The Turkish journal of pediatrics最新文献

{"title":"Exploring the link between adenovirus infection and Guillain-Barré syndrome in children: a case-based analysis.","authors":"Gulrukh Tuychiboeva, İbrahim Öncel, Gökçen Çoban Çifci, Ali Bülent Cengiz, Kübra Aykaç","doi":"10.24953/turkjpediatr.2026.6729","DOIUrl":"10.24953/turkjpediatr.2026.6729","url":null,"abstract":"<p><strong>Background: </strong>Adenovirus infections are commonly associated with respiratory tract infections, conjunctivitis, gastrointestinal disturbances, and in some cases, more severe illnesses such as pneumonia. Guillain-Barré syndrome (GBS), a rare autoimmune disorder that causes progressive peripheral nerve inflammation and paralysis, has been linked to various infections, including viral ones.</p><p><strong>Case presentation: </strong>We describe two newly diagnosed pediatric cases of GBS following adenovirus infection. Both patients were previously healthy boys, aged 3 and 6 years. Adenovirus was detected by nasopharyngeal PCR shortly preceding the neurological manifestations. Both were treated with intravenous immunoglobulin (IVIG); one also required plasma exchange and respiratory support. Both recovered fully during follow-up. Additionally, a relevant case from the literature was reviewed for comparison. Treatment included respiratory support, IVIG and plasma exchange therapy. During the 12-month follow-up no severe complications were observed in our patients.</p><p><strong>Conclusions: </strong>In conclusion, while GBS is a well-established complication of several viral infections, including adenovirus, the association between adenovirus and GBS remains relatively underexplored. Our case reports, along with a review of the literature, highlight the rare but plausible link between adenovirus infection and the development of GBS. Although adenovirus infections are common, the occurrence of GBS following these infections appears to be uncommon, suggesting that additional factors may be at play. However, given the potential severity of GBS and the growing body of evidence, it is important for clinicians to remain vigilant for this rare complication in patients with a history of adenovirus infection.</p>","PeriodicalId":101314,"journal":{"name":"The Turkish journal of pediatrics","volume":"68 1","pages":"150-155"},"PeriodicalIF":0.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147505895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Full-text publication outcomes of oral abstracts presented at the Turkish National Pediatric Congresses.","authors":"Sinem Akgül, Özge Başaran, Melis Pehlivantürk Kızılkan, Gülen Eda Ütine, Leman Akcan Yıldız, Yılmaz Yıldız, Ali Düzova, Enver Hasanoğlu","doi":"10.24953/turkjpediatr.2026.7526","DOIUrl":"10.24953/turkjpediatr.2026.7526","url":null,"abstract":"<p><strong>Background: </strong>Scientific congresses are critical platforms for knowledge dissemination and collaboration. The scientific value of presented abstracts is best demonstrated through their subsequent publication as full-text articles in peer-reviewed journals. This study aimed to evaluate the publication rate and characteristics of oral abstracts presented at the Turkish National Pediatric Congresses (TNPC) between 2019 and 2023.</p><p><strong>Methods: </strong>Abstract books of five consecutive congresses were reviewed. The publication status of each abstract was determined through systematic searches in Web of Science, PubMed, Scopus, Google Scholar and the TR Index utilizing the title, keywords from the title and author names. Parameters such as study design, collaboration type, index status and the impact factor of the journal, the year it was published, and time to publication were analyzed. Additionally, the subspecialty of each abstract and the publication rate for each subspecialty were evaluated.</p><p><strong>Results: </strong>Among 268 oral abstracts, 111 (41.8%) were published as full-text articles. Of these, 66 (59.5%) were published in journals indexed in the Science Citation Index Expanded. Approximately one-third (32.4%) of the articles were published in Q1 or Q2 ranked journals. The average impact factor was 1.72 ± 1.26 and the mean time to publication was 1.6 ± 1.17 years. The most common study design published was retrospective (51.3%), and the majority were single-center studies (88.3%). The highest publication rates were observed in the fields of rheumatology, adolescent medicine, and infectious diseases.</p><p><strong>Conclusion: </strong>A significant portion of the papers presented at TNPC congresses are published in peer-reviewed scientific journals. The fact that more than one-third of the published studies appear in high-impact journals demonstrates the academic quality of the papers presented at the congresses and the effectiveness of the selective evaluation process. The findings provide valuable contributions to the monitoring and development of academic productivity in the field of pediatrics in Türkiye.</p>","PeriodicalId":101314,"journal":{"name":"The Turkish journal of pediatrics","volume":"68 1","pages":"18-24"},"PeriodicalIF":0.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147505920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pediatric cervicofacial actinomycosis presenting with mandibular osteomyelitis: a diagnostic and therapeutic challenge and literature review.","authors":"Sema Yildirim Arslan, Sefa Tigrak, Emrah Yucel, Mahmut Demirci, Ozlem Ekici","doi":"10.24953/turkjpediatr.2026.6451","DOIUrl":"10.24953/turkjpediatr.2026.6451","url":null,"abstract":"<p><strong>Background: </strong>Actinomycotic osteomyelitis is a rare, chronic infection caused by Actinomyces species, anaerobic bacteria normally found in the oral flora. Mandibular involvement is uncommon and may mimic malignancies, complicating diagnosis.</p><p><strong>Case presentation: </strong>A 15-year-old previously healthy male presented with painful neck swelling and trismus. Examination revealed a firm mass at the angle of the mandible. Imaging suggested osteomyelitis but raised concern for malignancy. Surgical drainage was performed, and histopathology confirmed actinomycotic infection. The patient initially received empirical intravenous vancomycin, cefotaxime, and metronidazole. Due to persistent fever and elevated inflammatory markers, the regimen was switched to teicoplanin plus piperacillin/tazobactam. Therapy was subsequently escalated to meropenem due to recurrent fever and based on magnetic resonance imaging findings suggestive of osteomyelitis, then vancomycin was replaced with teicoplanin because of vancomycin-associated nephrotoxicity. Following clinical improvement, the patient was discharged on oral amoxicillin/clavulanate to complete a total of six weeks of therapy.</p><p><strong>Discussion: </strong>Pediatric mandibular actinomycotic osteomyelitis is extremely rare. Its indolent course often mimics tumors or granulomatous disease. In this case, delayed diagnosis and nonspecific imaging findings led to initial misinterpretation. Surgical intervention played a key role in diagnosis and treatment. Early recognition and combined medical-surgical management are crucial to avoid complications. This case highlights the importance of considering infectious causes in mandibular masses and underscores the diagnostic challenges associated with them.</p>","PeriodicalId":101314,"journal":{"name":"The Turkish journal of pediatrics","volume":"68 1","pages":"156-163"},"PeriodicalIF":0.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147505948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Author Correction to: \"Turkish pediatricians' knowledge, attitudes, and awareness of respiratory syncytial virus (RSV) infection and immunization strategies: a cross-sectional study.\" [Turk J Pediatr 2025; 67: 153-161.].","authors":"İsmail Yıldız, Erdem Gönüllü, Sıla Yılmaz, Elvan Zengin, Osman Yeşilbaş, Ahmet Soysal","doi":"10.24953/turkjpediatr.2026.8115","DOIUrl":"https://doi.org/10.24953/turkjpediatr.2026.8115","url":null,"abstract":"","PeriodicalId":101314,"journal":{"name":"The Turkish journal of pediatrics","volume":"68 1","pages":"173"},"PeriodicalIF":0.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147505831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Problematic social media use and eating behaviors in adolescence: gender-based differences.","authors":"Büşra Başar Gökcen, Ozan Fırat Varol","doi":"10.24953/turkjpediatr.2026.7083","DOIUrl":"10.24953/turkjpediatr.2026.7083","url":null,"abstract":"<p><strong>Background: </strong>Adolescence is a key period for shaping eating behaviors. Social media, central to identity formation and peer interaction, may influence diet through appearance-related mechanisms, with possible gender differences. This study investigated associations between social media use, addiction, and disorder with eating behaviors among Turkish adolescents, focusing on the mediating role of appearance-related social media consciousness.</p><p><strong>Methods: </strong>A cross-sectional survey was conducted with 487 high school students aged 14-18 years in Manavgat, Antalya, Türkiye. Measures included the Social Media Addiction Scale for Adolescents (SMASA), Social Media Disorder Scale (SMDS), Appearance-Related Social Media Consciousness Scale (ASMC), Scale of Effects of Social Media on Eating Behavior (SESMEB) and Eating Habits Questionnaire for Adolescents (EHQA). Non-parametric tests were used due to non-normal data distributions; gender-stratified multiple regression models identified independent predictors of unhealthy eating habits. Simple mediation analyses (PROCESS Model 4) were performed to test indirect effects, as mediation models allow evaluation of whether ASMC explains the pathway between social media-related variables and unhealthy eating.</p><p><strong>Results: </strong>Female adolescents reported longer daily social media use than males (median = 3.0 vs. 2.0 hours, p < 0.05). Across genders, healthy eating (EHQA) was negatively correlated with ASMC and SESMEB (all p < 0.01). Regression analyses showed that SMDS, ASMC, and SESMEB were significant predictors of unhealthy eating among females, while ASMC and SESMEB predicted unhealthy eating among males. Mediation analyses showed partial mediation in females in both models (SMASA → ASMC → EHQA; SMDS → ASMC → EHQA), with both direct and indirect effects being significant. In males, direct effects were non-significant, whereas indirect effects were significant.</p><p><strong>Conclusions: </strong>Problematic social media use was associated with unhealthy eating among adolescents. In females, both direct and indirect (appearance-related social media consciousness-mediated) effects were observed, whereas in males the association was indirect only. Gender-specific psychological mechanisms should be considered in developing interventions to promote healthier digital engagement and eating behaviors in adolescence.</p>","PeriodicalId":101314,"journal":{"name":"The Turkish journal of pediatrics","volume":"68 1","pages":"38-53"},"PeriodicalIF":0.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147505935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative analysis of surgical costs vs. theoretical tiopronin therapy in pediatric cystinuria: a single-center experience from Türkiye.","authors":"Sümeyye Sözduyar, Hilmican Ulman, Ali Tekin, İbrahim Ulman, Sibel Tiryaki","doi":"10.24953/turkjpediatr.2026.6198","DOIUrl":"10.24953/turkjpediatr.2026.6198","url":null,"abstract":"<p><strong>Background: </strong>Cystinuria is a rare autosomal recessive disorder leading to recurrent cystine stone formation, often necessitating repeated surgical interventions. In Türkiye, tiopronin-a proven medical therapy-has become inaccessible since 2019, raising concerns about its economic and clinical consequences. This study aimed to compare the annual hospital costs of surgical management with the theoretical cost of tiopronin therapy in pediatric cystinuria patients.</p><p><strong>Methods: </strong>This single-center, retrospective study included 10 consecutive pediatric patients (median age: 12 years; range: 3-17 years) with genetically or biochemically confirmed cystinuria who underwent surgery for cystine stones in 2023. The annual cost of surgical management was calculated by summing all direct medical costs (operating room, anesthesia, devices, hospitalization, and related diagnostics) obtained from the hospital billing database. The theoretical annual cost of tiopronin therapy was calculated based on the last accessible market price of the drug in Türkiye, converted to Turkish Lira at the 2023 average exchange rate, and adjusted per patient using a standard dosing regimen of 15 mg/kg/day. Costs were compared using the Mann-Whitney U test.</p><p><strong>Results: </strong>The median annual surgical cost per patient was 49,936 TL (range: 14,791-84,576 TL), compared to a theoretical tiopronin cost of 27,923 TL (range: 9,307-27,925 TL). Surgical management was significantly more expensive than tiopronin therapy (p=0.001) in 9 of 10 cases. Six patients had a history of tiopronin use, and five of them experienced a surgery-free interval during medication (median duration: 3 years; range: 2-6 years). Preliminary follow-up data for 2024 revealed that 70% of patients required further surgical interventions (median: 2 surgeries per patient), demonstrating the persistent and recurrent nature of the disease when managed solely with surgery.</p><p><strong>Conclusion: </strong>Surgical treatment of cystinuria poses a substantially higher economic burden compared to tiopronin therapy. Our findings support the reintroduction of tiopronin into the Turkish healthcare system, particularly for pediatric patients with frequent stone recurrence.</p>","PeriodicalId":101314,"journal":{"name":"The Turkish journal of pediatrics","volume":"68 1","pages":"87-93"},"PeriodicalIF":0.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147505865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic significance of serum apelin-13 and galectin-3 concentrations as potential indicators of severity and mortality in pediatric acute respiratory distress syndrome.","authors":"Serçin Taşar, Nuri Alacakır, İsmail Bulut, Ayşe Esra Tapcı, Gül Kırtıl, Naz Koçoğlu, Rukiye Ünsal Saç, Medine Ayşin Taşar","doi":"10.24953/turkjpediatr.2026.6648","DOIUrl":"10.24953/turkjpediatr.2026.6648","url":null,"abstract":"<p><strong>Background: </strong>The predictive and prognostic significance of apelin and galectin-3 as biomarkers in pediatric acute respiratory distress syndrome (PARDS) and lung injury has remained limited. This study examined the association between serum apelin-13 and galectin-3 levels, PARDS severity, and patient outcomes.</p><p><strong>Methods: </strong>The study included children aged 1 month to 18 years diagnosed with PARDS on admission to a pediatric intensive care unit, alongside age- and sex-matched outpatient controls. PARDS was diagnosed and classified by severity according to Second Pediatric Acute Lung Injury Consensus Conference (PALICC-2) guidelines, based on oxygenation indices for non-invasive and invasive ventilation. Exclusion criteria included prior transplants, chronic lung disease, cyanotic congenital heart disease, prolonged ventilation, and other major conditions. After informed parental consent, 3 mL of peripheral venous blood was collected from all participants. Serum samples for apelin-13 and galectin-3 were stored at -80°C and analyzed using commercial enzyme-linked immunosorbent assay (ELISA) kits. Demographic, clinical, and laboratory data were systematically recorded for analysis.</p><p><strong>Results: </strong>The study and control groups were comparable in age and gender. Patients had significantly lower hemoglobin, hematocrit, red blood cell, calcium, and phosphorus levels, and higher neutrophil counts, C-reactive protein, and liver enzymes. Apelin-13 levels did not differ significantly between groups, wheras median galectin-3 levels were significantly higher in patients (p=0.003). Apelin-13 levels were significantly lower and galectin-3 levels significantly higher with increasing PARDS severity. Severe PARDS was associated with lower PaO2/FiO2 ratios, arterial pH, and higher ventilator pressures. Mortality was 36.4% in severe and 22.7% in moderate PARDS. Serum galectin-3 level was the sole independent predictor of mortality (OR: 1.20, 95% CI 1.02-1.39, p=0.02).</p><p><strong>Conclusion: </strong>Although the apelin/APJ system's role in acute lung injury is known, its diagnostic and prognostic value in PARDS requires further study. Galectin-3 levels correlate with disease severity and outcomes, highlighting the need for larger, age- and phenotype-homogenized studies to confirm its role as an independent mortality predictor.</p>","PeriodicalId":101314,"journal":{"name":"The Turkish journal of pediatrics","volume":"68 1","pages":"68-78"},"PeriodicalIF":0.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147505899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dose-specific childhood vaccine refusal in Balıkesir, Türkiye (2024): a population-based surveillance analysis.","authors":"Salih Keskin, Mithat Temizer","doi":"10.24953/turkjpediatr.2026.6792","DOIUrl":"10.24953/turkjpediatr.2026.6792","url":null,"abstract":"<p><strong>Background: </strong>Vaccine hesitancy has intensified since COVID-19. In Türkiye, a performance-based family medicine system provides free vaccines. Before May 2024, physicians could remove refusals from metrics tied to pay deductions, obscuring true rates. A new policy mandating documentation created a natural experiment. We used population-based data to quantify these previously hidden dose-specific refusal rates across the childhood schedule.</p><p><strong>Methods: </strong>We conducted a population-based ecological analysis of monthly dose-specific refusals among children aged 0-59 months in Balıkesir Province, in 2024. Refusals were extracted from Performance Exception Forms. Rates were calculated per 1,000 target children (Wilson 95% confidence intervals [CI]s), using populations derived from Turkish Statistical Institute counts. To quantify the policy's impact, we fitted an interrupted time-series regression with a fixed breakpoint at May 2024. This model estimated the baseline level and slope (January-April) and compared them to the immediate level shift and new monthly slope post-reform (May-December).</p><p><strong>Results: </strong>Of 3,584 missed-dose exceptions, 3,002 (83.8%) were refusals. The aggregate refusal rate was 3.9 per 1,000 (January-April) versus 21.6 per 1,000 (May-December), while the rate of on-schedule vaccinations decreased from 99.3% to 97.5%. Segmented regression indicated a baseline of 2.6 per 1,000 and a post-policy level increase of 13.7 per 1,000 (p=0.005); pre- and post-policy monthly slopes were not significant. Refusals concentrated in booster and later-scheduled doses (18-48 months), whereas primary-series doses showed lower, comparatively stable rates. Notably, refusal for the second measles-mumps-rubella dose (MMR-II, 48 months) rose toward year-end, reaching 47.4 per 1,000 in December (95% CI, 35.1-63.6).</p><p><strong>Conclusions: </strong>Mandatory documentation exposed substantial under-ascertainment of parental refusal in performance-based records. Refusal is disproportionately clustered at booster and later-childhood visits, with MMR-II approaching herd-immunity margins. Programmatically, pediatric booster encounters are key leverage points for targeted counseling, and sustained, transparent surveillance as enabled by the new policy, is essential for early signal detection and response.</p>","PeriodicalId":101314,"journal":{"name":"The Turkish journal of pediatrics","volume":"68 1","pages":"25-37"},"PeriodicalIF":0.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147505830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic nonbacterial osteomyelitis: current perspectives in pediatric practice.","authors":"Özge Başaran, Adalet Elçin Yıldız, Yelda Bilginer, Seza Özen","doi":"10.24953/turkjpediatr.2026.7367","DOIUrl":"10.24953/turkjpediatr.2026.7367","url":null,"abstract":"<p><p>Chronic nonbacterial osteomyelitis (CNO) is a rare, autoinflammatory bone disorder that predominantly affects children and adolescents. The disease covers a broad clinical spectrum ranging from isolated bone lesions to its severe multifocal form, chronic recurrent multifocal osteomyelitis (CRMO). Although its exact pathogenesis remains elusive, recent advances highlight a pivotal role of innate immune dysregulation, particularly involving imbalanced cytokine signaling. These abnormalities drive sterile bone inflammation and osteoclast activation, leading to bone pain and lytic or sclerotic lesions. CNO remains a diagnosis of exclusion owing to the lack of specific biomarkers or standardized diagnostic criteria; however, the recently developed European Alliance of Associations for Rheumatology/American College of Rheumatology (EULAR/ACR) classification framework represents an important step toward uniformity in research and clinical trials. Whole-body magnetic resonance imaging has emerged as the imaging modality of choice for diagnosis and monitoring, while biopsy is reserved for atypical or unifocal cases. Management is empirical and guided by disease severity, with nonsteroidal anti-inflammatory drugs as first-line therapy, followed by corticosteroids, disease-modifying antirheumatic drugs, bisphosphonates, and biologic agents such as tumor necrosis factor (TNF) inhibitors in refractory cases. New insights into the interleukin (IL)-1, IL-6, and IL-17/23 pathways have opened avenues for targeted therapies, including Janus kinase (JAK) inhibitors, in difficult-to-treat patients. Despite earlier perceptions of a benign course, long-term follow-up indicates a risk of relapses and structural complications, underscoring the need for early recognition and multidisciplinary management. Ongoing international collaborations are expected to refine diagnostic precision and optimize treatment strategies to improve outcomes in pediatric CNO.</p>","PeriodicalId":101314,"journal":{"name":"The Turkish journal of pediatrics","volume":"68 1","pages":"1-17"},"PeriodicalIF":0.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147505853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perianal and gluteal parasitic abscess of <i>Enterobius vermicularis</i>: case report and review of the literature.","authors":"Nazlı Gülsüm Akyel, Tuba Banaz, Burcu Arı Gökhan","doi":"10.24953/turkjpediatr.2025.6155","DOIUrl":"10.24953/turkjpediatr.2025.6155","url":null,"abstract":"<p><strong>Background: </strong>Enterobius vermicularis is a nematode that predominantly affects the pediatric population, particularly in families with school-aged children. While it typically causes intestinal symptoms, rare cases of extraintestinal involvement have been reported, including female genital tract involvement and complications such as appendicitis or enterocolitis. Perianal parasitic abscesses are also rare, with only a few cases reported in the literature.</p><p><strong>Case presentation: </strong>A 17-year-old female presented with abdominal pain during menstruation. Pelvic ultrasound revealed a septated cystic lesion located posterior to the uterus. Magnetic resonance imaging (MRI) demonstrated a perianal lesion with thick material, appearing iso- to hyperintense on both T1- and T2-weighted images. The lesion extended into the left gluteal muscles and showed peripheral contrast enhancement and diffusion restriction. Notably, there were no surrounding inflammatory changes, making an abscess diagnosis less likely. Surgical drainage revealed pus, and cytological analysis identified abundant parasitic oocytes consistent with E. vermicularis. The patient was treated with surgical drainage followed by pyrantel pamoate, resulting in near-complete resolution of the lesion at the one-month follow-up MRI. A literature review was also conducted to identify previously reported cases of parasitic abscesses and to explore the differential diagnoses of perianal cystic lesions.</p><p><strong>Conclusions: </strong>Perianal abscesses due to parasitic infections are rare, particularly those caused solely by E. vermicularis. Given the high prevalence in childhood infestations, parasitic abscesses should be considered in the differential diagnosis of perianal collections in pediatric patients, especially in the absence of peripheral inflammatory signs.</p>","PeriodicalId":101314,"journal":{"name":"The Turkish journal of pediatrics","volume":"68 1","pages":"143-149"},"PeriodicalIF":0.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147505893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}