{"title":"[Factors associated with acceptance of COVID-19 vaccination in the Kokolo health zone in Kinshasa, Democratic Republic of Congo (DRC)].","authors":"Levis Amisi Kengea, Winnie Masamba Bikoki, Jean-Claude Nsinga Bungiena, Jean-Jacques Kape Kalume","doi":"10.48327/mtsi.v5i4.2025.704","DOIUrl":"10.48327/mtsi.v5i4.2025.704","url":null,"abstract":"<p><strong>Context: </strong>Vaccination is a key preventive strategy in the response to the SARS-CoV-2 pandemic. However, ensuring vaccination adherence remains challenging, particularly in the Kokolo health zone (HZ) in Kinshasa, Democratic Republic of the Congo (DRC), where vaccination coverage remains below 40%. This study aims to identify the factors influencing acceptance of the vaccine among heads of households or their spouses.</p><p><strong>Methodology: </strong>From January 2021 to December 2024, a cross-sectional analytical study was conducted among 399 heads of households (or spouses) selected by three-stage probability sampling. Data were collected through interviews using a structured questionnaire on the <i>KoboCollect</i> application and analyzed using Epi Info 7.2.6.0.</p><p><strong>Results: </strong>Overall, the HZ population reported having heard of both the COVID-19 and its vaccination. Among those surveyed, 79.9% (319 out of 399) considered the vaccine to be effective. The main reasons for not accepting vaccination were never having seen a death or reported case of the disease in the HZ. In a multivariate analysis, acceptance of the vaccine was associated with military service and knowledge of the disease and existing vaccines.</p><p><strong>Conclusion: </strong>When developing strategies to promote Covid-19 vaccination acceptance, knowledge about the disease and existing vaccination, the involvement of political and administrative authorities, military authorities, and community leaders, awareness-raising, and the organization of nearby vaccination sites must be taken into account. Media is the main channel for information and awareness-raising in this HZ.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12948361/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147329032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Josaphat Iba Ba, Annick Mfoumou, Arthur Kanganga Ekomy, Aurélie Baderhwa, Armel Tchibenet Rapontchombo, Michel Arnaud Saphou Damon, Léonie Esther Ledaga Lentombo, Marielle Igala, Jean Bruno Boguikouma
{"title":"[Polyarteritis nodosa: an etiology of myelitis that should not be ignored in subsaharansub-Saharan Africa].","authors":"Josaphat Iba Ba, Annick Mfoumou, Arthur Kanganga Ekomy, Aurélie Baderhwa, Armel Tchibenet Rapontchombo, Michel Arnaud Saphou Damon, Léonie Esther Ledaga Lentombo, Marielle Igala, Jean Bruno Boguikouma","doi":"10.48327/mtsi.v5i4.2025.789","DOIUrl":"10.48327/mtsi.v5i4.2025.789","url":null,"abstract":"<p><strong>Introduction: </strong>Polyarteritis nodosa (PAN) is a systemic necrotizing segmental vasculitis that affects medium-and small-caliber arteries. It is characterized by infiltration of the different layers of the arterial wall (adventitia, media, and intima) by neutrophils, lymphocytes, and eosinophils, resulting in a variety of clinical signs. This infiltration is responsible for reducing arterial caliber, which can range from minimal to severe and cause neurological and digestive manifestations. These manifestations are complicated by a deterioration in the patient's general condition, leading to diagnostic uncertainty in sub-Saharan Africa, where certain infectious diseases (e.g., HIV/AIDS, tuberculosis, and viral hepatitis) are endemic. We present two cases of PAN with initial peripheral neurological involvement (paraplegia and quadriplegia) secondary to transverse myelitis in patients with a history of fetal loss. Through these two case studies, we aim to clarify the characteristics of this rarely described association between PAN and antiphospholipid antibodies.</p><p><strong>Case reports: </strong>The patients, aged 25 and 45, presented with chronic migraines, miscarriages, and a major peripheral neurological deficit that occurred during the dry season (the low-temperature season in Gabon). Magnetic resonance imaging revealed transverse myelitis. An exhaustive autoimmune assessment yielded only a positive result for circulating lupus anticoagulant.</p><p><strong>Discussion: </strong>Although we diagnosed polyarteritis nodosa in these two patients, the role of the lupus anticoagulants remains debatable. These antiphospholipid antibodies are likely to create the conditions for vasculitis due to its persistence in the serum even in the absence of disease activity.</p><p><strong>Conclusion: </strong>The combination of corticosteroid therapy, immunosuppressants, and intensive physical therapy resulted in satisfactory neurological recovery at six and seven months.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12948370/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147329124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Clinical aspects of dengue fever in the Savanna region of Togo in 2023].","authors":"Lidaw Déassoua Bawe, Awèréou Kotosso, Komivi Atsu Kpegba, Mawaba Hilim, Dondah Kozon, Bawoubadi Abaltou, Akouda Akessiwe Patassi, Majesté Ihou Watéba","doi":"10.48327/mtsi.v5i4.2025.788","DOIUrl":"10.48327/mtsi.v5i4.2025.788","url":null,"abstract":"<p><strong>Introduction: </strong>In 2023, the Savanes region of Togo experienced the country's first major dengue epidemic. This study aims to describe the epidemiological, clinical and evolutionary characteristics of confirmed dengue cases during this epidemic.Patients and methods. This retrospective study examined confirmed dengue cases in the Savanes health region from 15 September 2023 to 29 February 2024.Results. During the epidemic, 57 suspected cases of dengue were reported, of which 27 were confirmed. The average patient age was 32 years (range 10-65 years). The main clinical signs were a pain syndrome (n = 19), fever (n = 19), asthenia (n = 17), anorexia (n = 12) and vomiting (n = 11). The distribution of dengue clinical forms included seven cases of classic dengue without warning signs, 15 cases of dengue with warning signs, and five cases of severe dengue. Haematological parameters showed an increase in white blood cell count, particularly in severe dengue cases. Biochemically, renal and hepatic parameters increased in cases of dengue with warning signs and severe dengue. Two deaths from severe dengue were recorded, representing a case fatality rate of just over 7%.</p><p><strong>Conclusion: </strong>This study reports the first major dengue epidemic in northern Togo. A significant proportion of cases were found to be intermediate (warning signs) or severe.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12957991/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147367779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Extradural spinal tumor in a child at Constantine University Hospital (Algeria): what is your diagnosis?]","authors":"Mohamdi Nabil, Badreddine Allouache","doi":"10.48327/mtsi.v5i4.2025.710","DOIUrl":"10.48327/mtsi.v5i4.2025.710","url":null,"abstract":"<p><p>A eight-year-ol d child from the Constantine region with no significant medical history was admitted due to progressive weakness in the lower limbs over a period of approximately 20 days, accompanied by difficulty walking.What is your diagnosis?</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12948367/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147329050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wendlassida Martin Nacanabo, T André Arthur Seghda, Anna Tall/Thiam, Yannick Laurent Tchenadoyo Bayala, André K Samadoulougou
{"title":"[Tuberculous polyseritis, a little-known cause of portal vein thrombosis: a case report from Burkina Faso].","authors":"Wendlassida Martin Nacanabo, T André Arthur Seghda, Anna Tall/Thiam, Yannick Laurent Tchenadoyo Bayala, André K Samadoulougou","doi":"10.48327/mtsi.v5i4.2025.648","DOIUrl":"10.48327/mtsi.v5i4.2025.648","url":null,"abstract":"<p><strong>Introduction: </strong>Due to its rarity and severity, tuberculous polyseritis is a diagnostic challenge that can lead to serious complications. Portal vein thrombosis is an uncommon complication that is often overlooked. This case report illustrates this association in an immunocompetent patient.</p><p><strong>Observation: </strong>A 31-year-old male gold miner with a history of tuberculosis infection was admitted with dyspnea, chest pain, a productive cough, and signs of tuberculosis impregnation that had developed over the course of two months. Physical examination revealed massive left pleurisy, moderate ascites, and pericardial effusion in the pre-tamponade stage. An abdominal ultrasound revealed partial thrombosis of the portal vein. Laboratory tests showed inflammatory anemia, leukopenia, and exudative effusions. <i>Mycobacterium tuberculosis</i> DNA was detected in pleural and peritoneal samples by GeneXpert. A diagnosis of tuberculous polyseritis complicated by portal vein thrombosis was made. The patient received four-drug antituberculosis therapy, as well as pleural and pericardial drainage and acetylsalicylic acid to treat his portal vein thrombosis. The outcome was favorable, with clinical resolution occurring in two months and full recovery occurring in six months.</p><p><strong>Conclusion: </strong>This case highlights the importance of considering tuberculosis as a possible cause of venous thrombosis, even in immunocompetent individuals. Early diagnosis and appropriate management improve the prognosis.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12948363/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147328827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chaimae Moujahid, Soufiane Yassara, Jack E Turman, Loubna Amahdar
{"title":"[Family size control in Morocco: a qualitative exploratory study among rural women].","authors":"Chaimae Moujahid, Soufiane Yassara, Jack E Turman, Loubna Amahdar","doi":"10.48327/mtsi.v5i4.2025.667","DOIUrl":"10.48327/mtsi.v5i4.2025.667","url":null,"abstract":"<p><strong>Objective: </strong>Although women play a central role in family planning, their ability to control their fertility is often influenced by social and relational factors. This study explores the knowledge, attitudes and practices of married women of childbearing age living in rural areas of Morocco regarding family planning and the contraceptive methods currently available.</p><p><strong>Method: </strong>In-depth face-to-face interviews were conducted with 49 married Moroccan women in a rural maternity ward during their postpartum period. Using open-ended questions, we examined their contraceptive practices, decision-making autonomy and the social influences determining their reproductive choices.</p><p><strong>Results: </strong>Most participants reported using oral contraceptives, although many had experienced at least one unintended pregnancy due to contraceptive misuse. The women expressed a preference for smaller families in order to ensure financial stability and a better quality of life. However, they often encountered resistance from their husbands and extended families when attempting to use contraception or limit their family size. There were widespread misconceptions about intrauterine devices (IUDs), with many women requiring their spouse's consent due to concerns about sexual health.</p><p><strong>Conclusion: </strong>Our findings highlight the important role of social and relational factors in women's reproductive choices. Addressing misconceptions and improving access to reproductive health education is essential. Involving husbands in counselling sessions can strengthen family planning efforts and support women's autonomy in fertility-related decisions.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12948356/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147329012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hadissa Tapsoba, Jocelyne Valérie Garé, Aissata Sané Congo, Lamoussa Robert Zoma, Ernest Robert Toé
{"title":"[KAP' (Knowledge Attitude Practices) survey of the population and health professionals regarding oral health and noma in 2012 in the Sahel region, Burkina Faso].","authors":"Hadissa Tapsoba, Jocelyne Valérie Garé, Aissata Sané Congo, Lamoussa Robert Zoma, Ernest Robert Toé","doi":"10.48327/mtsi.v5i4.2025.640","DOIUrl":"10.48327/mtsi.v5i4.2025.640","url":null,"abstract":"<p><strong>Introduction: </strong>Noma is a significant public health concern in the Sahel region of Burkina Faso. To combat this issue, stakeholders have come together to develop a project based on the actual knowledge of local populations and medical professionals about the disease.</p><p><strong>Purpose of the study: </strong>This descriptive study examines knowledge, attitudes, and practices related to noma and oral health in the Sahel region in 2012.</p><p><strong>Results: </strong>Although the population is unfamiliar with the term \"noma\", they generally know the symptoms. However, knowledge of the causes of poor oral health is more confused. While the population is aware of the need for dental hygiene and the possible role of diet, more awareness-raising efforts are needed. There is a gap in the health system's capacity. Health workers are insufficiently trained. Traditional practitioners and the media remain uninvolved in the issue, despite their potential to play a key role.</p><p><strong>Conclusion: </strong>This study impacted the implementation and development of the noma control program, particularly with regard to three major strategies: social mobilization, community strategy, and capacity building for health workers.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12948366/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147328969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Mosquito-borne diseases in the Republic of Djibouti: a review of the literature].","authors":"Abdoulgabar Abdourahman Omar, Oumnia Himmi","doi":"10.48327/mtsi.v5i4.2025.778","DOIUrl":"10.48327/mtsi.v5i4.2025.778","url":null,"abstract":"<p><strong>Introduction -justification: </strong>This article is part of a doctoral project that aims to describe the ecology of the mosquitoes present in Djibouti and how they interact with epidemiological dynamics. This study traces the historical evolution of mosquito-borne diseases in Djibouti based on a systematic review of the available scientific literature.</p><p><strong>Materials and methods: </strong>The study was conducted in accordance with PRISMA standards. An exhaustive bibliographic search was conducted on vector-borne diseases (arboviruses and parasitic diseases) transmitted by mosquitoes in the geographical context of the Republic of Djibouti. PubMed, ScienceDirect, Springer Nature, and Google Scholar were searched to cover both indexed publications and gray literature. The query syntax combined Boolean operators (AND/OR) and MeSH/relevant entry terms structured around two axes: \"French Territory of the Afars and the Issas\" and \"Djibouti,\" as well as \"Dengue Djibouti,\" \"Malaria Djibouti,\" etc.</p><p><strong>Results: </strong>In Djibouti, the risk of arbovirus infection is primarily linked to environmental and behavioral risk factors, with a higher risk in urban areas than in rural regions. The scientific literature lists at least six vector-borne diseases transmitted by female mosquito bites. Four of these diseases have been documented in Djibouti: malaria, chikungunya, dengue, and West Nile fever. Rift Valley fever and Zika virus are also mentioned, though there have been no official reports of Zika virus cases in the country to date.</p><p><strong>Discussion -conclusion: </strong>Mosquito-borne diseases are dominated by malaria and dengue fever. This explains the abundance of data on these two diseases and their vectors. To better understand the health challenges, studies on the characterization of pathogens and other mosquito-borne diseases in Djibouti, as well as on the reporting of clinical signs, are strongly recommended.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12957994/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147367817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[34<sup>th</sup> STPI National Congress - 1<sup>st</sup> Middle East and North Africa Region Congress of clinical microbiology and infectious pathology May 22-24, 2025, Hammamet, Tunisia].","authors":"Pr Adnene Toumi","doi":"10.48327/mtsi.v5i4.2025.777","DOIUrl":"https://doi.org/10.48327/mtsi.v5i4.2025.777","url":null,"abstract":"","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12948371/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147329026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Effect of awake prone positioning in non-intubated patients with community-acquired pneumonia complicated by hypoxemia].","authors":"Karama Bouchaala, Mabrouk Bahloul, Sabrine Bradai, Rania Ammar, Chokri Ben Hamida","doi":"10.48327/mtsi.v5i4.2025.772","DOIUrl":"10.48327/mtsi.v5i4.2025.772","url":null,"abstract":"<p><strong>Introduction: </strong>Several studies have suggested that the early use of awake prone positioning (PP) in patients with acute respiratory failure due to severe community-acquired pneumonia, hemodynamically stable and alert, may improve oxygenation and avoid the need for invasive mechanical ventilation. PP may also help reduce case fatality rate (CFR). The benefits of PP for oxygen-dependent patients hospitalized with non-intubated acute respiratory failure due to SARS-CoV-2 infection have been evaluated. We reviewed the literature to determine if PP could improve hypoxemia and signs of acute respiratory failure in patients with community-acquired or non-community-acquired pneumonia, reduce the need for invasive mechanical ventilation, and reduce CFRin patients with Covid-19.</p><p><strong>Materials and methods: </strong>We searched with Medline for articles published in French or English containing the keywords \"acute respiratory failure\" or \"acute respiratory distress\" and \"prone position.\"Results/Conclusion. Turning into prone position is a simple, inexpensive, and effective technique that improves the prognosis of patients with respiratory distress due to severe community-acquired pneumonia, regardless of the cause. This technique can be easily implemented in low-and middle-income countries, particularly in North Africa, sub-Saharan Africa, Asia, and South America.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12957996/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147367774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}