Chronic Respiratory Disease最新文献

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Palliation, end of life care and ventilation withdrawal in neuromuscular disorders. 神经肌肉疾病的姑息、临终关怀和停止通气。
IF 4.1 3区 医学
Chronic Respiratory Disease Pub Date : 2023-01-01 DOI: 10.1177/14799731231175911
Joanna Elverson, Hayley Evans, Felicity Dewhurst
{"title":"Palliation, end of life care and ventilation withdrawal in neuromuscular disorders.","authors":"Joanna Elverson,&nbsp;Hayley Evans,&nbsp;Felicity Dewhurst","doi":"10.1177/14799731231175911","DOIUrl":"https://doi.org/10.1177/14799731231175911","url":null,"abstract":"<p><strong>Background/objectives: </strong>The role of palliative care in the support of patients with neuromuscular disorders (NMDs) is generally recognised in spite of the scarcity of condition-specific evidence in the literature.</p><p><strong>Methods: </strong>We have focussed specifically on palliative and end-of-life care for patients whose neuromuscular disease has an impact on their respiratory function. Reviewing the literature, we have examined where existing palliative care knowledge can be applied to the specific challenges faced by patients with NMDs, identifying where lessons learnt during the management of one condition may need to be judiciously applied to others.</p><p><strong>Results: </strong>We highlight lessons for clinical practice centring on six themes: management of complex symptoms; crisis support; relief of caregiver strain; coordination of care; advance care planning; and end of life care.</p><p><strong>Conclusions: </strong>The principles of palliative care are well suited to addressing the complex needs of patients with NMDs and should be considered early in the course of illness rather than limited to care at the end of life. Embedding relationships with specialist palliative care services as part of the wider neuromuscular multidisciplinary team can facilitate staff education and ensure timely referral when more complex palliative care problems arise.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"20 ","pages":"14799731231175911"},"PeriodicalIF":4.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/18/50/10.1177_14799731231175911.PMC10201157.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9580625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Changes in lung cancer staging and emergency presentations during the first year of the COVID-19 pandemic. 新冠肺炎大流行第一年癌症分期和急诊情况的变化。
IF 4.1 3区 医学
Chronic Respiratory Disease Pub Date : 2023-01-01 DOI: 10.1177/14799731231157770
Claire Vella, Wadood Parvez, Asif Ashraf, Syed Ajmal, Rajini Sudhir, Sanjay Agrawal, Jonathan Bennett, Muhammad Tufail
{"title":"Changes in lung cancer staging and emergency presentations during the first year of the COVID-19 pandemic.","authors":"Claire Vella,&nbsp;Wadood Parvez,&nbsp;Asif Ashraf,&nbsp;Syed Ajmal,&nbsp;Rajini Sudhir,&nbsp;Sanjay Agrawal,&nbsp;Jonathan Bennett,&nbsp;Muhammad Tufail","doi":"10.1177/14799731231157770","DOIUrl":"10.1177/14799731231157770","url":null,"abstract":"<p><p><b>Aim</b>: This study retrospectively analyses the impact of the 1<sup>st</sup> year of the COVID-19 pandemic on route of presentation and staging in lung cancer compared to the 2 years before and after implementation of the Leicester Optimal Lung Cancer Pathway (LOLCP) in Leicester, United Kingdom. <b>Method</b>: Electronic databases and hospital records were used to identify all patients diagnosed with lung cancer in 2018 (pre-LOLCP), 2019 (post-LOLCP), and March 2020-2021 (post-COVID-19 lockdown). Information regarding patient characteristics, performance status, stage, and route of diagnosis was documented and analysed. Emergency presentation was defined as diagnosis of new lung cancer being made after unscheduled attendance to urgent or emergency care facility. <b>Results</b>: Following implementation of the LOLCP pathway, there was a significant decrease in emergency presentations from 26.8 to 19.6% (<i>p</i> = 0.002) with a stage shift from 33.9% early stage disease to 40.3%. These improved outcomes were annulled during the COVID-19 pandemic, with emergency presentations increasing to 38.9% (<i>p</i> < 0.001) and a reduction in early-stage lung cancer diagnoses to 31.5%. There was a 61% decline in 2 week wait referrals but no significant decline in the LOLCP direct-to-CT referrals. <b>Conclusion</b>: We have demonstrated a significant increase in late-stage lung cancer diagnoses and emergency presentations during the first year of the COVID-19 pandemic. The causes for these changes are likely to be multifactorial. The long-term effect on lung cancer mortality remains to be seen and is an important focus of future study.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"20 ","pages":"14799731231157770"},"PeriodicalIF":4.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/00/80/10.1177_14799731231157770.PMC10422907.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9997433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterising hospitalisation risk for chronic obstructive pulmonary disease exacerbations: Bedside and outpatient clinic assessments of easily measured variables. 慢性阻塞性肺病恶化的住院风险特征:易测变量的床边和门诊评估。
IF 4.1 3区 医学
Chronic Respiratory Disease Pub Date : 2023-01-01 DOI: 10.1177/14799731231211852
Joshua Heerema, Sarah Hug, Natasha Bear, Kylie Hill
{"title":"Characterising hospitalisation risk for chronic obstructive pulmonary disease exacerbations: Bedside and outpatient clinic assessments of easily measured variables.","authors":"Joshua Heerema, Sarah Hug, Natasha Bear, Kylie Hill","doi":"10.1177/14799731231211852","DOIUrl":"10.1177/14799731231211852","url":null,"abstract":"<p><strong>Objective: </strong>To identify the characteristics of people with chronic obstructive pulmonary disease (COPD) who require hospitalisation for exacerbations.</p><p><strong>Methods: </strong>People with COPD were recruited either during hospitalisation or from out-patient respiratory medicine clinics. Hospital admissions were tracked throughout the 5-months recruitment period. For participants who were admitted, hospital readmissions were tracked for at least 30 days following discharge. Participants were grouped as either needing; (i) no hospital admission during the study period (no admission; ø-A), (ii) one or more hospital admissions during the study period but no readmission within 30 days of discharge (no rapid readmission; ø-RR) or (iii) one or more hospital admissions with a readmission within 30 days of discharge (rapid readmission; RR).</p><p><strong>Results: </strong>Compared with the ø-A group (<i>n</i>=211), factors that independently increased the risk of ø-RR (<i>n</i>=146) and/or RR (<i>n</i>=57) group membership were being aged >60 years, identifying as an Indigenous person (relative risk ratio, 95% confidence interval 7.8 [1.8 to 34.0]) and the use of a support person or community service for activities of daily living (1.5 [1.0 to 2.4]. A body mass index ≥25 kg/m<sup>2</sup> was protective.</p><p><strong>Conclusions: </strong>Variables recorded at the bedside or in clinic provided information on hospitalisation risk.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"20 ","pages":"14799731231211852"},"PeriodicalIF":4.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631319/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71478662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Translation, cross-cultural adaptation, reliability, and construct validity of the Brazilian Portuguese version of the Basic Psychological Needs in Exercise Scale. 巴西葡萄牙语版《运动基本心理需求量表》的翻译、跨文化适应、信度和结构有效性。
IF 4.1 3区 医学
Chronic Respiratory Disease Pub Date : 2023-01-01 DOI: 10.1177/14799731231183445
Manuela Karloh, Simone G Gavenda, Juliana Araújo, Hellen F Alexandre, Isabela Jcs Silva, Aline A Gulart, Anelise B Munari, Symeon P Vlachopoulos, Thiago S Matias, Anamaria F Mayer
{"title":"Translation, cross-cultural adaptation, reliability, and construct validity of the Brazilian Portuguese version of the Basic Psychological Needs in Exercise Scale.","authors":"Manuela Karloh, Simone G Gavenda, Juliana Araújo, Hellen F Alexandre, Isabela Jcs Silva, Aline A Gulart, Anelise B Munari, Symeon P Vlachopoulos, Thiago S Matias, Anamaria F Mayer","doi":"10.1177/14799731231183445","DOIUrl":"10.1177/14799731231183445","url":null,"abstract":"<p><strong>Results: </strong>59 patients were included (61% with COPD and 39% with ILD). BPNES factor scores were not significantly different between raters' assessments (<i>p</i> > 0.05). The internal consistency was 0.70 for autonomy, 0.76 for competence, and 0.80 for relatedness. Inter-rater and test-retest reliability were good to very good for autonomy (ICC = 0.78, 95%CI 0.62-0.87; ICC = 0.75, 95%CI 0.57-0.86, respectively), competence (ICC = 0.81, 95%CI 0.68-0.89; ICC = 0.65, 95%CI 0.43-0.80, respectively), and relatedness (ICC = 0.79, 95%CI 0.65-0.88; ICC = 0.70, 95%CI 0.50-0.83, respectively). Significant correlations were observed between BPNES factors and quality of life, anxiety, depression, and functional status. In conclusion, this study confirmed the reliability and construct validity of the Brazilian Portuguese version of the BPNES in patients with COPD and ILD.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"20 ","pages":"14799731231183445"},"PeriodicalIF":4.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631317/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71478663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of health-related quality of life measures in asthma-COPD overlap. 哮喘COPD患者健康相关生活质量指标的比较。
IF 4.1 3区 医学
Chronic Respiratory Disease Pub Date : 2023-01-01 DOI: 10.1177/14799731231215093
Meishan Liu, Xuwen Yang, Ying Wang, Yong Lu, Lirong Liang, Hong Zhang, Kewu Huang
{"title":"Comparison of health-related quality of life measures in asthma-COPD overlap.","authors":"Meishan Liu, Xuwen Yang, Ying Wang, Yong Lu, Lirong Liang, Hong Zhang, Kewu Huang","doi":"10.1177/14799731231215093","DOIUrl":"10.1177/14799731231215093","url":null,"abstract":"<p><strong>Objective: </strong>The Asthma Quality of Life Questionnaire (AQLQ) and COPD assessment test (CAT) are used to assess the health status of asthma and chronic obstructive pulmonary disease (COPD), respectively. However, whether these questionnaires are appropriate in patients with asthma-COPD overlap (ACO) has not been reported. This study aimed to evaluate the performance of the AQLQ and CAT in subjects with ACO.</p><p><strong>Methods: </strong>Subjects were enrolled from two previously described observational studies in Beijing, China. ACO was defined by a consensus definition from a roundtable discussion. All subjects completed the AQLQ, CAT, St George's Respiratory Questionnaire (SGRQ), pulmonary function tests, and the Asthma Control Questionnaire (ACQ)-5. Cross-sectional construct validity was evaluated by correlating the AQLQ and CAT with SGRQ score and other measures of asthma and COPD severity.</p><p><strong>Results: </strong>147 subjects with ACO were recruited. There were floor effects on non-respiratory components of the CAT, and ceiling effects on emotion domains of the AQLQ. Both questionnaires were significantly correlated with ACQ-5 score but were not correlated with FEV<sub>1</sub>% predicted or FVC% predicted. The AQLQ and CAT were strongly correlated with SGRQ score (r = -0.657 and r = 0.623, respectively). Multivariable linear regression analysis showed that the AQLQ (standardized β-coefficient = -0.449, <i>p</i> < .001) had a stronger association with SGRQ score compared with CAT (standardized β-coefficient = 0.211, <i>p</i> = .023).</p><p><strong>Discussion: </strong>The AQLQ and CAT were both valid for assessing the health-related quality of life in subjects with ACO, but the AQLQ performed better than CAT.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"20 ","pages":"14799731231215093"},"PeriodicalIF":4.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10640801/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72208635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development and implementation of the lung volume reduction pulmonary rehabilitation tool to identify eligibility for lung volume reduction in people with chronic obstructive pulmonary disease during pulmonary rehabilitation. 肺容量减少肺康复工具的开发和实施,以确定慢性阻塞性肺病患者在肺康复期间是否有资格进行肺容量减少。
IF 4.1 3区 医学
Chronic Respiratory Disease Pub Date : 2023-01-01 DOI: 10.1177/14799731231198863
Sara C Buttery, Parris J Williams, Lisa J Brighton, Craig Batista, Amy Dewar, Lauren Hogg, Karen Ingram, Gemma Korff, Maria Koulopoulou, Helen Lammin, Matthew Maddocks, Lynn McDonnell, Bhavin Mehta, Victoria Meyrick, Lisa Pritchard, Oliver Smith, Puja Trivedi, Rod A Lawson, Nicholas S Hopkinson
{"title":"Development and implementation of the lung volume reduction pulmonary rehabilitation tool to identify eligibility for lung volume reduction in people with chronic obstructive pulmonary disease during pulmonary rehabilitation.","authors":"Sara C Buttery,&nbsp;Parris J Williams,&nbsp;Lisa J Brighton,&nbsp;Craig Batista,&nbsp;Amy Dewar,&nbsp;Lauren Hogg,&nbsp;Karen Ingram,&nbsp;Gemma Korff,&nbsp;Maria Koulopoulou,&nbsp;Helen Lammin,&nbsp;Matthew Maddocks,&nbsp;Lynn McDonnell,&nbsp;Bhavin Mehta,&nbsp;Victoria Meyrick,&nbsp;Lisa Pritchard,&nbsp;Oliver Smith,&nbsp;Puja Trivedi,&nbsp;Rod A Lawson,&nbsp;Nicholas S Hopkinson","doi":"10.1177/14799731231198863","DOIUrl":"10.1177/14799731231198863","url":null,"abstract":"<p><strong>Background: </strong>Completion of pulmonary rehabilitation is recognised in chronic obstructive pulmonary disease (COPD) guidelines as a key opportunity to consider systematically whether a respiratory review to assess potential suitability for a lung volume reduction (LVR) procedure might be appropriate. We describe the development of a simple decision-support tool (the LVR-PR tool) to aid clinicians working in pulmonary rehabilitation, to operationalise this process.</p><p><strong>Methods: </strong>We took an iterative mixed methods approach, which was partnership-based and involved an initial consensus survey, focus groups and an observational study cohort at multiple pulmonary rehabilitation centres.</p><p><strong>Results: </strong>Diagnosis (97%), exercise capacity (84%), breathlessness (78%) and co-morbidities (76%) were acknowledged to be essential items for assessing basic LVR eligibility. Collating prior investigations and assessing patient understanding were considered useful but not essential. Clinician concerns included; streamlining the tool; access to clinical information and investigations; and care needed around introducing LVR therapies to patients in a PR setting. Access to clearer information about LVR procedures, the clinician's role in considering eligibility and how educational resources should be delivered were identified as important themes from patient group discussions. The LVR-PR tool was considered to be feasible and valid for implementation in a variety of PR services across the UK subject to the provision of appropriate health professional training. Clinicians working in specialist LVR centres across the UK who were not otherwise involved in the development process confirmed the tool's validity using the content validity index (CVI).</p><p><strong>Interpretation: </strong>The LVR-PR tool appears to be an acceptable tool that can be feasibly implemented in PR services subject to good quality educational resources for both patients and healthcare professionals.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"20 ","pages":"14799731231198863"},"PeriodicalIF":4.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4e/3f/10.1177_14799731231198863.PMC10475255.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10161448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reflecting on the importance of theory-informed qualitative research in people with chronic respiratory disease and their carers. 反思对慢性呼吸系统疾病患者及其护理人员进行理论知情定性研究的重要性。
IF 4.1 3区 医学
Chronic Respiratory Disease Pub Date : 2023-01-01 DOI: 10.1177/14799731231185128
Emma L Giles, Samantha L Harrison
{"title":"Reflecting on the importance of theory-informed qualitative research in people with chronic respiratory disease and their carers.","authors":"Emma L Giles,&nbsp;Samantha L Harrison","doi":"10.1177/14799731231185128","DOIUrl":"https://doi.org/10.1177/14799731231185128","url":null,"abstract":"Theory can be de fi ned as “ a formal logical explanation of some events that includes predictions of how things relate to one another. ” 1 Theory can be used in research in many ways. It can be used to help craft, develop","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"20 ","pages":"14799731231185128"},"PeriodicalIF":4.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288393/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10087276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Physical activity in idiopathic pulmonary fibrosis: Longitudinal change and minimal clinically important difference. 特发性肺纤维化患者的体育锻炼:纵向变化和最小临床重要性差异。
IF 4.1 3区 医学
Chronic Respiratory Disease Pub Date : 2023-01-01 DOI: 10.1177/14799731231221818
Kazuya Shingai, Toshiaki Matsuda, Yasuhiro Kondoh, Tomoki Kimura, Kensuke Kataoka, Toshiki Yokoyama, Yasuhiko Yamano, Tomoya Ogawa, Fumiko Watanabe, Jun Hirasawa, W Darlene Reid, Ryo Kozu
{"title":"Physical activity in idiopathic pulmonary fibrosis: Longitudinal change and minimal clinically important difference.","authors":"Kazuya Shingai, Toshiaki Matsuda, Yasuhiro Kondoh, Tomoki Kimura, Kensuke Kataoka, Toshiki Yokoyama, Yasuhiko Yamano, Tomoya Ogawa, Fumiko Watanabe, Jun Hirasawa, W Darlene Reid, Ryo Kozu","doi":"10.1177/14799731231221818","DOIUrl":"10.1177/14799731231221818","url":null,"abstract":"<p><strong>Background and objective: </strong>Reference values of physical activity to interpret longitudinal changes are not available in patients with idiopathic pulmonary fibrosis (IPF). This study aimed to define the minimal clinical important difference (MCID) of longitudinal changes in physical activity in patients with IPF.</p><p><strong>Methods: </strong>Using accelerometry, physical activity (steps per day) was measured and compared at baseline and 6-months follow-up in patients with IPF. We calculated MCID of daily step count using multiple anchor-based and distribution-based methods. Forced vital capacity and 6-minute walk distance were applied as anchors in anchor-based methods. Effect size and standard error of measurement were used to calculate MCID in distribution-based methods.</p><p><strong>Results: </strong>One-hundred and five patients were enrolled in the study (mean age: 68.5 ± 7.5 years). Step count significantly decreased from baseline to 6-months follow-up (-461 ± 2402, <i>p</i> = .031). MCID calculated by anchor-based and distribution-based methods ranged from 570-1358 steps.</p><p><strong>Conclusion: </strong>Daily step count significantly declined over 6-months in patients with IPF. MCID calculated by multiple anchor-based and distribution-based methods was 570 to 1358 steps/day. These findings contribute to interpretation of the longitudinal changes of physical activity that will assist its use as a clinical and research outcome in patients with IPF.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"20 ","pages":"14799731231221818"},"PeriodicalIF":4.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138799460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tidal volume expandability and ventilatory efficiency as predictors of mortality in Taiwanese male patients with chronic obstructive pulmonary disease: A 10-year follow-up study - Is V̇O2peak or FEV1% the gold standard? 潮气量膨胀性和通气效率是台湾男性慢性阻塞性肺病患者死亡率的预测因素:一项为期 10 年的随访研究 - V̇O2peak 或 FEV1% 是金标准吗?
IF 4.1 3区 医学
Chronic Respiratory Disease Pub Date : 2023-01-01 DOI: 10.1177/14799731231220675
Ming-Lung Chuang, Yu-Hsun Wang
{"title":"Tidal volume expandability and ventilatory efficiency as predictors of mortality in Taiwanese male patients with chronic obstructive pulmonary disease: A 10-year follow-up study - Is V̇O<sub>2peak</sub> or FEV<sub>1</sub>% the gold standard?","authors":"Ming-Lung Chuang, Yu-Hsun Wang","doi":"10.1177/14799731231220675","DOIUrl":"https://doi.org/10.1177/14799731231220675","url":null,"abstract":"<p><p>Despite our knowledge of the risk factors for mortality associated with chronic obstructive pulmonary disease (COPD), the mortality rate for this condition continues to increase. This study aimed to investigate the predictive power of physiological variables on all-cause mortality in COPD patients compared to peak oxygen uptake (<math><mrow><mover><mi>V</mi><mo>˙</mo></mover></mrow></math>O<sub>2peak</sub>) and forced expired volume in one second (FEV<sub>1</sub>). We conducted a retrospective study of 182 COPD patients with complete lung function tests, cardiopulmonary exercise testing (CPET), and survival data. Cox regression analysis was used to estimate the hazard ratios for all-cause mortality. The median follow-up period was 6.8 (IQR 3.9-9.2) years. Out of the 182 patients in our study, sixty-two (34.1%) succumbed to various causes. Of these, 27.4% (<i>n</i> = 17) experienced acute exacerbations, 24.2% (<i>n</i> = 15) had advanced cancer, and 12.9% (<i>n</i> = 8) had cardiovascular disease as the primary cause of death. Another 25.8% (<i>n</i> = 16) passed away due to other underlying conditions, while 6.5% (<i>n</i> = 4) had an unknown cause of death. One patient's demise was attributed to a benign tumor, and another's to a connective tissue disease. The ratio of tidal volume to total lung capacity (V<sub>Tpeak</sub>/TLC) and the ratio of minute ventilation and <math><mrow><mover><mi>V</mi><mo>˙</mo></mover></mrow></math>O<sub>2</sub> at nadir (<math><mrow><mover><mi>V</mi><mo>˙</mo></mover></mrow></math><sub>E</sub>/<math><mrow><mover><mi>V</mi><mo>˙</mo></mover></mrow></math>O<sub>2nadir</sub>) (AUR 0.83, 95% CI 0.76-0.91) were superior predictors of all-cause mortality compared to <math><mrow><mover><mi>V</mi><mo>˙</mo></mover></mrow></math>O<sub>2peak</sub> and FEV<sub>1</sub>%. A mortality prediction formula was derived using these variables. This study highlights the potential of V<sub>Tpeak</sub>/TLC and <math><mrow><mover><mi>V</mi><mo>˙</mo></mover></mrow></math><sub>E</sub>/<math><mrow><mover><mi>V</mi><mo>˙</mo></mover></mrow></math>O<sub>2nadir</sub> as predictive markers for COPD all-cause mortality in COPD. CPET is an effective tool for evaluating COPD mortality; however, the predictive equation requires further validation.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"20 ","pages":"14799731231220675"},"PeriodicalIF":4.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10722945/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138799463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A systematic review of exercise studies for individuals hospitalized with an acute exacerbation of chronic obstructive pulmonary disease: Focus on the principles of exercise training. 慢性阻塞性肺疾病急性加重住院患者运动研究的系统综述:关注运动训练的原则。
IF 4.1 3区 医学
Chronic Respiratory Disease Pub Date : 2023-01-01 DOI: 10.1177/14799731231215363
Débora Petry Moecke, Kai Zhu, Jagdeep Gill, Shanjot Brar, Polina Petlitsyna, Ashley Kirkham, Mirha Girt, Joel Chen, Hannah Peters, Holly Denson-Camp, Stephanie Crosbie, Pat G Camp
{"title":"A systematic review of exercise studies for individuals hospitalized with an acute exacerbation of chronic obstructive pulmonary disease: Focus on the principles of exercise training.","authors":"Débora Petry Moecke, Kai Zhu, Jagdeep Gill, Shanjot Brar, Polina Petlitsyna, Ashley Kirkham, Mirha Girt, Joel Chen, Hannah Peters, Holly Denson-Camp, Stephanie Crosbie, Pat G Camp","doi":"10.1177/14799731231215363","DOIUrl":"10.1177/14799731231215363","url":null,"abstract":"<p><strong>Background: </strong>For exercise interventions to be effectively reproduced or applied in a \"real world\" clinical setting, clinical trials must thoroughly document all components of the exercise prescription and ensure that participants adhere to each component. However, previous reviews have not critically examined the quality of exercise prescription of inpatient Pulmonary Rehabilitation (PR) programs.</p><p><strong>Objective: </strong>The objectives of this review were to evaluate the (a) application of the principles of exercise training, (b) reporting of the frequency, intensity, time and type (FITT) components of exercise prescription, and (c) reporting of patient's adherence to the FITT components in intervention studies for patients admitted to hospital for an acute exacerbation of chronic obstructive pulmonary disease (AECOPD).</p><p><strong>Methods: </strong>Relevant scientific databases were searched for randomized controlled trials (RCTs) that compared in-hospital PR with usual care for people hospitalized with AECOPD. Title and abstract followed by full-text screening were conducted independently by two reviewers. Data were extracted and synthesized to evaluate the application of the principles of exercise training and the reporting/adherence of the FITT components.</p><p><strong>Results: </strong>Twenty-seven RCTs were included. Only two applied all principles of exercise training. Specificity was applied by 70%, progression by 48%, overload by 37%, initial values by 89% and diminishing returns and reversibility by 37% of trials. Ten trials adequately reported all FITT components. Frequency and type were the components most reported (85% and 81%, respectively), while intensity was less frequently reported (52%). Only three trials reported on the patient's adherence to all four components.</p><p><strong>Conclusions: </strong>Studies have not adequately reported the exercise prescription in accordance with the principles of exercise training nor reported all the FITT components of the exercise prescription and patient's adherence to them. Therefore, interpretation of the current literature is limited and information for developing exercise prescriptions to individuals hospitalized with an AECOPD is lacking.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"20 ","pages":"14799731231215363"},"PeriodicalIF":4.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655651/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134648612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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