Revista del Laboratorio Clínico最新文献_第5页

Oncología personalizada: principales biomarcadores en el pronóstico y tratamiento de tumores sólidos 个性化肿瘤学:实体肿瘤预后和治疗中的主要生物标志物

Revista del Laboratorio Clínico Pub Date : 2019-07-01 DOI: 10.1016/J.LABCLI.2018.11.001

Marta Molina Romero, E. J. L. Mendieta, Gema María Varo Sánchez, M. C. Alonso-Cerezo, M. O. Clemente

引用次数: 1

About the correct definition of acanthocytes for their use as markers of glomerular haematuria 关于棘细胞作为肾小球血尿标志物的正确定义

Revista del Laboratorio Clínico Pub Date : 2019-07-01 DOI: 10.1016/j.labcli.2019.02.004

Sofía Zaera, Noa Villar-Mallo, Marta González Vilanova, María Carmen Díaz Lozano, Juan J. Garrido-Sánchez, Lola Máiz Suárez

引用次数: 1

Las proteasas de serina bacterianas y su implicación en la fisiopatología de la infección 细菌丝氨酸蛋白酶及其在感染病理生理学中的作用

Revista del Laboratorio Clínico Pub Date : 2019-07-01 DOI: 10.1016/j.labcli.2019.02.003

Gerardo García-González, Gloria María González, José P. Palma-Nicolás

引用次数: 0

Interferencia por ácido 2,4-diamino-N10-metilpteroico en la determinación de metotrexato tras la administración de glucarpidasa

Revista del Laboratorio Clínico Pub Date : 2019-07-01 DOI: 10.1016/J.LABCLI.2018.08.003

Nazaret del Amo del Arco, Raquel Ramos Corral, Javier López Flores, Yessika M. Amezquita Orjuela, Alicia Roldán Pérez, F. Valenciano

引用次数: 1

Recomendaciones para la estandarización de la medida de lípidos y lipoproteínas. Recomendación (2018) 脂质和脂蛋白测量标准化的建议。建议(2018年)

Revista del Laboratorio Clínico Pub Date : 2019-07-01 DOI: 10.1016/j.labcli.2018.08.002

Juan Carlos Vella Ramírez, Enrique Rodríguez García, Carlos Romero Román, Beatriz Candás Estébanez, María José Castro Castro, Teresa Arrobas Velilla, Pilar Calmarza Calmarza, Margarita Esteban Salán, Miguel Pocoví Mieras, José Puzo Foncillas

{"title":"Recomendaciones para la estandarización de la medida de lípidos y lipoproteínas. Recomendación (2018)","authors":"Juan Carlos Vella Ramírez, Enrique Rodríguez García, Carlos Romero Román, Beatriz Candás Estébanez, María José Castro Castro, Teresa Arrobas Velilla, Pilar Calmarza Calmarza, Margarita Esteban Salán, Miguel Pocoví Mieras, José Puzo Foncillas","doi":"10.1016/j.labcli.2018.08.002","DOIUrl":"10.1016/j.labcli.2018.08.002","url":null,"abstract":"<div><p>Some recommendations are presented for standardising the measurement of lipids and lipoproteins, as they are critical for clinical decisions making. Recommended methods validated against a reference or definitive method should be employed, as well as the use of control materials that comply with European Directives on <em>in vitro</em> diagnostics. Additionally, the chosen methods must comply with the objectives set forth by the National Cholesterol Education Program (NCEP) and by the Spanish Society of Laboratory Medicine (SEQC<sup>ML</sup>). Determination of HDL cholesterol using automatic homogenous methods is considered acceptable for normal clinical practice, and the Friedewald Formula is considered to be usable to estimate LDL cholesterol concentration when triglyceride concentrations are below 200mg/dL (2.3mmol/L). If this should not be the case, the use of non-HDL cholesterol is recommended. Routine quantification of apolipoproteins A1 and B, and lipoprotein (a) can be measured using immunonephelometric or immunoturbidimetric methods, with calibrators that are traceable to reference materials.</p></div>","PeriodicalId":101105,"journal":{"name":"Revista del Laboratorio Clínico","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.labcli.2018.08.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81945354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Síndrome de Sweet mielodisplásico corticodependiente. A propósito de un caso 糖皮质激素依赖性骨髓增生不良综合征。关于一个案例

Revista del Laboratorio Clínico Pub Date : 2019-04-01 DOI: 10.1016/J.LABCLI.2018.06.002

C. García, Á. D. L. Torre, M. D. Prados, R. H. Sánchez, A. E. Armada, R. C. León

引用次数: 0

Nuevos tiempos clínicos para Streptococcus vestibularis 前庭链球菌的新临床时间

Revista del Laboratorio Clínico Pub Date : 2019-04-01 DOI: 10.1016/j.labcli.2018.03.004

Carlos Jiménez-Mascuñán, José Gutiérrez-Fernández

{"title":"Nuevos tiempos clínicos para Streptococcus vestibularis","authors":"Carlos Jiménez-Mascuñán, José Gutiérrez-Fernández","doi":"10.1016/j.labcli.2018.03.004","DOIUrl":"https://doi.org/10.1016/j.labcli.2018.03.004","url":null,"abstract":"<div><p><em>Streptococcus vestibularis</em>, which has been described at the beginning of last century, has been isolated from different sources (oral cavity, stomach or jejunum, for instance). Regarding its denomination, this microorganism was named after its first isolation source (mucosa from <em>oris vestibulum</em>). In spite of great difficulties in the taxonomy of <em>viridans</em> group streptococci, genetic tests have recently made it possible to distinguish <em>S. vestibularis</em> from other species of the same group, even from those phylogenetically close to it (<em>Streptococcus salivarius</em> and <em>Streptococcus thermophilus</em>). Studies on this bacteria have revealed it possess a considerable number of virulence factors, which may provide it with notable virulence regardless of its opportunistic pathogen behaviour. Identification of <em>viridans</em> group streptococci is also difficult, as phenotypic methods have shown to be troublesome. Nevertheless, sequence-based methods (rRNA 16S) or MALDI-TOF offer relatively reliable identifications, despite the lack of information about these species. Antibiotic susceptibility of <em>S</em>. <em>vestibularis</em> has been poorly studied, as this species is rarely isolated in day-to-day clinical practice in relation to infections. As a result of this, the antibiotic susceptibility profile of this bacteria is based on general information about antibiotic susceptibility of <em>viridans</em> group streptococci.</p></div>","PeriodicalId":101105,"journal":{"name":"Revista del Laboratorio Clínico","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.labcli.2018.03.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91631327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Síndrome de Sweet mielodisplásico corticodependiente. A propósito de un caso 糖皮质激素依赖性骨髓增生不良综合征。关于一个案例

Revista del Laboratorio Clínico Pub Date : 2019-04-01 DOI: 10.1016/j.labcli.2018.06.002

Carmen Ortiz García , Ángela García de la Torre , María Victoria de la Torre Prados , Ramón Hidalgo Sánchez , Alfredo Enguix Armada , Rafael Camino León

{"title":"Síndrome de Sweet mielodisplásico corticodependiente. A propósito de un caso","authors":"Carmen Ortiz García , Ángela García de la Torre , María Victoria de la Torre Prados , Ramón Hidalgo Sánchez , Alfredo Enguix Armada , Rafael Camino León","doi":"10.1016/j.labcli.2018.06.002","DOIUrl":"https://doi.org/10.1016/j.labcli.2018.06.002","url":null,"abstract":"<div><h3>Background and objective</h3><p>Sweet's syndrome or acute febrile neutrophilic dermatosis is a rare inflammatory disease of unknown pathophysiology, although clinical and biochemical evidence suggests that cytokines play an important role in its aetiopathogenesis. It is classified into five groups: idiopathic, para-inflammatory, secondary to drugs, associated with pregnancy, and para-neoplastic in 20% of cases, with 85% of these linked to haematological disorders, and 15% to solid tumours.</p></div><div><h3>Patient</h3><p>A report is presented on a patient with Sweet's Syndrome with atypical dermatological involvement, associated with myelodysplastic syndrome, and iatrogenic Cushing's syndrome secondary to high-doses of corticosteroids, with an unfavorable outcome.</p></div><div><h3>Results</h3><p>Acute phase reactants (APR) were increased during the outbreaks, with the early elevation of interleukin 6 (IL6) being highlighted, followed by serum amyloid A (SAA) and C-reactive protein (CRP), with statistically significant differences (<em>P</em><.05) between CRP and SAA.</p></div><div><h3>Conclusions</h3><p>A Sweet's syndrome in a male with multiple relapses and a non-classical dermatological location, associated haematological abnormalities, and an increase in APR with early elevation of IL6, should lead to a clinical diagnosis of paraneoplastic and haematological origin.</p></div>","PeriodicalId":101105,"journal":{"name":"Revista del Laboratorio Clínico","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91631328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Citopatología y bioquímica del líquido pleural reumatoideo. A propósito de un caso 类风湿胸膜液的细胞病理学和生物化学。关于一个案例

Revista del Laboratorio Clínico Pub Date : 2019-04-01 DOI: 10.1016/j.labcli.2018.07.001

Francisco M. Páez Codeso , María Pilar Pérez Soriano , Estefanía Casado Miranda , Antonio Dorado Galindo , M. Dolores Bautista Ojeda

引用次数: 1

Nuevos tiempos clínicos para Streptococcus vestibularis 前庭链球菌的新临床时间

Revista del Laboratorio Clínico Pub Date : 2019-04-01 DOI: 10.1016/J.LABCLI.2018.03.004

Carlos Jiménez-Mascuñán, José Gutiérrez-Fernández

引用次数: 1