Medecine tropicale et sante internationale最新文献

{"title":"[Multiple tuberculous cold abscesses associated with Pott's disease in an immunocompetent patient with cervical localization in Burkina Faso].","authors":"Cheick Rachid Bargo, Wendbénédo Habacuc Sare, Mohamed Karfalla Kaba, Modibo Abdoulaye Nana","doi":"10.48327/mtsi.v5i1.2025.600","DOIUrl":"https://doi.org/10.48327/mtsi.v5i1.2025.600","url":null,"abstract":"<p><strong>Introduction: </strong>Cervical Pott's disease is a very rare localization of bone tuberculosis. Its association with cercico-thoracic cold abscesses is also exceptional.</p><p><strong>Observation: </strong>A 36-year-old black African patient of Burkinabè origin, with a history of tuberculosis infection (his mother had pulmonary tuberculosis) and no other pathological history, presented with chronic inflammatory cervicalgia that had been developing for six months in a non-febrile context of altered general condition. Examination showed a left latero-cervical swelling associated with a left basithoracic swelling, both fluctuant. Pleuropulmonary and neurological examinations were normal. HIV serology and tuberculin skin test were negative. Cervico-thoracic computed tomography revealed multiple abscesses. The abscesses were incised and drained. Analysis of the specimen showed the presence of acid-fast bacilli by direct examination and <i>Mycobacterium tuberculosis</i> by Xpert test, with sensitivity to rifampicine. The diagnosis was multiple tuberculous cold abscesses associated with cervical Pott's sore. The patient was started on standard analgesics and antituberculosis drugs for 12 months. The course was favorable, with a follow-up of one year after treatment.</p><p><strong>Conclusion: </strong>Cold cervical abscess complicating Pott's disease is exceptional. Imaging and the geneXpert assay are now rapid and effective diagnostic tools for tuberculosis. This particular form should always be suspected in endemic areas.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001987/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144034823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Still's disease in sub-Saharan Africa through ten observations from the internal medicine department of Libreville University Hospital (Gabon)].","authors":"Josaphat Iba Ba, Annick Mfoumou, Ingrid Nseng-Nseng Ondo, Arthur Kanganga Ekomy, Léonie Esther Ledaga Lentombo, Marielle Igala, Ulrich Davy Kombila, Jean Bruno Boguikouma","doi":"10.48327/mtsi.v5i1.2025.629","DOIUrl":"https://doi.org/10.48327/mtsi.v5i1.2025.629","url":null,"abstract":"<p><strong>Introduction: </strong>Introduction. Still's Disease (SD) is a rare systemic inflammatory disorder that is most common in children. In the adult form, it can be primary or the resurgence of an infantile form. We report 10 observations of Still's disease in the Gabonese population, with the aim of confirming its existence in this country an studying its specific features.</p><p><strong>Material and methods: </strong>This was a retrospective, descriptive and analytical study carried out in the Internal Medicine Department of the CHU of Libreville from 1.12.2003 to 31.12.2021, using the records of patients hospitalized in this department and/or followed up on an outpatient basis. The selected patients fulfilled the Yamaguchi and Fautrel criteria. Epidemiologic, socioeconomic, clinical, biological, morphologic, immunologic, therapeutic, evolutionary and seasonal data were detailed.</p><p><strong>Results: </strong>Ten patients (4 men and 6 women), mostly students with a mean age of 22 years, were included. The time to diagnosis of SD was 31.3 months, with fever in 100% of cases, joint and skin involvement in 80%, and ENT involvement in 70%. An inflammatory syndrome, predominantly neutrophilic hyperleukocytosis, hepatic signs, and hyperferritinemia coexisted with an immunologic work-up that was always negative. Corticosteroid therapy (n=10) combined with per os methotrexate from the beginning (n=1) or in cases of corticoresistance (n=4) was the rule. One patient died and one was lost to follow-up.</p><p><strong>Discussion and conclusion: </strong>The clinical and biological presentation of SD is comparable to that of the Caucasian population. However, our study confirms in the low incidence of liver, lymph node and heart damage, which needs to be confirmed by other studies in a larger cohort. The high cost of this disease, which is a diagnosis of exclusion, may partly explain the difficulties in diagnosing SD.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001992/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[<i>Brucella</i> spondylodiscitis and factors associated with prognosis: a case series from Sétif, Algeria].","authors":"Wahiba Guenifi, Houda Boukhrissa, Abdelkader Gasmi, Abdelmadjid Lacheheb","doi":"10.48327/mtsi.v5i1.2025.563","DOIUrl":"https://doi.org/10.48327/mtsi.v5i1.2025.563","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>Spondylodiscitis is a serious and suggestive complication of brucellosis. Few studies have been devoted to it in Algeria, although the infection remains a public health problem. The aim of this study was to report the epidemiological and clinical aspects of brucellosis spondylodiscitis and to identify the neurological complications.</p><p><strong>Material and methods: </strong>This is a descriptive analysis of a cohort of adult patients with <i>Brucella</i> spondylodiscitis, based on data collected from patient records recruited between January 2016 and December 2022.</p><p><strong>Results: </strong>Thirteen females and 24 males with a mean age of 48 ± 15 years [21 to 71 years] were included in the study. Diagnosis was made on average 120 days ± 100 [30-360] after the onset of clinical symptoms. Commonly reported symptoms were: back pain (100%), fever (46%), sweating (70%), asthenia (84%), chills (22%), and weight loss (27%). Neurological complications were numerous and sometimes varied in the same patient: one case of paraplegia, three cases of paraparesis, six cases of sensory disturbances, and one case of sphincter disorders. Involvement of the lumbar spine was predominant, observed in 22 patients, including 15 at the L4-L5 level.In addition to discovertebral lesions, imaging revealed 27 cases of epiduritis, 13 cases of spinal cord compression, 25 cases of radicular compression, and pre- or para-vertebral and psoas abscesses.Two treatment regimens were used: doxycycline-cotrimoxazole-gentamycin (22 cases) and doxycycline-rifampicin-gentamycin (15 cases). At the end of the one-year post-therapeutic follow-up, we observed one relapse, sequelae of paraparesis, and sequelae of spinal pain in 12 patients.</p><p><strong>Discussion and conclusion: </strong>This study has allowed us to observe prognostic elements. Early spinal imaging is essential to combat the excessive delay in diagnosis in our patients. There is no clear consensus in the scientific literature regarding neurological complications, such as epiduritis, and optimal treatment. The results of our study may contribute to the development of more personalized management algorithms.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001995/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[<i>Tropical medicine and international health: MTSI</i> clarifies its editorial line].","authors":"Jean-Philippe Chippaux, Jean-Paul Boutin, Michel Develoux, Alain Epelboin, Pierre Gazin, François Moutou, Jean-François Pays, Eric Pichard Sfmtsi","doi":"10.48327/mtsi.v4i4.2024.618","DOIUrl":"10.48327/mtsi.v4i4.2024.618","url":null,"abstract":"<p><p>Tropical medicine, initially associated with colonial medicine and exotic pathology, focused on infectious diseases of warm regions and on environmental and socioeconomic imbalances. Global upheavals such as globalization, urbanization and climate change have broadened the scope of diseases, with the emergence of tropical pathologies in temperate regions and an increase in non-communicable diseases (traumatic, metabolic, psychiatric, etc.) in southern countries.<i>Médecine Tropicale et Santé Internationale (MTSI)</i> accompanies this paradigm shift by integrating noncommunicable diseases and contextualizing the local conditions in which pathologies occur, are diagnosed and treated. It favors analyses based on local specificities, including cultural, socioeconomic and environmental aspects, as well as health system constraints.<i>MTSI</i> therefore insists on contextualization in submitted articles, especially for original studies and clinical cases, emphasizing the impact of local conditions, diagnostic and therapeutic barriers, and the consideration of traditional medicines. It invites authors to demonstrate the relevance and novelty of their observations, while respecting the formal recommendations for publication.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"4 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11892381/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Entomological investigation during the chikungunya epidemic in Chad in 2020].","authors":"Tchonfienet Moundai, Mahamat Alio Hamit, Israël Demba Kodindo, Élise Kalnoné Yangalbe, Hinzoumbé Clément Kerah, Tidjani Abdelsalam, Sévilor Kekeunou","doi":"10.48327/mtsi.v4i4.2024.619","DOIUrl":"10.48327/mtsi.v4i4.2024.619","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this study was to identify chikungunya vectors and study their bioecology in order to contribute to the response to the 2020 epidemic in the cities of Abéché and Biltine in eastern Chad.</p><p><strong>Materials and methods: </strong>Immature stages of <i>Aedes</i> mosquitoes were collected and epidemic risk indices (Container index, House index and Breteau index) were calculated and compared using the Chi-square test. The collected larvae and nymphs were reared, and the resulting adults were morphologically identified using a dichotomous key. Residual endophilic fauna was sampled by morning insecticide spraying in chambers. Only female mosquitoes were collected.</p><p><strong>Results: </strong>A total of 2,039 mosquito specimens belonging to three genera were collected: 470 (23%) were identified as <i>Aedes aegypti,</i> 731 <i>Anopheles</i> spp (36%), and 838 Culex spp (41%). Flowerpots were the most common breeding sites (69%), followed by jars/water barrels (17%) <i>and</i> abandoned tires or containers (14%). The risk indices were all well above the epidemic thresholds defined by the WHO. Between the two cities, only the house index showed a significant difference (p=0.004): it was higher in Abéché than in Biltine.</p><p><strong>Conclusion: </strong>The study identified <i>A. aegypti</i> as a likely vector of chikungunya in both cities. It is important to understand its biting and resting behavior, as well as its sensitivity to different classes of insecticides, in order to organize effective vector control.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"4 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11892385/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Hepatocellular carcinoma (HCC)].","authors":"Stanislas Pol","doi":"10.48327/mtsi.v4i4.2024.614","DOIUrl":"10.48327/mtsi.v4i4.2024.614","url":null,"abstract":"<p><p>Primary liver cancers are tumors that develop from different liver cells. Hepatocellular carcinoma (HCC), which develops from hepatocytes, accounts for approximately 75-85% of primary liver cancers.HCC is the 6^th leading cause of cancer worldwide and the 3^rd leading cause of cancer-related death. Its incidence is low in northern Europe, but high in sub-Saharan Africa and the Far East, where both hepatotropic viruses and exposure to mycotoxins are. It complicates cirrhosis in over 90% of cases and is predominantly male.The prevalence of HCC is increasing due to improved diagnostic techniques and criteria, but also to the persistence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections in adults. A worldwide increase in the incidence of steatopathy makes it the leading cause of liver disease worldwide, associated with alcohol abuse and/or steatohepatitis associated with metabolic dysfunction (MASH), including type 2 diabetes.Chronic hepatotropic viral infections, cirrhosis and chemical carcinogens combine to produce an annual incidence of 2-5% of hepatocellular carcinoma arising from cirrhosis. This justifies biannual surveillance of known cirrhosis, without which late diagnosis limits therapeutic options.Major advances have been made in curative treatment (liver transplantation, surgery, radiodestruction) and palliative treatment (chemo- or radioembolization, sorafenib chemotherapy or immunotherapy), depending on how early HCC is diagnosed (size, number of hepatic or extrahepatic lesions) and the severity of underlying liver disease and associated comorbidities.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"4 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11892391/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Exposure to cassava, corn and soybean dust and respiratory health among artisanal millers in Lubumbashi (Democratic Republic of the Congo)].","authors":"Léon Kabamba Ngombe, Nlandu Roger Ngatu, Kazadi Sha Ngombe, Stanislas Wembonyama Okitotsho, Michel Nzaji Kabamba, Jean-Baptiste Kakoma Sakatolo, Oscar Luboya Numbi","doi":"10.48327/mtsi.v4i4.2024.610","DOIUrl":"10.48327/mtsi.v4i4.2024.610","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this study was to determine the prevalence of respiratory symptoms, their determinants, and the state of respiratory function in millers exposed to cassava, maize, and soybean dust in Lubumbashi, Democratic Republic of Congo (DRC), compared with a group of unexposed workers.</p><p><strong>Methods: </strong>A descriptive and analytical cross-sectional study was conducted in 2015 on 288 millers and 118 agents (n = 406) from a security agency (control group) in Lubumbashi, DRC. Participants were examined at their place of work. Respiratory health information was collected using a standardized questionnaire. Spirometry was performed on each participant.</p><p><strong>Results: </strong>Mean age was 27.6 ± 9 years in millers and 28.5 ± 7 years in controls. Daily working hours were 12.1±1.7 hours for millers and 14.4±6.2 hours for controls. No significant differences were found when comparing the two groups. However, the prevalence of respiratory symptoms was higher in the millers than in the controls, especially wheezing (1.9 times higher), dyspnea (2.1 times higher), breathlessness at rest (6 times higher), breathlessness on exertion (6.4 times higher), chronic bronchitis (6.2 times higher), cough (5.3 times higher) and morning sputum (5.1 times higher). Thus, an association was found between the milling occupation and all respiratory symptoms. Spirometric data showed that forced expiratory volume in one second (FEV1), peak expiratory flow (PEF) (p<0.05) and Tiffeneau ratio (FEV1/FVC) (p<0.001) were significantly reduced in millers compared to controls.</p><p><strong>Conclusions: </strong>This study showed a high prevalence of respiratory symptoms with impaired lung function among millers in Lubumbashi, suggesting the need for preventive measures to reduce exposure in mills.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"4 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11892386/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Evaluation of snakebite management cost at Saint Jean de Dieu Hospital in Tanguiéta, Benin].","authors":"Naryanan Tourita, Noé Sodjinou, Seidou Alassane Ouorou, Éric Ganhouingnon, Achille Massougbodji, Jean-Philippe Chippaux, Sébastien Larréché","doi":"10.48327/mtsi.v4i4.2024.522","DOIUrl":"10.48327/mtsi.v4i4.2024.522","url":null,"abstract":"<p><strong>Introduction: </strong>Snakebite envenomations are a real public health problem in rural areas of sub-Saharan Africa, especially as the cost of management is often beyond the reach of the victims. The aim of our study was to evaluate the costs of treating snakebite envenomations at the Saint Jean de Dieu hospital in Tanguiéta, northern Benin, in a savannah area.</p><p><strong>Methods: </strong>This was a descriptive cross-sectional study conducted over a three-month period from May 25 to August 25, 2023. Snakebite patients were followed from admission to hospital discharge. All care-related expenses incurred by patients and/or their families were accounted for on a daily basis.</p><p><strong>Results: </strong>Fifty-seven patients were included. The median age (interquartile range) of the patients was 27 years (16-40), and the sex ratio was 1.6 (35 males and 22 females). In 81% of cases, the bites were associated with agricultural activities. Approximately 72% of the patients had sought traditional care before coming to the hospital. The median time from bite to admission was 7 hours (2-52) and the median hospital stay was 4 days (2-5). The median cost of care was €168 (154-242). It varied according to the severity of the bite: €31 for a dry bite (26-47); €179 for external bleeding (154-286). The only antivenom used was Inoserp™ PAN-AFRICA (Inosan Biopharma). Its average cost was €128 and was the main expense.</p><p><strong>Conclusion: </strong>The cost of treating snakebite is high and dominated by the cost of antivenom. These economic constraints reinforce the vicious circle of poverty in an already vulnerable population. It is therefore important to find a financing mechanism for this treatment in the most exposed areas.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"4 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11895845/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Dengue fever vaccination Recommendations from the Société Francophone de Médecine Tropicale et de Santé Internationale for Metropolitan France and Overseas Territories].","authors":"Yves Buisson, Éric Pichard","doi":"10.48327/mtsi.v4i4.2024.603","DOIUrl":"10.48327/mtsi.v4i4.2024.603","url":null,"abstract":"<p><p>Dengue fever is spreading rapidly around the world, affecting nearly half the world's population. Causes include urbanization, human mobility, climate change and the spread of mosquito vectors such as <i>Aedes albopictus.</i> In 2023 and 2024, there was a marked increase in cases and deaths worldwide. In mainland France, the increase in imported cases has generated local transmissions.Dengue fever is asymptomatic in over 50% of cases, but can progress to severe forms with potentially fatal complications in 1-5% of symptomatic cases. There are four serotypes of the virus, and re-infection with another serotype increases the risk of severe disease.Two dengue vaccines are currently available: Dengvaxia^® and Qdenga^® (TAK-003). Dengvaxia^® is reserved for people already infected with dengue fever, but production was discontinued in 2024 due to low demand. Qdenga^® is recommended for children aged 6-16 years in high transmission areas. The Société francophone de Médecine tropicale et Santé internationale (SFMTSI) proposes extending vaccination to at-risk adults in endemic overseas territories and to travelers. A communication campaign is proposed to inform the public about the benefits of vaccination while anticipating the risks of anti-vaccination misinformation.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"4 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11892382/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Thyrotoxic hypokalemic periodic paralysis in a black African man in Abidjan (Côte d'Ivoire)].","authors":"Claude Valéry Cédric Aka Kadjo, Ségla Achi Cédric Agbopanzo, Fiacre Delors Offoumou, Arlette Désirée Aka","doi":"10.48327/mtsi.v4i4.2024.543","DOIUrl":"10.48327/mtsi.v4i4.2024.543","url":null,"abstract":"<p><strong>Introduction: </strong>Thyrotoxic hypokalemic periodic paralysis (THPP) is a sporadic form of hypokalemic periodic paralysis (HPP). It is a diagnostic and therapeutic emergency rarely described in the black population. We report a case in a black subject from Côte d'Ivoire.</p><p><strong>Clinical case: </strong>Mr. NK, 37 years old, was admitted to hospital with rapidly progressive motor deficit in all four limbs. The patient had hyperthyroidism, which was treated with neomercazole. His medical history revealed an initial episode that resolved within 30 minutes, followed by a more severe recurrence 4 months later, associated with discontinuation of treatment. Clinical examination revealed flaccid tetraparesis mainly affecting the lower limbs. Biological tests showed hypokalemia of 2.6 mEq/L, ultrasensitive TSH was low (less than 0.005 µL/mL) with T3 and T4 elevations of 24.42 µL/mL and 79.68 µL/mL respectively. We have retained the diagnosis of THPP. The clinical course was satisfactory after correction of the kalemia and readjustment of the hyperthyroidism treatment.</p><p><strong>Discussion: </strong>THPP is common in young Asians and rare in black Africans. The duration of paralysis varies from 1 to 72 hours, with an average of almost 24 hours. Respiratory paralysis, which is potentially serious, is rare. However, discontinuation of treatment in patients already on the drug may predispose to paralysis.</p><p><strong>Conclusion: </strong>The favorable evolution of paralysis after correction of kalemia was confirmed. Our observation highlights the importance of maintaining good thyroid function in patients monitored for hyperthyroidism.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"4 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11892388/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}