中华创伤杂志最新文献

{"title":"Research progress in effect of surgical timing on postoperative mortality in elderly patients with hip fracture","authors":"Yueyang You, K. Sun, M. Yan","doi":"10.3760/CMA.J.ISSN.1001-8050.2020.01.012","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1001-8050.2020.01.012","url":null,"abstract":"Hip fracture is a common type of fracture in the elderly. Complications such as pulmonary infection, pressure sore, deep vein thrombosis or pulmonary embolism often occurred after hip fracture, which may threaten the lives of patients. At present, surgery is the main measure for hip fracture, including joint replacement and internal fixation. The impact of surgical timing on postoperative mortality is the focus of attention of many scholars. However, there is still no consistent conclusion, and clinicians are often confused. The authors review the definition of surgical timing, the impact of surgical timing on mortality and process improvement in surgical timing in order to better guide clinical practice and provide new ideas for clinical research. \u0000 \u0000 \u0000Key words: \u0000Hip fractures; Aged; Mortality; Surgical timing","PeriodicalId":10161,"journal":{"name":"Chinese Journal of Trauma","volume":"36 1","pages":"58-62"},"PeriodicalIF":0.0,"publicationDate":"2020-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48599770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Construction and application of information platform for pre-hospital and in-hospital synergic treatment in trauma emergency center","authors":"Jianjun Cai, Yuhua Wan, Yuanlin Zeng, Haiming Chen","doi":"10.3760/CMA.J.ISSN.1001-8050.2020.01.017","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1001-8050.2020.01.017","url":null,"abstract":"In order to provide timely and effective treatment and reduce the rate of death and disability for trauma patients, the National Health Construction Commission issued a document to promote the construction of trauma centers and achieve centralized hospitalization for trauma patients. Pre-hospital first aid is the most important part of the modern emergency medical system, and it is especially important for the successful treatment of trauma patients. In order to achieve close coordination, efficient docking, emergency clinic advancement in the front yard, and improve the success rate of trauma patients, Nanchang Emergency Center proposed an integrated treatment mode for pre-hospital first aid and trauma emergency center, and developed a pre-hospital collaborative treatment information platform. The authors explore the application of the information platform in the integrated treatment mode of pre-hospital first aid and trauma emergency center and realize information sharing in the front yard of trauma patients, pre-hospital teleconsultation and seamless docking in the front yard, so as to provide a foundation for fast, efficient and full-coverage medical treatment system for trauma. \u0000 \u0000 \u0000Key words: \u0000Emergency medicine; Emergency medical services; Trauma emergency centers","PeriodicalId":10161,"journal":{"name":"Chinese Journal of Trauma","volume":"36 1","pages":"82-85"},"PeriodicalIF":0.0,"publicationDate":"2020-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42837935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of argatroban in repair of spinal cord injury in rats","authors":"Chenxi Zhao, Baoyou Fan, Wenxiang Li, Xu Wang, Yilin Pang, Xue Yao, S. Feng","doi":"10.3760/CMA.J.ISSN.1001-8050.2020.01.018","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1001-8050.2020.01.018","url":null,"abstract":"Objective \u0000To investigate the effect of argatroban in repair of spinal cord injury in rats. \u0000 \u0000 \u0000Methods \u0000A total of 54 female Wistar rats were selected and divided into three groups according to the random number table: sham group, injury group and Argatroban group, with 18 rats in each group. The sham group only took the T10lamina; the injury group used the spinal cord injury device to make the rat spinal cord injury model; the Argatroban group received Argatroban treatment after spinal cord injury. The recovery of hindlimb motor function was evaluated by BBB score and clined plate test before injury and 7, 14, 21, 28, 35 and 42 days after injury. The sensory evoked potentials (SEP) and motor evoked potentials (MEP) were detected 42 days after operation. HE staining was used to compare the size of the cavity in the local region 42 days after injury. \u0000 \u0000 \u0000Results \u0000At day 7 after injury, the BBB score was (3.7±0.5)points and the inclined plane test was (28.0±2.6)° in the Argatroban group, which were better than those in the injury group [(3.3±0.5)points, (24.3±1.9)°] (P<0.05). At day 42 after injury, the BBB score was (13.0±0.8)points and inclined plane test was (50.7±2.7)° in the Argatroban group, which were significantly better than those in the injury group [(9.7±1.3) points, (40.5±2.7)°] (P<0.05). But all the above values in the Argatroban group were significantly lower than those in the sham group [(21.0±0.0)points, (60.0±0.0)°](P<0.05). At day 42 after operation, the SEP latency [(25.0±0.9)ms] in the Argatroban group was significantly shorter than that in the injury group [(31.5±1.9) ms]; the amplitude [(2.1±0.1)μV] in the Argatroban group was lower than that in the injury group [(0.5±0.1)μV] (P<0.05). The MEP latency [(11.5±1.0)ms] in the Argatroban group was significantly shorter than that in the injury group [(17.5±1.1)ms], and the amplitude [(4.8±0.8)μV] in the Argatroban group was lower than that in the injury group [(2.8±0.7)μV] (P<0.05). And the SEP or MEP latency and amplitude in the Argatroban group showed significant differences compared to the sham group [(7.5±1.0)ms, (7.5±1.0)μV](P<0.05). HE staining showed that the central area of the lesion in the Argatroban group [(0.35±0.04)mm2] was significantly smaller than that in the injury group [(0.71±0.05)mm2]. \u0000 \u0000 \u0000Conclusion \u0000After spinal cord injury, argatroban can protect the spinal cord tissue effectively in the injured area and promote recovery of sensory and motor function in the hind limbs of rats. \u0000 \u0000 \u0000Key words: \u0000Spinal cord injuries; Argatroban; Inflammation; Thrombin","PeriodicalId":10161,"journal":{"name":"Chinese Journal of Trauma","volume":"36 1","pages":"86-92"},"PeriodicalIF":0.0,"publicationDate":"2020-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44219264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of bone grafting in the injured vertebrae combined with pedicle screw-rod system assisted with drugs in treating lumbar vertebral compression fracture in the elderly","authors":"Wu Zhou, T. Xia, Faqi Cao, Jing Liu, Liangcong Hu, Mengfei Liu, Qisheng Zhou, Guohui Liu","doi":"10.3760/CMA.J.ISSN.1001-8050.2020.01.007","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1001-8050.2020.01.007","url":null,"abstract":"Objective \u0000To explore the clinical effect of bone grafting in the injured vertebrae combined with pedicle screw-rod system assisted with drugs in treating lumbar vertebral compression fracture in the elderly. \u0000 \u0000 \u0000Methods \u0000A retrospective case-control study was carried out to analyze the clinical data of 48 cases of lumbar vertebral compression fracture in the elderly admitted to the Union Hospital between October 2015 and October 2018. There were 34 males and 14 females, aged 60-78 years [(62.8±2.5)years]. Segment of injury was L1 in 37 cases, L2 in 7, L3 in 2, and L4 in 4. There were 20 cases in bone grafting group involving 15 males and five females, aged from 60 to 78 years [(63.7±2.1)years]. There were 28 cases in non-bone grafting group involving 19 males and nine females, aged from 60 to 75 years [(62.4±2.9)years]. The Frankel scale in bone grafting group was grade D in 15 cases and grade E in 5, and in non-bone grafting group was grade D in 18 cases and grade E in 10. All the cases were treated by pedicle screw fixation combined with antiosteoporosis drugs, and the bone grafting group were treated by bone grafting via the injured vertebrae, but the other group were not. The intraoperative blood loss and operation time for each segmental vertebrae were recorded. The visual analogue scale (VAS) before operation and one year after operation, the bone healing at three months and one year postoperatively were recorded. The compression rate of the injured vertebrae at operation, at one day and one-year postoperatively as well as the height loss of the injured vertebrae at postoperative one year were measured. Spinal cord injury was also evaluated by Frankel scale. Wound healing, lower limb thrombosis, lung infection and ulcer were observed. \u0000 \u0000 \u0000Results \u0000All the cases were followed up, with duration for 12-25 months [(16.2±3.4)months] in bone grafting group and 15-24 months [(17.5±5.4)months] in non-bone grafting group (P>0.05). The blood loss was (240±70)ml in bone grafting group and (210±65)ml in non-bone grafting group (P>0.05). Screw implantation time for each segment was (38.5±9.6)minutes in bone grafting group and (30.5±5.4)minutes in non-bone grafting group (P 0.05). No significant difference was found in compression rate of the injured vertebral height between the two groups before and after operation (P>0.05). The height loss rate of the injured vertebrae was 3% (2%, 4%) at one year postoperatively in bone grafting group and 6% (5%, 8%) in non-bone grafting group (P 0.05). \u0000 \u0000 \u0000Conclusion \u0000For lumbar vertebral compression fracture in the elderly, bone grafting in the injured vertebrae combined with pedicle screw-rod system assisted with drugs is significantly better in recovering and maintaining the injured vertebrae height, relieving the pain and promoting the bone healing, although the screw implantation time is prolonged. \u0000 \u0000 \u0000Key words: \u0000Lumbar; Spinal fractures; Aged; Bone grafting","PeriodicalId":10161,"journal":{"name":"Chinese Journal of Trauma","volume":"36 1","pages":"24-30"},"PeriodicalIF":0.0,"publicationDate":"2020-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41865565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of constructing standardized and well-developed wound repair department in China","authors":"Xiaobing Fu","doi":"10.3760/CMA.J.ISSN.1001-8050.2020.01.002","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1001-8050.2020.01.002","url":null,"abstract":"Based on the spirit of the regulations about diagnosis and treatment of chronic skin wounds and its standardization for doctors and nurses just issued by National Health and Health Commission, the author offers his own understanding and comments about how to establish a well-developed wound repair department with Chinese characteristic in China in combining with their previous practice of exploring the establishment of a wound repair discipline system, and puts forward relevant suggestions for readers. \u0000 \u0000 \u0000Key words: \u0000Ulcer; Reconstructive surgical procedures; Wounds","PeriodicalId":10161,"journal":{"name":"Chinese Journal of Trauma","volume":"36 1","pages":"3-5"},"PeriodicalIF":0.0,"publicationDate":"2020-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42180730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research progress in effect of alendronate on healing of osteoporotic fracture","authors":"Yajun Wang, Chen Xiao, Xinli Zhi, S. Jiacan","doi":"10.3760/CMA.J.ISSN.1001-8050.2020.01.013","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1001-8050.2020.01.013","url":null,"abstract":"Fracture healing is a complex physiological process involving osteoblasts, osteoclasts and other cells and molecules. Typical fracture healing can be divided into four stages: inflammatory response, soft callus formation, hard callus formation, and bone remodeling. Osteoclasts play a leading role in hard callus formation and bone remodeling. Alendronate can inhibit osteoclast activity and bone loss in patients with osteoporosis, but it may also inhibit fracture healing. Therefore, whether alendronate can be used after osteoporotic fracture is controversial. In recent years, it has been found that alendronate can not affect the fracture healing, but also reduce the risk of secondary fracture and improve the prognosis of patients. In this article, the mechanism of alendronate and its effect on osteoporotic fracture healing by systemic and local use are reviewed, which can provide a reference for clinical selection of therapeutic drugs. \u0000 \u0000 \u0000Key words: \u0000Osteoporotic fractures; Fracture healing; Alendronate","PeriodicalId":10161,"journal":{"name":"Chinese Journal of Trauma","volume":"36 1","pages":"63-67"},"PeriodicalIF":0.0,"publicationDate":"2020-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47387995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive value of American Society of Anesthesiologists classification on prognosis of elderly patients with hip fracture","authors":"Xiaowei Wang, T. Sun, Jianzheng Zhang, Jian-wen Zhao","doi":"10.3760/CMA.J.ISSN.1001-8050.2020.01.011","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1001-8050.2020.01.011","url":null,"abstract":"Objective \u0000To explore the predictive effect of American Society of Anesthesiologists (ASA) classification on prognosis of elderly patients with hip fracture. \u0000 \u0000 \u0000Methods \u0000A retrospective case-control study was conducted to analyze the clinical data of 814 elderly patients with hip fracture admitted to the 7th Medical Center of the General Hospital of the PLA from January 2012 to December 2015. There were 272 males and 542 females, with the age range of 60-99 years [(80.0±8.0)years]. According to ASA classification, the patients were divided into four groups: 23 cases (2.8%) of ASA grade I, 380 cases (46.7%) of ASA grade II, 389 cases (47.8%) of ASA grade III and 22 cases (2.7%) of ASA grade IV. Data compared among the groups included gender, age, comorbidities, fracture type, anesthesia methods, surgical methods, length of hospital stay, complications, and 30-day and 1-year mortality rates. Multiple Logistic analysis was conducted to seek independent risk factors for 1-year mortality. \u0000 \u0000 \u0000Results \u0000There were no significant difference among the four groups with regards to gender, fracture type, surgical methods (P>0.05 ). With the improvement of ASA classification, the age of patients increased gradually, the length of hospital stay increased, and the rate of nerve block anesthesia increased ( allP<0.01). Incidence of complications of ASA grade IV patients was the highest [59%(13/22)], followed by 31.4%(122/389) of ASA grade Ⅲ patients, 17.6%(67/380) of ASA grade II patients, 4%(1/23) of ASA grade I patients (all P<0.01). The 30-day and 9-0day mortality of ASA grade IV patients were 32% (7/22), 64% (14/22), ASA grade III patients were 4.6% (18/389), 17.0% (66/389), ASA grade II patients were 3.4% (13/380), 12.1% (46/380), and ASA grade I patients were 0 and 4% (1/23), respectively. The differences between these groups were significantly different ( allP<0.01). Univariate analysis showed that male, advanced age, coronary heart disease, pulmonary infections, chronic obstructive pulmonary diseases (COPD), renal insufficiency, ASA classification, anesthesia methods, and length of hospital stay were related to postoperative 1-year death (P<0.05 or 0.01). A total of 127 patients (15.6%) died within 1 year after operation. Multivariate Logistic regression analysis showed age (OR=1.037, 95%CI 1.007-1.068), ASA grade(ASA grade II : OR=1.851, 95%CI 1.238-14.386; ASA grade III : OR=2.092, 95%CI 1.266-16.482; ASA grade IV: OR=15.368, 95%CI 1.626-145. 283), length of hospital stay (OR=1.038, 95%CI 1.015-1.061) were independent risk factors for 1-year mortality. \u0000 \u0000 \u0000Conclusions \u0000The outcome of the elderly hip fracture is poor. The ASA classification is closely related to the incidence of complications, 30-day mortality, and 1-year mortality. Advanced age, ASA grade II, III and IV, hospital length of stay are the independent risk factors for poor prognosis of hip fractures. The ASA classification can be used as a screening tool to intervene for the high-risk ","PeriodicalId":10161,"journal":{"name":"Chinese Journal of Trauma","volume":"36 1","pages":"51-57"},"PeriodicalIF":0.0,"publicationDate":"2020-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41355571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of tranexamic acid combined with temporary clamping of drain in reducing perioperative blood loss of Schatzker V and VI tibial plateau fracture","authors":"Zhimeng Wang, Yao Lu, Jiarui Yang, Qian Wang, T. Ma, Zhong Li, Kun Zhang","doi":"10.3760/CMA.J.ISSN.1001-8050.2020.01.014","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1001-8050.2020.01.014","url":null,"abstract":"Objective \u0000To investigate the safety and effect of tranexamic acid combined with drainage tube clamping to reduce perioperative blood loss of Schatzker V and VI tibial plateau fracture. \u0000 \u0000 \u0000Methods \u0000A prospective case-control study was performed on 87 patients with Schatzker V and VI tibial plateau fracture admitted from March 2018 to January 2019 in Honghui Hospital, including 53 males and 34 females, aged 24 to 69 years [(39.05±2.7)years]. All patients underwent tibial plateau reduction and internal fixation. According to the random number table method, the patients were divided into intravenous group (27 cases), articular cavity group (30 cases) and control group (30 cases). The intravenous group were given a total of 1 g of tranexamic acid intravenously 5-10 minutes before loosening the tourniquet, the joint cavity group were perfused with 1 g of tranexamic acid before closing the incision, and the control group were given the same amount of normal saline. The drainage tube was temporarily clamped for 4 hours in the three groups. Data were recorded and compared among the groups, including the surgical limb side, tourniquet use time, hemoglobin (Hb), D-dimer level, drainage, total blood loss, number of allogeneic blood transfusions, postoperative complications, and presence or absence of deep vein thrombosis (DVT) of the lower extremities at 72 hours after discharge. \u0000 \u0000 \u0000Results \u0000There was no significant difference in baseline data between the three groups (P>0.05). There were no significant differences in the extremity side, tourniquet use time, and number of allogeneic blood transfusions among the three groups (P>0.05). At postoperative 24 hours, the Hb was (112.7±11.8)g/L in the intravenous group, (107.7±16.1) g/L in the articular cavity group, At (100.0±10.4) g/L in the control group. At postoperative 24 hours, the D-dimer vein was (5.5±2.9)mg/L in the intravenous group, (5.9±2.5)mg/L in the joint cavity group, and (7.5±3.6)mg/L in the control group. At postoperative 24 hours, the drainage volume was (62.8±20.5)ml in the intravenous group, (60.2±17.4)ml in the articular cavity group, and (81.2±21.1)ml in the control group. The hidden blood loss was (577.1±212.1)ml in the intravenous group, (634.2±139.8)ml in the articular cavity group, (750.3±124.1)ml in the control group. The total blood loss was (950.1±170.5)ml in the intavenous group, (1 005.4±179.8)ml in the articular cavity group, and (1 148.8±129.1)ml in the control group. The incidence of postoperative wound swelling and exudation was 1 case (4%) in the intravenous group, 0 cases in the articular cavity group, 5 cases (17%) in control group. The above indexes showed significant differences between the three groups (P 0.05). The Hb at 72 hours postoperatively, total drainage, number of allogeneic blood transfusions, lower extremity DVT and incidence of skin ecchymosis had no significant difference among the three groups(P>0.05). No pulmonary embolism occurred after the operation. \u0000","PeriodicalId":10161,"journal":{"name":"Chinese Journal of Trauma","volume":"36 1","pages":"68-74"},"PeriodicalIF":0.0,"publicationDate":"2020-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42107219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Holding a new view of paying equal attention to prevention and treatment of bone trauma in the elderly","authors":"Yingze Zhang","doi":"10.3760/CMA.J.ISSN.1001-8050.2020.01.003","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1001-8050.2020.01.003","url":null,"abstract":"With increase of aging population in China, the aging disease especially bone trauma in the elderly is important problem in clinical practice. However, the treatment of bone trauma in the elderly requires a conceptual change. In this paper, the author proposes a new concept of combining prevention and treatment for bone trauma in the elderly from four aspects including active choice of surgical treatment, fully coordinated preoperative preparation, principle of minimally invasive reduction with strong fixation and postoperative rehabilitation exercise. Meanwhile, some suggestions are provided for elimination of preoperative fear, prevention of falling down as well as prevention and treatment of knee osteoarthritis in the elderly. The synergistic efforts from medical staff, patients' families and the whole society are needed for firmly holding the new view to attain effective prevention and treatment of bone trauma in the elderly. \u0000 \u0000 \u0000Key words: \u0000Aged; Osteoporotic fractures; Preventive medicine; Therapeutics","PeriodicalId":10161,"journal":{"name":"Chinese Journal of Trauma","volume":"36 1","pages":"6-8"},"PeriodicalIF":0.0,"publicationDate":"2020-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43376162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Attach great importance to postoperative use of bisphosphonate following osteoporotic fracture","authors":"Xinli Zhi, Chen Xiao, S. Jiacan","doi":"10.3760/CMA.J.ISSN.1001-8050.2020.01.005","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1001-8050.2020.01.005","url":null,"abstract":"Osteoporotic fracture is a clinical problem resulting in significant morbidity and mortality. The main treatment for osteoporosis is bisphosphonate therapy. Bisphosphonates can inhibit the bone resorption by osteoclasts, inhibit bone alteration, and maintain bone mass. In recent years, basic and clinical studies have not found evidence that the use of bisphosphonates for the inhibition of fracture healing. Therefore, for the patients with confirmed osteoporotic fracture, bisphosphonate should be used to reduce the risk of re-fracture. The authors summarize the related studies in the bisphosphonate intervention for osteoporotic fracture and recommend postoperative use of bisphosphonate for osteoporotic fracture. \u0000 \u0000 \u0000Key words: \u0000Osteoporosis; Osteoporotic fractures; Disphosphonates","PeriodicalId":10161,"journal":{"name":"Chinese Journal of Trauma","volume":"36 1","pages":"14-17"},"PeriodicalIF":0.0,"publicationDate":"2020-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41916709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}