Medecine tropicale et sante internationale最新文献

筛选
英文 中文
[Profile of mpox cases identified during surveillance of the Kokolo health zone in Kinshasa (DRC) from August to November 2024]. [2024年8月至11月在金沙萨(刚果民主共和国)科科罗卫生区监测期间发现的麻疹病例概况]。
Medecine tropicale et sante internationale Pub Date : 2025-03-25 eCollection Date: 2025-03-31 DOI: 10.48327/mtsi.v5i1.2025.604
Levis Amisi Kengea, Blanche Ihekambangu Ngwakaha, Winnie Masamba Bikoki, Vally Ndumbi Temuangudi, Jean Claude Nsinga Bungiena, Jean-Jacques Kape Kalume, Anthony Mbuyi Mutombe, Angèle Wumba Mavinga
{"title":"[Profile of mpox cases identified during surveillance of the Kokolo health zone in Kinshasa (DRC) from August to November 2024].","authors":"Levis Amisi Kengea, Blanche Ihekambangu Ngwakaha, Winnie Masamba Bikoki, Vally Ndumbi Temuangudi, Jean Claude Nsinga Bungiena, Jean-Jacques Kape Kalume, Anthony Mbuyi Mutombe, Angèle Wumba Mavinga","doi":"10.48327/mtsi.v5i1.2025.604","DOIUrl":"https://doi.org/10.48327/mtsi.v5i1.2025.604","url":null,"abstract":"<p><strong>Introduction: </strong>The Kokolo military health zone in the city of Kinshasa (DRC) is one of the areas affected by mpox, with the presence of two subclades Ia and Ib of the monkeypox virus. This study presents the results of mpox-related surveillance activities in this area.</p><p><strong>Methods: </strong>Descriptive study of data reported by the surveillance system on the mpox epidemic in the Kokolo health zone between August and November 2024.</p><p><strong>Results: </strong>Of 202 specimens (143 males, sex ratio 0.71) from individuals clinically suspected of having mpox or contacts of known cases, 25.2% were positive by PCR at the National Institute for Biomedical Research laboratory (median age 25 years, IQR 11-31). Subjects aged 18 years and older were most affected, i.e. 41/51 (80%). Of these 51 confirmed cases, 13 (26%) and 10 (20%) were from the Kokolo 2 health areas and the Kokolo camp logistics base, respectively. All confirmed cases presented with rash. Other reported symptoms were myalgia (50/51, 98%), genital rash (42/51, 82%), arthralgia (42/51, 82%), and headache (41/51, 80%). The median length of stay at the mpox treatment center was 10 days (IQR: 7-9).</p><p><strong>Conclusions: </strong>This study showed that of 202 tests performed on persons suspected of having mpox or contacts of known cases, 25.2% were positive by PCR. All confirmed cases presented with rash, with other common symptoms including myalgia, genital rash, arthralgia, and headache. These results underscore the need to strengthen surveillance and control measures for the spread of mpox, particularly in the most affected health care settings.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001985/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144034825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Origin of Syphilis in Europe: End of a Controversy?] 梅毒在欧洲的起源:争论的结束?]
Medecine tropicale et sante internationale Pub Date : 2025-03-21 eCollection Date: 2025-03-31 DOI: 10.48327/mtsi.v5i1.2025.666
Jean-Paul Louis, Francis Louis
{"title":"[Origin of Syphilis in Europe: End of a Controversy?]","authors":"Jean-Paul Louis, Francis Louis","doi":"10.48327/mtsi.v5i1.2025.666","DOIUrl":"https://doi.org/10.48327/mtsi.v5i1.2025.666","url":null,"abstract":"<p><p>Upon Christopher Columbus's return, an unknown disease was discovered in Barcelona, Spain, in 1493, before appearing in Naples, Italy, in 1494/1495 during a war with France. Initially described among the troops, it quickly spread throughout Europe as the armies withdrew. The question arises whether there is a cause-and-effect relationship with Columbus's return to Spain or if it is merely a coincidence, as syphilis seems to have been present in Europe before Europeans arrived in the Americas, though it may not have been identified as such. This would explain why it was not clearly recognized by the population or described in the available literature. Recently, archaeological and paleopathological research on human remains from the modern era, supported by genetic data, has clearly established the presence of syphilis in ancient Europe. These findings also suggest that syphilis may not have existed in the Americas during Columbus's time. However, it seems possible that Columbus's companions brought back to Europe a non-venereal strain of treponematosis, which could have mutated while adapting to new environmental conditions, increasing its pathogenicity and altering its mode of transmission when transferred to new individuals, possibly prostitutes. In turn, this venereal syphilis strain may have infected the American continent during the Spanish conquests and/or the transatlantic slave trade. This study provides some recent arguments to fuel the controversy.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001989/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144040671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Malaria control in French Guiana: What are the challenges in this last endemic French territory in 2024?] [法属圭亚那的疟疾控制:2024年这片最后的法国领地将面临哪些挑战?]]
Medecine tropicale et sante internationale Pub Date : 2025-03-20 eCollection Date: 2025-03-31 DOI: 10.48327/mtsi.v5i1.2025.536
Laureen Dahuron, Lise Musset, Hélène Tréhard, Alice Sanna, Aïssata Dia, Yassamine Lazrek, Richard Naldjinan-Kodbaye, Virginie Cébrian, Luisiane Carvalho, Yannick Andro, Bérengère Bonot, Mathilde Boutrou, Olivier Lesens, Paul Le Turnier, Philippe Abboud, Brice Daverton, Francky Mubenga, Margot Oberlis, Jean-Bernard Duchemin, Félix Djossou, Delphine Patarot, Joseph Rwagitinywa, Émilie Mosnier, Maylis Douine, Loïc Epelboin
{"title":"[Malaria control in French Guiana: What are the challenges in this last endemic French territory in 2024?]","authors":"Laureen Dahuron, Lise Musset, Hélène Tréhard, Alice Sanna, Aïssata Dia, Yassamine Lazrek, Richard Naldjinan-Kodbaye, Virginie Cébrian, Luisiane Carvalho, Yannick Andro, Bérengère Bonot, Mathilde Boutrou, Olivier Lesens, Paul Le Turnier, Philippe Abboud, Brice Daverton, Francky Mubenga, Margot Oberlis, Jean-Bernard Duchemin, Félix Djossou, Delphine Patarot, Joseph Rwagitinywa, Émilie Mosnier, Maylis Douine, Loïc Epelboin","doi":"10.48327/mtsi.v5i1.2025.536","DOIUrl":"https://doi.org/10.48327/mtsi.v5i1.2025.536","url":null,"abstract":"<p><p>French Guiana, the last malaria-endemic region of France, is facing an epidemic resurgence of malaria since the end of 2023. This epidemic, primarily caused by <i>Plasmodium vivax</i>, mainly affects populations that are far from the healthcare system. It has highlighted the difficulties of providing a full course of treatment. This includes both curative treatment with artemisinin derivatives (following the withdrawal of chloroquine from the market) and eradicative treatment with primaquine, with the challenge of excluding G6PD deficiency. The aim of this paper is to describe the problems of malaria diagnosis and management in this unique territory, to highlight the adaptations made and to propose diagnostic, therapeutic and follow-up schemes adapted to the possibilities of access to the health system, with a view to homogenizing practices. This article also highlights the innovative strategies implemented in French Guiana to deal with this new epidemic: health mediation, mobile malaria team, rapid diagnostic tests and immediate out-of-hospital treatment Test and Treat, development of self-diagnosis and self-treatment. These proposals are part of a campaign to eliminate malaria in France in the short term.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001996/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Analysis of retention in care for people living with HIV in Togo: results of a survey conducted in 2021]. [对多哥艾滋病毒感染者护理保留情况的分析:2021年进行的一项调查结果]。
Medecine tropicale et sante internationale Pub Date : 2025-03-13 eCollection Date: 2025-03-31 DOI: 10.48327/mtsi.v5i1.2025.664
Abla Sefako Akakpo, Julienne Noude Teclessou, Kodjo Deku, Jean-Paul Tchupo, Souley Wade, Didier Koumavi Ekouevi, Zakilatou Adam, Anoumou Yawotsè Dagnra, Palokinam Pitché
{"title":"[Analysis of retention in care for people living with HIV in Togo: results of a survey conducted in 2021].","authors":"Abla Sefako Akakpo, Julienne Noude Teclessou, Kodjo Deku, Jean-Paul Tchupo, Souley Wade, Didier Koumavi Ekouevi, Zakilatou Adam, Anoumou Yawotsè Dagnra, Palokinam Pitché","doi":"10.48327/mtsi.v5i1.2025.664","DOIUrl":"https://doi.org/10.48327/mtsi.v5i1.2025.664","url":null,"abstract":"<p><strong>Introduction: </strong>The aim of our study was to analyze retention in care and survival at 12, 24, and 36 months among people living with HIV (PLWH) on antiretroviral therapy (ART).</p><p><strong>Methods: </strong>This is a retrospective cross-sectional analysis of a cohort of PLWH aged 15 years and older who started ART. Purposive sampling was used, taking into account the activities of different health centers and budgetary constraints (quantitative approach). In-depth individual interviews and focus groups were also conducted (qualitative approach).</p><p><strong>Results: </strong>During the study period, 2,100 HIV-infected patients were enrolled. The median age of patients was 44 years (interquartile range (IQR) [36-51]), with a statistically significant difference according to sex (p< 0.001), with women being younger than men (42 <i>versus</i> 46 years). The median duration of ART was 5 years (IQR [2-8]) with no statistical difference by gender (p=0.752). At baseline, 20.5% (n=431) and 25.1% (n=509) were lost to follow-up (LTF) 90 days and 28 days after scheduled visit, respectively. There were 146 adult deaths, for a crude mortality rate of 6.9% (95% CI [5.9-8.1]). Approximately 60% of the 158 PLWH randomly selected from our LTF patients could be reached by telephone. They reported that they were still in care. Retention in care was 72.5%, and the probability of retention was 91.6% at 12 months, 87.8% at 24 months, and 78.7% at 60 months. Retention in care was more pronounced among women and more significant among PLWH aged 35 years and older when treatment was initiated in health care facilities offering the full range of activities (care and treatment, active patient search, presence of social mediators).</p><p><strong>Conclusion: </strong>Our study, conducted during the Covid-19 pandemic, shows acceptable retention rates in care for PLWH. These results make possible to propose solutions to improve the care program in the country: the harmonization of procedures for tracing PLWH with the implementation of their active search (with the help of community mediators) and the dispensing of ART to PLWH for three or six months.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12012725/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144031027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Sexual transmission of strongyloidiasis in men who have sex with men (MSM) in Paris]. [巴黎男男性行为者(MSM)中类圆线虫病的性传播]。
Medecine tropicale et sante internationale Pub Date : 2025-03-05 eCollection Date: 2025-03-31 DOI: 10.48327/mtsi.v5i1.2025.660
Michel Develoux, Martin Siguier, Christophe Hennequin, Gilles Pialoux
{"title":"[Sexual transmission of strongyloidiasis in men who have sex with men (MSM) in Paris].","authors":"Michel Develoux, Martin Siguier, Christophe Hennequin, Gilles Pialoux","doi":"10.48327/mtsi.v5i1.2025.660","DOIUrl":"https://doi.org/10.48327/mtsi.v5i1.2025.660","url":null,"abstract":"<p><strong>Introduction: </strong>The sexual transmission of intestinal parasites has been reported for a long time, even before the HIV pandemic. It mainly involves protozoa. More rarely, helminths are involved: <i>Strongyloides stercoralis, Enterobius vermicularis.</i> This type of transmission is almost exclusively observed in men who have sex with men (MSM) through direct oral-genital-anal sexual contact.</p><p><strong>Observations: </strong>We present four cases of sexually transmitted strongyloidiasis in MSM.</p><p><strong>Discussion: </strong>Several associated factors were found: HIV infection, recurrent episodes of other sexually transmitted infections, or risk factors: sexual relations with men from regions endemic for <i>S. stercoralis</i>, rimming, chemsex, scatological practices. In MSM, strongyloidiasis must be considered and investigated in the presence of eosinophilia, which may be fluctuating, with or without digestive and/or cutaneous signs, even in the absence of a stay in a tropical zone.</p><p><strong>Conclusion: </strong>These MSM patients must be thoroughly questioned, with details of their sexual behavior leading to appropriate prophylactic advice, such as unprotected oral-genital-anal intercourse.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001986/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144001640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Submicroscopic Plasmodium spp. Infections in Febrile Patients in Togo]. [多哥发热病人亚显微疟原虫感染]。
Medecine tropicale et sante internationale Pub Date : 2025-02-27 eCollection Date: 2025-03-31 DOI: 10.48327/mtsi.v5i1.2025.553
Diwaba Carmel Teou, Essoham Ataba, Smaila Alidou, Kossi Yakpa, Efoe Sossou, Manani Hemou, Agueregna Abdou-Kerim, Awèréou Kotosso, Lidaw Déassoua Bawe, Didier Ménard, Ameyo Monique Dorkenoo
{"title":"[Submicroscopic <i>Plasmodium</i> spp. Infections in Febrile Patients in Togo].","authors":"Diwaba Carmel Teou, Essoham Ataba, Smaila Alidou, Kossi Yakpa, Efoe Sossou, Manani Hemou, Agueregna Abdou-Kerim, Awèréou Kotosso, Lidaw Déassoua Bawe, Didier Ménard, Ameyo Monique Dorkenoo","doi":"10.48327/mtsi.v5i1.2025.553","DOIUrl":"https://doi.org/10.48327/mtsi.v5i1.2025.553","url":null,"abstract":"<p><strong>Objective: </strong>Submicroscopic <i>Plasmodium</i> infections, mostly undetected by routine diagnostic techniques, represent a potential reservoir that contributes to the continued transmission of malaria in the community. To achieve the World Health Organization's goal of malaria elimination, it is therefore essential to identify all parasite carriers and treat them effectively with recommended antimalarial drugs. The aim of this study was to estimate the proportion of submicroscopic <i>Plasmodium</i> spp. infections not detected by microscopy in symptomatic patients with suspected malaria attending health centers in Togo, and to identify the factors associated with it.</p><p><strong>Materials and methods: </strong>A cross-sectional study was conducted between September 2021 and January 2022 and between July and December 2022 in three health facilities in Togo. Each patient suspected of having malaria had a capillary blood sample taken for detection of <i>Plasmodium</i> species by thick blood film/blood smear (TBF/BS) and PCR. A logistic regression model was used to evaluate the factors linked to the parasitic results.</p><p><strong>Results: </strong>A total of 553 participants were selected, 44.6% of whom were female, with a median age of 25 years (± 2 years). The proportion of <i>Plasmodium</i> spp. infections detected by TBF/BS was 25% and by PCR 29.1%. The frequency of submicroscopic <i>Plasmodium</i> spp. infections detected by PCR in patients with negative microscopic TBF/BS was 5.5% (23/415) [95% CI: 3.7-8.2], and <i>P. falciparum</i> was the most common species (83%, 19/23, 95% CI: 60-94). Participants from the Anié and Kouvé sites were more likely to have submicroscopic infections.</p><p><strong>Conclusion: </strong>This study provides preliminary data on the incidence of submicroscopic <i>Plasmodium</i> infections in Togo.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001993/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Treatment and clinical course of autoimmune myasthenia in Burkina Faso]. 布基纳法索自身免疫性肌无力的治疗和临床病程
Medecine tropicale et sante internationale Pub Date : 2025-02-21 eCollection Date: 2025-03-31 DOI: 10.48327/mtsi.v5i1.2025.646
Lompo Djingri Labodi, Adeline Julie Marie Kyelem, Alassane Zoungrana, M Fabienne Yabtouta Kere, Melody Zeinab Gnampa, Hervé Nacoulma, Christian Napon, Athanase Millogo
{"title":"[Treatment and clinical course of autoimmune myasthenia in Burkina Faso].","authors":"Lompo Djingri Labodi, Adeline Julie Marie Kyelem, Alassane Zoungrana, M Fabienne Yabtouta Kere, Melody Zeinab Gnampa, Hervé Nacoulma, Christian Napon, Athanase Millogo","doi":"10.48327/mtsi.v5i1.2025.646","DOIUrl":"https://doi.org/10.48327/mtsi.v5i1.2025.646","url":null,"abstract":"<p><strong>Introduction: </strong>In sub-Saharan Africa, autoimmune myasthenia gravis (AMG) is still poorly known and underdiagnosed (delayed diagnosis, poor availability and accessibility of proven effective diagnostic and therapeutic tools), resulting in a poor functional prognosis and high mortality. The aim of the present study was to evaluate the therapeutic and clinical course of AMG in Burkina Faso.</p><p><strong>Patients and methods: </strong>This was a longitudinal, multicenter study conducted from March 2015 to April 2023. It included patients with clinical signs suggestive of myasthenia associated with the presence of serum anti-acetylcholine receptor (anti-RACh) antibodies and/or anti-muscle specific kinase (anti-MuSK) antibodies, and/or with the presence of a decrease >10% on electroneuromyography, and/or with a positive therapeutic test to oral anticholinesterase drugs. Data on treatment modalities and clinical evolution were analyzed using Epi InfoTM 7.2.5.0 software. Bivariate analysis with p-value calculation (<0.05) was used to identify factors associated with adverse clinical outcome.</p><p><strong>Results: </strong>A total of 40 patients with AMG were included, with a female predominance (60%). The median age of onset was 25 years (IQ=7). The median time to neurological consultation and diagnosis was 21 months (IQ=12) and 22 months (IQ=12), respectively. The disease affected young adults in 85% of cases and was generalized in 35 cases. Anti-RACh and anti-MuSK antibodies were present in 22 and 4 of 33 patients, respectively. Thymic hyperplasia and thymoma were found on chest CT in 22 and 6 of 38 patients, respectively. All patients received symptomatic treatment with oral anticholinesterase agents and 36 patients received background treatment with corticosteroids and/or immunosuppressants (azathioprine). Four of 9 patients received a course of intravenous immunoglobulin (IVIG) or plasma exchange (PE) for myasthenic crises. Thymectomy was performed in 16 of the 40 patients. At the end of a median outpatient follow-up of 53 months (IQ=16), of the 40 patients included in the study, 6 (15%) had died, 14 (35%) were in stable clinical remission, and 17 (43%) had partial clinical improvement.</p><p><strong>Conclusion: </strong>AMG suffers from delayed diagnosis in Burkina Faso. Almost all patients treated for AMG receive anticholinesterase and corticosteroid therapy alone or in combination with azathioprine. Access to IVIG, PE and thymectomy remains limited. Mortality occurs in nearly one in six patients, and stable clinical remission affects only about one third of patients. To improve the prognosis, we need to make available and accessible diagnostic tools and treatments of proven efficacy, such as thymectomy, immunosuppressants, IVIG and PE.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001994/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144051955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Time of entry into care of people living with HIV in two outpatient treatment centers of Libreville, Gabon, between 2012 and 2020]. [2012年至2020年间,加蓬利伯维尔两个门诊治疗中心对艾滋病毒感染者进行治疗的时间]。
Medecine tropicale et sante internationale Pub Date : 2025-02-11 eCollection Date: 2025-03-31 DOI: 10.48327/mtsi.v5i1.2025.537
Michèle Marion Ntsame Owono, Magalie Essomeyo Ngue Mebale, Charleine Manomba Boulingui, Bridy Moutombi Ditombi, Philomène Kouna Ndouongo, Marielle Karine Bouyou Akotet
{"title":"[Time of entry into care of people living with HIV in two outpatient treatment centers of Libreville, Gabon, between 2012 and 2020].","authors":"Michèle Marion Ntsame Owono, Magalie Essomeyo Ngue Mebale, Charleine Manomba Boulingui, Bridy Moutombi Ditombi, Philomène Kouna Ndouongo, Marielle Karine Bouyou Akotet","doi":"10.48327/mtsi.v5i1.2025.537","DOIUrl":"https://doi.org/10.48327/mtsi.v5i1.2025.537","url":null,"abstract":"<p><strong>Introduction: </strong>Delays in entry to care are a barrier to immediate initiation of antiretroviral therapy (ART) at diagnosis, as recommended by the World Health Organization. The aim of this study was to determine and compare delays in entry into care and associated factors among people living with HIV (PLHIV) seen at two outpatient treatment centers in Libreville between 2012 and 2020.</p><p><strong>Materials and methods: </strong>Retrospective study based on PLHIV records collected from January 2012 to March 2020 at the two largest outpatient treatment centers (CTA) in Libreville, that of the Centre Hospitalier Universitaire de Libreville (CHUL) and that of Nkembo Hospital. Early entry into care was defined as less than 28 days between diagnosis of HIV infection and first consultation at the CTA. Late entry was defined as more than three months. For analysis, patients were divided into two periods: 2012-2015, when treatment initiation was linked to CD4 count, and 2016-2020, the period when the <i>Test and Treat</i> method was introduced in Gabon.</p><p><strong>Results: </strong>A total of 979 patients were newly treated in the two CTAs, and the records of 672 individuals could be used. In 48.3% of the cases, HIV infection was diagnosed at a late stage (WHO 3 or 4). The median time to entry into care was 1.2 [IQ: 0-3] months after diagnosis of HIV infection. Between 2016 and 2020, 47% entered care in less than 28 days, compared with 35.7% in 2012-2015 (p < 0.01). The percentage of PLHIV with late entry into care was comparable between the two periods (14.4% vs. 15.9% in 2012-2015; p = 0.62). Factors associated with late entry were WHO stage 3, failure to achieve CD4 count, employment, and pregnancy (p<0.05).</p><p><strong>Conclusion: </strong>In the era of <i>Test and Treat</i> in Libreville, the delay in seeking care is still long. A better understanding of the associated factors and a decentralized, integrated approach to the management of HIV infection would make it possible to achieve the second pillar of \"95-95-95\" target in Libreville.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001990/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143997136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Patients' satisfaction in ENT surgery at the Sylvanus Olympio University Hospital in Lomé (Togo)]. [多哥lomoise的Sylvanus Olympio大学医院患者对耳鼻喉外科手术的满意度]。
Medecine tropicale et sante internationale Pub Date : 2025-01-29 eCollection Date: 2025-03-31 DOI: 10.48327/mtsi.v5i1.2025.638
Essobiziou Amana, Winga Foma, Guemessou Nassou, Gérémie Ananidjin, Bathokédéou Amana
{"title":"[Patients' satisfaction in ENT surgery at the Sylvanus Olympio University Hospital in Lomé (Togo)].","authors":"Essobiziou Amana, Winga Foma, Guemessou Nassou, Gérémie Ananidjin, Bathokédéou Amana","doi":"10.48327/mtsi.v5i1.2025.638","DOIUrl":"https://doi.org/10.48327/mtsi.v5i1.2025.638","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the satisfaction of patients surgically treated in a Otolaryngology Department in a developing country. This survey was caried out from consultation to surgical management in the Sylvanus Olympio University Hospital in Lomé.</p><p><strong>Patients and methods: </strong>Cross-sectional study from December 1, 2022 to November 30, 2023, a period of one year. People included were the patients or relatives for under 18 years of age who gave their consent, seen by the surgical team and operated on in the department during this period. The parameters assessed by a closed self-administered questionnaire were related to satisfaction from admission to diagnosis, from preoperative evaluation to the day before surgery, from the day of surgery to the end of hospitalization, and finally to discharge formalities. The data were analyzed and processed using Epi info 7.2.5.0 software.</p><p><strong>Results: </strong>One hundred and twelve individuals, including fifteen relatives, met the survey criteria (70.4%). The mean age was 41 years, with extremes of 19 and 76 years. The participants had a secondary education level in 59.5% of the cases. They were shopkeepers and housewives in 26.8% and 24.1% of cases, respectively. Thyroidectomy was the most common type of surgery, performed in 43.7% of cases. From admission to diagnosis, 66.1% of patients found the service satisfactory, while 12.5% found it very poor. From the preoperative examination to the day before surgery, this examination and the purchase of prescriptions were judged to be poor in 33.9% and 40.2% of cases, respectively. From the day of the operation to discharge, the quality of the sanitary facilities and of the hospital ward was poor in 44.6% and 54.4% of cases, respectively. Participants were satisfied with the quality of visits (58.9%), behavior of medical-surgical team in the operating room (30.4%), follow-up information and surgical procedure in all cases.</p><p><strong>Conclusion: </strong>Dissatisfaction of patients and their relatives exists at all levels, administrative and medical. More efforts need to be done in our department to improve the quality of care.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001988/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Seroprevalence of Toxoplasma gondii in chicken of the Marrakech-Safi region, Morocco]. [摩洛哥马拉喀什-萨菲地区鸡刚地弓形虫血清流行率]。
Medecine tropicale et sante internationale Pub Date : 2025-01-17 eCollection Date: 2025-03-31 DOI: 10.48327/mtsi.v5i1.2025.633
Laila Hoummadi, Salma Berrouch, Oussama Dehhani, Denis Limonne, Pierre Flori, Redouane Moutaj, Jamal Eddine Hafid
{"title":"[Seroprevalence of <i>Toxoplasma gondii</i> in chicken of the Marrakech-Safi region, Morocco].","authors":"Laila Hoummadi, Salma Berrouch, Oussama Dehhani, Denis Limonne, Pierre Flori, Redouane Moutaj, Jamal Eddine Hafid","doi":"10.48327/mtsi.v5i1.2025.633","DOIUrl":"https://doi.org/10.48327/mtsi.v5i1.2025.633","url":null,"abstract":"<p><strong>Introduction: </strong><i>Toxoplasma gondii (T. gondii)</i> is an obligate intracellular parasite that infects a wide range of animal species, including humans and livestock. Contamination can have significant health, economic and epidemiological consequences. Birds in general, and poultry in particular, appear to play an important role in the epidemiology and circulation of the parasite. The aim of this study was to determine, for the first time, the seroprevalence of <i>T.gondii</i> in chicken in the Marrakech-Safi region.</p><p><strong>Materials and methods: </strong>Sera were collected between January 2019 and March 2020 from 486 chickens from three types of farming: 122 traditional (domestic) chickens, 109 free-range chickens, and 255 commercial (battery) chickens intended for consumption in the Marrakech-Safi region. Immunoglobulin Y (IgY) testing was performed by ELISA using a total <i>T. gondii</i> antigen.</p><p><strong>Results: </strong>The mean seroprevalence of <i>T.gondii</i> in chicken in the study region was 30.65%. This study also showed a significant association (p<0.0001) between seroprevalence and type of farming: domestic chickens had a higher seroprevalence than free-range and commercial chickens.The high seropositivity in chicken could be explained by the widespread presence of <i>T. gondii</i> oocysts and/or cysts in their environment and diet.</p><p><strong>Conclusion: </strong>Consumption of undercooked or uncooked poultry products may be a source of potential contamination for humans and carnivores, including cats.</p>","PeriodicalId":101416,"journal":{"name":"Medecine tropicale et sante internationale","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001991/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信