Zeitschrift für Immunit?tsforschung: Immunobiology最新文献_第10页

No Development of Experimental Autoimmune Thyroiditis in Nude Mice 裸鼠未发生实验性自身免疫性甲状腺炎

Zeitschrift für Immunit?tsforschung: Immunobiology Pub Date : 1978-03-01 DOI: 10.1016/S0340-904X(78)80031-1

G. Wick , S. Schwarz, P.U. Müller

引用次数: 5

Zeitschrift für Immunit?tsforschung: Immunobiology Pub Date : 1978-03-01 DOI: 10.1016/S0340-904X(78)80035-9

K. Fedeblin

引用次数: 0

Carbohydrate Composition of Peripheral, Cultured and Leukaemic Human Lymphocyte Plasma Membranes 外周、培养和白血病人淋巴细胞膜的碳水化合物组成

Zeitschrift für Immunit?tsforschung: Immunobiology Pub Date : 1978-03-01 DOI: 10.1016/S0340-904X(78)80034-7

R.A. Newman, W.M. Glöckner, G. Uhlenbruck

{"title":"Carbohydrate Composition of Peripheral, Cultured and Leukaemic Human Lymphocyte Plasma Membranes","authors":"R.A. Newman, W.M. Glöckner, G. Uhlenbruck","doi":"10.1016/S0340-904X(78)80034-7","DOIUrl":"10.1016/S0340-904X(78)80034-7","url":null,"abstract":"<div><p>Plasma membranes isolated from peripheral blood lymphocytes of normal donors, lymphocytes from patients with chronic lymphatic leukaemia (CLL), a T cell and B cell line (MOLT-3 and RPMI-1788) were analysed and compared for total carbohydrate contents. T cells and peripheral blood lymphocytes contained the highest relative amounts of sialic acid and fucose, whereas chronic lymphatic leukaemic cells possessed the highest amounts of N-acetylgalactosamine and also more total cell surface carbohydrate.</p><p>The Thomsen-Friedenreieh antigen (T<sub>F</sub>) was detected serologically on membrane fractions by the use of anti-T<sub>F</sub> containing sera and specific lectins from <em>Arachis hypogaea, Agaricus bisporus</em> and <em>Vicia graminea</em>. The disaccharide ß-D-galactosyl(1-3)-N-acetyl-D-galactosamine is the immunodominant carbohydrate group of the T<sub>F</sub> antigen and was detected as its reduced form, by gas chromatography, in all cells, thus correlating serological and analytical evidence. The haemagglutinating activity of the lectins and sera used was only inhibited by plasma membranes after the removal of sialic acid showing that the native form of this antigen is normally masked by sialic acid in CLL cells as well as normal lymphocytes.</p></div>","PeriodicalId":101288,"journal":{"name":"Zeitschrift für Immunit?tsforschung: Immunobiology","volume":"154 2","pages":"Pages 186-194"},"PeriodicalIF":0.0,"publicationDate":"1978-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0340-904X(78)80034-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88039101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Chemotactic Activity of Lectins in vitro 凝集素体外趋化活性研究

Zeitschrift für Immunit?tsforschung: Immunobiology Pub Date : 1978-03-01 DOI: 10.1016/S0340-904X(78)80033-5

Gerd Till , Volker Lenhard, Diethard Gemsa

引用次数: 5

Immunological Studies of HSV-Infection of Resistant and Susceptible Inbred Strains of Mice 耐药和易感小鼠近交系感染单纯疱疹病毒的免疫学研究

Zeitschrift für Immunit?tsforschung: Immunobiology Pub Date : 1978-03-01 DOI: 10.1016/S0340-904X(78)80029-3

Holger Kirchner , Mosze Kochen, Hans Martin Hirt, Klaus Munk

{"title":"Immunological Studies of HSV-Infection of Resistant and Susceptible Inbred Strains of Mice","authors":"Holger Kirchner , Mosze Kochen, Hans Martin Hirt, Klaus Munk","doi":"10.1016/S0340-904X(78)80029-3","DOIUrl":"10.1016/S0340-904X(78)80029-3","url":null,"abstract":"<div><p>DBA/2 mice were found to be quite susceptible to infection with herpes simplex virus (HSV) while C57BL/6 mice and F1 hybrids between the 2 strains were relatively resistant. This difference was most marked after ip infection, but could also be demonstrated after intracerebral, intravenous or subcutaneous infection. In both strains the LD<sub>50</sub> was considerably higher after ip infection than after iv infection, and a dose of X-irradiation was required to kill the mice by sc infection. A/J and BALB/c mice were equally susceptible after ip infection but differed significantly after iv infection. C57BL/6 were made susceptible to ip infection by immunosuppression with antilymphocyte serum or cyclophosphamide. LPS, when given simultaneously with HSV also markedly increased the susceptibility of C57BL/6 mice. Susceptible DBA/2 mice which survived a low dose of HSV ip were not immune but C57BL/6 mice surviving a high dose were immune against rechallenge. Both strains of mice could be protected by an apathogenic, tissue-culture-attenuated strain of HSV against infection with the virulent strain. They could also be protected by iv injection of a sublethal dose against a lethal ip infection.</p></div>","PeriodicalId":101288,"journal":{"name":"Zeitschrift für Immunit?tsforschung: Immunobiology","volume":"154 2","pages":"Pages 147-154"},"PeriodicalIF":0.0,"publicationDate":"1978-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0340-904X(78)80029-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90406286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 32

Antigenic Difference between Serum Amyloid Protein SAA and its Low Molecular Weight Derivative SAAL Revealed by an Anti-Amyloid A Antiserum at Different Temperatures1 不同温度下血清淀粉样蛋白SAA及其低分子量衍生物SAAL的抗原性差异

Zeitschrift für Immunit?tsforschung: Immunobiology Pub Date : 1978-03-01 DOI: 10.1016/S0340-904X(78)80032-3

Reinhold P. Linke

引用次数: 4

Human Blood Lymphocyte Fractionation with Special Attention to their Cytotoxic Potential 人血液淋巴细胞的分离，特别注意它们的细胞毒性潜能

Zeitschrift für Immunit?tsforschung: Immunobiology Pub Date : 1978-03-01 DOI: 10.1016/S0340-904X(78)80027-X

T. Bakács, E. Klein , E. Yefenof, P. Gergely , M. Steinitz

{"title":"Human Blood Lymphocyte Fractionation with Special Attention to their Cytotoxic Potential","authors":"T. Bakács, E. Klein , E. Yefenof, P. Gergely , M. Steinitz","doi":"10.1016/S0340-904X(78)80027-X","DOIUrl":"10.1016/S0340-904X(78)80027-X","url":null,"abstract":"<div><p>In studies concerning the natural cytotoxic activity of human blood lymphocytes we have found that: 1. T cells, which rosette with sheep erythrocytes can be separated by centrifuging on Ficoll the lymphocyte and erythrocyte mixture without previously pelleting and incubating in the cold. 2. Lysis of marker erythrocytes with ammonium chloride impairs the cytotoxic activity of lymphocytes. Incubation at 37 °C for 12 hr prior to the test restores the activity to some extent. 3. A high proportion of the so called «null» fraction i.e. cells remaining in the interface after removal of B cells (passage on nylon column) and sedimentation of E rosettes, sediments as rosettes with sheep EAC'indicating that these cells carry low density E and C<sub>3</sub> receptors. Rosetting with SRBC or ox EAC' gave significantly lower values.</p><p>On a per cell basis the «null» fraction was the most efficient one in natural cytotoxicity. Depletion of cells with low affinity E or E and C<sub>3</sub> receptors left highly active subfractions.</p></div>","PeriodicalId":101288,"journal":{"name":"Zeitschrift für Immunit?tsforschung: Immunobiology","volume":"154 2","pages":"Pages 121-134"},"PeriodicalIF":0.0,"publicationDate":"1978-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0340-904X(78)80027-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86856380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 14

Hemagglutinins in Female Fish Gonads: Comparative Investigations on Perch (Perca fluviatilis) Gonads of Different Stages of Development 雌鱼性腺中的血凝素:不同发育阶段鲈鱼性腺的比较研究

Zeitschrift für Immunit?tsforschung: Immunobiology Pub Date : 1978-03-01 DOI: 10.1016/S0340-904X(78)80030-X

H. Schenkel-Brunner , H. Kothbauer

引用次数: 1

Idiotypes, Subject and Object of Immunologieal Research 免疫学研究的独特型、主体和客体

Zeitschrift für Immunit?tsforschung: Immunobiology Pub Date : 1978-03-01 DOI: 10.1016/S0340-904X(78)80024-4

K. Eichmann

引用次数: 0

Zeitschrift für Immunit?tsforschung: Immunobiology Pub Date : 1978-03-01 DOI: 10.1016/S0340-904X(78)80036-0

K.E. Schneweis

引用次数: 0