中华核医学与分子影像杂志最新文献

{"title":"Treatment response of differentiated thyroid carcinoma with negative preablative stimulated thyroglobulin and iodine-positive lymph node after the first radioablation and influence factors analysis","authors":"Chenghui Lu, Jiao Li, Xinfeng Liu, Guoqiang Wang, Zenghua Wang","doi":"10.3760/CMA.J.ISSN.2095-2848.2020.01.005","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.2095-2848.2020.01.005","url":null,"abstract":"Objective \u0000To investigate the response to 131I therapy and to explore the influence factors in postoperative differentiated thyroid carcinoma (DTC) patients with negative preablative stimulated thyroglobulin (psTg) and iodine-positive lymph node after the first radioablation. \u0000 \u0000 \u0000Methods \u0000From May 2016 to October 2018, 108 DTC patients (28 males, 80 females, age: (45.7±10.4) years) with negative psTg who underwent 131I treatment for the first time in the Affiliated Hospital of Qingdao University were retrospectively enrolled. All patients had iodine-positive lymph nodes, which were showed by SPECT/CT imaging 5-6 d after 131I treatment. The treatment response was evaluated at 6-24 month after 131I treatment. Patients were divided into excellent response (ER) group and non-excellent response (non-ER) group according to the response to the first 131I treatment. Independent-sample t test, χ2 test and Mann-Whitney U test were used to analyze differences of factors (e.g. age, gender, extraglandular infiltration) between the 2 groups, and then multivariate logistic regression was performed to find the influence factors for treatment response. The receiver operating characteristic (ROC) curve was employed to evaluate the predictive value of the iodine-positive lymph node size in 131I treatment response. \u0000 \u0000 \u0000Results \u0000A total of 82 patients (75.93%, 82/108) achieved ER, and 26 (24.07%, 26/108) was non-ER patients. There were significant differences in age (t=-2.540, P=0.016), extraglandular infiltration (χ2=5.764, P=0.016), T stage (χ2=19.857, P<0.001), N stage (χ2=14.145, P=0.001), risk stratification of recurrence (χ2=11.487, P=0.003), ultrasound results before 131I treatment (χ2=44.819, P<0.001), dose of the first 131I treatment (U=780.0, P=0.018), size (long diameter) of iodine-positive lymph node (U=184.0, P<0.001), and psTg level (U=776.0, P=0.037) between ER and non-ER groups. Multivariate logistic regression showed that age, size of iodine-positive lymph node and ultrasound results before 131I treatment were closely related to 131I treatment response. The odds ratio (OR) values (95% CI) were 1.123 (1.025-1.231), 4.275 (1.893-9.653) and 260.86 (8.123-8 376.764), respectively. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value for non-ER were 100%(26/26), 70.73%(58/82), 77.78%(84/108), 52.00%(26/50) and 100%(58/58) respectively when the cut-off value of iodine-positive lymph node size was 5.5 mm. \u0000 \u0000 \u0000Conclusion \u0000The response of some DTC patients with negative psTg and iodine-positive lymph node after the first radioablation were non-ER. Age, ultrasound results before 131I treatment and size of iodine-positive lymph node are sensitive indicators for predicting clinical outcome in DTC patients with negative psTg and iodine-positive lymph node after the first radioablation. \u0000 \u0000 \u0000Key words: \u0000Thyroid neoplasms; Radiotherapy; Iodine radioisotopes; Thyroglobulin","PeriodicalId":10099,"journal":{"name":"中华核医学与分子影像杂志","volume":"40 1","pages":"21-26"},"PeriodicalIF":0.0,"publicationDate":"2020-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47916561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experimental study of 18F-FDG PET/CT imaging and cardiac MRI in diagnosis of radiation-induced myocardial injury in Beagle dogs","authors":"R. Yan, Jian-bo Song, Min Guo, R. Wu, Zhifang Wu, X. Hao, Xiaoshan Guo, Hua Wei, Ping Wu, Li Li, Sijin Li","doi":"10.3760/CMA.J.ISSN.2095-2848.2020.01.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.2095-2848.2020.01.006","url":null,"abstract":"Objective \u0000To investigate the value of 18F-fluorodeoxyglucose (FDG) PET/CT imaging and cardiac MRI (CMR) in the diagnosis of radiation-induced heart disease (RIHD) in Beagle models. \u0000 \u0000 \u0000Methods \u0000Twenty-four normal male Beagle dogs (1-year old) were randomly divided into control group and irradiated groups (3-month, 6-month and 12-month after radiation). The left anterior myocardium of Beagle dogs in irradiated groups was irradiated locally with a single dose of 20 Gy X-ray. Cardiac 18F-FDG PET/CT imaging and CMR were performed on all dogs, and the mean standardized uptake value (SUVmean) and the area of lesions with increased 18F-FDG uptake were obtained. After imaging examinations were finished, dogs were sacrificed and their hearts were taken out to perform Masson staining and electron microcopy. One-way analysis of variance was used for data analysis. \u0000 \u0000 \u0000Results \u0000There was basically no uptake in myocardium in control group. The myocardium showed increased uptake of 18F-FDG in the irradiated groups. The SUVmean of myocardium in 3-month, 6-month and 12-month after radiation groups and control group were 5.90±1.31, 4.66±2.21, 3.21±0.82 and 1.13±0.21, respectively (F=11.81, P<0.05). The area with increased 18F-FDG uptake in the irradiated groups decreased progressively with the prolongation of irradiation time (F=195.74, P<0.01). The reduction in myocardial perfusion and myocardial fibrosis were observed by CMR early at 6-month after irradiation. Compared with the control group, the 6-month and 12-month after radiation groups had increased end diastolic volume (EDV) and end systolic volume (ESV; F=15.479 and 16.908, both P<0.01), and decreased left ventricular ejection fraction (LVEF; F=63.715, P<0.01). The progressive aggravation of myocardial fibrosis was displayed in irradiated groups by Masson staining. The mitochondria degeneration, swelling and the count reduction in irradiated groups were observed by electron microscopy. \u0000 \u0000 \u0000Conclusions \u0000The increased 18F-FDG uptake in the irradiated myocardium may predict the risk of RIHD. 18F-FDG PET/CT imaging can detect RIHD earlier than CMR. \u0000 \u0000 \u0000Key words: \u0000Heart; Radiation injuries, experimental; Positron emission tomography; Tomography, X-ray computed; Deoxyglucose; Magnetic resonance imaging; Dogs","PeriodicalId":10099,"journal":{"name":"Chinese Journal of Nuclear Medicine and Molecular Imaging","volume":"40 1","pages":"27-31"},"PeriodicalIF":0.0,"publicationDate":"2020-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44336676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research progress of fluorescence imaging in neural localization","authors":"Shiqi Hu, Xiaofeng Huang","doi":"10.3760/CMA.J.ISSN.2095-2848.2020.01.013","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.2095-2848.2020.01.013","url":null,"abstract":"The difficulty of neural localization during operation often leads to the increased risk of nerve injury, which results in neurological dysfunction, so how to accurately locate the nerves in surgeries, such as operations for patients with recurrent parotid tumors and prostate surgery, has become one of the key factors for the success of the operation. There are many methods to locate nerves in real time during operation, among which fluorescence imaging has attracted more and more attention due to its unique advantages of high sensitivity, easy to use, low cost and no radiation. In this article, the related research progresses of fluorescence imaging in neural localization are reviewed. \u0000 \u0000 \u0000Key words: \u0000Stereotaxic techniques; Nerve; Optical imaging; Fluorescence; Trends","PeriodicalId":10099,"journal":{"name":"Chinese Journal of Nuclear Medicine and Molecular Imaging","volume":"40 1","pages":"52-55"},"PeriodicalIF":0.0,"publicationDate":"2020-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69935041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"99Tcm-ECD SPECT/CT imaging in cerebral proliferative angiopathy: a case report","authors":"Zejun Chen, Qianhuan Huang, F. Ye, Xugang Xie, Xian-ping Meng, Heng Gao","doi":"10.3760/CMA.J.ISSN.2095-2848.2020.01.009","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.2095-2848.2020.01.009","url":null,"abstract":"","PeriodicalId":10099,"journal":{"name":"中华核医学与分子影像杂志","volume":"40 1","pages":"39-40"},"PeriodicalIF":0.0,"publicationDate":"2020-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47921281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differentiation of a retroperitoneal mass with somatostatin receptor scintigraphy: a case report","authors":"Yaping Luo","doi":"10.3760/CMA.J.ISSN.2095-2848.2020.01.011","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.2095-2848.2020.01.011","url":null,"abstract":"","PeriodicalId":10099,"journal":{"name":"中华核医学与分子影像杂志","volume":"40 1","pages":"44-46"},"PeriodicalIF":0.0,"publicationDate":"2020-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45802962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"18F-FDG PET/CT imaging in uterine atypical polypoid adenomyoma: a case report","authors":"Shuai Liu, L. Xia, H. Ge, R. Li, YingJian Zhang, Huiyu Yuan, Linjun Lu, Shaoli Song","doi":"10.3760/CMA.J.ISSN.2095-2848.2020.01.008","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.2095-2848.2020.01.008","url":null,"abstract":"","PeriodicalId":10099,"journal":{"name":"中华核医学与分子影像杂志","volume":"40 1","pages":"37-38"},"PeriodicalIF":0.0,"publicationDate":"2020-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45346426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of whole-body bone scintigraphy and SPECT/CT imaging in osteoid osteoma","authors":"Huipan Liu, Lin Liu, Wei Zhang","doi":"10.3760/CMA.J.ISSN.2095-2848.2020.01.003","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.2095-2848.2020.01.003","url":null,"abstract":"Objective \u0000To analyze features of osteoid osteoma on whole-body bone scan (WBS) and SPECT/CT imaging. \u0000 \u0000 \u0000Methods \u0000From January 2010 to December 2018, 70 patients (50 males, 20 females, age: 4-66 years) with osteoid osteoma confirmed by pathology were enrolled from the Affiliated Hospital of Southwest Medical University. All patients underwent WBS and SPECT/CT imaging and imaging features were retrospectively analyzed. \u0000 \u0000 \u0000Results \u0000A total of 70 lesions were found by WBS combined with SPECT/CT imaging, and 26 lesions (37.1%, 26/70) were found in the femur and 25 lesions (35.7%, 25/70) in the tibia. The radioactive ratio of target lesion to non-target lesion (T/NT) was 3.7±1.2 in 56 patients who underwent three-phase bone imaging. WBS showed that 48 lesions (68.6%, 48/70) were round (or nearly round), 21 lesions (30%, 21/70) were spindle-shaped, and 1 lesion (1.4%, 1/70) was irregular-shaped, while SPECT/CT imaging showed that 69 lesions (98.6%, 69/70) were round (or round) and 1 lesion (1.4%, 1/70) was irregular-shaped. The \" double-density sign\" was found in 48 lesions (68.6%, 48/70) by WBS and in 59 lesions (84.3%, 59/70) by SPECT/CT imaging. SPECT/CT imaging detected nidus in 59 lesions (84.3%, 59/70) and calcification or ossification (\" target sign\" ) in 27 lesions (38.6%, 27/70). \u0000 \u0000 \u0000Conclusion \u0000The typical features of osteoid osteoma on WBS and SPECT/CT imaging include \" double density sign\" , nidus and \" target sign\" , which contribute to the diagnosis of osteoid osteoma. \u0000 \u0000 \u0000Key words: \u0000Osteoma, osteoid; Radionuclide imaging; Tomography, emission-computed, single-photon; Tomography, X-ray computed; Technetium Tc 99m medronate","PeriodicalId":10099,"journal":{"name":"中华核医学与分子影像杂志","volume":"40 1","pages":"11-15"},"PeriodicalIF":0.0,"publicationDate":"2020-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48098437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case report of thyroid cancer combined with Langerhans cell histiocytosis","authors":"Xiao-Ping Niu, Lihong Shi, Shasha Xu, Xinli Xie","doi":"10.3760/CMA.J.ISSN.2095-2848.2020.01.010","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.2095-2848.2020.01.010","url":null,"abstract":"","PeriodicalId":10099,"journal":{"name":"中华核医学与分子影像杂志","volume":"40 1","pages":"41-43"},"PeriodicalIF":0.0,"publicationDate":"2020-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49123243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Without physical corrections impacts the performance of myocardial blood flow quantitation with multi-pinhole CZT-SPECT","authors":"Rongzheng Ma, Meng Wang, Zongyao Zhang, Kai Han, Hailong Zhang, Lei Wang, B. Hsu, W. Fang","doi":"10.3760/CMA.J.ISSN.2095-2848.2019.12.004","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.2095-2848.2019.12.004","url":null,"abstract":"Objective \u0000To investigate the impact on myocardial blood flow (MBF) quantitation with multi-pinhole cadmium zinc telluride (CZT)-SPECT with or without partial physical corrections. \u0000 \u0000 \u0000Methods \u0000A total of 30 patients (18 males, 12 females; age: (63±9) years) with suspected or known coronary heart diseases who underwent dynamic SPECT from July 2018 to January 2019 in Fuwai Hospital were enrolled. Images were reconstructed using different corrections: no correction (NC), partial corrections ((noise reduction (NR), NR+ scatter correction (SC), NR+ SC+ resolution recovery (RR)), NR+ SC+ RR+ attenuation correction (AC; total corrections, TC). Kinetic modeling integrated one-tissue two-compartment model while using index of fitting quality (R2) and fraction blood volume (FBV) to assess the quality of modeling. Rest MBF (RMBF), stress MBF (SMBF) and myocardial flow reserve (MFR) quantified from no correction (NC) or partial corrections were compared with those of TC. Wilcoxon signed rank test and linear regression analysis were used to analyze the data. \u0000 \u0000 \u0000Results \u0000Compared to TC, NC showed the lowest R2 (rest: 0.69, stress: 0.78; z values: 4.78 and 4.78, both P<0.01) and highest FBV (rest: 0.37, stress: 0.40; z values: -3.40 and -3.30, both P<0.01). The improvement of R2 and FBV was consistent with increased corrective terms. Compared with TC, NC overestimated SMBF and MFR (z values: 1.27 and -3.50, both P<0.01), all partial corrections overestimated RMBF and SBMF (z values: from -4.55 to 1.27, all P<0.01). NR and NR+ SC underestimated MFR (both P<0.05). Linear regression analysis showed that the regressive coefficients of RMBF between NC, NR, NR+ SC, NR+ SC+ RR and TC were 0.908-1.210, and Bland-Altman plots of RMBF demonstrated positive or negative biases (-0.07, 0.21, 0.26, 0.15 ml·min-1·g-1). The regression coefficients of SMBF were 1.129-1.308, and Bland-Altman plots demonstrated positive biases (0.60, 0.25, 0.28, 0.24 ml·min-1·g-1). The regression coefficients of MFR were 0.907-1.318, and Bland-Altman plots demonstrated positive or negative biases (0.70, -0.11, -0.05, 0.01). \u0000 \u0000 \u0000Conclusion \u0000Full physical corrections can improve the index of fitting quality in the kinetic modeling and reduce left ventricle spillover, which help to warrant the accuracy of SPECT myocardial blood flow quantitation with multi-pinhole CZR-SPECT. \u0000 \u0000 \u0000Key words: \u0000Coronary artery disease; Myocardial perfusion imaging; Tomography, emission-computed, single-photon; Tellurium; Zinc; Cadmium; Attenuation correction","PeriodicalId":10099,"journal":{"name":"Chinese Journal of Nuclear Medicine and Molecular Imaging","volume":"39 1","pages":"720-725"},"PeriodicalIF":0.0,"publicationDate":"2019-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49034072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incremental value of coronary flow reserve assessed by CZT-SPECT in the diagnosis of coronary ar-tery disease","authors":"C. Weijia, Yao-wen Kang, Li Chenguang, Yu Haojun, Pan Lifang, G. Junbo, Shi Hong-cheng","doi":"10.3760/CMA.J.ISSN.2095-2848.2019.12.003","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.2095-2848.2019.12.003","url":null,"abstract":"Objective \u0000To investigate the incremental value of coronary flow reserve (CFR) assessed by cadmium zinc telluride(CZT)-SPECT as an adjunct to myocardial perfusion imaging (MPI) in the diagnosis of coronary artery disease (CAD). \u0000 \u0000 \u0000Methods \u0000Data of 132 patients (89 males, 43 females; 40-81 years) with or suspected with CAD who successfully underwent rest and stress MPI and CFR from November 2017 to October 2018 in Zhongshan Hospital Affiliated to Fudan University were retrospectively analyzed. Based on coronary angiography (CAG) as the \" gold standard\" , the value of MPI and MPI+ CFR in the diagnosis of CAD was evaluated and compared. χ2 test or Fisher exact probability test was used for data analysis. \u0000 \u0000 \u0000Results \u0000Of 132 patients, 61 (46.2%) were CAD with stenosis of at least 75% in one vessel (47.5%, 29/61), two vessels (34.4%, 21/61), or three vessels (18.0%, 11/61). A total of 104 (26.3%) vessels with stenosis of at least 75%, 25 (6.3%) vessels with stenosis of 65%-74%, and 30 (7.6%) vessels with stenosis of 50%-64% were found in 396 vessels. For detecting coronary stenosis of at least 75%, the sensitivity and accuracy of MPI on per-patient analysis were 86.89%(53/61) and 68.94%(91/132), which increased to 96.72%(59/61; χ2=3.921, P<0.05) and 87.88%(116/132; χ2=13.984, P<0.01) by MPI+ CFR. On per-vessel analysis, the sensitivity and accuracy of MPI were 72.12%(75/104) and 77.53%(307/396) and increased to 96.15%(100/104; χ2=22.511, P<0.01) and 85.10%(337/396; χ2=7.479, P<0.05) by MPI+ CFR. The sensitivity of MPI for predicting one, two, and three vessels disease were 72.41%(21/29), 42.86%(9/21), and 5/11 and were improved to 93.10%(27/29; χ2=4.350, P=0.037), 90.48%(19/21; χ2=10.714, P=0.001), and 11/11 (P=0.012) by MPI+ CFR. For coronary with stenosis of 65%-74%, the sensitivity of MPI was 24.00%(6/25) and was improved to 64.00%(16/25; χ2=8.117, P=0.004) by MPI+ CFR. For coronary with stenosis of 50%-64%, the sensitivity of MPI was 40.00%(12/30) and was improved to 76.67%(23/30; χ2=8.297, P=0.004) by MPI+ CFR. \u0000 \u0000 \u0000Conclusion \u0000As an adjunct to MPI, CFR can significantly improve the sensitivity and accuracy in the diagnosis of CAD, particularly for patients with mild stenosis and multivessel CAD. \u0000 \u0000 \u0000Key words: \u0000Coronary artery disease; Fractional flow reserve, myocardial; Myocardial perfusion imaging; Tomography, emission-computed, single-photon; Tellurium; Zinc; Cadmium","PeriodicalId":10099,"journal":{"name":"Chinese Journal of Nuclear Medicine and Molecular Imaging","volume":"39 1","pages":"714-719"},"PeriodicalIF":0.0,"publicationDate":"2019-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43980266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}