[对多哥艾滋病毒感染者护理保留情况的分析:2021年进行的一项调查结果]。

Medecine tropicale et sante internationale Pub Date : 2025-03-13 eCollection Date: 2025-03-31 DOI:10.48327/mtsi.v5i1.2025.664
Abla Sefako Akakpo, Julienne Noude Teclessou, Kodjo Deku, Jean-Paul Tchupo, Souley Wade, Didier Koumavi Ekouevi, Zakilatou Adam, Anoumou Yawotsè Dagnra, Palokinam Pitché
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引用次数: 0

摘要

本研究的目的是分析接受抗逆转录病毒治疗(ART)的HIV感染者(PLWH)在12、24和36个月的护理保留和生存率。方法:这是一项对15岁及以上开始ART治疗的PLWH队列的回顾性横断面分析。考虑到不同保健中心的活动和预算限制(定量方法),采用了有目的的抽样。深入的个人访谈和焦点小组也进行了(定性方法)。结果:在研究期间,有2,100名艾滋病毒感染者入组。患者年龄中位数为44岁(四分位间距(IQR)[36-51]),性别差异有统计学意义(p< 0.001),女性年龄小于男性(42岁vs 46岁)。ART治疗的中位持续时间为5年(IQR[2-8]),性别差异无统计学意义(p=0.752)。在基线时,20.5% (n=431)和25.1% (n=509)分别在预定访问后90天和28天失去随访(LTF)。有146例成人死亡,粗死亡率为6.9% (95% CI[5.9-8.1])。从我们的LTF患者中随机选择的158名PLWH中约有60%可以通过电话联系到。他们报告说他们仍在接受治疗。留置率为72.5%,12个月留置率为91.6%,24个月留置率为87.8%,60个月留置率为78.7%。在提供全方位活动(护理和治疗、积极寻找病人、有社会调解人在场)的卫生保健机构开始治疗时,35岁及以上的妇女继续接受护理的情况更为明显。结论:我们的研究是在Covid-19大流行期间进行的,显示了PLWH护理的可接受保留率。这些结果使提出改善该国护理方案的解决方案成为可能:协调追踪艾滋病病毒感染者的程序,(在社区调解人的帮助下)实施积极搜索,并向艾滋病病毒感染者提供三到六个月的抗逆转录病毒药物治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Analysis of retention in care for people living with HIV in Togo: results of a survey conducted in 2021].

Introduction: The aim of our study was to analyze retention in care and survival at 12, 24, and 36 months among people living with HIV (PLWH) on antiretroviral therapy (ART).

Methods: This is a retrospective cross-sectional analysis of a cohort of PLWH aged 15 years and older who started ART. Purposive sampling was used, taking into account the activities of different health centers and budgetary constraints (quantitative approach). In-depth individual interviews and focus groups were also conducted (qualitative approach).

Results: During the study period, 2,100 HIV-infected patients were enrolled. The median age of patients was 44 years (interquartile range (IQR) [36-51]), with a statistically significant difference according to sex (p< 0.001), with women being younger than men (42 versus 46 years). The median duration of ART was 5 years (IQR [2-8]) with no statistical difference by gender (p=0.752). At baseline, 20.5% (n=431) and 25.1% (n=509) were lost to follow-up (LTF) 90 days and 28 days after scheduled visit, respectively. There were 146 adult deaths, for a crude mortality rate of 6.9% (95% CI [5.9-8.1]). Approximately 60% of the 158 PLWH randomly selected from our LTF patients could be reached by telephone. They reported that they were still in care. Retention in care was 72.5%, and the probability of retention was 91.6% at 12 months, 87.8% at 24 months, and 78.7% at 60 months. Retention in care was more pronounced among women and more significant among PLWH aged 35 years and older when treatment was initiated in health care facilities offering the full range of activities (care and treatment, active patient search, presence of social mediators).

Conclusion: Our study, conducted during the Covid-19 pandemic, shows acceptable retention rates in care for PLWH. These results make possible to propose solutions to improve the care program in the country: the harmonization of procedures for tracing PLWH with the implementation of their active search (with the help of community mediators) and the dispensing of ART to PLWH for three or six months.

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