Revue Fran?aise des Laboratoires最新文献

{"title":"PCU : analyse automatique des acides aminés","authors":"","doi":"10.1016/S0338-9898(05)80206-9","DOIUrl":"https://doi.org/10.1016/S0338-9898(05)80206-9","url":null,"abstract":"","PeriodicalId":101129,"journal":{"name":"Revue Fran?aise des Laboratoires","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2005-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0338-9898(05)80206-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91638882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Formation de médecins aux techniques de laboratoire avant un départ en zone tropicale","authors":"Éric Garnotel ,&nbsp;Pierre Hance ,&nbsp;Jean-Jacques De Pina ,&nbsp;Pierre Nicolas ,&nbsp;Marc Morillon","doi":"10.1016/S0338-9898(05)80200-8","DOIUrl":"10.1016/S0338-9898(05)80200-8","url":null,"abstract":"<div><p>Les médecins exerçant en pays tropical sont fréquemment placés dans des situations où une formation minimale aux techniques de laboratoire s'avère très utile. Cette formation courte doit être adaptée à la fois aux besoins et aux techniques réalisables sur place. Elle doit contenir des techniques hématologiques de base, les examens directs en bactériologie et parasitologie en insistant particulièrement sur le diagnostic du paludisme. Le conditionnement et l'expédition des échantillons dans de bonnes conditions de sécurité vers un laboratoire de référence font aussi partie des objectifs pédagogiques. Selon les besoins, les stagiaires pourront aussi être formés à la détection des premiers cas dans le contexte d'épidémies de méningites à méningocoque ou de choléra. Cette formation courte doit enfin être prolongée par des documents pédagogiques et les CD Rom apparaissent comme les supports les mieux adaptés.</p></div><div><p>Physicians who have to work in tropical countries need frequently a minimal training for laboratory methods. This short training must be adapted to necessity and available methods on field as well. It must include basic haematological methods, direct examination in bacteriology and parasitology, with a special support on malaria diagnosis. Packaging and mailing of biological samples in adequate security conditions towards a reference laboratory are important aims of this training. In some cases, physicians may be trained for diagnosis of the first cases of meningococcal meningitis or cholera outbreaks. This short training must be proceeded with pedagogic documentation and CD Rom appear to be the most convenient materials.</p></div>","PeriodicalId":101129,"journal":{"name":"Revue Fran?aise des Laboratoires","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2005-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0338-9898(05)80200-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128925168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Problématique du diagnostic de la rage animale en milieu tropical","authors":"Jean-Lou Marié ,&nbsp;Hervé Bourhy ,&nbsp;Bernard Davoust","doi":"10.1016/S0338-9898(05)80197-0","DOIUrl":"10.1016/S0338-9898(05)80197-0","url":null,"abstract":"<div><p>Quasiment éradiquée d'Europe occidentale, la rage des animaux terrestres reste un problème de santé publique majeur dans la plupart des pays tropicaux. Le diagnostic sur animal, lorsque ce dernier peut être à l'origine d'une contamination humaine, est essentiel car il conditionne la nature de la prise en charge thérapeutique du patient. Les éléments épidémiologiques et cliniques permettent généralement d'établir une suspicion qui doit être confirmée par des tests spécifiques. Les analyses biologiques sont également précieuses pour la réalisation d'études épidémiologiques de terrain. Dans les laboratoires spécialisés, la recherche s'effectue par immunofluorescence directe, inoculation sur cultures cellulaires, sérologie et biologie moléculaire. L'amplification par RT-PCR, suivi du séquençage de certaines parties du génome, permet désormais de déterminer le génotype et l'origine géographique de la souche. Sur le terrain, les tests immunoenzymatiques qui pourraient être utilisés avec profit ne sont pas commercialisés et les différentes techniques de coloration manquent de spécificité ou de sensibilité. Lorsqu'il n'existe pas de laboratoire compétent disponible localement et lorsque les techniques de terrain ne sont pas accessibles, l'échantillon doit être acheminé à distance. Le respect des bonnes pratiques de prélèvement, d'emballage et de transport conditionne alors le résultat final.</p></div><div><p>Although nearly eradicated from the main part of Western Europe, land animal rabies remains a major public health concern in most of tropical countries. The diagnosis in an animal responsible for a potential human contamination is essential as it determines the treatment of the patient. Epidemiological and clinical information lead to a suspicion which must be confirmed using specific tests. Biological analyses are also essential to carry out field epidemiological studies. In specialized laboratories, tests include direct immunofluorescence, inoculation of cell culture, molecular biology, and serological examination. Amplification using RT-PCR and sequencing of specific gene fragments, make it possible to determine the genotype and the geographical origin of the strain. In the field, immunoenzymatic tests could be useful but are not commercially available and the different stain techniques are not sufficiently sensible or specific. When a competent laboratory cannot be found locally and when field techniques are not available, the sample must be sent to a distant laboratory. In this case, good practices in sampling, packaging and transport contribute in an essential way to the final result.</p></div>","PeriodicalId":101129,"journal":{"name":"Revue Fran?aise des Laboratoires","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2005-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0338-9898(05)80197-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125211539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Grippe aviaire : un danger sous-estimé ?","authors":"","doi":"10.1016/S0338-9898(05)80186-6","DOIUrl":"https://doi.org/10.1016/S0338-9898(05)80186-6","url":null,"abstract":"","PeriodicalId":101129,"journal":{"name":"Revue Fran?aise des Laboratoires","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2005-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0338-9898(05)80186-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137090948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Le vaccin antipneumococique réduirait aussi l'antibiorésistance","authors":"","doi":"10.1016/S0338-9898(05)80188-X","DOIUrl":"https://doi.org/10.1016/S0338-9898(05)80188-X","url":null,"abstract":"","PeriodicalId":101129,"journal":{"name":"Revue Fran?aise des Laboratoires","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2005-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0338-9898(05)80188-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137090951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modèle expérimental de transmission orale de l'ESB","authors":"","doi":"10.1016/S0338-9898(05)80192-1","DOIUrl":"https://doi.org/10.1016/S0338-9898(05)80192-1","url":null,"abstract":"","PeriodicalId":101129,"journal":{"name":"Revue Fran?aise des Laboratoires","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2005-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0338-9898(05)80192-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137091034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Les tuyaux en cuivre éloigneraient la légionelle des hôpitaux","authors":"J.-M.M.","doi":"10.1016/S0338-9898(05)80175-1","DOIUrl":"https://doi.org/10.1016/S0338-9898(05)80175-1","url":null,"abstract":"<div><p>Le cuivre serait le meilleur choix de matériau pour limiter la colonisation des réseaux de distribution d'eau sanitaire, principalement dans les hôpitaux, dont plusieurs se sont battu ou se battent encore contre <em>Legionella pneumophila</em>, qui apparaît à intervalles dans les canalisations des établissements de santé. Outre leur conductivité thermique hors du commun, qui est déterminante pour la désinfection par choc thermique, les canalisations en cuivre garantissent également une imperméabilité totale du réseau.</p></div>","PeriodicalId":101129,"journal":{"name":"Revue Fran?aise des Laboratoires","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2005-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0338-9898(05)80175-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136998464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Des marqueurs tumoraux pour le suivi thérapeutique","authors":"","doi":"10.1016/S0338-9898(05)80208-2","DOIUrl":"https://doi.org/10.1016/S0338-9898(05)80208-2","url":null,"abstract":"","PeriodicalId":101129,"journal":{"name":"Revue Fran?aise des Laboratoires","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2005-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0338-9898(05)80208-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89988873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alliance Maladies Rares, cinq ans après","authors":"J.-M.M.","doi":"10.1016/S0338-9898(05)80178-7","DOIUrl":"10.1016/S0338-9898(05)80178-7","url":null,"abstract":"","PeriodicalId":101129,"journal":{"name":"Revue Fran?aise des Laboratoires","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2005-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0338-9898(05)80178-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"102154653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diabète de type 2 : les gènes se suivent et ne se ressemblent pas","authors":"J.-M.M.","doi":"10.1016/S0338-9898(05)80174-X","DOIUrl":"https://doi.org/10.1016/S0338-9898(05)80174-X","url":null,"abstract":"<div><p>Le décryptage du terrain génétique du diabète de type 2 se poursuit. Deux nouvelles études indiquent que ce type de recherche reste fructueux.</p></div>","PeriodicalId":101129,"journal":{"name":"Revue Fran?aise des Laboratoires","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2005-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0338-9898(05)80174-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137090952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}