{"title":"Association of anti-C1q antibodies, adiponectin and HLA II genotype in Colombian patients with systemic lupus erythematosus with lupus nephritis","authors":"Sebastián Molina-Ríos , Gerardo Quintana-López , Gustavo Aroca , Eduardo Egea , Antonio Iglesias-Gamarra","doi":"10.1016/j.rcreue.2022.03.006","DOIUrl":"https://doi.org/10.1016/j.rcreue.2022.03.006","url":null,"abstract":"<div><h3>Objective</h3><p>To establish associations between the development of lupus nephritis (LN) and the expression of antibodies against C1q (anti-C1q) and serum adiponectin as these biomarkers have been previously postulated to be associated with the presence of LN.</p></div><div><h3>Materials and methods</h3><p>A case–control study nested in a cohort was chosen. Patients with SLE with renal involvement were included. Measurement of antibodies against C1q, levels of adiponectin, and HLA expression DRB1 and DQB1 were evaluated. We searched for possible associations between the measured biomarkers and allelic HLA types found.</p></div><div><h3>Results</h3><p>One hundred and six patients were recruited with LN with a mean age of 35 years. Mean adiponectin levels were 16.9<!--> <!-->μg/mL, and 60% of patients presented anti-C1q positivity. HLA DRB1*0404 and DRB1*1101 are protective factors for LN (OR: .42, <em>p</em> <!-->=<!--> <!-->.0030 and OR: 0.49, <em>p</em> <!-->=<!--> <!-->.046 respectively). HLA DRB1*0701 (OR: 3.15, <em>p</em> <!-->=<!--> <!-->.0452) and DRB1*0802 (OR: 8.3, <em>p</em> <!-->=<!--> <!-->.020) are susceptibility factors for LN. There was a tendency for association between anti-C1q positivity and high levels of adiponectin with type IV LN (OR 2.3 [95% CI: 0.68–8.2] and (OR: 2.67 [95% CI: .76–9.9] respectively). There was a tendency for association between anti-C1q positivity and HLA expression DRB1*0701 (OR 2.7 [95% CI: .81–11.5]), as well as high levels of adiponectin and HLA expression DRB1*0404 (OR 3.03 [95% CI: .92–12.8]). No association was found between anti-C1q and adiponectin with the expression of HLA DRB1*1501. There was positive correlation between levels of anti-C1q and the activity index in renal biopsy.</p></div><div><h3>Conclusions</h3><p>In the Colombian population there is a tendency for association of anti-C1q with the expression of HLA DRB1*07; however, the expression of other HLA II genes known as risk factors for LN, was not associated with the expression of anti-C1q, adiponectin or any specific type of LN.</p></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"31 1","pages":"Pages 11-17"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141244590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Erika Alexandra Barroso da Silva , Lorena Vásquez Ortiz , Camila Aragón Salleg , Ignacio Briceño Balcázar , Eduardo Tuta Quintero , Ximena Urrea , Luis Gustavo Celis , Juan Pimentel
{"title":"Autoimmunity in patients with silicone breast implants: An exploratory review","authors":"Erika Alexandra Barroso da Silva , Lorena Vásquez Ortiz , Camila Aragón Salleg , Ignacio Briceño Balcázar , Eduardo Tuta Quintero , Ximena Urrea , Luis Gustavo Celis , Juan Pimentel","doi":"10.1016/j.rcreue.2022.12.004","DOIUrl":"10.1016/j.rcreue.2022.12.004","url":null,"abstract":"<div><p>Silicone breast implants are considered highly immunogenic adjuvant devices in the human body, however, the medical evidence linking the development of autoimmune diseases and Adjuvant-induced Inflammatory Autoimmunity Syndrome (ASIA) in patients using breast implants is not conclusive. In the following manuscript, an exploratory systematic review was carried out using the Scopus and PubMed databases, including analytical and descriptive observational studies with no time limit. Twenty-one articles were included, which showed that the main autoimmune diseases associated with this group of patients were undifferentiated diseases of connective tissue; most of the patients presented symptoms such as chronic fatigue, arthralgia, fever, and myalgia. The objective of this study is to synthesize and analyse the current medical literature on the frequency of rheumatological diseases concomitant with ASIA in users of silicone breast implants.</p></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"31 1","pages":"Pages 57-67"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141055293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andres Hormaza Jaramillo , Ana Arredondo , Elias Forero , Sebastian Herrera , Carlos Ochoa , Álvaro Arbeláez-Cortés , Andres Ricardo Fernández Aldana , Andrea Rodríguez
{"title":"Recommendations on the intervention of patients with rheumatological diseases by telemedicine in Colombia","authors":"Andres Hormaza Jaramillo , Ana Arredondo , Elias Forero , Sebastian Herrera , Carlos Ochoa , Álvaro Arbeláez-Cortés , Andres Ricardo Fernández Aldana , Andrea Rodríguez","doi":"10.1016/j.rcreue.2022.06.002","DOIUrl":"10.1016/j.rcreue.2022.06.002","url":null,"abstract":"<div><h3>Introduction</h3><p>Telemedicine, defined as the provision of remote health services by health professionals using Information and Communication Technologies, has been adopted in healthcare in Colombia.</p></div><div><h3>Objective</h3><p>To establish recommendations for the implementation and management of telemedicine in clinical practice for rheumatological diseases in Colombia</p></div><div><h3>Materials and methods</h3><p>The recommendations were made in 3 phases. Phase 1 was based on an extended review and a systematic review of the literature. Phase 2 consisted of the selection of attributes and components based on the extended review to delimit the framework of the recommendations using the Delphi method. In phase 3, a group of experts, based on the systematic review, the selected attributes and components, and individual experience made recommendations through a nominal group.</p></div><div><h3>Results</h3><p>The framework of recommendations comprised 9 attributes and 26 components. A group of 7 rheumatologists in 4 cities of the country was formed. The nominal group drafted the final recommendations through 3 rounds according to the recommendations with a high priority rating.</p></div><div><h3>Conclusion</h3><p>This document contains recommendations for effective telemedicine healthcare for rheumatological diseases in Colombia. To establish effective telemedicine healthcare, it is necessary to evaluate different possible forms of care, the convenience of using telemedicine according to the clinical-cultural and sociodemographic profile of the patient, the access and implementation capacity of the different technological tools, and the exhaustive analysis of the barriers and facilitators to its adoption.</p></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"31 1","pages":"Pages 68-79"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141043234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Irene Garrido Márquez, Laura Fernández Navarro, Marta Revelles Paniza
{"title":"Synovial chondromatosis in the flexor hallucis longus of the foot: A rare finding","authors":"Irene Garrido Márquez, Laura Fernández Navarro, Marta Revelles Paniza","doi":"10.1016/j.rcreue.2022.01.002","DOIUrl":"https://doi.org/10.1016/j.rcreue.2022.01.002","url":null,"abstract":"<div><p>Synovial chondromatosis is an uncommon lesion characterized by cartilaginous metaplasia of the synovial layer with the usual formation of free osteocartilaginous bodies and typically involving large joints. Location in the ankle and foot is rare and, in turn, very rare in the synovial sheath of the foot tendons. The diagnosis of this little recognized entity is of great importance because it is a progressive condition that carries a substantial risk of local recurrence. Imaging tests such as CT or MRI help to identify the characteristic findings and the exact location to guide the orthopaedic surgeon in surgery. Its definitive treatment is surgical, through complete resection of the synovium (synovectomy).</p></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"31 1","pages":"Pages 80-83"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141244575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Olexandr Kuryata , Tetiana Lysunets , Hanna Vorotilishcheva , Vadym Pashkovskyi , Viktor V. Semenov
{"title":"Atypical onset of idiopathic inflammatory myopathy sensitive to steroids under the mask of amyotrophic lateral sclerosis: A case report","authors":"Olexandr Kuryata , Tetiana Lysunets , Hanna Vorotilishcheva , Vadym Pashkovskyi , Viktor V. Semenov","doi":"10.1016/j.rcreue.2022.04.001","DOIUrl":"https://doi.org/10.1016/j.rcreue.2022.04.001","url":null,"abstract":"<div><p>Idiopathic inflammatory myopathy is a heterogeneous group of autoimmune disorders, that share some common manifestations, such as muscle weakness and elevation of serum creatine kinase. However, classification of idiopathic inflammatory myopathy into an existing clinical subtype is not always possible. The case is a 25-year-old male with an unrecognized form of idiopathic inflammatory myopathy, the onset of which resembled amyotrophic lateral sclerosis. The paper includes differential diagnosis with amyotrophic lateral sclerosis and congenital myopathies, and response to corticosteroid therapy.</p></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"31 1","pages":"Pages 93-96"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141244577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juan Camilo Cadavid Usuga , Mónica Ortiz Pérez , Marcos Restrepo Arango , Ana María Montufar Pantoja
{"title":"Sarcoidosis diagnosis based on ocular involvement. Case report","authors":"Juan Camilo Cadavid Usuga , Mónica Ortiz Pérez , Marcos Restrepo Arango , Ana María Montufar Pantoja","doi":"10.1016/j.rcreue.2022.03.008","DOIUrl":"10.1016/j.rcreue.2022.03.008","url":null,"abstract":"<div><p>Sarcoidosis is a multisystemic disease of unknown cause, secondary to a genetically determined immune reaction triggered by environmental factors, which leads to the formation of non-caseating granulomas. Ocular involvement is the second most frequent after pulmonary involvement. The most common finding is anterior granulomatous uveitis, but posterior uveitis, retinal peri-phlebitis, chorioretinitis, conjunctivitis, scleritis and optic neuritis can also be seen. We describe the case of a pediatric patient with long-standing multisystem involvement disease, in whom the demonstration of non-caseating granulomas in the conjunctival biopsy allowed a presumptive diagnosis of sarcoidosis.</p></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"31 1","pages":"Pages 88-92"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140766581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diana Carolina Quintero-González , Andrés Felipe Cardona-Cardona , Adriana Lucía Vanegas-García , Carlos Horacio Muñoz-Vahos , Gloria Vásquez , Luis Alonso González-Naranjo
{"title":"Cryptococcus neoformans arthritis in a patient with systemic lupus erythematosus: A case report","authors":"Diana Carolina Quintero-González , Andrés Felipe Cardona-Cardona , Adriana Lucía Vanegas-García , Carlos Horacio Muñoz-Vahos , Gloria Vásquez , Luis Alonso González-Naranjo","doi":"10.1016/j.rcreue.2022.04.003","DOIUrl":"10.1016/j.rcreue.2022.04.003","url":null,"abstract":"<div><p><em>Cryptococcus neoformans</em> is the leading causal agent of invasive fungal infections in patients with systemic lupus erythematosus, frequently compromising the central nervous system and the lung. The infection develops during the first two years after diagnosis in patients with active disease, and the main risk factors are glucocorticoids, especially the cumulative dose, and lymphopenia. Mortality is high, exceeding 50%. We present the case of a man with active systemic lupus erythematosus who was admitted due to fever, arthritis, tenosynovitis, and purpura in whom disseminated <em>C. neoformans</em> infection was documented by initial isolation in blood and synovial fluid. Subsequently, he developed central nervous system symptoms like headache and nuchal rigidity that responded to induction treatment with amphotericin and flucytosine, and the manifestations resolved. Although joint and periarticular involvement by <em>C. neoformans</em> is infrequent, these are foci to consider in the approach to patients with lupus and suspected invasive fungal infection.</p></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"31 1","pages":"Pages 97-102"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141052067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The role of social media assessing mental health in rheumatology","authors":"Wilson Bautista-Molano","doi":"10.1016/j.rcreue.2024.03.001","DOIUrl":"https://doi.org/10.1016/j.rcreue.2024.03.001","url":null,"abstract":"","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"31 1","pages":"Pages 1-2"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141244589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}