发布求助
文献互助 智能选刊 最新文献

Zeitschrift für Immunit?tsforschung: Immunobiology最新文献

筛选
英文 中文
Characterization of the Serum Protein Inhibitor of the V.D.R.L. Test 血清蛋白抑制剂vdr试验的特点
Zeitschrift für Immunit?tsforschung: Immunobiology Pub Date : 1978-09-01 DOI: 10.1016/S0340-904X(78)80046-3
Gary H. Butler , L.J. Brenner
{"title":"Characterization of the Serum Protein Inhibitor of the V.D.R.L. Test","authors":"Gary H. Butler ,&nbsp;L.J. Brenner","doi":"10.1016/S0340-904X(78)80046-3","DOIUrl":"10.1016/S0340-904X(78)80046-3","url":null,"abstract":"<div><p>The V.D.R.L. test for syphilis was used to evaluate the ability of various serum protein fractions to inhibit cardiolipin flocculation tests for syphilis. Serum protein fractions obtained by modifications of the method of <span>Ecker</span> et al. (1) were chromatographed by DEAE or gel filtration and characterized by immunodiffusion and electrophoresis.</p><p>These experiments indicated that the V.D.R.L. inhibitor substance was in the IgM fraction of serum, although it has not yet been determined whether the inhibitor is an IgM antibody or another component which cofractionates with IgM.</p></div>","PeriodicalId":101288,"journal":{"name":"Zeitschrift für Immunit?tsforschung: Immunobiology","volume":"154 5","pages":"Pages 442-450"},"PeriodicalIF":0.0,"publicationDate":"1978-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0340-904X(78)80046-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79802654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inhibition of a Primary DNA-Synthesis Response by Trinitrobenzosulfonate (TNBS)-Activated Suppressor Cells; Characterization of the Inhibitory Cells 三硝基苯磺酸盐(TNBS)激活抑制细胞对dna合成反应的抑制作用抑制细胞的表征
Zeitschrift für Immunit?tsforschung: Immunobiology Pub Date : 1978-09-01 DOI: 10.1016/S0340-904X(78)80044-X
W. Suessmuth , W. Droege
{"title":"Inhibition of a Primary DNA-Synthesis Response by Trinitrobenzosulfonate (TNBS)-Activated Suppressor Cells; Characterization of the Inhibitory Cells","authors":"W. Suessmuth ,&nbsp;W. Droege","doi":"10.1016/S0340-904X(78)80044-X","DOIUrl":"10.1016/S0340-904X(78)80044-X","url":null,"abstract":"<div><p>Repeated intravenous injections of high doses of trinitrobenzosulfonate (TNBS) or dinitrobenzosulfonate (DNBS) activate suppressor cells which inhibit the <em>in vivo</em> activation of a primary DNA synthesis response against trinitroehlorobenzene (TNCB) and dinitrochlorobenzene (DNCB), respectively, almost completely and the delayed type hypersensitivity (DH) response only partially.</p><p>When tested on the DNA-synthesis response, the suppressor cells show excellent specificity with little cross reactivity of TNBS (or DNBS) induced suppressor cells for DNCB- (or TNCB-) specific responses. TNBS- and DNBS-specific suppressor activity is found in spleen cells, mesenteric lymph nodes and peripheral lymph nodes. The activation of suppressor cells is resistant to the early effects of adult thymectomy (ATx), but sensitive to pretreatment with cyclophosphamide (CyP).</p><p>The suppressor cells are not simply haptenated cells. They need several days for their activation and are inactivated by incubation for 30 minutes at 56°C or by 2,000 R irradiation.</p><p>Attempts to obtain soluble suppressor factors by in vitro incubation or extraction of these suppressor cells failed.</p></div>","PeriodicalId":101288,"journal":{"name":"Zeitschrift für Immunit?tsforschung: Immunobiology","volume":"154 5","pages":"Pages 416-432"},"PeriodicalIF":0.0,"publicationDate":"1978-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0340-904X(78)80044-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85880890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of Peripheral B and T Lymphocytes in Piglets 仔猪外周血B淋巴细胞和T淋巴细胞的发育
Zeitschrift für Immunit?tsforschung: Immunobiology Pub Date : 1978-09-01 DOI: 10.1016/S0340-904X(78)80043-8
Cristina Reyero , Johann G. Thalhammer, Gerhard Reszler, Wilhelm Stöckl
{"title":"Development of Peripheral B and T Lymphocytes in Piglets","authors":"Cristina Reyero ,&nbsp;Johann G. Thalhammer,&nbsp;Gerhard Reszler,&nbsp;Wilhelm Stöckl","doi":"10.1016/S0340-904X(78)80043-8","DOIUrl":"10.1016/S0340-904X(78)80043-8","url":null,"abstract":"<div><p>The percentage of B and T lymphocytes in the peripheral blood of piglets during their first 35 days of life was estimated by means of the immunofluorescence-labelled anti-L chains sera and the spontaneous E-rosette techniques.</p><p>The mean values obtained for adult pigs PBL were 23.8 ± 10.2% of B and 38.0 ± 8.4% of T lymphocytes. The piglets showed a linear increase for the B lymphocytes starting from a mean value of 4% observed for the newborns. The trend of the T lymphocytes was represented by a bimodal curve. It starts for newborns at 3% and shows a change in shape by the 10th day. It is suggested that the piglets have adult levels of B and T lymphocytes by the time of weaning.</p></div>","PeriodicalId":101288,"journal":{"name":"Zeitschrift für Immunit?tsforschung: Immunobiology","volume":"154 5","pages":"Pages 409-415"},"PeriodicalIF":0.0,"publicationDate":"1978-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0340-904X(78)80043-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73727995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Promotion of L1210 Tumour Growth by Macrophages 巨噬细胞促进L1210肿瘤生长
Zeitschrift für Immunit?tsforschung: Immunobiology Pub Date : 1978-09-01 DOI: 10.1016/S0340-904X(78)80045-1
R.P. Huget, H.-D. Flad , H.G. Opitz
{"title":"Promotion of L1210 Tumour Growth by Macrophages","authors":"R.P. Huget,&nbsp;H.-D. Flad ,&nbsp;H.G. Opitz","doi":"10.1016/S0340-904X(78)80045-1","DOIUrl":"10.1016/S0340-904X(78)80045-1","url":null,"abstract":"<div><p>Low numbers (10<sup>4</sup>) of peritoneal exudate L1210 mouse lymphoma cells were injected into DBA/2 mice subcutaneously and the development of tumours was followed. Tumour takes occurred in 100% of the animals within 9 days after tumour transplantation. The latent period of tumour development was prolonged by 6–10 days when tumour cells of the peritoneal exudate, depleted of adherent/phagocytic cells, were used in the inoculum or when tumour cells derived from continuous cell cultures were used. Addition of adherent cells in high numbers to in-vitro-derived L1210 cells accelerated tumour growth. This effect was found to be not specific for adherent/phagocytic cells, as liver cells had the same influence on tumour growth. It is concluded that, under certain experimental conditions, a cell population with the functional properties of macrophages is able to promote tumour development, most likely due to their non-specific effect on the micro-environment of the growing tumour.</p></div>","PeriodicalId":101288,"journal":{"name":"Zeitschrift für Immunit?tsforschung: Immunobiology","volume":"154 5","pages":"Pages 433-441"},"PeriodicalIF":0.0,"publicationDate":"1978-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0340-904X(78)80045-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73775465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Cell-mediated Immunity in Response to HBs Antigen HBs抗原应答的细胞介导免疫
Zeitschrift für Immunit?tsforschung: Immunobiology Pub Date : 1978-09-01 DOI: 10.1016/S0340-904X(78)80048-7
Andrzej Szkaradkiewicz , Witold Kiczka
{"title":"Cell-mediated Immunity in Response to HBs Antigen","authors":"Andrzej Szkaradkiewicz ,&nbsp;Witold Kiczka","doi":"10.1016/S0340-904X(78)80048-7","DOIUrl":"10.1016/S0340-904X(78)80048-7","url":null,"abstract":"<div><p>The response of peripheral blood leukocytes to purified HB<sub>s</sub>Ag was studied in vitro by means of the leukocyte migration test in patients with acute viral hepatitis B, patients with chronic aggressive hepatitis carrying HB<sub>s</sub>Ag, and in asymptomatic carriers of HB<sub>s</sub> antigen. In the acute period of the disease no leukocyte migration inhibition could be observed. Patients with chronic aggressive hepatitis also frequently failed to develop cell-mediated immunity to HB<sub>s</sub>Ag. Results obtained for HB<sub>s</sub> antigen carriers did not differ from those of normal blood donors. The observations may indicate participation of cell-mediated immunity in the development of liver damage.</p></div>","PeriodicalId":101288,"journal":{"name":"Zeitschrift für Immunit?tsforschung: Immunobiology","volume":"154 5","pages":"Pages 463-470"},"PeriodicalIF":0.0,"publicationDate":"1978-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0340-904X(78)80048-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87764563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Effect of Human Immunoglobulin Preparations on Fc Rosette Formation between Anti-D-Coated Erythrocytes and Lymphocytes 人免疫球蛋白制剂对抗d包被红细胞和淋巴细胞间Fc莲座形成的影响
Zeitschrift für Immunit?tsforschung: Immunobiology Pub Date : 1978-06-01 DOI: 10.1016/S0340-904X(78)80011-6
H. Ishiyama , K. Okuyama, K. Masuda, J. Yasuda
{"title":"Effect of Human Immunoglobulin Preparations on Fc Rosette Formation between Anti-D-Coated Erythrocytes and Lymphocytes","authors":"H. Ishiyama ,&nbsp;K. Okuyama,&nbsp;K. Masuda,&nbsp;J. Yasuda","doi":"10.1016/S0340-904X(78)80011-6","DOIUrl":"10.1016/S0340-904X(78)80011-6","url":null,"abstract":"<div><p>Human immunoglobulin (Ig) preparations were tested for their inhibitory effect on Fc rosette formation between anti-D-coated human erythrocytes and lymphocytes, as compared to their complement activating capacity. Both of the two biological activities ascribed to the sites in the Fc portion of the IgG molecules were found to be reduced in the pepsin-treated, as well as in the S-sulfonated Ig preparations, as compared to the activities of the normal human Ig preparation. In the plasmin-treated Ig preparation, which was found to be composed of three major components: plasmin-Fab, plasmin-Fc and plasminresistant IgG, the activity of inhibiting the Fc rosette formation was well retained, in contrast to its low complement activating capacity.</p></div>","PeriodicalId":101288,"journal":{"name":"Zeitschrift für Immunit?tsforschung: Immunobiology","volume":"154 4","pages":"Pages 387-398"},"PeriodicalIF":0.0,"publicationDate":"1978-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0340-904X(78)80011-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73831955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Quantification of Turkey Immunoglobulins IgA, IgM and IgG in Serum and Secretions 火鸡血清和分泌物中免疫球蛋白IgA、IgM和IgG的定量测定
Zeitschrift für Immunit?tsforschung: Immunobiology Pub Date : 1978-06-01 DOI: 10.1016/S0340-904X(78)80019-0
J. Goudswaard , A. Noordzij, R.H. van Dam, J.A. van der Donk
{"title":"Quantification of Turkey Immunoglobulins IgA, IgM and IgG in Serum and Secretions","authors":"J. Goudswaard ,&nbsp;A. Noordzij,&nbsp;R.H. van Dam,&nbsp;J.A. van der Donk","doi":"10.1016/S0340-904X(78)80019-0","DOIUrl":"10.1016/S0340-904X(78)80019-0","url":null,"abstract":"<div><p>The immunoglobulins IgA, IgM and IgG of the turkey were quantitated in individual serum samples as well as in pooled sera. The variability of Ig levels in normal, healthy birds was quite high: IgA: mean value 0.633 mg/ml (4.0 x-2.5 x); IgM: mean value 4.37 mg/ml (0.5 x-1.4 x) and IgG: mean value 8.92 mg/ml (0.6 x-1.7 x).</p><p>Immunoglobulin levels in egg-yolk, egg-white, bile and some intraocular tissues were quantitated as well. An interesting finding was, that the forementioned variability was by far not so high with respect to IgG levels in 20 egg-yolk samples: mean value 5.1 mg/ml (0.86 x-1.17 x). Though IgG and IgM could be detected in pooled turkey bile, IgA predominated in this secretion. In aqueous humor, iris tissue and vitreous body only IgG could be detected.</p></div>","PeriodicalId":101288,"journal":{"name":"Zeitschrift für Immunit?tsforschung: Immunobiology","volume":"154 3","pages":"Pages 248-255"},"PeriodicalIF":0.0,"publicationDate":"1978-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0340-904X(78)80019-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79871259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Haptoglobins are Antibody-like Proteins 触珠蛋白是类抗体蛋白
Zeitschrift für Immunit?tsforschung: Immunobiology Pub Date : 1978-06-01 DOI: 10.1016/S0340-904X(78)80013-X
O. Prokop , W. Köhler
{"title":"Haptoglobins are Antibody-like Proteins","authors":"O. Prokop ,&nbsp;W. Köhler","doi":"10.1016/S0340-904X(78)80013-X","DOIUrl":"10.1016/S0340-904X(78)80013-X","url":null,"abstract":"","PeriodicalId":101288,"journal":{"name":"Zeitschrift für Immunit?tsforschung: Immunobiology","volume":"154 4","pages":"Pages 407-408"},"PeriodicalIF":0.0,"publicationDate":"1978-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0340-904X(78)80013-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87137263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Surface Carbohydrate Composition of Murine Thymocytes and of Lymph Node Cells from Normal and Athymic (Nude) Mice 小鼠胸腺细胞和正常及裸小鼠淋巴结细胞的表面碳水化合物组成
Zeitschrift für Immunit?tsforschung: Immunobiology Pub Date : 1978-06-01 DOI: 10.1016/S0340-904X(78)80018-9
Wulf Droege , Prem Pal Singh , Otto Lüderitz
{"title":"Surface Carbohydrate Composition of Murine Thymocytes and of Lymph Node Cells from Normal and Athymic (Nude) Mice","authors":"Wulf Droege ,&nbsp;Prem Pal Singh ,&nbsp;Otto Lüderitz","doi":"10.1016/S0340-904X(78)80018-9","DOIUrl":"10.1016/S0340-904X(78)80018-9","url":null,"abstract":"<div><p>Surface glycoproteins (papain digests) have been isolated from lymph node cells of normal mice which contain mainly T cells, and from lymph node cells of nude (athymic) mice, which essentially represent B cells. Gaschromatographic analysis revealed that the glycoproteins from the lymph node cells of the euthymic mice contain less galactose than the glycoproteins from lymph node cells of the athymic mice, but contain still more galactose than glycoproteins from thymocytes. Lymph node cells from both sources contain about equal amounts of neuraminic acid, while thymocytes contain slightly less sialic acid. The observed differences provide a molecular explanation for the different reactivity of murine B cells and T cells towards soybean agglutinine and other galactose-binding plant lectins.</p></div>","PeriodicalId":101288,"journal":{"name":"Zeitschrift für Immunit?tsforschung: Immunobiology","volume":"154 3","pages":"Pages 243-247"},"PeriodicalIF":0.0,"publicationDate":"1978-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0340-904X(78)80018-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90174772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genetics of the Idiotype of Strain AKR Antibodies to Group A Streptococcal Carbohydrate; further Evidence for a Low Degree of Homology in the VH Chromosomal Region A组链球菌碳水化合物AKR抗体独特型的遗传研究VH染色体区域低同源性的进一步证据
Zeitschrift für Immunit?tsforschung: Immunobiology Pub Date : 1978-06-01 DOI: 10.1016/S0340-904X(78)80022-0
P. Krammer , B.A. Taylor , K. Eichmann
{"title":"Genetics of the Idiotype of Strain AKR Antibodies to Group A Streptococcal Carbohydrate; further Evidence for a Low Degree of Homology in the VH Chromosomal Region","authors":"P. Krammer ,&nbsp;B.A. Taylor ,&nbsp;K. Eichmann","doi":"10.1016/S0340-904X(78)80022-0","DOIUrl":"10.1016/S0340-904X(78)80022-0","url":null,"abstract":"<div><p>A new V<sub>H</sub>gene is described which governs the expression of idiotypes associated with the antibody response of strain AKR mice to Group A streptococcal carbohydrate (A-CHO). This V<sub>H</sub> gene, termed ACH<sup>d</sup>, is identified using guinea pig antisera to a pool of strain AKR antibodies to A-CHO. The genetic polymorphism is revealed by quantitative differences in idiotype expression between different inbred strains. In recombinant inbred strains linkage to the Ig-l<sup>d</sup> allotype allele of strain AKR is demonstrated. In a putative recombinant strain it appears that ACH<sup>d</sup> maps at a locus different from that of A5A<sup>+</sup>, another V<sub>H</sub> gene controlling idiotypes of anti-A-CHO antibodies. This represents a further example of pseudoallelism between related Vh genes and lack of homology in the V<sub>H</sub> chromosomal region. Expression of the ACH<sup>d</sup> gene was independent of the Ly-2,3 locus which is associated with kappa chain variants.</p></div>","PeriodicalId":101288,"journal":{"name":"Zeitschrift für Immunit?tsforschung: Immunobiology","volume":"154 3","pages":"Pages 284-294"},"PeriodicalIF":0.0,"publicationDate":"1978-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0340-904X(78)80022-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91429085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信