Revista Colombiana de Reumatología (English Edition)最新文献

{"title":"Growing up with juvenile idiopathic arthritis: Social issues","authors":"Sirine Miri ,&nbsp;Hanene Lassoued Ferjani ,&nbsp;Dorra Ben Nessib ,&nbsp;Fatma Majdoub ,&nbsp;Dhia Kaffel ,&nbsp;Kaouther Maatallah ,&nbsp;Wafa Hamdi","doi":"10.1016/j.rcreue.2023.08.003","DOIUrl":"10.1016/j.rcreue.2023.08.003","url":null,"abstract":"<div><h3>Introduction</h3><div>Juvenile idiopathic arthritis is a chronic inflammatory condition interfering with daily activities, social integration, and school attendance in children because of pain and joint inflammation during disease flares. Online resources might help children with JIA improve their social interactions and enhance their knowledge about their disease and the available therapeutic strategies.</div></div><div><h3>Objective</h3><div>This study aims to reveal the social issues encountered by teenagers prone to JIA and determine their perception of the impact of social media on their daily life.</div></div><div><h3>Material and methods</h3><div>We conducted this study using inductive qualitative methods to describe the sociocultural perception and experience of adolescents with JIA aged between 8 and 16 years.</div></div><div><h3>Results</h3><div>Individual interviews were held with 22 adolescents diagnosed with JIA. Fifty-two percent felt like outcasts and rejected by their peers because of their illness. Most of the participants expressed a need for their friends to be informed about their JIA diagnosis. Twenty-two-point-seven percent stated that they played sports for more than 5<!--> <!-->h a week. A total of 31.8% found their physical performance was not affected by their disease. Ninety-seven of the participants confirmed that they use social media on average 3<!--> <!-->h a day. YouTube and Facebook were ranked respectively as the first and the second preferred platforms. Seventeen percent of the children viewed these platforms as positive and helpful in dealing with JIA, especially by taking their minds off the pain, dealing with the stress resulting from the lack of mobility, and facilitating interactions with others.</div></div><div><h3>Conclusion</h3><div>Social integration in children with JIA is still challenging. Social media is helpful in managing JIA and improving social interactions, and in gaining useful information.</div></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"31 4","pages":"Pages 452-456"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142533852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design and implementation of clinical care centres for spondyloarthritis. A benchmark care and disease model in chronic pathologies","authors":"Wilson Bautista-Molano ,&nbsp;Paul Méndez-Patarroyo ,&nbsp;Helbert Orlando Arévalo Roa ,&nbsp;Gerardo Quintana-López","doi":"10.1016/j.rcreue.2024.08.003","DOIUrl":"10.1016/j.rcreue.2024.08.003","url":null,"abstract":"<div><h3>Introduction</h3><div>Spondyloarthritis (SpA) is a musculoskeletal disease presenting with phenotypic clinical manifestations, integrating a set of interrelated inflammatory conditions, which share immunogenetic, epidemiological, and therapeutic characteristics.</div></div><div><h3>Objective</h3><div>to do a reflection exercise through the experience of designing and implementing a clinical care center for spondyloarthropathies, from the administrative and clinical perspective to the implications in decision making and impact on the different indicators related to efficiencies and safety of the services included in the model.</div></div><div><h3>Results</h3><div>In clinical practice, the reality of the care process in patients diagnosed with SpA represents an area of ​​opportunity in multiple aspects. The fragmentation of clinical care and the heterogeneous flow of the patient in the care pathway, are associated with suboptimal and undesired clinical outcomes. Several aspects highlight the reality of patients with SpA in the national scenario, which -to a certain extent- could reflect what is observed in other Latin American countries. SpA represents a very significant burden for society and for individuals affected by this condition. Comprehensive assessment of the burden of disease from the perspective of the clinician and the patient is important, in order to support decisions related to treatment and comprehensive management of this condition. The improvement in health outcomes and the reduction in the cost of chronic inflammatory diseases, such as SpA, are the main advantages of implementing a care model in specialized centres integrating a multidisciplinary team.</div></div><div><h3>Conclusion</h3><div>This is an opportunity to include the perspective of individuals affected by this condition, seeking integration between an informed patient and a highly qualified multidisciplinary care team in the comprehensive management of patients with SpA.</div></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"31 4","pages":"Pages 511-516"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142533800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inadequate sleep as a limiting factor in achieving remission in patients with rheumatoid arthritis","authors":"Amarilis J. Pérez De Jesus ,&nbsp;Nahir S. Pérez Soto ,&nbsp;Miguel A. Vázquez Padua","doi":"10.1016/j.rcreue.2023.05.005","DOIUrl":"10.1016/j.rcreue.2023.05.005","url":null,"abstract":"<div><h3>Introduction</h3><div>Good sleep has a restorative effect at the cellular level and helps maintain the body's homeostasis.</div></div><div><h3>Objectives</h3><div>Given our clinical experiences, we propose that sleep quality should be evaluated in patients with rheumatoid arthritis. Poor sleep quality should be considered as a factor that may impact clinical outcomes in patients with rheumatoid arthritis.</div></div><div><h3>Materials and methods</h3><div>We researched medical literature on clinical and physiological pathways associated with sleep quality.</div></div><div><h3>Results</h3><div>There is evidence that interleukin-6 and tumor necrosis factor have a role in inflammatory and immune imbalance as well as in sleep disturbance in patients with rheumatoid arthritis, which leads to the chronic inflammatory process seen in these patients. Most patients with rheumatoid arthritis report sleep problems, be it insomnia or other complaints of non-refreshing sleep. Lack of sleep or poor sleep patterns in these patients further compromise their quality of life. In patients with RA, aetiologies such as restless leg syndrome (RLS), sleep apnoea syndrome, and Temporomandibular Joint Dysfunction (TMJ) syndromes might contribute to sleep disturbances. This lack of restful sleep might limit our goal, as treating physicians, to achieve remission states in these patients.</div></div><div><h3>Conclusions</h3><div>It is our opinion that sleep quality evaluation must be addressed, monitored, and treated as part of the management of patients with RA. Bad sleep adds an additional burden to disease activity in patients with RA, besides, it limits patients’ possibility of achieving disease remission.</div></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"31 4","pages":"Pages 517-522"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142533801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of clinical outcomes in patients with rheumatoid arthritis from the patient's perspective: a narrative review of the literature","authors":"Juliana Gil Samper ,&nbsp;Felipe García Durán ,&nbsp;Wilson Bautista Molano","doi":"10.1016/j.rcreue.2024.09.002","DOIUrl":"10.1016/j.rcreue.2024.09.002","url":null,"abstract":"<div><h3>Introduction</h3><div>The evaluation of clinical outcomes in rheumatoid arthritis patients, including the patient's perspective, allows the inclusion of the patient's perspective in clinical decision-making using instruments designed for this purpose.</div></div><div><h3>Objective</h3><div>To identify and describe the instruments validated in Spanish to evaluate clinical outcomes in rheumatoid arthritis in daily clinical practice and from the patient's perspective, including disease activity, functionality, impact of the disease, adherence to treatment and quality of life.</div></div><div><h3>Materials and methods</h3><div>A review of the literature in various databases (PubMed, Scopus, Bireme, Scielo) was conducted looking for questionnaires that evaluate clinical outcomes in rheumatoid arthritis patients, including those with a validated Spanish translation that allow self-assessment of the disease by the patient and clinical monitoring.</div></div><div><h3>Results</h3><div>Fifteen questionnaires were identified and selected that met the inclusion criteria. Four instruments were found that evaluate quality of life, three that evaluate functionality, four that evaluate disease impact, one that evaluate disease activity, and three that evaluate adherence to treatment.</div></div><div><h3>Conclusion</h3><div>Questionnaires and scales that evaluate rheumatoid arthritis allow a clinical approach to the evolution of the disease as perceived and reported by the patients, optimizing clinical follow up. Implementation of these tools in clinical decision making allows for an improvement in quality of care of patient with this condition.</div></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"31 4","pages":"Pages 489-497"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142533798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"About autoimmunity and COVID-19 in pediatrics","authors":"Adriana Diaz-Maldonado","doi":"10.1016/j.rcreue.2024.09.003","DOIUrl":"10.1016/j.rcreue.2024.09.003","url":null,"abstract":"","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"31 4","pages":"Pages 433-434"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142533802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Autoimmunity in paediatric patients from a region of Colombia, after a SARS-CoV2 peak","authors":"Valeria Camila Restrepo Arias","doi":"10.1016/j.rcreue.2024.08.005","DOIUrl":"10.1016/j.rcreue.2024.08.005","url":null,"abstract":"<div><h3>Introduction</h3><div>With the onset of the 2019 coronavirus pandemic, there was an increase in the number of reported cases of autoimmune manifestations in the midst of the disease and new cases of autoimmunity after infection.</div></div><div><h3>Objective</h3><div>To correlate the rate of positive tests of SARS-CoV-2 with the rate of new diagnoses of autoimmune disease in paediatric patients of the department of Huila (Colombia), between March 2020 and September 2021.</div></div><div><h3>Methods</h3><div>The socio-demographic characterization of the subjects diagnosed with autoimmune disease and of the cases of SARS-CoV-2 was performed; an analysis of the monthly trend of events was performed and a correlation model was applied between the rate of SARS-CoV-2 diagnosis and the rate of autoimmune diseases during the study period.</div></div><div><h3>Results</h3><div>94 cases of autoimmune disease were diagnosed, with an average age of 8.3 years, most were girls and belonged to the urban area and the subsidized regimen, and immune thrombocytopenic purpura was the most common diagnosis. In addition, 4303 cases of SARS-CoV-2 were detected, mostly adolescents, from urban areas and the contributory system. Finally, it was evidenced that the highest rate of autoimmune disease was reported just after the highest peak of SARS-CoV-2.</div></div><div><h3>Conclusions</h3><div>This study did not show a statistical correlation between the rate of SARS-CoV-2 and the rate of diagnoses of autoimmune disease; however, it showed an enormous peak of autoimmunity after the highest peak of infection in paediatric patients of the department during the first eighteen months of the pandemic.</div></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"31 4","pages":"Pages 442-451"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142533803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of FACIT-fatigue in Spanish-speaking patients with rheumatoid arthritis","authors":"Samantha Rodríguez-Muguruza ,&nbsp;Sonia Castro ,&nbsp;María José Poveda ,&nbsp;Silvia Paredes ,&nbsp;Delia Taverner ,&nbsp;Oliver Valero ,&nbsp;Ramon Fontova","doi":"10.1016/j.rcreue.2023.05.006","DOIUrl":"10.1016/j.rcreue.2023.05.006","url":null,"abstract":"<div><h3>Introduction</h3><div>Fatigue is a frequent symptom in patients with rheumatoid arthritis<span> (RA). The Functional Assessment of Chronic illnesses Therapy-Fatigue (FACIT-F) is an instrument that assesses self-reported fatigue and was validated for measuring fatigue in RA.</span></div></div><div><h3>Objective</h3><div>The aim of this study was to validate the FACIT-F for use in Spanish-speaking RA patients.</div></div><div><h3>Materials and methods</h3><div>Cross-sectional, multicentre study. We included patients (n = 192) with RA diagnosis from two hospitals. Exploratory and confirmatory analyses were conducted. Construct validity<span> and internal consistency were evaluated.</span></div></div><div><h3>Results</h3><div>FACIT-F showed high internal consistency (Alpha = .87, Omega = .93). Analysis of the main components showed a single factor, which explained 62% of the variance. The confirmatory factor analysis<span> showed a satisfactory fit of the model. We found a correlation between FACIT–F, VAS fatigue (−.72 p-value &lt;,001), and BRAF-MDQ (−.81 p-value &lt;.001).</span></div></div><div><h3>Conclusion</h3><div>FACIT-F is a valid instrument with a high internal consistency for measuring fatigue in clinical practice and research in Spanish-speaking patients with RA.</div></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"31 4","pages":"Pages 435-441"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141853162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Central tolerance in T cells, what’s new?","authors":"Alex Imbachí-Salamanca ,&nbsp;Gloria Vásquez","doi":"10.1016/j.rcreue.2024.09.001","DOIUrl":"10.1016/j.rcreue.2024.09.001","url":null,"abstract":"<div><h3>Introduction</h3><div>Random somatic recombination of T cell receptors facilitates the variability of response to foreign antigens. Then, central tolerance occurs, a mechanism designed to avoid exit of autoreactive T cells from the thymus. However, failures in this process can induce the appearance of autoimmunity.</div></div><div><h3>Materials and methods</h3><div>This narrative review was conducted through a literature search focused on describing relevant and recent concepts of central tolerance of T cells.</div></div><div><h3>Results</h3><div>Multiple cell groups are part of the thymic microenvironment, among them, thymic epithelial cells are responsible for directing development of thymocytes, especially medullary thymic epithelial cells that direct the negative selection process.</div></div><div><h3>Conclusions</h3><div>Factors that affect thymocytes, the thymic microenvironment, or interaction between them, can lead to development of immunodeficiencies and/or autoimmunity.</div></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"31 4","pages":"Pages 480-488"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142533797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Balancing inflammation and adverse effects of glucocorticoids in clinical practice","authors":"Juan Sebastián Peinado-Acevedo ,&nbsp;Tatiana Rivera-Bustamante ,&nbsp;Jairo Rivera ,&nbsp;Yeison Santamaría-Alza","doi":"10.1016/j.rcreue.2023.08.004","DOIUrl":"10.1016/j.rcreue.2023.08.004","url":null,"abstract":"<div><div>Corticosteroids play a vital role in enabling the body to tolerate stressful situations and regulate the inflammatory process. Excessive or persistent inflammation can lead to tissue damage and the development of diseases. Glucocorticoids are crucial in modulating the impact of inflammatory disorders, such as allergies, autoimmune diseases, and sepsis. These disorders can be life-threatening and benefit from glucocorticoid administration. Natural and synthetic glucocorticoids are utilized for the diagnosis and treatment of adrenal function disorders and various inflammatory, immune, and neoplastic conditions. The discovery of glucocorticoids is a testament to the ingenuity and collaboration of researchers. For over 70 years, glucocorticoids have revolutionized medicine and are widely employed in various medical conditions. This article provides a comprehensive review of the critical considerations for the clinical application of glucocorticoids, aiming to strike a balance between their benefits and potential risks. Understanding its history, chemical structure, pharmacology, and mechanisms of action provides the foundation for achieving proper use of this type of medication.</div></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"31 4","pages":"Pages 498-510"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142533799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparison of core muscle endurance of females with fibromyalgia versus healthy females: An observational study","authors":"Dewanshu Sindwani,&nbsp;Manjyot Kaur","doi":"10.1016/j.rcreue.2024.08.001","DOIUrl":"10.1016/j.rcreue.2024.08.001","url":null,"abstract":"<div><h3>Introduction</h3><div>Despite the numerous benefits of core muscle strengthening in improving symptoms of fibromyalgia (FM), limited studies have quantified core muscle function in FM patients.</div></div><div><h3>Objective</h3><div>To compare the core muscle endurance of FM females with age-matched healthy females and determine whether a correlation exists between core muscle endurance and FM severity.</div></div><div><h3>Materials and methods</h3><div>Pre-diagnosed female FM patients (<em>n</em> <!-->=<!--> <!-->7) and age-matched healthy females (<em>n</em> <!-->=<!--> <!-->19) were assessed using McGill's core endurance tests in four positions – flexion, extension, and bilateral side-bridge. The longest contraction holding time (in seconds) in each position was noted and compared in both groups. Additionally, patient-reported Fibromyalgia Impact Questionnaire (FIQ) scores were obtained to determine disease severity.</div></div><div><h3>Results</h3><div>The mean holding time for trunk extensors (26.14<!--> <!-->±<!--> <!-->7.7<!--> <!-->s), right lateral flexors (20.14<!--> <!-->±<!--> <!-->8.3<!--> <!-->s), and left lateral flexors (20.86<!--> <!-->±<!--> <!-->5.3<!--> <!-->s) was significantly lower in the FM females than the healthy females (trunk extensors<!--> <!-->=<!--> <!-->55.21<!--> <!-->±<!--> <!-->17.1<!--> <!-->s; right lateral flexors<!--> <!-->=<!--> <!-->36.05<!--> <!-->±<!--> <!-->13.2<!--> <!-->s; left lateral flexors<!--> <!-->=<!--> <!-->35.11<!--> <!-->±<!--> <!-->13.8<!--> <!-->s). The endurance of trunk flexors was statistically similar in both groups (FM females<!--> <!-->=<!--> <!-->52.14<!--> <!-->±<!--> <!-->27.9<!--> <!-->s; healthy females<!--> <!-->=<!--> <!-->74.37<!--> <!-->±<!--> <!-->37.7<!--> <!-->s). Lastly, core muscle endurance was not correlated with the FIQ scores in FM patients (<em>p</em> <!-->&gt;<!--> <!-->0.05).</div></div><div><h3>Conclusion</h3><div>The results of this preliminary study revealed that core extensor and lateral flexor endurance in FM females was lower than their healthy female counterparts. Larger sample studies are needed to further substantiate our findings.</div></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"31 4","pages":"Pages 473-479"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142533796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}