Tetrahedron Green Chem最新文献_第2页

Green and traditional one-pot synthesis techniques for bioactive quinoline derivatives: A review

Tetrahedron Green Chem Pub Date : 2025-01-02 DOI: 10.1016/j.tgchem.2025.100062

Manav C. Parmar, Bonny Y. Patel

{"title":"Green and traditional one-pot synthesis techniques for bioactive quinoline derivatives: A review","authors":"Manav C. Parmar, Bonny Y. Patel","doi":"10.1016/j.tgchem.2025.100062","DOIUrl":"10.1016/j.tgchem.2025.100062","url":null,"abstract":"<div><div>The review examines one-pot strategies and their mechanistic approaches for synthesizing the quinoline nucleus from 2009 to 2024, with a focus on their therapeutic potential. The paradigm shifts from conventional synthetic protocols to advanced green methodologies has revolutionized the synthesis of quinoline derivatives. Strategies that adhere to sustainable chemistry principles by minimizing waste, solvent consumption, and energy input. Various green catalysts, including p-toluenesulfonic acid (p-TSA), para-sulfonic acid calix[4]arene (CX4SO3H), cerium nitrate, ammonium acetate, potassium carbonate (K2CO3), and catalyst-free techniques, have proven effective in synthesizing quinoline analogs. The use of greener solvents such as ethanol and water further supports the eco-friendly synthesis of these compounds. The review also highlights a broad spectrum of pharmacological activities of quinoline derivatives, including antibacterial, antiviral, antidiabetic, anticancer properties and so on. SAR studies show that adding EDGs (-CH3, –OCH3, –OH) and EWGs (-Cl, –F, –NO2, –CF3) can enhance electronic properties, lipophilicity, and receptor-binding affinities. Moreover, hybridization with heterocyclic scaffolds such as furan, pyrazole, indole, and thiadiazole significantly improves bioactivity, demonstrating the intricate relationship between structural modifications and biological efficacy. By merging sustainable chemistry with targeted pharmacological strategies, quinoline-based compounds emerge as innovative candidates for diverse clinical applications.</div></div>","PeriodicalId":101215,"journal":{"name":"Tetrahedron Green Chem","volume":"5 ","pages":"Article 100062"},"PeriodicalIF":0.0,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143135611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Solvent-free and eco-friendly green protocol for N-Boc Protection of amines using picric acid as a catalyst

Tetrahedron Green Chem Pub Date : 2024-12-13 DOI: 10.1016/j.tgchem.2024.100061

Ramesha Thongolla , Ummareddy Venkata Subba Reddy , Sailam Sri Gogula , Empati Raja Sekhar , Puchakayala Muralidhar Reddy , Anren Hu

引用次数: 0

ANO-catalyzed multicomponent synthesis of 3-nitroalkyl-N-substituted pyrroles

Tetrahedron Green Chem Pub Date : 2024-12-08 DOI: 10.1016/j.tgchem.2024.100060

Luiz H. Dapper , Viviane T. Mena , Márcio S. Silva , Filipe Penteado , Eder J. Lenardão

引用次数: 0

An efficient photo-degradation of methylene blue by poly-3-thenoic acid sensitized Co/TiO2 under visible light and inactivation of pathogens

Tetrahedron Green Chem Pub Date : 2024-12-04 DOI: 10.1016/j.tgchem.2024.100058

Neha Kumari , Sudhakar Chintakula , Immandhi Sai Sonali Anantha , Pilla Pushpavati , Suresh Maddila

{"title":"An efficient photo-degradation of methylene blue by poly-3-thenoic acid sensitized Co/TiO2 under visible light and inactivation of pathogens","authors":"Neha Kumari , Sudhakar Chintakula , Immandhi Sai Sonali Anantha , Pilla Pushpavati , Suresh Maddila","doi":"10.1016/j.tgchem.2024.100058","DOIUrl":"10.1016/j.tgchem.2024.100058","url":null,"abstract":"<div><div>Methylene blue dye is used extensively in industries, including paper, temporary hair coloring, coating for paper stock wool, and cotton dying. When the amount of methylene blue dye is more significant than 2 mg/kg, it can lead to serious health issues in people, including cyanosis, tissue necrosis, elevated heart rate, vomiting, shock, and Heinz body formation. The present chapter discusses the sol-gel-assisted synthesis of P3TA-supported Cobalt-doped TiO2 nanohybrid. This study investigated the characteristics of both prepared bare TiO2 and metal (Co) doped nano-hybrid using a variety of analytical tools, including XRD, SEM-EDX, BET, FTIR, XPS, and UV–visible DRS. The photo-catalytic performance of prepared samples was executed towards the degradation of methylene blue (MB) dye under visible light irradiations. Additionally, tests for antibiotic resistance were performed on the pathogens E. coli and S. aureus. Significant antibacterial activities against E. coli and S. aureus were demonstrated by the chemical under investigation (P3TA/Co-TiO2) at a higher dosage of 800 μg/mL, with inhibition zones of 2.0 mm and 2.1 mm, respectively. The antibacterial activity against E. coli and S. aureus at 400 μg/mL was negligible, with inhibition zones of 1.0 mm and 1.2 mm, respectively. Because these materials are affordable and adaptable, they further the field of nano photo-catalysts.</div></div>","PeriodicalId":101215,"journal":{"name":"Tetrahedron Green Chem","volume":"5 ","pages":"Article 100058"},"PeriodicalIF":0.0,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143135612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparing the photocatalytic activity of suspended and floating Ag-decorated TiO2 for dye removal

Tetrahedron Green Chem Pub Date : 2024-12-04 DOI: 10.1016/j.tgchem.2024.100059

Nila Davari , Ermelinda Falletta , Claudia L. Bianchi , Viviane Yargeau , Cristina Rodriguez-Seco , Daria C. Boffito

{"title":"Comparing the photocatalytic activity of suspended and floating Ag-decorated TiO2 for dye removal","authors":"Nila Davari , Ermelinda Falletta , Claudia L. Bianchi , Viviane Yargeau , Cristina Rodriguez-Seco , Daria C. Boffito","doi":"10.1016/j.tgchem.2024.100059","DOIUrl":"10.1016/j.tgchem.2024.100059","url":null,"abstract":"<div><div>We proposed a two-step synthesis process to fabricate floating TiO2 and Ag-decorated TiO2 (Ag/TiO2) photocatalysts. In the first step, an ultrasound-assisted sol-gel method followed by spray drying was adopted to synthesize powder photocatalysts. Next, the powder samples were immobilized onto a floating polyurethane foam (PUF) support with an ultrasound-assisted impregnation method. The photocatalytic activity of TiO2 and Ag/TiO2 was evaluated to remove methyl orange (MO) as a dye pollutant in two suspended and floating photocatalytic systems. Ag decoration on TiO2 improved the optical and textural properties by narrowing the bandgap energy to 2.9 eV and increasing the surface area from 10 m2/g to 30 m2/g. Ag/TiO2 exhibited higher photocatalytic activity compared to TiO2 for MO removal, which was 98 % for suspended and 95 % for floating catalysts under simulated sunlight irradiation. In addition, floating photocatalysts exhibited higher photocatalytic activity over five cycles of reuse. Floating Ag/TiO2@PUF maintained 89 % of its initial photoactivity, while suspended Ag/TiO2 lost 50 % after the five cycles. Moreover, we investigated the effect of operating conditions on the photocatalytic performance of floating Ag/TiO2@PUF. Optimal conditions for the complete removal of MO below detection limits were obtained as follows: Ag/TiO2@PUF loading = 0.4:200 g/mL, initial MO concentration = 5 mg/L, time = 90 min, and pH = 4 under simulated sunlight irradiation. This study highlights the potential of floating photocatalyst systems as a sustainable, reusable, and scalable approach for wastewater treatment, addressing challenges in catalyst recovery and efficiency under real-world conditions.</div></div>","PeriodicalId":101215,"journal":{"name":"Tetrahedron Green Chem","volume":"5 ","pages":"Article 100059"},"PeriodicalIF":0.0,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143096513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synergistic effects of hydroxyl and tertiary amine in the catalytic carbonatization of epoxides with CO2 at atmospheric pressure 羟基和叔胺在常压下催化环氧化物与二氧化碳的碳化反应中的协同效应

Tetrahedron Green Chem Pub Date : 2024-11-08 DOI: 10.1016/j.tgchem.2024.100057

Fawaz Al Hussein , Andreas Hartwig , Henning Großekappenberg

{"title":"Synergistic effects of hydroxyl and tertiary amine in the catalytic carbonatization of epoxides with CO2 at atmospheric pressure","authors":"Fawaz Al Hussein , Andreas Hartwig , Henning Großekappenberg","doi":"10.1016/j.tgchem.2024.100057","DOIUrl":"10.1016/j.tgchem.2024.100057","url":null,"abstract":"<div><div>Fixation of carbon dioxide is a key issue for the sustainable synthesis of chemical compounds. A catalyst system for the preparation of cyclic carbonates by the fixation of carbon dioxide (CO2) onto epoxides is presented. This system is designed for easy application due to the availability of the compounds on an industrial scale as well as moderate reaction conditions. Notably, it avoids the use of metal-halogen catalysts and instead employs a tertiary amine as the catalytic center, in conjunction with an alcohol acting as a hydrogen bond donor (HBD). The kinetics of the cycloaddition reaction between epoxides and CO2 were thoroughly investigated using IR spectroscopy. Remarkably, optimization of the amino-to-alcohol group ratio and the amine structure was carried out to enhance the overall performance of the catalyst system showing a synergistic effect between the tertiary amine and the hydroxyl. Most notably, this entire process is conducted without the use of solvents and operates at ambient pressure, underscoring its significant ecological advantages.</div></div>","PeriodicalId":101215,"journal":{"name":"Tetrahedron Green Chem","volume":"4 ","pages":"Article 100057"},"PeriodicalIF":0.0,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142655451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Three-component carbonylative Michael addition of aryl bromides using abundant metal-carbonyl under light 在光照下利用丰富的金属羰基对芳基溴进行三组分羰基迈克尔加成反应

Tetrahedron Green Chem Pub Date : 2024-10-02 DOI: 10.1016/j.tgchem.2024.100056

Shiqian Zhang , Quansheng Mou , Bowen Cao, Tongyu Han, Mingxin Liu

引用次数: 0

Solvent-free microwave reactions towards significant organic transformations: A green approach 实现重大有机转化的无溶剂微波反应：绿色方法

Tetrahedron Green Chem Pub Date : 2024-09-13 DOI: 10.1016/j.tgchem.2024.100054

Animesh Mondal , Chhanda Mukhopadhyay

引用次数: 0

Egg shell powder mediated Cu catalyst: A biowaste based catalytic approach for the synthesis of quinazolin-4(3H)-ones and propargyl amines 蛋壳粉介导的铜催化剂：基于生物废料的喹唑啉-4(3H)-酮和丙炔胺合成催化方法

Tetrahedron Green Chem Pub Date : 2024-09-11 DOI: 10.1016/j.tgchem.2024.100055

Nilakshi Dutta , Kaberi Hazarika , Roktopol Hazarika , Bulan B. Boruah , Surajit Konwer , Bipul Sarma , Diganta Sarma

{"title":"Egg shell powder mediated Cu catalyst: A biowaste based catalytic approach for the synthesis of quinazolin-4(3H)-ones and propargyl amines","authors":"Nilakshi Dutta , Kaberi Hazarika , Roktopol Hazarika , Bulan B. Boruah , Surajit Konwer , Bipul Sarma , Diganta Sarma","doi":"10.1016/j.tgchem.2024.100055","DOIUrl":"10.1016/j.tgchem.2024.100055","url":null,"abstract":"<div>A novel and efficient approach for a tandem oxidative synthesis of quinazolin-4(3H)-one from 2-aminobenzonitrile and benzyl alcohol has been unveiled via Cu2(CO3)(OH)2. Herein CuSO4.5H2O accompanied by egg shell powder is used for the easy preparation of Cu2(CO3)(OH)2. The reported method portrays a wide range of substrate scope with good to excellent yield and the given reaction proceed at room temperature within 12 h. Single crystal of one of the synthesized quinazolin-4(3H)-ones was analysed through single crystal X-ray diffraction (SC-XRD). Some of the compounds reported here are also known to possess various pharmaceutical activities. Eventually the newly prepared catalyst was applied for propargylamine synthesis via a multi component reaction. Perceiving all the advantages, present protocol is conceivably considered as clean, cost-effective and sustainable over reported procedures used for synthesis of quinazolin-4(3H)-ones and propargyl amines.</div>","PeriodicalId":101215,"journal":{"name":"Tetrahedron Green Chem","volume":"4 ","pages":"Article 100055"},"PeriodicalIF":0.0,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773223124000207/pdfft?md5=c9c788110c513235d50753ee01d75177&pid=1-s2.0-S2773223124000207-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142232338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Photocatalysed eosin Y mediated synthesis of biologically potent 4 (3H)-quinazolinone 光催化曙红 Y 介导的生物活性 4 (3H) - 喹唑啉酮的合成

Tetrahedron Green Chem Pub Date : 2024-09-02 DOI: 10.1016/j.tgchem.2024.100053

Pravin Kumar Singh , Rohit Kumar , Vishal Srivastava , Praveen Pratap Singh

引用次数: 0