Chronic Respiratory Disease最新文献

{"title":"Development and implementation of the lung volume reduction pulmonary rehabilitation tool to identify eligibility for lung volume reduction in people with chronic obstructive pulmonary disease during pulmonary rehabilitation.","authors":"Sara C Buttery,&nbsp;Parris J Williams,&nbsp;Lisa J Brighton,&nbsp;Craig Batista,&nbsp;Amy Dewar,&nbsp;Lauren Hogg,&nbsp;Karen Ingram,&nbsp;Gemma Korff,&nbsp;Maria Koulopoulou,&nbsp;Helen Lammin,&nbsp;Matthew Maddocks,&nbsp;Lynn McDonnell,&nbsp;Bhavin Mehta,&nbsp;Victoria Meyrick,&nbsp;Lisa Pritchard,&nbsp;Oliver Smith,&nbsp;Puja Trivedi,&nbsp;Rod A Lawson,&nbsp;Nicholas S Hopkinson","doi":"10.1177/14799731231198863","DOIUrl":"10.1177/14799731231198863","url":null,"abstract":"<p><strong>Background: </strong>Completion of pulmonary rehabilitation is recognised in chronic obstructive pulmonary disease (COPD) guidelines as a key opportunity to consider systematically whether a respiratory review to assess potential suitability for a lung volume reduction (LVR) procedure might be appropriate. We describe the development of a simple decision-support tool (the LVR-PR tool) to aid clinicians working in pulmonary rehabilitation, to operationalise this process.</p><p><strong>Methods: </strong>We took an iterative mixed methods approach, which was partnership-based and involved an initial consensus survey, focus groups and an observational study cohort at multiple pulmonary rehabilitation centres.</p><p><strong>Results: </strong>Diagnosis (97%), exercise capacity (84%), breathlessness (78%) and co-morbidities (76%) were acknowledged to be essential items for assessing basic LVR eligibility. Collating prior investigations and assessing patient understanding were considered useful but not essential. Clinician concerns included; streamlining the tool; access to clinical information and investigations; and care needed around introducing LVR therapies to patients in a PR setting. Access to clearer information about LVR procedures, the clinician's role in considering eligibility and how educational resources should be delivered were identified as important themes from patient group discussions. The LVR-PR tool was considered to be feasible and valid for implementation in a variety of PR services across the UK subject to the provision of appropriate health professional training. Clinicians working in specialist LVR centres across the UK who were not otherwise involved in the development process confirmed the tool's validity using the content validity index (CVI).</p><p><strong>Interpretation: </strong>The LVR-PR tool appears to be an acceptable tool that can be feasibly implemented in PR services subject to good quality educational resources for both patients and healthcare professionals.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"20 ","pages":"14799731231198863"},"PeriodicalIF":4.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4e/3f/10.1177_14799731231198863.PMC10475255.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10161448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reflecting on the importance of theory-informed qualitative research in people with chronic respiratory disease and their carers.","authors":"Emma L Giles,&nbsp;Samantha L Harrison","doi":"10.1177/14799731231185128","DOIUrl":"https://doi.org/10.1177/14799731231185128","url":null,"abstract":"Theory can be de fi ned as “ a formal logical explanation of some events that includes predictions of how things relate to one another. ” 1 Theory can be used in research in many ways. It can be used to help craft, develop","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"20 ","pages":"14799731231185128"},"PeriodicalIF":4.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288393/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10087276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physical activity in idiopathic pulmonary fibrosis: Longitudinal change and minimal clinically important difference.","authors":"Kazuya Shingai, Toshiaki Matsuda, Yasuhiro Kondoh, Tomoki Kimura, Kensuke Kataoka, Toshiki Yokoyama, Yasuhiko Yamano, Tomoya Ogawa, Fumiko Watanabe, Jun Hirasawa, W Darlene Reid, Ryo Kozu","doi":"10.1177/14799731231221818","DOIUrl":"10.1177/14799731231221818","url":null,"abstract":"<p><strong>Background and objective: </strong>Reference values of physical activity to interpret longitudinal changes are not available in patients with idiopathic pulmonary fibrosis (IPF). This study aimed to define the minimal clinical important difference (MCID) of longitudinal changes in physical activity in patients with IPF.</p><p><strong>Methods: </strong>Using accelerometry, physical activity (steps per day) was measured and compared at baseline and 6-months follow-up in patients with IPF. We calculated MCID of daily step count using multiple anchor-based and distribution-based methods. Forced vital capacity and 6-minute walk distance were applied as anchors in anchor-based methods. Effect size and standard error of measurement were used to calculate MCID in distribution-based methods.</p><p><strong>Results: </strong>One-hundred and five patients were enrolled in the study (mean age: 68.5 ± 7.5 years). Step count significantly decreased from baseline to 6-months follow-up (-461 ± 2402, <i>p</i> = .031). MCID calculated by anchor-based and distribution-based methods ranged from 570-1358 steps.</p><p><strong>Conclusion: </strong>Daily step count significantly declined over 6-months in patients with IPF. MCID calculated by multiple anchor-based and distribution-based methods was 570 to 1358 steps/day. These findings contribute to interpretation of the longitudinal changes of physical activity that will assist its use as a clinical and research outcome in patients with IPF.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"20 ","pages":"14799731231221818"},"PeriodicalIF":4.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138799460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tidal volume expandability and ventilatory efficiency as predictors of mortality in Taiwanese male patients with chronic obstructive pulmonary disease: A 10-year follow-up study - Is V̇O_2peak or FEV₁% the gold standard?","authors":"Ming-Lung Chuang, Yu-Hsun Wang","doi":"10.1177/14799731231220675","DOIUrl":"https://doi.org/10.1177/14799731231220675","url":null,"abstract":"<p><p>Despite our knowledge of the risk factors for mortality associated with chronic obstructive pulmonary disease (COPD), the mortality rate for this condition continues to increase. This study aimed to investigate the predictive power of physiological variables on all-cause mortality in COPD patients compared to peak oxygen uptake (<math><mrow><mover><mi>V</mi><mo>˙</mo></mover></mrow></math>O_2peak) and forced expired volume in one second (FEV₁). We conducted a retrospective study of 182 COPD patients with complete lung function tests, cardiopulmonary exercise testing (CPET), and survival data. Cox regression analysis was used to estimate the hazard ratios for all-cause mortality. The median follow-up period was 6.8 (IQR 3.9-9.2) years. Out of the 182 patients in our study, sixty-two (34.1%) succumbed to various causes. Of these, 27.4% (<i>n</i> = 17) experienced acute exacerbations, 24.2% (<i>n</i> = 15) had advanced cancer, and 12.9% (<i>n</i> = 8) had cardiovascular disease as the primary cause of death. Another 25.8% (<i>n</i> = 16) passed away due to other underlying conditions, while 6.5% (<i>n</i> = 4) had an unknown cause of death. One patient's demise was attributed to a benign tumor, and another's to a connective tissue disease. The ratio of tidal volume to total lung capacity (V_Tpeak/TLC) and the ratio of minute ventilation and <math><mrow><mover><mi>V</mi><mo>˙</mo></mover></mrow></math>O₂ at nadir (<math><mrow><mover><mi>V</mi><mo>˙</mo></mover></mrow></math>_E/<math><mrow><mover><mi>V</mi><mo>˙</mo></mover></mrow></math>O_2nadir) (AUR 0.83, 95% CI 0.76-0.91) were superior predictors of all-cause mortality compared to <math><mrow><mover><mi>V</mi><mo>˙</mo></mover></mrow></math>O_2peak and FEV₁%. A mortality prediction formula was derived using these variables. This study highlights the potential of V_Tpeak/TLC and <math><mrow><mover><mi>V</mi><mo>˙</mo></mover></mrow></math>_E/<math><mrow><mover><mi>V</mi><mo>˙</mo></mover></mrow></math>O_2nadir as predictive markers for COPD all-cause mortality in COPD. CPET is an effective tool for evaluating COPD mortality; however, the predictive equation requires further validation.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"20 ","pages":"14799731231220675"},"PeriodicalIF":4.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10722945/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138799463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A systematic review of exercise studies for individuals hospitalized with an acute exacerbation of chronic obstructive pulmonary disease: Focus on the principles of exercise training.","authors":"Débora Petry Moecke, Kai Zhu, Jagdeep Gill, Shanjot Brar, Polina Petlitsyna, Ashley Kirkham, Mirha Girt, Joel Chen, Hannah Peters, Holly Denson-Camp, Stephanie Crosbie, Pat G Camp","doi":"10.1177/14799731231215363","DOIUrl":"10.1177/14799731231215363","url":null,"abstract":"<p><strong>Background: </strong>For exercise interventions to be effectively reproduced or applied in a \"real world\" clinical setting, clinical trials must thoroughly document all components of the exercise prescription and ensure that participants adhere to each component. However, previous reviews have not critically examined the quality of exercise prescription of inpatient Pulmonary Rehabilitation (PR) programs.</p><p><strong>Objective: </strong>The objectives of this review were to evaluate the (a) application of the principles of exercise training, (b) reporting of the frequency, intensity, time and type (FITT) components of exercise prescription, and (c) reporting of patient's adherence to the FITT components in intervention studies for patients admitted to hospital for an acute exacerbation of chronic obstructive pulmonary disease (AECOPD).</p><p><strong>Methods: </strong>Relevant scientific databases were searched for randomized controlled trials (RCTs) that compared in-hospital PR with usual care for people hospitalized with AECOPD. Title and abstract followed by full-text screening were conducted independently by two reviewers. Data were extracted and synthesized to evaluate the application of the principles of exercise training and the reporting/adherence of the FITT components.</p><p><strong>Results: </strong>Twenty-seven RCTs were included. Only two applied all principles of exercise training. Specificity was applied by 70%, progression by 48%, overload by 37%, initial values by 89% and diminishing returns and reversibility by 37% of trials. Ten trials adequately reported all FITT components. Frequency and type were the components most reported (85% and 81%, respectively), while intensity was less frequently reported (52%). Only three trials reported on the patient's adherence to all four components.</p><p><strong>Conclusions: </strong>Studies have not adequately reported the exercise prescription in accordance with the principles of exercise training nor reported all the FITT components of the exercise prescription and patient's adherence to them. Therefore, interpretation of the current literature is limited and information for developing exercise prescriptions to individuals hospitalized with an AECOPD is lacking.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"20 ","pages":"14799731231215363"},"PeriodicalIF":4.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655651/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134648612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Symptoms burden and rehabilitation preference after an episode of COVID-19: A patients survey.","authors":"Munyra Alhotye,&nbsp;Enya Daynes,&nbsp;Charlotte Gerlis,&nbsp;Sally J Singh","doi":"10.1177/14799731231177316","DOIUrl":"https://doi.org/10.1177/14799731231177316","url":null,"abstract":"<p><strong>Background: </strong>After COVID-19 infection, individuals can experience a variety of symptoms that might require further treatment. Early data showed the value of adapted pulmonary rehabilitation programmes and technology-based interventions. To develop appropriate services, it is important to understand the symptom burden and the preferred mode of rehabilitation delivery.</p><p><strong>Methods: </strong>Post-hospital discharge (H) and post-community-managed (C) individuals received a follow-up call. A survey was completed to assess the most burdensome symptoms for which the patients would require support and their preference for the mode of rehabilitation delivery.</p><p><strong>Results: </strong>Overall, 160 individuals who received a follow-up call completed the survey (51.2% male, mean [SD] age 54 [15] years) and 126 (78.8%) were post-hospital, while 34 (21.3%) had community-managed infections. A total of 101 (63.1%) reported that COVID-19-related symptoms were affecting their daily activities, and 106 (66.3%) reported their desire to be more active. The most common symptoms identified as needing support were fatigue and shortness of breath. Both groups expressed a preference for a face-to-face group programme (C: 54.8%; H: 46.8%), while (38.7%) of post-community-managed individuals and (40.3%) post-hospital patients preferred a supported digital rehabilitation programme. Few opted a non-digital home-based programme (C: 3.2%; H:12.9%, respectively).</p><p><strong>Conclusion: </strong>The survey responses indicated a significant symptom burden that may benefit from an intervention such as rehabilitation. Preferences for rehabilitation indicated that a face-to-face intervention was preferred by the majority, with a large proportion preferring digital intervention.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"20 ","pages":"14799731231177316"},"PeriodicalIF":4.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191828/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9577599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of a pulmonary rehabilitation program combined with cognitive training on exercise tolerance and cognitive functions among Tunisian male patients with chronic obstructive pulmonary disease: A randomized controlled trial.","authors":"Oussama Tabka, Imen Sanaa, Marwa Mekki, Amal Acheche, Thierry Paillard, Yassine Trabelsi","doi":"10.1177/14799731231201643","DOIUrl":"10.1177/14799731231201643","url":null,"abstract":"<p><strong>Background: </strong>Cognitive impairment has been well described in patients with Chronic Obstructive Pulmonary Disease (COPD) in addition to cardiorespiratory disability. To reduce this impairment, researchers have recommended the use of single or combined exercise training. However, the combined effect of cognitive training (CT) and pulmonary rehabilitation (PR) program on selective cognitive abilities in patients with COPD has not been fully evaluated. Therefore, we aimed to assess the impact of PR combined with CT on 6 minutes walking test (6MWT) and cognitive parameters in Tunisian males' patients with COPD.</p><p><strong>Methods: </strong>Thirty-nine patients with COPD were randomly assigned to an intervention group (<i>n</i> = 21, age = 65.3 ± 2.79) and a control group (<i>n</i> = 18, age = 65.3 ± 3.2). The intervention group underwent PR combined with CT, and the control group underwent only PR, three times per week for 3 months. The primary outcomes were 6MWT (6 minutes walking test -6MWT-parameters) and cognitive performance, as evaluated by Montreal cognitive assessments (MOCA) and P300 test. Secondary outcomes were patient's characteristics and spirometric data. These tests were measured at baseline and after 3 months of training programs.</p><p><strong>Results: </strong>Results showed a significant improvement of the 6MWT distance after the rehabilitation period in both groups (<i>p</i> < .001). Moreover, both groups showed significant improvement (<i>p</i> < .001) in cognitive performance including MOCA score and P300 test latency in three midline electrodes. However, the improvement in cognitive performance was significantly greater in the PR+CT group than the PR group.</p><p><strong>Conclusion: </strong>In conclusion, although PR alone improves 6MWT parameters and cognitive function, the addition of CT to PR is more effective in improving cognitive abilities in patients with COPD. This combined approach may provide clinicians with a complementary therapeutic option for improving cognitive abilities in patients with COPD.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"20 ","pages":"14799731231201643"},"PeriodicalIF":3.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2d/3b/10.1177_14799731231201643.PMC10494516.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10587202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Australian airway clearance services for adults with chronic lung conditions: A national survey.","authors":"Laura Cooper,&nbsp;Kylie Johnston,&nbsp;Marie Williams","doi":"10.1177/14799731221150435","DOIUrl":"https://doi.org/10.1177/14799731221150435","url":null,"abstract":"<p><strong>Background: </strong>Physiotherapy-led airway clearance interventions are indicated for some people with chronic lung conditions. This study describes Australian clinical models for the provision of adult airway clearance services.</p><p><strong>Methods: </strong>This cross-sectional national study recruited public and private health care providers (excluding cystic fibrosis-specific services) identified by a review of websites. Providers were invited to complete an electronic 61-item survey with questions about airway clearance service context, referral demographics, service provision and program metrics. Data were reported descriptively with differences between metropolitan and non-metropolitan services explored with chi-square tests.</p><p><strong>Results: </strong>Between October-December 2019, the survey was disseminated to 131 providers with 91 responses received (69% response rate; 87 (96%) public (34 metropolitan; 53 non-metropolitan) and 4 (4%) private). Intent (chronic condition self-management) and types of intervention provided (education, breathing techniques, exercise prescription) were common across all services. Geographic location was associated with differences in airway clearance service models (greater use of regular clinics, telephone/telehealth consultations and dedicated cardiorespiratory physiotherapists in metropolitan locations versus clients incurring service and device provision costs in non-metropolitan regions).</p><p><strong>Conclusions: </strong>While similarities in airway clearance interventions exist, differences in service models may disadvantage people living with chronic lung conditions, especially in non-metropolitan regions of Australia.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"20 ","pages":"14799731221150435"},"PeriodicalIF":4.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5d/d8/10.1177_14799731221150435.PMC9903021.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10674650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term mechanical ventilation and transitions in care: A narrative review.","authors":"Lena Xiao,&nbsp;Reshma Amin,&nbsp;Mika Laura Nonoyama","doi":"10.1177/14799731231176301","DOIUrl":"10.1177/14799731231176301","url":null,"abstract":"<p><strong>Objectives: </strong>Individuals dependent on long-term mechanical ventilation (LTMV) for their day-to-day living are a heterogenous population who go through several transitions over their lifetime. This paper describes three transitions: 1) institution/hospital to community/home, 2) pediatric to adult care, and 3) active treatment to end-of-life for ventilator-assisted individuals (VAIs).</p><p><strong>Methods: </strong>A narrative review based on literature and the author's collective practical and research experience. Four online databases were searched for relevant articles. A manual search for additional articles was completed and the results are summarized.</p><p><strong>Results: </strong>Transitions from hospital to home, pediatric to adult care, and to end-of-life for VAIs are complex and challenging processes. Although there are several LTMV clinical practice guidelines highlighting key components for successful transition, there still exists gaps and inconsistencies in care. Most of the literature and experiences reported to date have been in developed countries or geographic areas with funded healthcare systems.</p><p><strong>Conclusions: </strong>For successful transitions, the VAIs and their support network must be front-and-center. There should be a coordinated, systematic, and holistic plan (including a multi-disciplinary team), life-time follow-up, with bespoke consideration of jurisdiction and individual circumstances.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"20 ","pages":"14799731231176301"},"PeriodicalIF":4.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4c/dd/10.1177_14799731231176301.PMC10184211.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9476145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical validation of a wearable respiratory rate device: A brief report.","authors":"Arik Eisenkraft,&nbsp;Nir Goldstein,&nbsp;Arik Ben Ishay,&nbsp;Meir Fons,&nbsp;Michael Tabi,&nbsp;Anna Danielle Sherman,&nbsp;Roei Merin,&nbsp;Dean Nachman","doi":"10.1177/14799731231198865","DOIUrl":"10.1177/14799731231198865","url":null,"abstract":"<p><strong>Background: </strong>Respiratory rate (RR) is used for the diagnosis and management of medical conditions and can predict clinical changes. Heavy workload, understaffing, and errors related to poor recording make it underutilized. Wearable devices may facilitate its use.</p><p><strong>Methods: </strong>RR measurements using a wearable photoplethysmography-based monitor were compared with medical grade devices in complementary clinical scenarios: Study one included a comparison to a capnograph in 35 healthy volunteers; Study two included a comparison to a ventilator monitor in 18 ventilated patients; and Study three included a comparison to capnograph in 92 COVID-19 patients with active pulmonary disease. Pearson's correlations and Bland-Altman analysis were used to assess the accuracy and agreement between the measurement techniques, including stratification for Body Mass Index (BMI) and skin tone. Statistical significance was set at <i>p</i> ≤ 0.05.</p><p><strong>Results: </strong>High correlation was found in all studies (r = 0.991, 0.884, and 0.888, respectively, <i>p</i> < 0.001 for all). 95% LOA of ±2.3, 1.7-(-1.6), and ±3.9 with a bias of < 0.1 breaths per minute was found in Bland-Altman analysis in studies 1,2, and 3, respectively. In all, high accordance was found in all sub-groups.</p><p><strong>Conclusions: </strong>RR measurements using the wearable monitor were highly-correlated with medical-grade devices in various clinical settings.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov, https://clinicaltrials.gov/ct2/show/NCT03603860.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"20 ","pages":"14799731231198865"},"PeriodicalIF":4.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7b/d9/10.1177_14799731231198865.PMC10461800.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10103630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}