Revista Colombiana de Reumatología (English Edition)最新文献

{"title":"Renal ultrasound in rheumatic diseases","authors":"Fabiola Pazos-Pérez,&nbsp;Carlos Enrique Méndez-Landa,&nbsp;María Ines Gil-Arredondo,&nbsp;Yessyca López-Cabrera,&nbsp;Estefanía Garduño-Hernández,&nbsp;Francisco Román Soto-Zuñiga,&nbsp;Ivan Jese Casas-Romero,&nbsp;Jesús Iván Lara-Prado,&nbsp;Dulce Paola Grajales-García","doi":"10.1016/j.rcreue.2026.504931","DOIUrl":"10.1016/j.rcreue.2026.504931","url":null,"abstract":"<div><div>Ultrasound (US) is the imaging study of choice in patients with systemic autoimmune rheumatic diseases with clinical suspicion of kidney damage, as it requires no radiation, is non-invasive, and provides real-time imaging. It has become more accessible, and currently, bedside US can be performed with portable devices. US allows evaluation of the structural (shape and size) and functional (perfusion and permeability) aspects of the kidneys, which are particularly important as rheumatological diseases progress. There are no specific ultrasonographic findings in these diseases; consequently, interpretation often depends on clinical correlation. This review describes the most frequent indications and findings in conventional USG and Doppler US in various systemic rheumatological diseases.</div></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"33 3","pages":"Article 504931"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149096842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep quality in rheumatoid arthritis: A cross sectional study","authors":"Sonia Rekik,&nbsp;Faïza Ben Messaoud,&nbsp;Safa Rahmouni,&nbsp;Khaoula Zouaoui,&nbsp;Lobna Ben Ammar,&nbsp;Maïssa Abbes,&nbsp;Soumaya Boussaid,&nbsp;Hela Sahli","doi":"10.1016/j.rcreue.2026.102184","DOIUrl":"10.1016/j.rcreue.2026.102184","url":null,"abstract":"<div><h3>Introduction</h3><div>While numerous studies have examined the physical consequences of rheumatoid arthritis (RA), its impact on sleep quality remains relatively understudied.</div></div><div><h3>Objective</h3><div>This study aims to specifically assess the effect of RA on patients’ sleep quality.</div></div><div><h3>Materials and methods</h3><div>We conducted a cross-sectional study. Patient characteristics were assessed. The patients’ sleep quality was assessed using the Medical Outcomes Study Sleep Scale (MOS-Sleep scale) in its validated Arabic version.</div></div><div><h3>Results</h3><div>the study included <em>n</em> <!-->=<!--> <!-->49 patients with RA. Their mean age was 54.1±12.06 years [24–83]. The mean diagnostic delay was 2.35 years [0.5–13]. The RA was erosive in 46 cases (93.8%), two patients (4.1%) had atlantoaxial subluxation, and coxitis was noted in four cases (8.2%). A longer diagnostic delay was associated with a higher sleep problem index score. A significant positive association was found between VAS pain and all sleep disturbance scores (<em>p</em> <!-->=<!--> <!-->0.00 and <em>r</em> <!-->=<!--> <!-->0.518). The presence of comorbidities was associated with a higher index (<em>p</em> <!-->=<!--> <!-->0.03). This was also true in case of coxitis and/or atlantoaxial subluxation (<em>p</em> <!-->=<!--> <!-->0.03). For therapeutic management, we did not find a statistically significant association between the use of NSAIDs or corticosteroids, or methotrexate (MTX), and the sleep problem index. However, weekly dosage of MTX was positively correlated with the sleep problem index (<em>p</em> <!-->=<!--> <!-->0.03, <em>r</em> <!-->=<!--> <!-->0.358). The multivariate analysis found global patient assessment (GPA) (<em>p</em> <!-->=<!--> <!-->0.000), presence of comorbidities (<em>p</em> <!-->=<!--> <!-->0.007), and presence of atlantoaxial subluxation and/or coxitis (<em>p</em> <!-->=<!--> <!-->0.05) were significant factors influencing sleep quality.</div></div><div><h3>Conclusion</h3><div>diagnostic delay and the global management of RA patients, including co-morbidities could impact sleep quality. Therefore, early treatment and holistic management of patients are necessary.</div></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"33 3","pages":"Article 102184"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149096923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Update on ultrasound in crystal arthropathies","authors":"Alessandro Lucia,&nbsp;Jairo Cajamarca,&nbsp;Rodolfo Fabbri,&nbsp;Georgios Filippou,&nbsp;Mario Díaz","doi":"10.1016/j.rcreue.2026.504875","DOIUrl":"10.1016/j.rcreue.2026.504875","url":null,"abstract":"<div><div>Crystal-induced arthropathies (CIAs), which include gout, calcium pyrophosphate deposition (CPPD) disease, and basic calcium phosphate deposition (BCPD) disease, are prevalent yet intricate conditions characterized by the deposition of specific crystal types in joints and periarticular tissues. While synovial fluid analysis using polarized light microscopy remains a cornerstone for diagnosis, musculoskeletal ultrasound (US) has emerged as a highly sensitive, non-invasive diagnostic modality for the evaluation of CIAs. The capability of ultrasound to produce real-time, high-resolution, and dynamic imaging positions it as an invaluable tool in the assessment and management of these disorders. In recent years, US has been rigorously studied and validated for its diagnostic accuracy and reliability, particularly in gout and CPPD. Its sensitivity in detecting features such as the double contour sign in gout and CPP aggregates in fibrocartilage and hyaline cartilage in case of CPPD has been well-documented. Conversely, while US is frequently utilized in BCPD for diagnostic purposes, monitoring disease progression, and guiding imaging-assisted procedures, a robust and comprehensive validation of its utility in this condition remains lacking. This review underscores the role of ultrasound in the diagnosis and management of CIAs, with a focus on its applications in gout, CPPD, and BCPD. It discusses its clinical benefits and the current evidence supporting its use. Additionally, the review highlights gaps in research, particularly for BCPD, and outlines future directions to enhance the integration of ultrasound in the diagnostic and therapeutic landscape of CIAs.</div></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"33 3","pages":"Article 504875"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149096926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the potential link between vitamin D receptor Cdx2 gene polymorphism and rheumatoid arthritis in female patients: a study in Erbil, Kurdistan Region-Iraq","authors":"Raghda R. Qadir,&nbsp;Bushra H. Shnawa,&nbsp;Mukhtar H. Ahmed","doi":"10.1016/j.rcreue.2026.102179","DOIUrl":"10.1016/j.rcreue.2026.102179","url":null,"abstract":"<div><h3>Introduction</h3><div>In recent decades, vitamin D has been extensively researched in relation to several autoimmune diseases, including Rheumatoid Arthritis (RA).</div></div><div><h3>Objective</h3><div>The primary objective of this study is to investigate the relationship between RA and polymorphism in vitamin D receptor gene Cdx2 in a sample of women.</div></div><div><h3>Methods</h3><div>Eighty females (60 with RA and 20 controls) participated in this case–control investigation. The Cdx2 single nucleotide polymorphism (SNP) of the VDR gene was genotyped using the tetra-primer amplification refractory mutation system-polymerase chain reaction technique (ARMS-PCR).</div></div><div><h3>Results</h3><div>The current study found that 51 RA patients have the heterozygous GA genotype of the Cdx2 polymorphism despite non-significant values. Although the present findings showed no significant association between Cdx2 gene polymorphism and the risk of RA, this genotype still represents the majority among the study's RA patients. Moreover, vitamin D3 serum was significantly lower in RA with the GA genotype compared to healthy controls (HC) with a similar genotype (<em>p</em> = .0002). Also, RA patients with heterozygote GA genotype for Cdx2 had a relatively lower mean VD3 serum level than those with homozygote GG genotype.</div></div><div><h3>Conclusion</h3><div>The novelty of this study is to discover the probable association of Vitamin D receptor, caudal-related homeobox 2 (VDR-Cdx2) polymorphism with RA in the given study group for the first time in our society using a tetra primer ARMS-PCR. Additionally, the tetra-primer ARMS-PCR technique is simple, reliable, and cost-effective, making it a potentially valuable alternative to Restriction Fragment Length Polymorphism-Polymerase Chain Reaction (RFLP-PCR) for (SNP) genotyping.</div></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"33 3","pages":"Article 102179"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149096916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Update on ultrasound in spondyloarthritis and psoriatic arthritis","authors":"Sebastián Herrera Uribe ,&nbsp;Erika Marcela Padilla Martínez ,&nbsp;Diana Padilla-Ortiz ,&nbsp;Emilio Filippucci","doi":"10.1016/j.rcreue.2026.504871","DOIUrl":"10.1016/j.rcreue.2026.504871","url":null,"abstract":"<div><div>Musculoskeletal ultrasound has emerged as an important imaging modality in the diagnosis and management of spondyloarthritis and psoriatic disease offering detailed insights that help guide clinical decision-making and optimizing patient care. We aim to review its utility in diagnosis, treatment, prognosis and special situations in both diseases.</div></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"33 2","pages":"Article 504871"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148193384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Colombian guidelines on osteoporosis: Towards a more comprehensive and preventive care","authors":"Adriana Medina","doi":"10.1016/j.rcreue.2026.504915","DOIUrl":"10.1016/j.rcreue.2026.504915","url":null,"abstract":"","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"33 2","pages":"Article 504915"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148193328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ANCA-associated vasculitis with severe pulmonary involvement as an adverse effect of propylthiouracil: A case report","authors":"José S. Cortés ,&nbsp;Javier Alejandro Correa ,&nbsp;Wilder Carvajal ,&nbsp;Wilmer Aponte ,&nbsp;Luis Javier Cajas","doi":"10.1016/j.rcreue.2026.504866","DOIUrl":"10.1016/j.rcreue.2026.504866","url":null,"abstract":"<div><h3>Introduction</h3><div>Propylthiouracil (PTU) is used to treat Graves' disease and has been reported to induce antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV).</div></div><div><h3>Case report</h3><div>A 54-year-old woman with Graves' disease developed PTU-associated AAV, manifested by diffuse alveolar hemorrhage complicated by pneumonia and pleural effusion. As part of her treatment, she received methylprednisolone, prednisolone, and rituximab. The patient showed remarkable pulmonary recovery at three-month follow-up.</div></div><div><h3>Conclusions</h3><div>This case highlights the importance of early recognition of PTU-induced AAV and the progression of a severe pulmonary complication.</div></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"33 2","pages":"Article 504866"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148193388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polyarteritis nodosa: A rare complication of HIV infection, a case report","authors":"Jennifer Delgadillo Velásquez ,&nbsp;Julia Recalde-Reyes ,&nbsp;Oscar Rodrigo Vargas ,&nbsp;Luis Javier Cajas Santana","doi":"10.1016/j.rcreue.2026.504867","DOIUrl":"10.1016/j.rcreue.2026.504867","url":null,"abstract":"<div><h3>Introduction</h3><div>HIV-associated vasculitis is rare. Cases involving small and medium-sized vessels have been reported, usually in the form of polyarteritis nodosa (PAN). Diagnosis is challenging, and treatment is even more challenging in immunocompromised patients.</div></div><div><h3>Case summary</h3><div>We describe the case of a 42-year-old patient with a history of HIV infection who was presented with skin lesions and critical ischemia in the lower limbs. Diagnostic studies, treatment, and outcome are detailed.</div></div><div><h3>Conclusion</h3><div>Vasculitis are common clinical entities, but their association with HIV infection is rare. Their presentation has become increasingly rare since the introduction of antiretroviral therapy, with very few cases described in the literature. Their appearance is a cause of significant morbidity and requires multidisciplinary and careful management to minimize risks.</div></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"33 2","pages":"Article 504867"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148193397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From traditional to digital: Artificial intelligence, transforming ultrasound in rheumatology","authors":"Diego Javier Martínez Lozano ,&nbsp;Yimy F. Medina ,&nbsp;Adriana Beltrán-Ostos ,&nbsp;Carlos A. Guillén-Astete","doi":"10.1016/j.rcreue.2026.504872","DOIUrl":"10.1016/j.rcreue.2026.504872","url":null,"abstract":"<div><div>The use of artificial intelligence (AI) in musculoskeletal ultrasound has grown significantly in recent years, particularly in rheumatology, where standardization of diagnostic accuracy and image acquisition is essential. This article provides a narrative review of the available scientific literature on AI applications in musculoskeletal ultrasound, focusing on the recent advances in machine learning and deep learning algorithms. Sixteen studies published between 2020 and 2023 were reviewed, applying AI to anatomical segmentation and diagnostic prediction in musculoskeletal conditions, such as rheumatoid arthritis and other inflammatory diseases. Most of the reviewed studies employed deep learning algorithms to enhance the diagnostic accuracy and reduce operator-dependent variability. However, a common limitation across studies is the lack of external validation, indicating that future research should focus on confirming the generalizability of these models to larger populations and diverse clinical settings. Despite this limitation, the results suggest that AI has the potential to optimize clinical decision making and improve patient care in the context of musculoskeletal ultrasound in rheumatology.</div></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"33 2","pages":"Article 504872"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148193383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Salivary gland ultrasound: From standard protocols to clinical impact in rheumatology","authors":"Karen Tatiana Gualdrón-Chaparro ,&nbsp;Juan David Urriago-Gil ,&nbsp;José Santiago Cortés Guzmán ,&nbsp;Sofia C. Barreira ,&nbsp;Santiago Bernal-Macías","doi":"10.1016/j.rcreue.2026.504873","DOIUrl":"10.1016/j.rcreue.2026.504873","url":null,"abstract":"<div><div>Ultrasound of the salivary and parotid glands has become a valuable tool in rheumatology, especially in the assessment of patients with sicca symptoms, including those with Sjögren's syndrome (SjS). This imaging modality offers a non-invasive approach with proven sensitivity for diagnosis, disease differentiation, and treatment response assessment. This article presents a comprehensive literature review on the use of salivary gland ultrasound (SGUS) in various conditions associated with sicca symptoms, focusing on its application in SjS and other diseases like sarcoidosis, IgG4-related disease (IgG4-RD), and amyloidosis. We summarize the SGUS protocol, normal and pathological findings, and the OMERACT scoring system that standardizes SGUS interpretation. Studies show SGUS provides significant diagnostic support in SjS, with potential utility in assessing other connective tissue and infiltrative diseases, although its role in non-SjS conditions remains under study. Further validation is needed to define its role in clinical algorithms, especially in non-SjS etiologies, and to establish its prognostic value in treatment response. SGUS may improve the sensitivity and specificity of established diagnostic criteria, though it does not entirely replace biopsy in certain cases. Future research should further validate SGUS in diverse rheumatic conditions.</div></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"33 2","pages":"Article 504873"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148193477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}