Circulation: Cardiovascular Imaging最新文献

{"title":"Platypnea-Orthodeoxia Syndrome After Esophageal Dilation in a Patient With a Dilated Ascending Aorta.","authors":"Matthew B Saunders, Matthew S Michaleski, Jeffrey Yim, Miles Marchand, John Jue, David A Wood, Christina L Luong, Michael Y C Tsang, Teresa S M Tsang, Darwin F Yeung","doi":"10.1161/CIRCIMAGING.124.016887","DOIUrl":"https://doi.org/10.1161/CIRCIMAGING.124.016887","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e016887"},"PeriodicalIF":6.5,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142361217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sudden Cardiac Arrest With Acute Myocardial Infarction Due to Myocardial Bridging and Hypertrophic Cardiomyopathy.","authors":"Yi-Ching Liu, Wei-Chung Tsai, Shu-Chien Huang, Min-Fang Chao, Shuenn-Nan Chiu, Yen-Hsien Wu, Shih-Hsing Lo, I-Chen Chen, Zen-Kong Dai, Jong-Hau Hsu","doi":"10.1161/CIRCIMAGING.124.016993","DOIUrl":"https://doi.org/10.1161/CIRCIMAGING.124.016993","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e016993"},"PeriodicalIF":6.5,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142361218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intraindividual Comparison of Ultrahigh-Spatial-Resolution Photon-Counting Detector CT and Energy-Integrating Detector CT for Coronary Stenosis Measurement.","authors":"Milán Vecsey-Nagy, Giuseppe Tremamunno, U Joseph Schoepf, Chiara Gnasso, Emese Zsarnóczay, Nicola Fink, Dmitrij Kravchenko, Moritz C Halfmann, Gerald S Laux, Jim O'Doherty, Bálint Szilveszter, Pál Maurovich-Horvat, Ismail Mikdat Kabakus, Pal Spruill Suranyi, Akos Varga-Szemes, Tilman Emrich","doi":"10.1161/CIRCIMAGING.124.017112","DOIUrl":"10.1161/CIRCIMAGING.124.017112","url":null,"abstract":"<p><strong>Background: </strong>A recent simulation study proposed that stenosis measurements on coronary computed tomography (CT) angiography are influenced by the improved spatial resolution of photon-counting detector (PCD)-CT. The aim of the current study was to evaluate the impact of ultrahigh-spatial-resolution (UHR) on coronary stenosis measurements and Coronary Artery Disease Reporting and Data System (CAD-RADS) reclassification rates in patients undergoing coronary CT angiography on both PCD-CT and energy-integrating detector (EID)-CT and to compare measurements against quantitative coronary angiography.</p><p><strong>Methods: </strong>Patients with coronary calcification on EID-CT (collimation, 192×0.6 mm) were prospectively enrolled for a research coronary CT angiography with UHR PCD-CT (collimation, 120×0.2 mm) within 30 days (between April 1, 2023 and January 31, 2024). PCD-CT was acquired with the same or lower CT dose index and equivalent contrast media volume as EID-CT. Percentage diameter stenosis (PDS) for calcified, partially calcified, and noncalcified lesions were compared between scanners. Patient-level reclassification rates for CAD-RADS were evaluated. The accuracy of PDS measurements was validated against quantitative coronary angiography in patients who underwent invasive coronary angiography.</p><p><strong>Results: </strong>In total, PDS of 278 plaques were quantified in 49 patients (calcified, 202; partially calcified, 51; noncalcified, 25). PCD-CT-based PDS values were lower than EID-CT measurements for calcified (45.1±20.7 versus 54.6±19.2%; <i>P</i><0.001) and partially calcified plaques (44.3±19.6 versus 54.9±20.0%; <i>P</i><0.001), without significant differences for noncalcified lesions (39.1±15.2 versus 39.0±16.0%; <i>P</i>=0.98). The reduction in stenosis degrees led to a 49.0% (24/49) reclassification rate to a lower CAD-RADS with PCD-CT. In a subset of 12 patients with 56 lesions, UHR-based PDS values showed higher agreement with quantitative coronary angiography (mean difference, 7.3%; limits of agreement, -10.7%/25.2%) than EID-CT measurements (mean difference, 17.4%; limits of agreement, -6.9%/41.7%).</p><p><strong>Conclusions: </strong>Compared with conventional EID-CT, UHR PCD-CT results in lower PDS values and more accurate stenosis measurements in coronary plaques with calcified components and leads to a substantial Coronary Artery Disease Reporting and Data System reclassification rate in 49.0% of patients.</p>","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e017112"},"PeriodicalIF":6.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142342713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coronary Plaque Characteristics in Patients With Chronic Kidney Failure: Impact on Cardiovascular Events and Mortality.","authors":"Jonathan Nørtoft Dahl, Marie B Nielsen, Laust D Rasmussen, Per Ivarsen, Michelle C Williams, My Hanna Sofia Svensson, Henrik Birn, Morten Bøttcher, Simon Winther","doi":"10.1161/CIRCIMAGING.124.017066","DOIUrl":"10.1161/CIRCIMAGING.124.017066","url":null,"abstract":"<p><strong>Background: </strong>In patients with coronary artery disease, coronary plaques with high-risk features and low-attenuation plaque burden are independent measures associated with major adverse cardiovascular events (MACEs). Patients with chronic kidney failure may have different coronary artery disease characteristics. The aim was to assess the association of coronary plaque characteristics and coronary artery disease extent with MACE and all-cause mortality in patients with chronic kidney failure.</p><p><strong>Methods: </strong>Potential kidney transplant candidates who underwent coronary computed tomography angiography as part of the cardiac screening program before kidney transplantation were included. We evaluated high-risk plaques and diameter stenosis semiqualitatively and quantified coronary artery calcium score and plaque burden (percentage atheroma volume).</p><p><strong>Results: </strong>In 484 patients with chronic kidney failure and few or no symptoms of coronary artery disease (mean age, 53±12 years; 62% men; 32% on dialysis), 56 (12%) patients suffered MACE and 69 (14%) patients died during a median follow-up of 4.9 years. High-risk plaques were present in 39 (70%) patients with MACE. Median calcified plaque burden was 3.7% in patients with MACE versus 0.2% in patients without MACE. The median low-attenuation plaque burden was 0.3% versus 0.03%, respectively. In semiqualitative analyses, the presence of high-risk plaque and a higher coronary artery calcium score were associated with increased risk of MACE (hazard ratio (HR), 2.0 [95% CI, 1.0-3.7]; <i>P</i>=0.040; HR, 1.2 [95% CI, 1.0-1.3]; <i>P</i>=0.014), respectively. Neither were associated with all-cause mortality. In quantified analysis, increasing levels of both calcified and low-attenuation plaque burdens were associated with risk of MACE (HR, 2.6 [95% CI, 1.8-3.7]; <i>P</i><0.001; HR, 2.6 [95% CI, 1.5-4.5]; <i>P</i>=0.001 [per variable doubling, respectively]) and all-cause mortality (HR, 1.6 [95% CI, 1.2-2.1]; <i>P</i>=0.002; HR, 1.8 [95% CI, 1.1-3.0]; <i>P</i>=0.028, respectively).</p><p><strong>Conclusions: </strong>In patients with chronic kidney failure, calcified and low-attenuation plaque burdens were independently associated with MACE and all-cause mortality, while high-risk plaques and coronary artery calcium score were only associated with MACE.</p><p><strong>Registration: </strong>URL: https://www.clinicaltrials.gov; Unique identifier: NCT01344434.</p>","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e017066"},"PeriodicalIF":6.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142342712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrafast Myocardial Contrast Echocardiography for the Assessment of Coronary Artery Disease: First In-Human Study.","authors":"Lasha Gvinianidze, Matthieu Toulemonde, Reinette Hampson, Biao Huang, Gabriel Bioh, Leigh-Ann Wakefield, Ashish Patel, Kiruba Rajan, Meng-Xing Tang, Roxy Senior","doi":"10.1161/CIRCIMAGING.124.017267","DOIUrl":"10.1161/CIRCIMAGING.124.017267","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e017267"},"PeriodicalIF":6.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11483224/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142361219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Defining Echocardiographic Degrees of Right Heart Size and Function in Pulmonary Vascular Disease from the PVDOMICS Study.","authors":"Monica Mukherjee, Stephen C Mathai, Christine Jellis, Benjamin H Freed, Lisa R Yanek, Hannah Agoglia, Caitlin Chiu, Vivek P Jani, Catherine E Simpson, Evan L Brittain, W H Wilson Tang, Margaret M Park, Anna R Hemnes, Erika B Rosenzweig, Franz P Rischard, Robert P Frantz, Paul M Hassoun, Gerald Beck, Nicholas S Hill, Serpil Erzurum, James D Thomas, Deborah Kwon, Jane A Leopold, Evelyn M Horn, Jiwon Kim","doi":"10.1161/circimaging.124.017074","DOIUrl":"10.1161/circimaging.124.017074","url":null,"abstract":"<p><strong>Background: </strong>Defining qualitative grades of echocardiographic metrics of right heart chamber size and function is critical for screening, clinical assessment, and measurement of therapeutic response in individuals with pulmonary vascular disease (PVD). In a population enriched for PVD, we sought to establish qualitative grades and prognostic value of right heart chamber size and function.</p><p><strong>Methods: </strong>We investigated 1053 study participants in the Redefining Pulmonary Hypertension through PVD Phenomics program (PVDOMICS) to determine clinical and echocardiographic differences associated with increasing pulmonary vascular resistance (PVR) severity. Right heart chamber size and function were qualitatively assessed using a percentile-based approach above the median values to create a clinical grading system for right heart adaptation. The relationship between echocardiographic categories and all-cause mortality was examined using survival analyses adjusted for potential confounders.</p><p><strong>Results: </strong>A stepwise increase in adverse right heart remodeling was observed with a concomitant decrease in functional parameters by PVR strata (p<0.001 for all). Mild, moderate, and severe categories of right heart chamber size and dysfunction were defined using a percentile-based approach across the spectrum of PVD. During a median follow up of 2.07 years (interquartile range 1.23 - 3.01 years), 130 participants died (11.4%). Progressive PVR increase and 2DE evidence of right heart dysfunction inclusive of fractional area change, and right ventricular (RV) global longitudinal strain were independently associated with increased all-cause mortality risk in multivariate analysis adjusted for age, disease duration and male sex.</p><p><strong>Conclusions: </strong>In this well-characterized sample of adults with diverse etiologies and varying PVD severity, we define categories of abnormal right heart chamber size and function. Further, we demonstrate a stepwise relationship between these categories of abnormal morphology and function and all-cause mortality. Defining grades of RV dysfunction in individuals with known PVD has important clinical implications for monitoring disease progression and response to therapies.</p>","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":"17 10","pages":""},"PeriodicalIF":6.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11649025/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142846022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Klebsiella Pneumoniae</i> Invasive Syndrome With Thoracic Aortic Pseudoaneurysm.","authors":"Kosuke Tsuda, Hideaki Morita, Chiaki Hikida, Kanako Akamatsu, Hideki Ozawa, Yumiko Kanzaki, Yoshihiko Arima, Hiroaki Uchida, Isao Morii, Masaya Kino, Takahiro Katsumata, Masaaki Hoshiga","doi":"10.1161/CIRCIMAGING.124.016668","DOIUrl":"10.1161/CIRCIMAGING.124.016668","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e016668"},"PeriodicalIF":6.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141466519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Mahmod et al, \"Differentiating Left Ventricular Remodeling in Aortic Stenosis From Systemic Hypertension\".","authors":"","doi":"10.1161/HCI.0000000000000085","DOIUrl":"https://doi.org/10.1161/HCI.0000000000000085","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":"17 10","pages":"e000085"},"PeriodicalIF":6.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142459379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atypical Subendocardial Late Gadolinium Enhancement in Anderson-Fabry Cardiomyopathy.","authors":"Raffaello Ditaranto, Chiara Chiti, Agnese Milandri, Francesco Lai, Luigi Lovato, Maddalena Graziosi, Francesca Graziani, Maurizio Pieroni, Francesco Cappelli, Giuseppe Limongelli, Iacopo Olivotto, Elena Biagini","doi":"10.1161/CIRCIMAGING.124.016865","DOIUrl":"10.1161/CIRCIMAGING.124.016865","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e016865"},"PeriodicalIF":6.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141589760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient-Specific Myocardial Infarction Risk Thresholds From AI-Enabled Coronary Plaque Analysis.","authors":"Robert J H Miller, Nipun Manral, Andrew Lin, Aakash Shanbhag, Caroline Park, Jacek Kwiecinski, Aditya Killekar, Priscilla McElhinney, Hidenari Matsumoto, Aryabod Razipour, Kajetan Grodecki, Alan C Kwan, Donghee Han, Keiichiro Kuronuma, Guadalupe Flores Tomasino, Jolien Geers, Markus Goeller, Mohamed Marwan, Heidi Gransar, Balaji K Tamarappoo, Sebastien Cadet, Victor Y Cheng, Stephan Achenbach, Stephen J Nicholls, Dennis T Wong, Lu Chen, J Jane Cao, Daniel S Berman, Marc R Dweck, David E Newby, Michelle C Williams, Piotr J Slomka, Damini Dey","doi":"10.1161/CIRCIMAGING.124.016958","DOIUrl":"10.1161/CIRCIMAGING.124.016958","url":null,"abstract":"<p><strong>Background: </strong>Plaque quantification from coronary computed tomography angiography has emerged as a valuable predictor of cardiovascular risk. Deep learning can provide automated quantification of coronary plaque from computed tomography angiography. We determined per-patient age- and sex-specific distributions of deep learning-based plaque measurements and further evaluated their risk prediction for myocardial infarction in external samples.</p><p><strong>Methods: </strong>In this international, multicenter study of 2803 patients, a previously validated deep learning system was used to quantify coronary plaque from computed tomography angiography. Age- and sex-specific distributions of coronary plaque volume were determined from 956 patients undergoing computed tomography angiography for stable coronary artery disease from 5 cohorts. Multicenter external samples were used to evaluate associations between coronary plaque percentiles and myocardial infarction.</p><p><strong>Results: </strong>Quantitative deep learning plaque volumes increased with age and were higher in male patients. In the combined external sample (n=1847), patients in the ≥75th percentile of total plaque volume (unadjusted hazard ratio, 2.65 [95% CI, 1.47-4.78]; <i>P</i>=0.001) were at increased risk of myocardial infarction compared with patients below the 50th percentile. Similar relationships were seen for most plaque volumes and persisted in multivariable analyses adjusting for clinical characteristics, coronary artery calcium, stenosis, and plaque volume, with adjusted hazard ratios ranging from 2.38 to 2.50 for patients in the ≥75th percentile of total plaque volume.</p><p><strong>Conclusions: </strong>Per-patient age- and sex-specific distributions for deep learning-based coronary plaque volumes are strongly predictive of myocardial infarction, with the highest risk seen in patients with coronary plaque volumes in the ≥75th percentile.</p>","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":"17 10","pages":"e016958"},"PeriodicalIF":6.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142459381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}