{"title":"Idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN). Case report and literature review","authors":"Daniela Giraldo Ochoa , Silvia Caballero Mojica , John Camilo Hernández Foronda , Miguel Cuevas Peláez , Martha Lucia Muñoz Cardona","doi":"10.1016/j.rcreue.2022.08.002","DOIUrl":"10.1016/j.rcreue.2022.08.002","url":null,"abstract":"<div><p>Idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) is an infrequent disease, of as yet unknown aetiology, which affects the retina with no systemic injury, causing progressive retinal ischaemia and visual loss. We describe the case of a Colombian patient with a diagnosis of IRVAN guided by clinical examination and diagnostic images, after previously ruling out other ocular infections, autoimmune, or systemic diseases. Our patient was treated with peripheral laser, intravitreous anti-VEGF, and systemic immunosuppression with excellent response. In conclusion, early diagnosis and proper treatment according to disease stage could improve visual prognosis.</p></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"31 1","pages":"Pages 117-121"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141136114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sneider Alexander Torres-Soto , Laura Andrea Silva-Quintero , Wilmer Gerardo Rojas-Zuleta
{"title":"Psoriatic march: A view from pathophysiology to cardiovascular risk","authors":"Sneider Alexander Torres-Soto , Laura Andrea Silva-Quintero , Wilmer Gerardo Rojas-Zuleta","doi":"10.1016/j.rcreue.2022.03.007","DOIUrl":"10.1016/j.rcreue.2022.03.007","url":null,"abstract":"<div><p>Psoriasis is a disease that is not limited to skin involvement, the importance of systemic compromise is recognized more than ever, especially because of the associated comorbidities, which are explained by the marked chronic systemic inflammatory response mediated by pro-inflammatory cytokines (mainly TNF-α, IL23, IL 17), which play an important role in the induction of insulin resistance, endothelial dysfunction, accelerated atherosclerosis and the increased risk of cardio-cerebrovascular events. The relationship with these outcomes has been demonstrated and hence the concept of psoriatic march, a term that is gaining increasing importance aimed at maintaining and reinforcing the approach to a skin disease with systemic compromise, associated morbidity and mortality that can be preventable and manageable. The pathophysiological mechanisms that explain these phenomena are variable, however, new concepts have been identified, which have made it possible to improve the current approach to the disease and thus establish mechanisms to reduce cardiovascular risk in patients with psoriasis.</p></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"31 1","pages":"Pages 18-28"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140777471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
María Paulina Villa Saldarriaga , Yessica Andrea Barrera Marín , Jennifer Posada Caro , Juliana Gómez Mesa , Felipe Carrasco Vélez , Libia María Rodríguez Padilla , Felipe Campo Campo , Carlos Jaime Velásquez Franco , Miguel Antonio Mesa Navas , María Fernanda Álvarez Barreneche
{"title":"Characterization of patients with idiopathic interstitial pulmonary disease and capillary and laboratory findings in two health institutions in Medellín, Colombia: A descriptive study","authors":"María Paulina Villa Saldarriaga , Yessica Andrea Barrera Marín , Jennifer Posada Caro , Juliana Gómez Mesa , Felipe Carrasco Vélez , Libia María Rodríguez Padilla , Felipe Campo Campo , Carlos Jaime Velásquez Franco , Miguel Antonio Mesa Navas , María Fernanda Álvarez Barreneche","doi":"10.1016/j.rcreue.2024.04.002","DOIUrl":"10.1016/j.rcreue.2024.04.002","url":null,"abstract":"<div><h3>Introduction</h3><p>Interstitial lung disease (ILD) usually has a poor therapeutic response and prognosis. One of the methods that could help in the diagnosis and optimize the management of these patients is capillaroscopy. The study aimed to determine the clinical and capillaroscopic characteristics of patients with ILD and the frequency of findings suggestive of autoimmune disease.</p></div><div><h3>Materials and methods</h3><p>A descriptive observational study that evaluated patients with ILD treated between 2010 and 2019 without a previous diagnosis of autoimmune disease. An interview, capillaroscopy, and laboratory tests were performed.</p></div><div><h3>Results</h3><p>28 patients were evaluated, 16 (57.1%) were women and 17 (60.7%) had hypertension. Three patients (10.7%) reported morning stiffness for more than 60 minutes and there was one unexplained digital edema. There were no telangiectasias, Raynaud’s phenomenon, mechanic’s hands, sclerodactyly or Gottron’s sign, or ANAS titres greater than 1:80. The rest of the laboratory tests were negative in 100% of the patients. In the capillaroscopies, 13 (46.4%) patients had a normal capillaroscopic pattern, and 15 (53.6%) had capillaroscopic abnormalities of undetermined significance. There were none with a pattern of systemic sclerosis or similar.</p></div><div><h3>Conclusions</h3><p>No laboratory or capillaroscopy findings were found that suggested interstitial disease with autoimmune features, possibly due to the low prevalence of the disease, its high mortality, and underdiagnosis. These findings reinforce the concept of capillaroscopic normality in patients with non-autoimmune ILD and call for an active search for ILD with autoimmune features for prognostic purposes.</p></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"31 1","pages":"Pages 44-50"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141052658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ben Ayed Hiba , Fazaa Alia , Ouenniche Kmar , Miladi Saoussen , Sellami Mariem , Souabni Leila , Kassab Selma , Chekili Selma , Ben Abdelghani Kaouther , Laatar Ahmed
{"title":"Retrobulbar optic neuritis in a patient with enteropathic spondyloarthritis treated with tumour necrosis factor inhibitors","authors":"Ben Ayed Hiba , Fazaa Alia , Ouenniche Kmar , Miladi Saoussen , Sellami Mariem , Souabni Leila , Kassab Selma , Chekili Selma , Ben Abdelghani Kaouther , Laatar Ahmed","doi":"10.1016/j.rcreue.2022.02.002","DOIUrl":"https://doi.org/10.1016/j.rcreue.2022.02.002","url":null,"abstract":"<div><p>Optic neuritis is a rare ocular manifestation of inflammatory bowel diseases and spondyloarthritis. The use of tumour necrosis alpha inhibitors to treat these conditions remains possible. We report a case of a 62-year-old-woman with a 17 year-history of axial and peripheral spondyloarthritis associated with Crohn's disease, treated with tumour necrosis alpha inhibitors, who developed an asymmetric retrobulbar optic neuritis that promptly responded to a high dose of steroids.</p></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"31 1","pages":"Pages 84-87"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141244588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Severe interstitial lung disease in a patient with anti-PL7 antisynthetase syndrome","authors":"Sebastián Molina-Ríos , Gerardo Quintana-López","doi":"10.1016/j.rcreue.2024.04.001","DOIUrl":"10.1016/j.rcreue.2024.04.001","url":null,"abstract":"<div><p>Antisynthetase syndrome is a rare disease, with varying degrees of lung, muscle, joint, and skin involvement. Due to the introduction of new diagnostic tests, it is possible to detect the disease earlier and to determine the best treatment strategy. However, in our country the availability of these tests is limited. We present the case of a patient with antisynthetase syndrome associated with anti-PL7 antibodies in whom, thanks to the early identification of these antibodies, timely initiation of treatment for the disease was achieved.</p></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"31 1","pages":"Pages 103-108"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141056837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Splenic infarction as presentation of antiphospholipid syndrome and systemic lupus erythematosus: A case report","authors":"Johan Azañero-Haro , Liliana Chambi , Alonso Soto","doi":"10.1016/j.rcreue.2022.07.004","DOIUrl":"10.1016/j.rcreue.2022.07.004","url":null,"abstract":"<div><p>Splenic infarction is a rare condition usually associated with systemic conditions. Antiphospholipid syndrome (APS) is an autoimmune condition that can present as abdominal pain due to splenic infarction. We describe a patient with systemic lupus erythematosus, admitted due to acute abdominal pain. Abdominal CT scan showed splenic infarction, and tests for antiphospholipid and anti-β2-glycoprotein I antibodies were positive. The pathophysiology and clinical presentation of splenic infarction associated with APS is discussed, emphasizing the importance of including this entity in the differential diagnosis of abdominal pain of uncertain cause in patients with systemic conditions.</p></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"31 1","pages":"Pages 127-132"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141141984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gustavo Adolfo Castilla Agudelo , Libia María Rodríguez Padilla , Sergio Jaramillo Velásquez , Lady Johanna Hernández Zapata , Miguel Antonio Mesa Navas , María Fernanda Álvarez Barreneche , Carlos Jaime Velásquez Franco
{"title":"Determination of the 99th percentile of anticardiolipin and anti-β2 glycoprotein I antibodies in an institution in the city of Medellin, Colombia","authors":"Gustavo Adolfo Castilla Agudelo , Libia María Rodríguez Padilla , Sergio Jaramillo Velásquez , Lady Johanna Hernández Zapata , Miguel Antonio Mesa Navas , María Fernanda Álvarez Barreneche , Carlos Jaime Velásquez Franco","doi":"10.1016/j.rcreue.2022.01.003","DOIUrl":"10.1016/j.rcreue.2022.01.003","url":null,"abstract":"<div><h3>Introduction</h3><p>Antiphospholipid syndrome diagnosis requires abnormal results of lupus anticoagulant and high titles of anticardiolipin (aCL) and β2glycoprotein I (anti-β2GPI) antibodies. The latter immunological tests lack a standard threshold in clinical practice.</p></div><div><h3>Objective</h3><p>To determine the 99th percentile of aCL and anti-β2GPI in healthy volunteers.</p></div><div><h3>Materials and methods</h3><p>This cross-sectional study reviewed antibody titles of anticardiolipin and β2glycoprotein I (IgG and IgM by enzyme-linked immunosorbent assay) in forty-nine healthy blood donors in Medellin, Colombia. Sociodemographic and immunological variables are also assessed. Antibody titles are described in median and interquartile range and the 99th percentile was estimated.</p></div><div><h3>Results</h3><p>We analysed samples from 16 men and 33 women. We found that the upper limits of the reference range (99th percentile) of aCL and anti-β2GPI were: aCL IgM: 18.0, aCL IgG: 16.1, anti-β2GPI IgM: 16.4, and anti- β2GPI IgG: 6.9.</p></div><div><h3>Conclusions</h3><p>The upper limits obtained differ greatly from the arbitrary classification values suggested in the international guidelines, taking into account that values greater than 40 international units are usually required, and the values identified in this study are between 6.9 and 18 international units. We suggest conducting additional studies that validate cut-off points according to the percentiles explored in this work.</p></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"31 1","pages":"Pages 3-10"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141048062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jairo Cajamarca-Barón , Diana Guavita-Navarro , Ana María Gutiérrez Cura , Paula Cristina Castro Quiroga , Héctor Cubides , Ana María Arredondo , Alejandro Escobar , José Fernando Polo Nieto , Claudia Ibáñez , Adriana Rojas-Villarraga
{"title":"Frequency of Sjögren’s syndrome in patients with dry symptoms using two histopathological methods","authors":"Jairo Cajamarca-Barón , Diana Guavita-Navarro , Ana María Gutiérrez Cura , Paula Cristina Castro Quiroga , Héctor Cubides , Ana María Arredondo , Alejandro Escobar , José Fernando Polo Nieto , Claudia Ibáñez , Adriana Rojas-Villarraga","doi":"10.1016/j.rcreue.2022.03.009","DOIUrl":"10.1016/j.rcreue.2022.03.009","url":null,"abstract":"<div><h3>Introduction and objective</h3><p>The criteria for Sjögren’s syndrome (SS) classification (ACR/EULAR 2016), include labial salivary gland (LSG) biopsy using the focus score (FS). But, in some cases it continues to be based on Chisholm and Mason (CM). Our objective was to evaluate the frequency of SS in patients with dry symptoms using FS and CM and to evaluate the degree of inter and intra-observer concordance of the histopathological reading by both methods.</p></div><div><h3>Materials and methods</h3><p>Cross-sectional study design. All patients with dry symptoms and studies to perform the SS classification criteria (2016) were included. The samples were independently evaluated by two readers. Descriptive statistics was used for the calculation of SS frequency. Agreement (Cohen’s Kappa coefficient) was analysed (STATA) for each test (CM and FS). Ethics approval was obtained.</p></div><div><h3>Results</h3><p>92 patients were included. According to the 2016 criteria, SS was reported in 26.1% patients in whom FS was used and in 34.8% patients in whom CM was used. The degree of intra-observer concordance for the diagnosis of FLS was perfect and moderate-high for observers. Inter-observer agreement was substantial, with kappa values of .77 FS and .75 CM.</p></div><div><h3>Conclusions</h3><p>FS method is a more detailed and specific score that facilitates correct classification. The use of CM as a histopathological classificatory method for SS includes more patients when compared with FS. These results are of relevance to standardise the reading of LSG biopsy in specialized services attending SS patients.</p></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"31 1","pages":"Pages 29-37"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141045092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of social media use on depression in patients with ankylosing spondylitis: Results of a cross-sectional study","authors":"Sadettin Uslu , Nihan Cüzdan , İpek Türk","doi":"10.1016/j.rcreue.2022.05.004","DOIUrl":"https://doi.org/10.1016/j.rcreue.2022.05.004","url":null,"abstract":"<div><h3>Introduction</h3><p>Social media is a powerful tool in providing information and support for patients with chronic diseases. The aim was to assess the link between using social media and depression in a sample population of Turkish ankylosing spondylitis (AS) patients.</p></div><div><h3>Materials and methods</h3><p>The patients completed a self-administered questionnaire, which was designed by the authors. Their demographic data, educational status, diagnosis, and favorite social network were also recorded. The Beck Depression Inventory-IA amended (revised) (BDI-IA-Turkish) was used to screen the AS patients for depression.</p></div><div><h3>Results</h3><p>A total of 155 AS patients were included in the study. The depression scores of the patients who used the Internet (12.18<!--> <!-->±<!--> <!-->6.85) and social media (12.35<!--> <!-->±<!--> <!-->6.90) were compared with those who did not (27.19<!--> <!-->±<!--> <!-->10.51 vs. 25.20<!--> <!-->±<!--> <!-->11.66) and a significant difference (<em>p</em> <!-->≤<!--> <!-->0.001) was found. Smartphone users were in the majority (73.5%). WhatsApp was the preferred social network (66.5%), followed by Facebook (52.9%), Instagram (52.3%), Twitter (19.4%) and Pinterest (5.8%). Social media users and non-users were similar in age, gender, educational level and marital status. There were no significant differences in terms of the type and duration of social media use with depression score.</p></div><div><h3>Conclusion</h3><p>The results of this cross-sectional study confirmed that using social media can help patients with AS to cope with or be less affected by depression. Finding the most appropriate and commonly used form of social media may be an important concept for stewardship in health policies.</p></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"31 1","pages":"Pages 38-43"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141244576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}