Chronic Respiratory Disease最新文献

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The impact on thirty day readmissions for patients hospitalized for acute exacerbations of chronic obstructive pulmonary disease admitted to an observation unit versus an inpatient medical unit: A retrospective observational study. 因慢性阻塞性肺病急性加重而住院的患者在观察室与住院医疗室住院三十天再入院的影响:回顾性观察研究。
IF 4.1 3区 医学
Chronic Respiratory Disease Pub Date : 2024-01-01 DOI: 10.1177/14799731241242490
Jacob Bell, Steven Lim, Takahisa Mikami, Jeeyune Bahk, Stephen Argiro, David Steiger
{"title":"The impact on thirty day readmissions for patients hospitalized for acute exacerbations of chronic obstructive pulmonary disease admitted to an observation unit versus an inpatient medical unit: A retrospective observational study.","authors":"Jacob Bell, Steven Lim, Takahisa Mikami, Jeeyune Bahk, Stephen Argiro, David Steiger","doi":"10.1177/14799731241242490","DOIUrl":"10.1177/14799731241242490","url":null,"abstract":"<p><strong>Objectives: </strong>We aimed to evaluate the utility of an Observation Unit (OU) in management of acute exacerbations of chronic obstructive pulmonary disease (AECOPD) and to identify the clinical characteristics of patients readmitted within 30-days for AECOPD following index admission to the OU or inpatient floor from the OU.</p><p><strong>Methods: </strong>This is a retrospective observational study of patients admitted from January to December 2017 for AECOPD to an OU in an urban-based tertiary care hospital. Primary outcome was rate of 30-day readmission after admission for AECOPD for patients discharged from the OU versus inpatient service after failing OU management. Regression analyses were used to define risk factors.</p><p><strong>Results: </strong>163 OU encounters from 92 unique patients were included. There was a lower readmission rate (33%) for patients converted from OU to inpatient care versus patients readmitted after direct discharge from the OU (44%). Patients with 30-day readmissions were more likely to be undomiciled, with history of congestive heart failure (CHF), pulmonary embolism (PE), or had previous admissions for AECOPD. Patients with >6 annual OU visits for AECOPD had higher rates of substance abuse, psychiatric diagnosis, and prior PE; when these patients were excluded, the 30-day readmission rate decreased to 13.5%.</p><p><strong>Conclusion: </strong>Patients admitted for AECOPD with a history of PE, CHF, prior AECOPD admissions, and socioeconomic deprivation are at higher risk of readmission and should be prioritized for direct inpatient admission. Further prospective studies should be conducted to determine the clinical impact of this approach on readmission rates.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10981268/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140305102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Respiratory impairments in patients suffering from Fabry disease - A cross-sectional study. 法布里病患者的呼吸障碍--一项横断面研究。
IF 4.1 3区 医学
Chronic Respiratory Disease Pub Date : 2024-01-01 DOI: 10.1177/14799731231221821
Huma Ahmed, Vibeke Backer, Grigoris Effraimidis, Åse Krogh Rasmussen, Caroline Michaela Kistorp, Ulla Feldt-Rasmussen
{"title":"Respiratory impairments in patients suffering from Fabry disease - A cross-sectional study.","authors":"Huma Ahmed, Vibeke Backer, Grigoris Effraimidis, Åse Krogh Rasmussen, Caroline Michaela Kistorp, Ulla Feldt-Rasmussen","doi":"10.1177/14799731231221821","DOIUrl":"10.1177/14799731231221821","url":null,"abstract":"<p><strong>Background: </strong>The inherited X-linked disorder, Fabry disease, is caused by deficient lysosomal enzyme α-galactosidase A, with progressive accumulation of globotriaosylceramide in multiple organs including the upper and lower airways.</p><p><strong>Objectives: </strong>To assess pulmonary function at the time of the first pulmonary function test (PFT) performed among the National Danish Fabry cohort and define the prevalence of affected lung function variables.</p><p><strong>Materials and method: </strong>A cross-sectional retrospective cohort study of 86 adult patients enrolled in one or both international patient registry databases for Fabry disease, <i>Fabry Registry</i> or <i>FollowME</i> with at least one PFT. The Mainz Severity Score Index (MSSI) was calculated to determine the disease severity. Lung function variables were examined by multivariate regression adjusted for important variables for developing airway illness.</p><p><strong>Results: </strong>Seventeen patients (20%) showed obstructive airflow limitation and 7 (8%) a restrictive lung deficiency. Smoking status (<i>p</i> = .016) and MSSI (<i>p</i> < .001) were associated with increasing obstructive airway limitation.</p><p><strong>Conclusion: </strong>The prevalence of affected lung function among the National Danish Fabry cohort was 28%. Patients with classic gene variants frequently developed a decrease in lung function regardless of their smoking status, with significant relationship with disease severity.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10858660/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139706271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors influencing patient-provider communication about subjective cognitive decline in people with COPD: Insights from a national survey. 影响慢性阻塞性肺病患者与医护人员就主观认知能力下降进行沟通的因素:一项全国性调查的启示。
IF 3.5 3区 医学
Chronic Respiratory Disease Pub Date : 2024-01-01 DOI: 10.1177/14799731241268338
Michael Stellefson, Min Qi Wang, Olivia Campbell
{"title":"Factors influencing patient-provider communication about subjective cognitive decline in people with COPD: Insights from a national survey.","authors":"Michael Stellefson, Min Qi Wang, Olivia Campbell","doi":"10.1177/14799731241268338","DOIUrl":"10.1177/14799731241268338","url":null,"abstract":"<p><p><b>Objective:</b> While there is a growing body of evidence indicating a relationship between COPD and cognitive impairment, there is a gap in evidence regarding discussions of cognitive symptoms in healthcare settings. This study investigated the extent to which individuals with Chronic Obstructive Pulmonary Disease (COPD) and Subjective Cognitive Decline (SCD) self-reported confusion or memory loss with healthcare professionals. <b>Methods:</b> A secondary analysis of 2019 BRFSS data of US adults aged 45+ with COPD (<i>N</i> = 107,204), using logistic regression to explore associations between socio-demographic and health-related indicators with discussion of cognitive symptoms with healthcare professionals. <b>Results:</b> Less than half (45.88%) of individuals reporting SCD discussed their cognitive symptoms with their healthcare provider. In the adjusted model, unemployed (AOR = 2.92, 95% CI: 1.70-5.02, <i>p</i> < .005), retired (AOR = 3.16, 95% CI: 1.37-7.30, <i>p</i> < .01), and current smokers (AOR = 1.73, 95% CI: 1.02-2.93, <i>p</i> < .05) were more likely to discuss cognitive decline with a healthcare professional than their counterparts. In contrast, males (AOR = 0.53, 95% CI: 0.32-0.86, <i>p</i> < .05) and binge drinkers (AOR = 0.49, 95% CI: 0.30-0.79, <i>p</i> < .01) were significantly less likely to do so when compared to their counterparts. <b>Discussion:</b> The study highlighted significant disparities in the likelihood of individuals with COPD discussing cognitive symptoms based on socio-demographic and health risk behaviors. <b>Conclusion:</b> Addressing gender disparities, occupational status, and personal health risks is crucial for improving patient-provider communication about SCD among adults with COPD.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11292718/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141859200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Two-year diffusion capacity trajectory in COVID-19 pneumonia survivors. COVID-19 肺炎幸存者两年的扩散能力轨迹。
IF 4.1 3区 医学
Chronic Respiratory Disease Pub Date : 2024-01-01 DOI: 10.1177/14799731231222284
Marlise P de Roos, Rick M Heijnen, Nynke G Dijkstra, Kees Brinkman, Nini H Jonkman, Paul Bresser
{"title":"Two-year diffusion capacity trajectory in COVID-19 pneumonia survivors.","authors":"Marlise P de Roos, Rick M Heijnen, Nynke G Dijkstra, Kees Brinkman, Nini H Jonkman, Paul Bresser","doi":"10.1177/14799731231222284","DOIUrl":"10.1177/14799731231222284","url":null,"abstract":"<p><p>Reduced diffusion capacity (DLCO) after COVID 19 pneumonia was reported in hospitalised patients after discharge. Here, we studied the restoration of DLCO over a 24 months period in COVID-19 pneumonia survivors (<i>n</i> = 317), who were categorised into \"moderate\" cases (no oxygen supply; no need for hospitalisation), \"severe\" cases (respiratory frequency > 30/min and/or peripheral oxygen SpO2 < 93%), and \"critical\" cases (respiratory failure and admission into the intensive care unit). COVID-19 pneumonia survivors with a decreased DLCO (<80%) at 3 months (<i>n</i> = 133) were invited for 6- and 24-months follow-up. At 3 months, impairment of DLCO was more severe in critical case (<i>p</i> < .01). Over time, the subgroups showed a similar level of improvement; and, there was no difference in recovery over time between the subgroups. At 24 months, the DLCO did not differ between the subgroups, with a mean DLCO of 73% for all patients. At 24 months, 65% of patients still had a DLCO < 80%, and in 40% of patients DLCO was <70% of predicted. Regardless the initial disease severity, all COVID-19 survivors showed improvement in DLCO during follow-up; however, DLCO had not normalised in the majority of patients with a DLCO <80% 3 months after hospital discharge.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10858671/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139706272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Validity and reliability of the Dutch version of the S3-NIV questionnaire to evaluate long-term noninvasive ventilation. 用于评估长期无创通气的荷兰语版 S3-NIV 问卷的有效性和可靠性。
IF 4.1 3区 医学
Chronic Respiratory Disease Pub Date : 2024-01-01 DOI: 10.1177/14799731241236741
Charlotte Gw Seijger, Bettine Ah Vosse, Leandre la Fontaine, Tim Raveling, Nicolle Am Cobben, Peter J Wijkstra
{"title":"Validity and reliability of the Dutch version of the S3-NIV questionnaire to evaluate long-term noninvasive ventilation.","authors":"Charlotte Gw Seijger, Bettine Ah Vosse, Leandre la Fontaine, Tim Raveling, Nicolle Am Cobben, Peter J Wijkstra","doi":"10.1177/14799731241236741","DOIUrl":"10.1177/14799731241236741","url":null,"abstract":"<p><strong>Objectives: </strong>Noninvasive ventilation (NIV) is an effective treatment for chronic respiratory failure (CRF). Patient-centered outcomes need to be evaluated regularly and the S<sup>3</sup>-NIV questionnaire seems an applicable tool. We translated this short, self-administered questionnaire into a Dutch version and tested its construct validity and reliability.</p><p><strong>Methods: </strong>An observational study was conducted, including 127 stable long-term NIV users with CRF or complex sleep related breathing disorders due to different underlying diseases: chronic obstructive pulmonary disease (25%), slowly progressive neuromuscular disorders (35%), rapidly progressive neuromuscular disorders (12%) and 'other disorders' (28%) including complex sleep apnea and obesity hypoventilation syndrome. Construct validity and reliability were tested.</p><p><strong>Results: </strong>The Dutch version of the questionnaire was obtained after a translation and back-translation process. Internal consistency of the total score was good (Cronbach's α coefficient of 0.78) as well as for the 'respiratory symptoms' subdomain and the 'sleep and side effects' subdomain (Cronbach's α coefficient of 0.78 and 0.69, respectively). The reproducibility was excellent with an intraclass correlation of 0.89 (95% CI 0.87-0.93). Construct validity was good for the 'respiratory symptoms' subdomain.</p><p><strong>Conclusion: </strong>The Dutch S<sup>3</sup>-NIV questionnaire is a reliable and valid tool to evaluate symptoms, sleep, and NIV related side effects in long-term NIV users.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10906045/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139989484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantifying uptake and completion of pulmonary rehabilitation programs in people with chronic obstructive pulmonary disease known to tertiary care. 量化三级医疗机构已知的慢性阻塞性肺病患者接受和完成肺康复计划的情况。
IF 4.1 3区 医学
Chronic Respiratory Disease Pub Date : 2024-01-01 DOI: 10.1177/14799731231224781
Sarah Hug, Vinicius Cavalheri, Daniel F Gucciardi, Kylie Hill
{"title":"Quantifying uptake and completion of pulmonary rehabilitation programs in people with chronic obstructive pulmonary disease known to tertiary care.","authors":"Sarah Hug, Vinicius Cavalheri, Daniel F Gucciardi, Kylie Hill","doi":"10.1177/14799731231224781","DOIUrl":"10.1177/14799731231224781","url":null,"abstract":"<p><strong>Background: </strong>People with symptomatic chronic obstructive pulmonary disease (COPD) benefit from pulmonary rehabilitation programs (PRPs), but program attrition is common.</p><p><strong>Methods: </strong>For people with COPD who presented to tertiary care and appeared appropriate for a PRP, we prospectively mapped their PRP journey, explored factors influencing attendance to pre-program assessment and captured program attrition.</p><p><strong>Results: </strong>Of the 391 participants, 31% (95% CI 27 to 36) were referred to a PRP (<i>n</i> = 123; age 68 ± 10years, 62 males [50%], FEV<sub>1</sub> 45 ± 19%predicted). Of those referred, 94 (76% [69 to 84]) attended a pre-program assessment. Ex-smokers and those who had a healthcare professional (HCP) explain they would be referred were more likely to attend a pre-program assessment (odds ratio [95%CI]; 2.6 [1.1 to 6.1]; and 4.7 [1.9 to 11.7], respectively). Of the 94 who attended, 63 (67% [58 to 77]) commenced; and of those who commenced, 35 (56% [43 to 68]) completed a PRP. All who completed (<i>n</i> = 35, 100%) were provided at least one strategy to maintain training-related gains.</p><p><strong>Conclusion: </strong>Attrition occurs throughout the PRP journey. Interactions with HCPs about PRPs positively influenced attendance. Understanding how HCPs can best contextualise PRPs to encourage referral acceptance and uptake is an important area for further work.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10771047/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139105898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Asthma and obstructive sleep apnea: Unveiling correlations and treatable traits for comprehensive care. 哮喘与阻塞性睡眠呼吸暂停:揭示相关性和可治疗特征,实现全面护理。
IF 3.5 3区 医学
Chronic Respiratory Disease Pub Date : 2024-01-01 DOI: 10.1177/14799731241251827
Verónica Pardo-Manrique, Ciro D Ibarra-Enríquez, Carlos D Serrano, Fernando Sanabria, Liliana Fernandez-Trujillo
{"title":"Asthma and obstructive sleep apnea: Unveiling correlations and treatable traits for comprehensive care.","authors":"Verónica Pardo-Manrique, Ciro D Ibarra-Enríquez, Carlos D Serrano, Fernando Sanabria, Liliana Fernandez-Trujillo","doi":"10.1177/14799731241251827","DOIUrl":"10.1177/14799731241251827","url":null,"abstract":"<p><p>Asthma and obstructive sleep apnea (OSA) are common respiratory disorders. They share characteristics such as airway obstruction, poor sleep quality, and low quality of life. They are often present as comorbidities, along with obesity, gastroesophageal reflux disease (GERD), and allergic rhinitis (AR), which impacts the disease's control. In recent years, there has been discussion about the association between these conditions and their pathophysiological and clinical consequences, resulting in worse health outcomes, increased healthcare resource consumption, prolonged hospital stays, and increased morbidity and mortality. Some studies demonstrate that treatment with continuous positive airway pressure (CPAP) can have a beneficial effect on both pathologies. This review summarizes the existing evidence of the association between asthma and OSA at their pathophysiological, epidemiological, clinical, and therapeutic levels. It intends to raise awareness among healthcare professionals about these conditions and the need for further research.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11080759/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140876019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relevance of multidimensional dyspnea assessment in the context of pulmonary rehabilitation. 多维呼吸困难评估与肺康复的相关性。
IF 3.5 3区 医学
Chronic Respiratory Disease Pub Date : 2024-01-01 DOI: 10.1177/14799731241255135
Virginie Molinier, Espérance Moine, Pauline Caille, Nathalie Fernandes, François Alexandre, Nelly Heraud
{"title":"Relevance of multidimensional dyspnea assessment in the context of pulmonary rehabilitation.","authors":"Virginie Molinier, Espérance Moine, Pauline Caille, Nathalie Fernandes, François Alexandre, Nelly Heraud","doi":"10.1177/14799731241255135","DOIUrl":"10.1177/14799731241255135","url":null,"abstract":"<p><p><b>Objectives:</b> While dyspnea is the main symptom in chronic obstructive pulmonary disease (COPD), it is often inadequately evaluated in pulmonary rehabilitation (PR), as it is typically measured using only the impact dimension (ID). However, dyspnea is a multidimensional construct including perception (PD) and emotional (ED) domains. Our work aimed to study the complementarity of dyspnea dimensions and their respective ability to identify different evolutions during PR. <b>Methods:</b> 145 people with COPD attending PR were included in this retrospective study. Dyspnea scores from the modified Medical Research Council scale (ID) and the Multidimensional Dyspnea Profile questionnaire (PD/ED), exercise capacity, quality of life at the start (T1) and the end of PR (T2) were collected from existing databases/medical files. The evolution of each dyspnea dimension was evaluated using the delta score between T2-T1. PR response was defined using the minimal clinically important difference. <b>Results:</b> Our results show that each dyspnea dimension was associated with different health-outcomes. Positive correlations were found between PD-ED at baseline and between their T2-T1 delta score (ρ = 0.51; ρ = 0.41 respectively, <i>p</i> < .01), but there was no significant correlation between ID-PD or -ED (<i>p</i> > .05). 51% of the patients did not respond on ID, but 85% of them nonetheless responded on either PD or ED. Finally, 92% of patients responded on at least one dimension after PR. <b>Discussion:</b> Our study emphasizes the significance of assessing each dimension of dyspnea independently and complementary, as dimensions are associated with different elements and evolve differently under PR effects. This approach is crucial to identifying weak points and allows professionals to focus on program elements that most effectively address the specific dimension causing problems.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11271156/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141751238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinically important changes and adverse events with centre-based or home-based pulmonary rehabilitation in chronic respiratory disease: A systematic review and meta-analysis. 慢性呼吸系统疾病患者在中心或家庭进行肺康复治疗后的临床重要变化和不良事件:系统回顾和荟萃分析。
IF 3.5 3区 医学
Chronic Respiratory Disease Pub Date : 2024-01-01 DOI: 10.1177/14799731241277808
Janet Bondarenko, Simone Dal Corso, Michael P Dillon, Sally Singh, Belinda R Miller, Caroline Kein, Anne E Holland, Arwel W Jones
{"title":"Clinically important changes and adverse events with centre-based or home-based pulmonary rehabilitation in chronic respiratory disease: A systematic review and meta-analysis.","authors":"Janet Bondarenko, Simone Dal Corso, Michael P Dillon, Sally Singh, Belinda R Miller, Caroline Kein, Anne E Holland, Arwel W Jones","doi":"10.1177/14799731241277808","DOIUrl":"10.1177/14799731241277808","url":null,"abstract":"<p><p><b>Objectives:</b> To determine the proportion of people who achieve minimal clinically important differences (MCID) with centre-based or home-based pulmonary rehabilitation and to synthesise data on adverse events.<b>Methods:</b> Cochrane reviews and electronic databases were searched to identify randomised trials comparing centre-based to home-based pulmonary rehabilitation, or either model to usual care, in people with chronic respiratory disease. Primary outcomes were the proportion of participants achieving MCIDs in exercise capacity and disease-specific quality of life. Secondary outcomes were symptoms and adverse events. Cochrane Risk of Bias 1.0 and GRADE were used to assess the risk of bias and certainty of evidence respectively.<b>Results:</b> Forty-nine trials were eligible. Compared to usual care, a higher proportion of pulmonary rehabilitation participants achieved the MCID for exercise capacity (6MWT: 47% vs 20%, <i>p</i> = 0.11), dyspnoea (43% vs 29%, <i>p</i> = 0.0001), fatigue (48% vs 27%, <i>p</i> = 0.0002) and emotional function (37% vs 25%, <i>p</i> = 0.02), with all of these between group differences statistically significant except for exercise capacity. There were no differences between centre-based and home-based pulmonary rehabilitation in the proportion of participants who achieved MCIDs (34%- 58% across studies). Ninety percent of trials reported no adverse events. Certainty of evidence was low-to- moderate with all outcomes except for CRQ-mastery (centre-based vs home-based pulmonary rehabilitation, or pulmonary rehabilitation vs usual care in COPD), ESWT (pulmonary rehabilitation vs usual care in COPD) and 6MWT (pulmonary rehabilitation vs usual care in bronchiectasis) where evidence was very uncertain.<b>Discussion:</b> Clinically meaningful outcomes are achieved by similar proportions of participants in centre-based and home-based pulmonary rehabilitation, with few adverse events. Reporting of trial outcomes according to MCIDs is necessary for informed decision making regarding pulmonary rehabilitation models.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11348370/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142072174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Physical activity coaching in patients with interstitial lung diseases: A randomized controlled trial. 间质性肺病患者的体育锻炼指导:随机对照试验。
IF 4.1 3区 医学
Chronic Respiratory Disease Pub Date : 2024-01-01 DOI: 10.1177/14799731241235231
Sofie Breuls, Tamara Zlamalova, Katerina Raisova, Astrid Blondeel, Marieke Wuyts, Martin Dvoracek, Monika Zurkova, Jonas Yserbyt, Wim Janssens, Wim Wuyts, Thierry Troosters, Heleen Demeyer
{"title":"Physical activity coaching in patients with interstitial lung diseases: A randomized controlled trial.","authors":"Sofie Breuls, Tamara Zlamalova, Katerina Raisova, Astrid Blondeel, Marieke Wuyts, Martin Dvoracek, Monika Zurkova, Jonas Yserbyt, Wim Janssens, Wim Wuyts, Thierry Troosters, Heleen Demeyer","doi":"10.1177/14799731241235231","DOIUrl":"10.1177/14799731241235231","url":null,"abstract":"<p><strong>Objectives: </strong>Physical activity is reduced in patients with interstitial lung disease (ILD) and physical inactivity is related to poor health outcomes. We investigated the effect of a telecoaching intervention to improve physical activity in patients with ILD.</p><p><strong>Methods: </strong>Eighty patients with ILD were randomized into the intervention or control group. Patients in the intervention group received a 12-week telecoaching program including a step counter, a patient-tailored smartphone application, and coaching calls. Patients in the control group received usual care. Physical activity (primary outcome), physical fitness and quality of life were measured at baseline and 12 weeks later with an accelerometer, 6-min walking test and quadriceps muscle force and the King's Brief Interstitial Lung Disease questionnaire (K-BILD).</p><p><strong>Results: </strong>Participation in telecoaching did not improve physical activity: between-group differences for step count: 386 ± 590 steps/day, <i>p</i> = .52; sedentary time: 4 ± 18 min/day, <i>p</i> = .81; movement intensity: 0.04 ± 0.05 m/s<sup>2</sup>, <i>p</i> = .45). Between-group differences for the 6-min walking test, quadriceps muscle force and K-BILD were 14 ± 10 m, <i>p</i> = .16; 2 ± 3% predicted, <i>p</i> = .61; 0.8 ± 1.7 points, <i>p</i> = .62 respectively.</p><p><strong>Conclusions: </strong>Twelve weeks of telecoaching did not improve physical activity, physical fitness or quality of life in patients with ILD. Future physical or behavioural interventions are needed for these patients to improve physical activity.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10956148/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140173963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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