Revista Espa?ola de Enfermedades Metabólicas óseas最新文献

{"title":"Desarrollo y validaci n de un cuestionario predictivo de osteoporosis (OPARG score)","authors":"D.A. Pate,&nbsp;O.D. Messina","doi":"10.1016/S1132-8460(06)75259-X","DOIUrl":"10.1016/S1132-8460(06)75259-X","url":null,"abstract":"<div><h3>Introducción</h3><p>Se encuentran descritos múltiples factores de riesgo (FR) asociados a la osteoporosis. Evaluamos la capacidad predictiva, individual y colectiva de los mismos. El trabajo consta de dos fases sucesivas; inicialmente se desarrolló un modelo predictivo y luego se validó prospectivamente.</p></div><div><h3>Materiales y métodos</h3><p>Se construyó un cuestionario de FR y se interrogó a las mujeres que participaron antes de realizar absorciometría dual de rayos X (DEXA). Se diseñó un modelo predictivo y se aplicó en una nueva población.</p></div><div><h3>Resultados</h3><p>Fase inicial: 785 mujeres (osteoporosis: 26,11%). La edad, postmenopausia, datos antropométricos y antecedentes de fracturas demostraron ser los FR más relevantes. El modelo es aplicable a mujeres postmenopáusicas. Fase de validación: 502 pacientes postmenopáusicas (osteoporosis: 27,49%). Se puso de manifiesto una correlación significativa entre lo observado en la población estudiada y lo predicho por el modelo.</p></div><div><h3>Conclusión</h3><p>Una puntuación mayor o igual a 3 es indicación de realizar un procedimiento diagnóstico. Este método puede utilizarse para optimizar la selección de pacientes de mayor riesgo.</p></div><div><h3>Introduction</h3><p>Several risk factors (RF) have been associated to the development of osteoporosis. We have evaluated the predictive capacity of many of them in two phases. Initially we developed a predictive score and then we validated the model prospectively.</p></div><div><h3>Material and methods</h3><p>A questionnaire on RF was designed. The women were questioned prior to performing a bone mineral density measurement by DXA. A predictive score was designed. This was applied to a new population.</p></div><div><h3>Results</h3><p>During the first phase 785 women were included. 26.11% of them were diagnosed as having osteoporosis according to the WHO definition. Age, postmenopausal state, personal history of fracture and weight were shown to be the most relevant RF. The score is applicable to postmenopausal women.</p><p>Validation phase 502 postmenopausal women (osteoporosis: 27.49%) were included. A significant correlation was observed between that observed in the population studied and that predicted by the score.</p></div><div><h3>Conclusion</h3><p>A score ≥ 3 warranted performing a diagnostic procedure. This method may be used to optimize identifying patients at high risk.</p></div>","PeriodicalId":101109,"journal":{"name":"Revista Espa?ola de Enfermedades Metabólicas óseas","volume":"15 3","pages":"Pages 39-43"},"PeriodicalIF":0.0,"publicationDate":"2006-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1132-8460(06)75259-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122915460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factores que influyen en el cumplimiento terap utico en la osteoporosis","authors":"N. Guañabens","doi":"10.1016/S1132-8460(06)75260-6","DOIUrl":"10.1016/S1132-8460(06)75260-6","url":null,"abstract":"<div><p>El cumplimiento terapéutico es un reto en la práctica clínica. Así, en los últimos años se ha evidenciado que los pacientes con enfermedades crónicas como la osteoporosis tienen un bajo cumplimiento de la medicación recomendada. Recientemente se han identificado los factores que influyen en el cumplimiento, destacando aspectos sociales y económicos, factores relacionados con la enfermedad de base y con el propio tratamiento, y por último con las características del paciente. En este artículo se revisan estos aspectos, con el interés de ofrecer una visión global de los factores implicados en el bajo cumplimiento terapéutico en la osteoporosis.</p></div><div><p>Compliance with drug therapies is a key point in clinical practice. In the last years, awareness about the poor compliance with medications in chronic disorders such as osteoporosis has emerged. In addition, most factors that influence compliance with prescribed medications have been identified. They include social and economic aspects, illness and treatment related factors as well as patient characteristics. This article is focused on data concerning the factors responsible for poor compliance with drug therapies in osteoporosis.</p></div>","PeriodicalId":101109,"journal":{"name":"Revista Espa?ola de Enfermedades Metabólicas óseas","volume":"15 3","pages":"Pages 44-46"},"PeriodicalIF":0.0,"publicationDate":"2006-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1132-8460(06)75260-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123847633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efecto de la terapia biol gica sobre el metabolismo seo en las enfermedades inflamatorias articulares","authors":"M.V. Hernández","doi":"10.1016/S1132-8460(06)75263-1","DOIUrl":"https://doi.org/10.1016/S1132-8460(06)75263-1","url":null,"abstract":"","PeriodicalId":101109,"journal":{"name":"Revista Espa?ola de Enfermedades Metabólicas óseas","volume":"15 3","pages":"Pages 52-54"},"PeriodicalIF":0.0,"publicationDate":"2006-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1132-8460(06)75263-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92139219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Osteonecrosis de la cabeza femoral","authors":"E. González Reimers ,&nbsp;M. Arnay de la Rosa ,&nbsp;J. Velasco-Vázquez","doi":"10.1016/S1132-8460(06)75261-8","DOIUrl":"10.1016/S1132-8460(06)75261-8","url":null,"abstract":"","PeriodicalId":101109,"journal":{"name":"Revista Espa?ola de Enfermedades Metabólicas óseas","volume":"15 3","pages":"Pages 47-48"},"PeriodicalIF":0.0,"publicationDate":"2006-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1132-8460(06)75261-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121668196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Special report on the official positions of the international society for clinical densitometry","authors":"M.J. Peña Millán","doi":"10.1016/S1132-8460(06)75262-X","DOIUrl":"10.1016/S1132-8460(06)75262-X","url":null,"abstract":"","PeriodicalId":101109,"journal":{"name":"Revista Espa?ola de Enfermedades Metabólicas óseas","volume":"15 3","pages":"Pages 49-51"},"PeriodicalIF":0.0,"publicationDate":"2006-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1132-8460(06)75262-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121746607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inhibidores de la aromatasa y osteoporosis","authors":"X. Nogués I Solán","doi":"10.1016/S1132-8460(06)75264-3","DOIUrl":"https://doi.org/10.1016/S1132-8460(06)75264-3","url":null,"abstract":"","PeriodicalId":101109,"journal":{"name":"Revista Espa?ola de Enfermedades Metabólicas óseas","volume":"15 3","pages":"Pages 55-56"},"PeriodicalIF":0.0,"publicationDate":"2006-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1132-8460(06)75264-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92091028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Osteoporosis en medicina interna. Ha sido til el estudio cosmis?","authors":"J. Calvo Catalá ,&nbsp;J.J. García-Borrás ,&nbsp;C. Campos Fernández ,&nbsp;A. Baixauli Rubio ,&nbsp;M. Muñoz Guillém ,&nbsp;M.I. González-Cruz ,&nbsp;J.L. Valero Sanz","doi":"10.1016/S1132-8460(06)75254-0","DOIUrl":"10.1016/S1132-8460(06)75254-0","url":null,"abstract":"<div><h3>Introducción</h3><p>La osteoporosis, a pesar de ser la enfermedad metabólica ósea más frecuente, está infradiagnosticada y, por tanto, infratratada.</p></div><div><h3>Pacientes y métodos</h3><p>Para conocer la situación en que se encontraba esta patología en los servicios de Medicina Interna, en el año 2003, se desarrolló el proyecto COSMIS (Conocimiento de la Osteoporosis en los Servicios de Medicina Interna SEIOMM), estudio que confirmó los datos esperados, con un diagnóstico de osteoporosis en pacientes mayores de 60 años de un 3,4%. Sólo un 3,1% recibía tratamiento correcto.</p></div><div><h3>Resultados</h3><p>Dos años después, hemos revalorado los mismos parámetros en dos hospitales que intervinieron en el primer estudio, obteniendo unos resultados semejantes. A pesar de los numerosos factores de riesgo detectados en los pacientes y de las fracturas vertebrales reseñadas, la osteoporosis sigue estando poco diagnosticada y poco tratada.</p></div><div><h3>Conclusiones</h3><p>Nuevos estudios, grupos de trabajo, etc., pueden contribuir a mejorar esta situación, siendo importante la colaboración de las autoridades sanitarias mediante planes que apoyen esta enfermedad tan prevalente y con tan importantes consecuencia socioeconómicas.</p></div><div><h3>Introduction</h3><p>In spite of being the most frequent metabolic disease, osteoporosis is under-diagnosed and under-treated.</p></div><div><h3>Patients and methods</h3><p>The COSMIS project (Knowledge of Osteoporosis in Internal Medicine Services SEIOMM) was developed in 2003 in order to know osteoporosis patterns in Internal Medicine Services. This study confirmed the expected data, with a 3.4% diagnosis of osteoporosis in those over 60 years of age. Only 3.1% were receiving correct treatment.</p></div><div><h3>Results</h3><p>Two years later, we reevaluated the same parameters in two Hospitals that participated in the first study, obtaining similar results. In spite of the many risk factors detected in the patients and of the vertebral fractures reviewed, osteoporosis continues to be under-diagnosed and under-treated. The small relationship with the many risk factors detected and even with the vertebral fractures is striking.</p></div><div><h3>Conclusions</h3><p>Our studies, work groups, etc. may contribute to improve this situation, collaboration of the regulatory authorities by plans that support such a prevalent disease with such important socioeconomic consequences being important.</p></div>","PeriodicalId":101109,"journal":{"name":"Revista Espa?ola de Enfermedades Metabólicas óseas","volume":"15 2","pages":"Pages 21-23"},"PeriodicalIF":0.0,"publicationDate":"2006-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1132-8460(06)75254-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131818475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Es posible la comparaci n de f rmacos head to head en osteoporosis?","authors":"X. Nogués y Solán","doi":"10.1016/S1132-8460(06)75258-8","DOIUrl":"https://doi.org/10.1016/S1132-8460(06)75258-8","url":null,"abstract":"","PeriodicalId":101109,"journal":{"name":"Revista Espa?ola de Enfermedades Metabólicas óseas","volume":"15 2","pages":"Pages 37-38"},"PeriodicalIF":0.0,"publicationDate":"2006-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1132-8460(06)75258-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91633011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Los fitoestr genos como agentes moduladores del metabolismo seo","authors":"A.R. de Gortázar","doi":"10.1016/S1132-8460(06)75257-6","DOIUrl":"10.1016/S1132-8460(06)75257-6","url":null,"abstract":"","PeriodicalId":101109,"journal":{"name":"Revista Espa?ola de Enfermedades Metabólicas óseas","volume":"15 2","pages":"Pages 34-36"},"PeriodicalIF":0.0,"publicationDate":"2006-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1132-8460(06)75257-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130678151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tratamiento de la osteoporosis en la mujer premenop usica","authors":"P. Peris","doi":"10.1016/S1132-8460(06)75256-4","DOIUrl":"https://doi.org/10.1016/S1132-8460(06)75256-4","url":null,"abstract":"","PeriodicalId":101109,"journal":{"name":"Revista Espa?ola de Enfermedades Metabólicas óseas","volume":"15 2","pages":"Pages 30-33"},"PeriodicalIF":0.0,"publicationDate":"2006-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1132-8460(06)75256-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91633013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}