重视骨质疏松性骨折术后使用双磷酸盐

中华创伤杂志 Pub Date : 2020-01-15 DOI:10.3760/CMA.J.ISSN.1001-8050.2020.01.005

Xinli Zhi, Chen Xiao, S. Jiacan

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引用次数: 0

摘要

骨质疏松性骨折是一个发病率和死亡率都很高的临床问题。治疗骨质疏松症的主要方法是双膦酸盐疗法。双膦酸盐能抑制破骨细胞对骨的吸收，抑制骨的改变，维持骨量。近年来，基础和临床研究均未发现双膦酸盐对骨折愈合的抑制作用。因此，对于确诊为骨质疏松性骨折的患者，应使用双膦酸盐来降低再骨折的风险。作者总结了双膦酸盐干预骨质疏松性骨折的相关研究，并推荐术后使用双膦酸盐治疗骨质疏松性骨折。关键词:骨质疏松症;骨质疏松性骨折;Disphosphonates

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Attach great importance to postoperative use of bisphosphonate following osteoporotic fracture

Osteoporotic fracture is a clinical problem resulting in significant morbidity and mortality. The main treatment for osteoporosis is bisphosphonate therapy. Bisphosphonates can inhibit the bone resorption by osteoclasts, inhibit bone alteration, and maintain bone mass. In recent years, basic and clinical studies have not found evidence that the use of bisphosphonates for the inhibition of fracture healing. Therefore, for the patients with confirmed osteoporotic fracture, bisphosphonate should be used to reduce the risk of re-fracture. The authors summarize the related studies in the bisphosphonate intervention for osteoporotic fracture and recommend postoperative use of bisphosphonate for osteoporotic fracture. Key words: Osteoporosis; Osteoporotic fractures; Disphosphonates

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来源期刊

中华创伤杂志

自引率

0.00%

发文量

11327

期刊介绍： Chinese Journal of Trauma (International Standard Serial Publication Number: ISSN 1001-8050, Domestic Uniform Serial Publication Number: CN 50-1098/R) was founded in September 1985, which is the only high-level medical professional academic journal that can comprehensively and systematically reflect the achievements and development trends of China's traumatology medicine, and has a wide academic influence in China's traumatology medicine community. It has a wide range of academic influence in China's trauma medicine. Chinese Journal of Trauma is a source journal of China Science and Technology Paper Statistics, a source journal of China Science Citation Database (CSCD), a core journal of China Comprehensive Medicine and Health Care, a source journal of China Academic Journals Comprehensive Evaluation Database (CAJCED), a full-text journal of China Journal Full-text Database (CJFD), a core academic journal of China Center for Scientific Evaluation (RCCSE), a core academic journal of China Traumatology and Traumatology Center (CTC), a core academic journal of China Traumatology Center (RCCSE). RCCSE) core academic journals; Chinese Biomedical Journal Database (CMCC), Chinese Biomedical Journal Citation Database (CBJCED), China Journal Network (CJN), China Academic Journals (CD-ROM), Chinese Academic Journals Abstracts (Chinese Edition), Chemical Abstracts of the United States (CA), Index Copernicus of Poland (IC), and Japan Institute of Science and Technology Database (JICST), World Health Organization Western Pacific Region Medical Search (WPRIM) and Russian Journal of Abstracts (ΡЖ) included journals.