Revista Espa?ola de Enfermedades Metabólicas óseas最新文献

{"title":"Síndrome confusional agudo por adenoma paratiroideo: una enfermedad metabólica de tratamiento quirúrgico","authors":"V.J. Ovejero Gómez ,&nbsp;L. Nieto García ,&nbsp;Á. Pérez Martín ,&nbsp;I. Berrio Obregón ,&nbsp;J.R. López Lanza ,&nbsp;A. Ingelmo Setién","doi":"10.1016/S1132-8460(07)73512-2","DOIUrl":"10.1016/S1132-8460(07)73512-2","url":null,"abstract":"<div><p>El diagnóstico diferencial del síndrome confusional agudo abarca un gran número de procesos entre los que hay que considerar firmemente las enfermedades metabólicas. El diagnóstico del hiperparatiroidismo como causa del mismo debe apoyarse en parámetros biológicos, y su tratamiento tiene un enfoque inicial destinado a corregir el trastorno neuropsiquiátrico y otro definitivo basado en la cirugía para revertir la desmineralización ósea y la mortalidad ulterior relacionada con la hipercalcemia.</p><p>El abordaje quirúrgico debe efectuarse por cirujanos experimentados, cuyo objetivo principal conlleva la extirpación de la glándula enferma mediante técnicas lo menos agresivas posibles. Los estudios de imagen preoperatorios pueden contribuir a un abordaje selectivo que evite una exploración cervical bilateral. La determinación intraoperatoria de hormona paratiroidea intacta (PTHi), o el empleo de sonda isotópica, contribuyen a asegurar una solución quirúrgica efectiva.</p></div><div><p>The differential diagnosis of acute confusional state encompasses a large number of processes including metabolic diseases. The diagnosis of hyperparathyroidism as a cause of acute confusional state should rest on biological parameters; treatment should initially be focused on correcting the neuropsychological disorder and then definitive surgical treatment should be undertaken to reverse bone demineralization and ulterior mortality related to hypercalcemia.</p><p>The surgical approach should be carried out by experienced surgeons with the principal aim of extirpating the diseased gland using the least aggressive techniques possible. Preoperative imaging studies can help to ensure a selective approach that obviates bilateral cervical exploration. Intraoperative determination of intact parathyroid hormone (PTHi) levels or the use of a gamma probe help to ensure an effective surgical solution.</p></div>","PeriodicalId":101109,"journal":{"name":"Revista Espa?ola de Enfermedades Metabólicas óseas","volume":"16 6","pages":"Pages 130-132"},"PeriodicalIF":0.0,"publicationDate":"2007-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1132-8460(07)73512-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129951366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cáncer de paratiroides: revisión de literatura","authors":"A.A. Herrera ,&nbsp;P. Aranda ,&nbsp;J.A. Díaz","doi":"10.1016/S1132-8460(07)73511-0","DOIUrl":"10.1016/S1132-8460(07)73511-0","url":null,"abstract":"<div><h3>Justificación</h3><p>El cáncer de paratiroides es una entidad inusual; a pesar de lo anterior debe considerarse en el diagnóstico diferencial del hiperparatiroidismo primario.</p></div><div><h3>Objetivo</h3><p>Se realizó una revisión de la epidemiología, patogénesis, diagnóstico y terapéutica del cáncer de paratiroides.</p></div><div><h3>Materiales y métodos</h3><p>Se realizó una búsqueda en MedLine, según la metodología Cochrane, de artículos publicados desde enero de 1980 a enero de 2006 usando los términos «Parathyroid Carcinoma»; de esta búsqueda se seleccionaron los manuscritos considerados relevantes por parte de los autores.</p></div><div><h3>Conclusiones</h3><p>El cáncer de paratiroides debe tenerse en cuenta dentro del diagnóstico diferencial en casos de hiperparatiroidismo primario, pues un diagnóstico temprano permite mejores desenlaces en este tipo de pacientes.</p></div><div><h3>Justification</h3><p>Parathyroid cancer is uncommon; however, it should be considered in the differential diagnosis of primary hyperparathyroidism.</p></div><div><h3>Objective</h3><p>We review the epidemiology, pathogenesis, diagnosis, and treatment of parathyroid cancer.</p></div><div><h3>Materials and methods</h3><p>A MedLine search was carried out using the Cochrane methodology on articles published between January 1980 and January 2006 and the keywords «Parathyroid Carcinoma»; the articles found that were considered important were selected.</p></div><div><h3>Conclusions</h3><p>Parathyroid cancer should be taken into account in the differential diagnosis of cases of primary hyperparathyroidism, as an early diagnosis enables better outcomes in these patients.</p></div>","PeriodicalId":101109,"journal":{"name":"Revista Espa?ola de Enfermedades Metabólicas óseas","volume":"16 6","pages":"Pages 124-129"},"PeriodicalIF":0.0,"publicationDate":"2007-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1132-8460(07)73511-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127799937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"","doi":"10.1016/S1132-8460(07)74010-2","DOIUrl":"https://doi.org/10.1016/S1132-8460(07)74010-2","url":null,"abstract":"","PeriodicalId":101109,"journal":{"name":"Revista Espa?ola de Enfermedades Metabólicas óseas","volume":"16 5","pages":"Pages 95-110"},"PeriodicalIF":0.0,"publicationDate":"2007-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1132-8460(07)74010-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137344002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"","doi":"10.1016/S1132-8460(07)74012-6","DOIUrl":"https://doi.org/10.1016/S1132-8460(07)74012-6","url":null,"abstract":"","PeriodicalId":101109,"journal":{"name":"Revista Espa?ola de Enfermedades Metabólicas óseas","volume":"16 5","pages":"Page 112"},"PeriodicalIF":0.0,"publicationDate":"2007-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1132-8460(07)74012-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137344004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metabolismo, fuentes endógenas y exógenas de vitamina D","authors":"M.Á. Valero Zanuy ,&nbsp;F. Hawkins Carranza","doi":"10.1016/S1132-8460(07)73506-7","DOIUrl":"10.1016/S1132-8460(07)73506-7","url":null,"abstract":"<div><p>Hoy en día sabemos que la vitamina D se comporta como una hormona con múltiples funciones en el organismo. De todas sus acciones la mejor estudiada y la más importante se relaciona con la salud ósea. Los depósitos adecuados de la vitamina mantienen el metabolismo calcio-fósforo dentro de la normalidad. Las fuentes naturales principales son la síntesis cutánea de la hormona, inducida por la radiación solar y el aceite de pescado. En determinadas situaciones la síntesis cutánea no es del todo eficaz. Esto unido a que los alimentos naturales contienen escasa cantidad de vitamina D, hace que gran parte de la población esté en riesgo de presentar déficit/insuficiencia de este micronutriente. Por ello, diferentes autores recomiendan la ingesta de alimentos funcionales y de suplementos farmacológicos de la vitamina. Sin embargo, la fortificación de los alimentos naturales, tal y como se realiza en la actualidad, presenta varios problemas. De igual forma no existen unas recomendaciones universalmente aceptadas de cuánta cantidad de vitamina D se debe ingerir como suplemento farmacológico y qué población debe ingerirlo. Los datos disponibles señalan que la mayoría de la población se beneficiaría con la ingesta de 800 UI de vitamina D en combinación con calcio.</p></div><div><p>At present, we know that vitamin D behaves as a hormone with multiple functions in the body. The best studied and most important of all its actions is related with bone health. Adequate deposits of the vitamin maintain the calcium-phosphorus metabolism within normality limits. The main natural sources are solar radiation and fish oil induced cutaneous synthesis of the hormone. In certain situation, cutaneous synthesis is not completely effective. This, together with the fact that natural foods contain scarce amounts of vitamin D, causes a large part of the population to be at risk of having a deficit/insufficiency of this micronutrient. Thus, different authors recommend the intake of functional foods and drug supplements of the vitamin. However, fortification of natural foods, as is presently done, has several problems. Furthermore, there are no universally accepted recommendations for the amount of vitamin D that should be taken as a drug supplement and which population should take it. The data available indicate that most of the population would benefit from taking 800 IU of vitamin D combined with calcium.</p></div>","PeriodicalId":101109,"journal":{"name":"Revista Espa?ola de Enfermedades Metabólicas óseas","volume":"16 4","pages":"Pages 63-70"},"PeriodicalIF":0.0,"publicationDate":"2007-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1132-8460(07)73506-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"112762431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"","doi":"10.1016/S1132-8460(07)74009-6","DOIUrl":"https://doi.org/10.1016/S1132-8460(07)74009-6","url":null,"abstract":"","PeriodicalId":101109,"journal":{"name":"Revista Espa?ola de Enfermedades Metabólicas óseas","volume":"16 5","pages":"Pages 85-94"},"PeriodicalIF":0.0,"publicationDate":"2007-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1132-8460(07)74009-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137344001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"","doi":"10.1016/S1132-8460(07)74011-4","DOIUrl":"https://doi.org/10.1016/S1132-8460(07)74011-4","url":null,"abstract":"","PeriodicalId":101109,"journal":{"name":"Revista Espa?ola de Enfermedades Metabólicas óseas","volume":"16 5","pages":"Page 111"},"PeriodicalIF":0.0,"publicationDate":"2007-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1132-8460(07)74011-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137344003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"","doi":"10.1016/S1132-8460(07)74014-X","DOIUrl":"https://doi.org/10.1016/S1132-8460(07)74014-X","url":null,"abstract":"","PeriodicalId":101109,"journal":{"name":"Revista Espa?ola de Enfermedades Metabólicas óseas","volume":"16 5","pages":"Pages 115-117"},"PeriodicalIF":0.0,"publicationDate":"2007-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1132-8460(07)74014-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137344006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Máxima evidencia y de mejor calidad en metaanálisis de bifosfonatos para el tratamiento de la osteoporosis en mujeres posmenopáusicas","authors":"A. De Castro","doi":"10.1016/S1132-8460(07)73507-9","DOIUrl":"10.1016/S1132-8460(07)73507-9","url":null,"abstract":"<div><h3>Introducción</h3><p>Se han realizado numerosos metaanálisis de bifosfonatos para el tratamiento de la osteoporosis, pero no se ha realizado una revisión sistemática de todos ellos.</p></div><div><h3>Objetivo</h3><p>Recoger y analizar los metaanálisis publicados con el objeto de conocer cuántos hay, con qué bifosfonatos, su calidad metodológica y Conclusiones.</p></div><div><h3>Metodología</h3><p>Se realizaron búsquedas en MEDLINE, EMBASE y Cochrane para los últimos 10 años restringiéndose por idioma. Se incluyeron 13 estudios de metaanálisis en los que se evaluaba la eficacia en la reducción de fractura vertebral (FV), no vertebral (FNV) o de cadera en alendronato y risedronato y FV y FNV para etidronato. Se obtuvo un metaanálisis de bifosfonatos combinados. Se evaluaron los datos resumidos de cada estudio y su calidad metodológica.</p></div><div><h3>Resultados</h3><p>Risedronato y alendronato han demostrado ser eficaces en la reducción de FV y FNV. Ninguno ha demostrado superioridad de eficacia, sólo un metaanálisis de alendronato obtuvo dicho resultado, pero utilizando datos no adecuados. En la reducción de fracturas de cadera los metaanálisis muestran a ambos eficaces, aunque risedronato es el único bifosfonato que lo ha demostrado a través de un ensayo clínico diseñado para ello.</p></div><div><h3>Conclusiones</h3><p>Existe un no despreciable número de metaanálisis de bifosfonatos de calidad metodológica aceptable. Aunque no todos se han realizado con máxima calidad, usando datos individuales de pacientes, la mayor parte de ellos son metodológicamente correctos habiéndose obtenido resultados similares entre ellos, siempre que se han realizado análisis por intención de tratar y se han incluido todos los estudios relevantes.</p></div><div><h3>Introduction</h3><p>Many meta-analyses of bisphosphonates for the treatment of osteoporosis have been made. However. no systematic review of them has been performed.</p></div><div><h3>Objective</h3><p>Collect and analyze the meta-analyses published in order to know how many there are, with what bisphosphonates, their methodological quality and conclusions.</p></div><div><h3>Methodology</h3><p>Searches were made in MEDLINE, EMBASE and Cochrane for the last 10 years, restricting them by language. Thirteen meta-analysis studies were included, in which efficacy in the reduction of vertebral fracture (VF), non-vertebral fracture (NVF) or hip fracture for alendronate and risedronate and VF and NVF for etidronate was evaluated. A meta-analysis of combined bisphosphonates was obtained. The data summarized from each study and their methodological quality were evaluated.</p></div><div><h3>Results</h3><p>Risedronate and alendronate have been demonstrated to be effective in the reduction of VF and NVF. None have demonstrated superiority of efficacy and only one meta-analysis of alendronate obtained these results, but using inadequate data. In the reduction of hip fractures, the meta-analyses showed that both ","PeriodicalId":101109,"journal":{"name":"Revista Espa?ola de Enfermedades Metabólicas óseas","volume":"16 4","pages":"Pages 71-81"},"PeriodicalIF":0.0,"publicationDate":"2007-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1132-8460(07)73507-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114937889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mujer con dolor y tumoración en el arco plantar del pie izquierdo","authors":"M.Á. Contreras Blasco","doi":"10.1016/S1132-8460(07)73509-2","DOIUrl":"10.1016/S1132-8460(07)73509-2","url":null,"abstract":"","PeriodicalId":101109,"journal":{"name":"Revista Espa?ola de Enfermedades Metabólicas óseas","volume":"16 4","pages":"Page 84"},"PeriodicalIF":0.0,"publicationDate":"2007-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1132-8460(07)73509-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114027941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}