse, the available evidence suggests that digital exclusion leads to poorer health outcomes in people living with CRD. The barriers that lead to digital exclusion intersect at many different levels and include socioeconomic, demographic, geographical, digital literacy, design/accessibility and psychosocial factors. Solutions to mitigate digital exclusion in people with CRD need to operate at multiple scales with cross-sectoral collaboration, and range from ensuring access to digital tools via large national mobile/broadband infrastructure developments to ensuring DHTs for patient use are designed inclusively and frontline healthcare staff are trained to help patients engage with the tools. Currently, there is a real risk that deploying digital health interventions for CRD care may widen the digital divide and deepen health inequities. To deliver on the digital health promise, all relevant stakeholders need to be focussed on ensuring that the presence of digital exclusion is well monitored and underserved communities such as CRDs are not systematically excluded from implementation and evaluation efforts.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"23 ","pages":"14799731261441307"},"PeriodicalIF":2.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13051112/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147608387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modernisation of chronic respiratory disease management: The integration of wearable technology. 慢性呼吸系统疾病管理的现代化:可穿戴技术的整合。
IF 2.9 3区 医学
Chronic Respiratory Disease Pub Date : 2026-01-01 Epub Date: 2026-05-20 DOI: 10.1177/14799731261454686
Matthew Armstrong
{"title":"Modernisation of chronic respiratory disease management: The integration of wearable technology.","authors":"Matthew Armstrong","doi":"10.1177/14799731261454686","DOIUrl":"10.1177/14799731261454686","url":null,"abstract":"<p><p>Chronic respiratory diseases such as Chronic Obstructive Pulmonary Disease, Asthma, Interstitial Lung Disease, Cystic Fibrosis, and Pulmonary Hypertension affect over 500 million people globally and pose significant challenges for diagnosis, management, and long-term care. Traditional approaches often rely on episodic clinical assessments and patient-reported symptoms, which fail to capture the dynamic nature of respiratory health. The integration of wearable technology offers a transformative solution, enabling continuous, real-time monitoring of physiological and behavioural parameters. This review explores the evolving role of wearable devices, including activity trackers, smartwatches, spirometers, and biosensors, in modernising chronic respiratory disease management. Evidence across disease domains demonstrates that wearables can enhance physical activity, predict exacerbations, support remote rehabilitation, and facilitate personalised care. In Chronic obstructive pulmonary disease, step counters and biometric sensors have shown improvements in activity levels and early exacerbation detection. Asthma care benefits from AI-driven platforms that integrate environmental and physiological data to optimise treatment. For Interstitial lung disease and Cystic fibrosis, home spirometry and sweat biomarker monitoring empower patients and improve disease tracking. In Pulmonary hypertension, wearables provide insights into activity and sleep patterns, complementing traditional assessments. Despite promising outcomes, barriers remain. Technical limitations, data reliability, digital literacy, privacy concerns, and integration into clinical workflows hinder widespread adoption. Economic and equity considerations further challenge scalability, particularly in low-resource settings. Looking forward, the convergence of multimodal sensing, AI analytics, and digital therapeutics will enable proactive, personalised, and equitable respiratory care. Addressing validation, interoperability, and ethical governance will be critical to realising the full potential of wearable technology in CRD management.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"23 ","pages":"14799731261454686"},"PeriodicalIF":2.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13191128/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147971050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Methodological considerations regarding the interpretation of feasibility outcomes in remote breathing interventions for dysregulated breathing following COVID-19. 关于COVID-19后呼吸失调远程呼吸干预可行性结果解释的方法学考虑。
IF 2.9 3区 医学
Chronic Respiratory Disease Pub Date : 2026-01-01 Epub Date: 2026-08-23 DOI: 10.1177/14799731261483640
Raju Kumar, Palakdeep Kaur, Nitin Kumar Indora
{"title":"Methodological considerations regarding the interpretation of feasibility outcomes in remote breathing interventions for dysregulated breathing following COVID-19.","authors":"Raju Kumar, Palakdeep Kaur, Nitin Kumar Indora","doi":"10.1177/14799731261483640","DOIUrl":"10.1177/14799731261483640","url":null,"abstract":"","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"23 ","pages":"14799731261483640"},"PeriodicalIF":2.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13500948/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148788834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exercise intensity during a minimal equipment circuit session in adults with chronic respiratory disease. 成人慢性呼吸系统疾病患者在最小设备循环期间的运动强度。
IF 2.9 3区 医学
Chronic Respiratory Disease Pub Date : 2026-01-01 Epub Date: 2026-09-04 DOI: 10.1177/14799731261486039
Christie R Mellerick, Angela T Burge, Narelle S Cox, Anthony May, Janet Bondarenko, Melissa Chong, Anne E Holland
{"title":"Exercise intensity during a minimal equipment circuit session in adults with chronic respiratory disease.","authors":"Christie R Mellerick, Angela T Burge, Narelle S Cox, Anthony May, Janet Bondarenko, Melissa Chong, Anne E Holland","doi":"10.1177/14799731261486039","DOIUrl":"10.1177/14799731261486039","url":null,"abstract":"<p><p>ObjectivePulmonary rehabilitation is recommended for people with chronic respiratory disease, yet attendance barriers persist. There is increasing interest in models that may overcome some of these barriers, including minimal equipment exercise training. The capacity of a purely minimal equipment circuit to elicit an acute physiological response sufficient to confer health benefits has not been evaluated. This study assessed whether a minimal equipment circuit session enabled participants to achieve a training intensity of ≥60% <math><mrow><mover><mi>V</mi><mo>˙</mo></mover></mrow></math>O<sub>2</sub>peak.MethodsPeople with chronic respiratory disease referred to pulmonary rehabilitation completed a cardiopulmonary exercise test to determine peak oxygen consumption (<math><mrow><mover><mi>V</mi><mo>˙</mo></mover></mrow></math>O<sub>2</sub>peak), followed by a 60-minute minimal equipment exercise circuit training session. The session included 3 circuits each comprising 7 exercise stations including upper- and lower-limb training. Physiological signs and symptoms were monitored throughout. The primary outcome was the percentage of session spent at or above the desired training intensity (≥60% <math><mrow><mover><mi>V</mi><mo>˙</mo></mover></mrow></math>O<sub>2</sub>peak).ResultsEighteen participants completed the study (mean (SD) age 67 (11) years). Participants spent a mean 72% (21) of the session at ≥60% <math><mover><mi>V</mi><mo>˙</mo></mover></math>O<sub>2</sub>peak, with a median [IQR] of 40[32-47] minutes above this threshold. Fifteen participants (83%) achieved the target intensity for ≥30 minutes. Participants reported positive immediate ratings of confidence, comfort, and enjoyment (5-point Likert scale median 5, IQR 4-5) at the conclusion of the minimal equipment session.ConclusionA minimal equipment exercise training session can provide an exercise intensity of ≥60% <math><mrow><mover><mi>V</mi><mo>˙</mo></mover></mrow></math>O<sub>2</sub>peak for >70% of the exercise session in people with chronic respiratory disease. This approach requires further investigation as to whether it may support pulmonary rehabilitation delivery in diverse settings.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"23 ","pages":"14799731261486039"},"PeriodicalIF":2.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13547803/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Post COVID REspiratory mechanisms and the efficacy of a breathing exercise intervention for DYsregulated breathing (Remedy): A feasibility RCT study. COVID后呼吸机制和呼吸运动干预呼吸失调(补救)的疗效:一项可行性RCT研究。
IF 2.9 3区 医学
Chronic Respiratory Disease Pub Date : 2026-01-01 Epub Date: 2026-06-16 DOI: 10.1177/14799731261454679
Harvey-Dunstan Tc, Chikuri S, Kaur J, Porte J, Middleton S, Moffatt F, McKeever Tm, Bolton Ce
{"title":"Post COVID REspiratory mechanisms and the efficacy of a breathing exercise intervention for DYsregulated breathing (Remedy): A feasibility RCT study.","authors":"Harvey-Dunstan Tc, Chikuri S, Kaur J, Porte J, Middleton S, Moffatt F, McKeever Tm, Bolton Ce","doi":"10.1177/14799731261454679","DOIUrl":"10.1177/14799731261454679","url":null,"abstract":"<p><p>BackgroundDysregulated breathing is a major cause of persisting breathlessness for many people following acute COVID-19 illness. There is little evidence to support the use of breathing interventions within this population.MethodsA feasibility study was conducted to investigate the potential role of supervised, remote online yogic breathing as an intervention, compared to usual care. The intervention was a six-week group programme, in which they were encouraged to attend bi-weekly. Primary outcomes of attendance, completion and acceptability were recorded and a survey following the intervention. Secondary measures of breathlessness and physical function were collected.ResultsOf 122 people invited who had reported dysregulated breathing at the time of clinical consult, 40 consented and 34 were randomised (Intervention n=17, usual care n=17), 33 had initial assessment (n=16 and n=17) and with post-intervention outcomes available in n=13 and n=14, respectively. Of the 13 in the intervention arm, 5 people completed >75% of sessions and the post intervention assessment. The median number of sessions attended per participant was 7. No safety issues were recorded. The survey (n=13) of the actual intervention highlighted it was well received but there was limited options for attending. Although some breathlessness measures improved in the people receiving the intervention, there was no significant difference when comparing the intervention to usual care arms.ConclusionsThe feasibility of the study was limited in this select population of people after COVID-19 with dysregulated breathing. The intervention was well received, but attendance at all the sessions was challenged by the limited options for the sessions.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"23 ","pages":"14799731261454679"},"PeriodicalIF":2.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13272870/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148257475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and impact of insomnia in patients with chronic obstructive pulmonary disease. 慢性阻塞性肺疾病患者失眠的患病率及影响
IF 2.9 3区 医学
Chronic Respiratory Disease Pub Date : 2026-01-01 Epub Date: 2026-09-18 DOI: 10.1177/14799731261490558
Aureliano Ais-Daza, Angel Carmona-Gonzalez, Sofía Gutierrez-Hernandez, Isabel Castillo-Rivillas, Aurelio Arnedillo-Lopez, Aurelio Arnedillo-Muñoz
{"title":"Prevalence and impact of insomnia in patients with chronic obstructive pulmonary disease.","authors":"Aureliano Ais-Daza, Angel Carmona-Gonzalez, Sofía Gutierrez-Hernandez, Isabel Castillo-Rivillas, Aurelio Arnedillo-Lopez, Aurelio Arnedillo-Muñoz","doi":"10.1177/14799731261490558","DOIUrl":"10.1177/14799731261490558","url":null,"abstract":"<p><p>ObjectivesTo determine the prevalence of insomnia in patients with chronic obstructive pulmonary disease (COPD) and evaluate its association with health status, pulmonary function, anxiety/depression, and exacerbations.MethodsA cross-sectional observational study was conducted including consecutive COPD outpatients. Data collected included sociodemographic and clinical variables, daytime sleepiness (Epworth Sleepiness Scale), quality of life (COPD Assessment Test, CAT), anxiety and depression (HADS), insomnia severity (Insomnia Severity Index, ISI), and exacerbations in the previous year. Multivariable logistic regression analysis was performed to identify independent predictors of insomnia.ResultsA total of 103 patients (77 males, 26 females) were included. Insomnia prevalence was 38.8% (32.5% mild, 55.0% moderate, 12.5% severe). No significant differences in pulmonary function were observed between patients with and without insomnia. However, patients with insomnia had poorer health status (CAT 19.13±8.63 vs. 11.32±8.13; p<0.001), greater daytime sleepiness (Epworth 5.23±3.10 vs. 3.84±2.31; p<0.011), higher anxiety prevalence (61.5% vs. 31.2%; OR=3.533), and more exacerbations (50% vs. 28.6%; OR=2.5; p<0.037). In multivariable analysis, the CAT score was the only independent predictor of insomnia (OR 1.083; 95% CI 1.011-1.160; <i>p</i> = 0.023).ConclusionsInsomnia is highly prevalent in COPD and is associated with poorer health status, greater daytime sleepiness, increased anxiety, and more frequent exacerbations. Poorer health status was the only independent predictor of insomnia.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"23 ","pages":"14799731261490558"},"PeriodicalIF":2.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148988166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Forced oscillometry technique in the assessment of adults with cystic fibrosis treated for a pulmonary exacerbation, a pilot feasibility study. 强迫振荡测量技术在成人囊性纤维化肺恶化治疗中的评估,一个试点可行性研究。
IF 2.3 3区 医学
Chronic Respiratory Disease Pub Date : 2026-01-01 Epub Date: 2026-01-04 DOI: 10.1177/14799731251414105
James Nolan, Jennifer Bingham, Robyn Cobb, Kathleen Hall, Pei Onn, Karen Hay, Michelle Wood, David W Reid
{"title":"Forced oscillometry technique in the assessment of adults with cystic fibrosis treated for a pulmonary exacerbation, a pilot feasibility study.","authors":"James Nolan, Jennifer Bingham, Robyn Cobb, Kathleen Hall, Pei Onn, Karen Hay, Michelle Wood, David W Reid","doi":"10.1177/14799731251414105","DOIUrl":"10.1177/14799731251414105","url":null,"abstract":"<p><p>IntroductionEffective management of pulmonary exacerbations (PEx) in cystic fibrosis (CF) is essential to minimise lung damage and reduce morbidity and mortality. Spirometry, the standard tool for lung function assessment in adult people with CF (pwCF), has limitations. Forced Oscillometry Technique (FOT) is an effort-independent method that assesses small airways disease and has been validated in other respiratory conditions. This study evaluated the feasibility and acceptability of implementing FOT during treatment for PEx in adult pwCF.MethodsTwelve adult pwCF underwent FOT and spirometry at the start and end of PEx treatment, and at clinically convenient intervals. FOT was also measured before and after physiotherapy-directed airway clearance. A questionnaire assessed patient satisfaction with FOT.ResultsAll patients had spirometry below baseline at PEx onset and small airways dysfunction on FOT. Treatment was associated with improvements in median FEV1pp (5.1%, <i>p</i> = 0.050) and X5 (0.2 cm H<sub>2</sub>O/L/s, <i>p</i> = 0.023), with a significant association between FEV1pp and X5 (<i>p</i> = 0.004). There was no significant FOT change after airway clearance. Patients rated FOT more favourably than spirometry.DiscussionFOT is feasible, well-tolerated, and may complement spirometry in assessing adult pwCF during PEx. Further studies are warranted.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"23 ","pages":"14799731251414105"},"PeriodicalIF":2.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12775344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145899158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implementation of the treatable traits approach in a regional clinic: Improving health outcomes in adults with bronchiectasis. 可治疗特征方法在地区诊所的实施:改善成人支气管扩张的健康结果。
IF 2.9 3区 医学
Chronic Respiratory Disease Pub Date : 2026-01-01 Epub Date: 2026-01-29 DOI: 10.1177/14799731251408842
Kirsty E Krieg, Annemarie L Lee, Tiffany J Dwyer, Zoe J McKeough
{"title":"Implementation of the treatable traits approach in a regional clinic: Improving health outcomes in adults with bronchiectasis.","authors":"Kirsty E Krieg, Annemarie L Lee, Tiffany J Dwyer, Zoe J McKeough","doi":"10.1177/14799731251408842","DOIUrl":"10.1177/14799731251408842","url":null,"abstract":"<p><p>ObjectivesTreatable traits are identifiable and treatable features of disease. The primary objective was to evaluate whether a bronchiectasis clinic in a regional setting, implementing a treatable traits approach, would lead to improvements in quality of life. Secondary objectives were to evaluate clinic implementation outcomes, annual exacerbations and hospitalisation.MethodsAn implementation study. Adults with bronchiectasis attending an outpatient clinic in Rockhampton, Australia between 2021 and 2023 were recruited. Clinical care was implemented by a physiotherapist and nurses according to traits identified. Quality of life (QoL-Bronchiectasis respiratory symptom score (QoL-B rs), Leicester Cough Questionnaire (LCQ) total score) was evaluated at baseline, three and 12-months from first attendance. Implementation outcomes were determined by clinic appointment uptake and attendance and pulmonary rehabilitation uptake and completion at 12-months. Exacerbation frequency and hospitalisation for the 12-months before and after enrolment were compared.Results50 participants were recruited [mean (SD) age 71 (12) years; Bronchiectasis Severity Index (%) mild (22) moderate (44) severe (34)]. There was a significant improvement in QoL at three and 12-months from baseline (mean difference, 95% CI) [3 months: QoL-B rs 9.2 (3.2-15.2), LCQ 1.7 (0.6-2.8); 12-months: QoL-B rs 10.1 (3.9-16.3), LCQ 1.8 (0.8-2.8)]. Clinic uptake (91%), attendance (97%) and pulmonary rehabilitation uptake (74%) and completion (84%) were high. Exacerbation frequency [median (IQR) 1.0 (3.0) to 0.0 (1.0), p = 0.007], and hospitalisation decreased (18% vs 0%, p = 0.005).DiscussionA treatable traits approach improved quality of life, was feasible, including the achievement of high pulmonary rehabilitation uptake and completion, and reduced exacerbation frequency and hospitalisation.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"23 ","pages":"14799731251408842"},"PeriodicalIF":2.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12858780/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146084478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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