Medecine tropicale et sante internationale最新文献

{"title":"[The role of histopathology in the diagnosis and management of intracranial meningiomas. Hospital experience in Kinshasa (Democratic Republic of Congo)].","authors":"Elie Nkamba Kapiamba, Olive Kisile Mikuo, Glennie Ntsambi Eba, Jean-Marie Kabongo Mpolesha, Bienvenu Lebwaze Massamba, Raphaël Chirimwami Bulakali","doi":"10.48327/mtsi.v5i4.2025.647","DOIUrl":"10.48327/mtsi.v5i4.2025.647","url":null,"abstract":"<p><strong>Introduction: </strong>Meningiomas are the most common type of intracranial brain tumor and are usually benign. While histopathology is still considered the gold standard for diagnosing and classifying meningiomas, treatment in developing countries heavily relies on computed tomography (CT) and magnetic resonance imaging (MRI). Therefore, it is important to have imaging results that are as accurate as possible. The aim of this study was to determine the contribution of histopathology to the diagnosis of intracranial meningiomas in tertiary healthcare facilities (THFs) in Kinshasa, Democratic Republic of Congo.</p><p><strong>Materials and methods: </strong>We conducted a descriptive, cross-sectional study in THFs with pathology and neurosurgery departments in the city-province of Kinshasa, over a period of ten years. We analyzed 102 patient files of individuals admitted and operated on for a brain tumor.Results. The main complaints were neurological and cephalic deficits and optic nerve damage in 49 (48%) and 23 (22.5%) patients, respectively. The most common diagnostic hypotheses were meningioma (43.1%), brain tumor (27.5%), and expansive intracranial process (13.7%). Eighty-four patients (92.2%) underwent CT scans, and seven (6.9%) underwent MRIs. The most common diagnoses were meningioma in 40 patients (39.2%), brain tumor in 34 patients (33.3%), and glioma in 15 patients (14.7%).Of the 36 patients who underwent histopathological examination, 20 (56%) had meningiomas, and five (14%) had oligodendrogliomas. Of the 20 cases of meningioma diagnosed by histopathology, seven (35%) were fibroblastic meningiomas, and four (20%) were mixed meningiomas. Medical imaging allowed for a meningioma diagnosis in only five cases (25%). Most meningiomas were grade 1 (85%), followed by grade 3 (10%). Conclusion. Despite the importance of histopathology in evaluating and understanding meningioma grade, most of our patients do not undergo this procedure. There is a significant discrepancy between imaging findings and histopathological findings of meningiomas, which requires awareness among various healthcare providers.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12957992/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147367813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[A case of Guillain-Barré syndrome due to infection with <i>Rickettsia conorii</i> in Tunisia].","authors":"Yosr Ben Taher, Rania Ammar, Mabrouk Bahloul, Chokri Ben Hamida","doi":"10.48327/mtsi.v5i4.2025.768","DOIUrl":"10.48327/mtsi.v5i4.2025.768","url":null,"abstract":"<p><strong>Introduction: </strong>Mediterranean spotted fever is an infection caused by <i>Rickettsia conorii</i> that is endemic to the Mediterranean basin. It is mainly transmitted by ticks. The association between this infection and Guillain-Barre syndrome (GBS) is uncommon.</p><p><strong>Observation: </strong>We present the case of a 29-year-old Tunisian patient with no prior medical conditions who presented with flaccid quadriplegia that progressed to respiratory distress. This was accompanied by persistent fever and hepatosplenomegaly. Acute motor axonal GBS was diagnosed through electroneuromyography, and <i>R. conorii</i> infection was diagnosed through serology. Treatment with immunoglobulins and doxycycline led to gradual clinical improvement.</p><p><strong>Conclusion: </strong>This case underscores the importance of considering <i>R. conorii</i> infection in patients with GBS presenting with systemic symptoms, especially in endemic regions like Tunisia.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12948365/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147329043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Loss of consciousness and epileptic episodes in Mali. What is your diagnosis?]","authors":"Mahamane Mariko, Mamoudou Camara, Kimba B Abdoul Nasser, Abdoulaye Mody Camara","doi":"10.48327/mtsi.v5i4.2025.765","DOIUrl":"10.48327/mtsi.v5i4.2025.765","url":null,"abstract":"<p><p>A 15-year-old girl presented to the neuropediatric department with sudden loss of consciousness and a history of vomiting, intermittent headaches, dizziness, visual disturbances, and epileptic seizures. What is your diagnosis?</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12948372/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147329068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Nasal wart lesion: a Moroccan case of atypical cutaneous leishmaniasis].","authors":"Khalil Zimi, Imane Zouaoui, Hanaa Nejjari, Sarra Aoufi","doi":"10.48327/mtsi.v5i4.2025.681","DOIUrl":"10.48327/mtsi.v5i4.2025.681","url":null,"abstract":"<p><strong>Introduction/justification: </strong>Cutaneous leishmaniasis (CL) is an endemic parasitic disease in Morocco. It is of particular concern due to the diversity of species involved and their varied clinical manifestations. <i>Leishmania infantum,</i> which is often associated with visceral leishmaniasis, can also cause localized cutaneous forms of the disease in certain epidemiological contexts. We present a case of atypical nasal CL caused by <i>L. infantum.</i></p><p><strong>Observation: </strong>A 60-year-old female patient residing in Salé with no significant medical history presented with a verrucous inflammatory lesion on the left side of her nose. The lesion appeared six months after she stayed in the city of Taza. Clinical examination and parasitological analysis led to a diagnosis of cutaneous leishmaniasis. PCR-RFLP identified the species as <i>L. infantum.</i> The lesion partially healed after treatment with meglumine antimoniate.</p><p><strong>Discussion/conclusion: </strong>This case reports an atypical presentation of CL in the form of a rare verrucous nasal lesion caused by <i>L. infantum.</i> This species is classically associated with visceral leishmaniasis, but it is increasingly being reported in localized cutaneous manifestations. This case demonstrates the clinical diversity of CL. The delay in diagnosis resulted in only partial healing, which highlights the importance of early recognition of unusual forms. This case also underscores the need to strengthen epidemiological surveillance and raise awareness among healthcare professionals and exposed populations as part of an integrated strategy to combat CL.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12948355/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147329066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Transfusion risk in sub-Saharan Africa: current situation and challenges specific to the Democratic Republic of Congo].","authors":"Lambert Morisho Mulakwa, Archippe Muhandule Birindwa, Chérone Nancy Mbani Mpega Ntigui, Patrick Ntagereka Bisimwa, Sandrine Lydie Oyegue Liabagui","doi":"10.48327/mtsi.v5i4.2025.693","DOIUrl":"10.48327/mtsi.v5i4.2025.693","url":null,"abstract":"<p><strong>Introduction: </strong>Ensuring the safety of blood transfusions remains a significant health challenge in sub-Saharan Africa (SSA), especially in the Democratic Republic of Congo (DRC). Political instability, inadequate infrastructure, and the absence of comprehensive hemovigilance systems exacerbate the risks. This situation exposes blood transfusion recipients to post-transfusion complications, especially infectious ones, that could be avoided. Additionally, sociocultural mistrust of blood donation contributes to the shortage of safe blood products. This narrative review aims to address the current issues related to transfusion safety in SSA, particularly in the DRC.</p><p><strong>Method: </strong>An integrative narrative review was conducted from January to April 2025 using the following English and French keywords: \"transfusion safety,\" \"sub-Saharan Africa,\" \"blood transfusion risks,\" \"post-transfusion surveillance,\" \"transfusion-transmitted infections,\" \"hemovigilance,\" and \"Democratic Republic of the Congo,\" either alone or in combination using Boolean operators. Original articles, systematic reviews, institutional reports, and recommendations from public health organizations published between 2000 and 2025 were included. The selection focused on sources relevant to transfusion safety systems, clinical practices in settings with limited resources, and surveillance models in low-and middle-income countries.</p><p><strong>Results: </strong>The DRC still lacks an operational national hemovigilance system. Transfusion management remains decentralized, fragmented, and insufficiently standardized, which compromises the quality and safety of care.The lack of traceability and incomplete screening sometimes expose recipients to avoidable risks. However, several local initiatives supported by non-governmental organizations (NGOs), academic institutions, or international programs are emerging. Identified levers include developing digital surveillance tools, networking sentinel laboratories, improving access to safe blood in peripheral areas, and creating regional centers for continuing education and applied research in transfusion safety.</p><p><strong>Conclusion: </strong>Ensuring the long-term safety of blood transfusions in the DRC requires a systemic, integrated, multisectoral approach based on contextual innovation, institutional support, and strengthening local research capacities. Political mobilization and strengthening partnerships are essential to establishing an effective hemovigilance system.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12948373/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147328730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[West African tick-borne relapsing fever, a neglected disease of major public health importance in Senegal].","authors":"El Hadji Ibrahima Ndiaye, Georges Diatta, Cheikh Sokhna, Philippe Parola","doi":"10.48327/mtsi.v5i4.2025.573","DOIUrl":"10.48327/mtsi.v5i4.2025.573","url":null,"abstract":"<p><strong>Introduction: </strong>Tick-borne relapsing fever (TBRF) is a zoonotic disease caused by various species of <i>Borrelia</i> that are transmitted to humans worldwide through the bite of soft ticks belonging to the genus <i>Ornithodoros.</i> In Senegal, as in other endemic regions of West Africa, cases of TBRF caused by <i>B. crocidurae</i> and transmitted by <i>Ornithodoros sonrai</i> ticks are underdiagnosed. The disease is not well known among doctors, nurses, or the general population. In some regions, TBRF is the leading cause of vector-borne fever, surpassing malaria.</p><p><strong>Materials and methods: </strong>This narrative and systematic review reports on the entomological, mammalogical, epidemiological, and clinical aspects of TBRF in Senegal. Small wild mammals, the main reservoir hosts of <i>B. crocidurae,</i> have been identified and mapped, along with the known distribution of the tick vectors. Conventional diagnostic methods, such as visualization of spirochetes on thick blood smears and/or blood smears, as well as modern molecular biology methods and antibiotic treatment, are described.</p><p><strong>Conclusion: </strong>The strategy for preventing and controlling TBRF in Senegal involves improving living conditions, filling in burrows, and trapping small mammals in human dwellings. Health authorities in endemic regions need to better disseminate these methods through awareness campaigns.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12957993/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147367767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Use of antiparasitic drugs in the prevention of congenital toxoplasmosis: systematic review and meta-analysis].","authors":"Richard Amagbégnon, Aretas Babatoundé Nounnagnon Tonouhéwa, Magalie Dambrun, Célia Dechavanne, Aurore Ogouyemi-Hounto, Florence Migot-Nabias, Marie-Laure Dardé, Aurélien Mercier, Dorothée Kindé-Gazard","doi":"10.48327/mtsi.v5i4.2025.753","DOIUrl":"10.48327/mtsi.v5i4.2025.753","url":null,"abstract":"<p><strong>Introduction: </strong>In the context of preventing congenital <i>Toxoplasma gondii</i> infection, optimizing the use of antiparasitic molecules, such as spiramycin, pyrimethamine-sulfadiazine combinations, cotrimoxazole, and pyrimethamine-sulfadoxine, during the prenatal period is a significant challenge in limiting maternal-fetal transmission and reducing associated effects.</p><p><strong>Materials and methods: </strong>A systematic review of cohort studies published between 2000 and 2023 was conducted to determine the overall risk of mother-to-fetus transmission in pregnant women with primary <i>Toxoplasma gondii</i> infection, whether they are treated or not. The risk of maternal-fetal transmission in women undergoing treatment corresponds to the treatment failure rate.</p><p><strong>Results: </strong>The average overall risk of maternal-fetal transmission was estimated at 49% (95% CI, 36%-63%) among pregnant women infected during pregnancy who did not receive <i>anti-toxoplasma</i> treatment. This risk was assessed by categorizing the women according to their region of residence or whether their healthcare system had a prenatal care strategy. Among groups of pregnant women treated with spiramycin or pyrimethamine-sulfadiazine, the average overall treatment failure rates were 16% (95% CI, 7%-26%) and 11% (95% CI, 3%-22%), respectively, when the women were stratified according to region of residence or whether the healthcare system had a routine prénatal screening strategy. Congenital infection can cause several disorders, and the frequency of these disorders can be reduced by treating the maternal infection. There is insufficient data for a meta-analysis of treatment regimens such as pyrimethamine-sulfadoxine or sulfamethoxazole-trimethoprim combinations.</p><p><strong>Conclusion: </strong>The failure rate of standard <i>anti-toxoplasma</i> treatments can be reduced by addressing several recognized risk factors early on. Each healthcare system must strengthen the monitoring and evaluation of treatment policies for primary infection per pregnancy in order to implement a more appropriate secondary prevention strategy.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12948362/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147328789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Knowledge, perceptions and attitudes of medical auxiliaries and assistants on telemedicine in Togo].","authors":"Kokou Adambounou, Rarba Baniki Morouma-Tissoga, Akoété Beleave Kouevidjin","doi":"10.48327/mtsi.v5i4.2025.744","DOIUrl":"10.48327/mtsi.v5i4.2025.744","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to evaluate the knowledge, perceptions, and attitudes of medical auxiliaries and assistants regarding telemedicine in Togo.</p><p><strong>Methodology: </strong>This descriptive cross-sectional study was conducted from March 27 to June 26, 2021, and included medical auxiliaries and assistants working in Togo. Participants completed the questionnaires electronically via Google Forms or in printed format.</p><p><strong>Results: </strong>Of the 315 medical auxiliaries and assistants surveyed, 76.2% were auxiliaries (including 81.7% nurses and midwives), and 23.8% were assistants. Seventy-six point eight percent had heard of telemedicine at least once. They were familiar with teleconsultation (53%), telemonitoring (18.1%), and telehealth assistance (15.2%). The main barriers to developing telemedicine that were cited were economic difficulties (64.8%) and organizational barriers (54.3%). They knew that patient consent is required for telemedicine procedures in 48.6% of cases. Eighty-two percent of them considered telemedicine useful for everyday medical practice, and nearly all (90.5%) wanted training in telemedicine. They practiced telemonitoring (27.4%) and telehealth assistance (24.2%). Seventy-five percent used WhatsApp to prescribe remotely, and 49.8% used it to monitor patients remotely.</p><p><strong>Conclusion: </strong>Despite their limited knowledge, medical auxiliaries and assistants in Togo had a positive perception of telemedicine; however, they did not always adopt good attitudes.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12948359/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147329002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Risk of emergence of mosquito-borne arboviral diseases in Morocco: literature review].","authors":"Samya Jdiaa, Hanan Hazyoun, Moulay Anass Louah, Oumnia Himmi","doi":"10.48327/mtsi.v5i4.2025.671","DOIUrl":"10.48327/mtsi.v5i4.2025.671","url":null,"abstract":"<p><strong>Introduction: </strong>The emergence of arboviruses, or viruses transmitted by arthropods, is now one of the world's biggest health problems. The globalization of trade and travel, coupled with uncontrolled urbanization in many cities, has created ideal conditions for mosquito vectors to establish themselves and introduced opportunities for arboviruses to spread.</p><p><strong>Method: </strong>In this review, we summarize historical and recent data on arthropod-borne diseases and their vectors in Morocco.</p><p><strong>Results: </strong>According to seroepidemiological studies there is a risk of emergence and epidemics in Morocco due to the recent circulation of West Nile virus among equids and birds as well as in populations of <i>Culex</i> mosquitoes. The introduction of new invasive mosquito species, such as <i>Aedes albopictus</i> (a vector of dengue, Zika, and chikungunya), further exacerbates this risk. About fifteen mosquito species as vectors for transmitting pathogens to humans and animals have been reported in Morocco.</p><p><strong>Conclusion: </strong>In order to understand arbovirus epidemics and virus transmission, it is necessary to study mosquito vectors first, in order to gain a comprehensive awareness of the current risk facing our country and to be well prepared for future threats.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12957995/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147367790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Use of genetic material extracted from rapid malaria diagnostic tests using PCR during the Grand Magal of Touba in Senegal].","authors":"Coumba Diouf, Ihssane Ouaddane, Georges Diatta, Mamadou Lamine Bara Goumbala, Abdourahmane Sow, Déguène Fam, Mbayang Faye, Philippe Gautret, Cheikh Sokhna","doi":"10.48327/mtsi.v5i4.2025.733","DOIUrl":"10.48327/mtsi.v5i4.2025.733","url":null,"abstract":"<p><strong>Introduction: </strong>The Grand Magal of Touba (GMT), a religious event, attracts between four and five million pilgrims and poses a significant risk of infectious disease transmission, including malaria. Rapid diagnostic tests (RDTs) are commonly used during the event. This study aimed to validate the use of genetic material extracted from RDTs for retrospective diagnostic testing by PCR.</p><p><strong>Methods: </strong>Two types of RDTs were collected from eight health facilities in the Mbacke department in 2022 and 2023 during the GMT: Bioline™ Malaria Ag P.f/Pan (Abbott, USA) and ParaHIT^® (Arkray, India) which detects <i>Plasmodium falciparum.</i> Real-time PCR (qPCR) was performed after opening the RDTs and extracting DNA/RNA to confirm the visual reading of the antigen tests. The performance of the collected RDTs was calculated relative to the PCR results, which were considered the reference standard.</p><p><strong>Results: </strong>A total of 2,381 RDTs were collected, 213 of which (8.9%) were positive according to the test readings (135 according to Bioline™ tests, and 78 according to ParaHIT). According to qPCR, 194 samples (8.1%) were positive for <i>P. falciparum.</i> There were false positives in 39 (2.5%) Bioline™ Jests and 57 (7.2%) ParaHIT tests, as well as false negatives in 68 (4.3%) Bioline™ tests and 9 (1.1%) ParaHIT^® tests. The Bioline™ and ParaHIT^® tests were 97.3% and 92.5% specific, respectively. Their positive predictive values were 71.1% and 26.9%, respectively, and their negative predictive values were 95.3% and 98.7%, respectively.</p><p><strong>Conclusion: </strong>Genetic material extracted from RDT cassettes can be used for subsequent PCR diagnosis with increased specificity and sensitivity.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12948358/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147328843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}