Medical Reports最新文献_第9页

A challenge to clinical management: A case of expanded dengue syndrome co-infection with dengue 1 and dengue 3 serotypes in Nepal 临床管理的挑战：尼泊尔一例登革1型和登革3型血清型合并感染的登革热综合征扩大病例

Medical Reports Pub Date : 2024-10-24 DOI: 10.1016/j.hmedic.2024.100123

Sabin Shrestha , Milan Bajracharya , Sandesh Rimal , Rajshree Bhujel , Bimal Chalise , Yuba Nidhi Basaula , Prasanna Amatya , Shrijana Pandey , Pratik Joshi , Nabaraj Adhikari , Mya Myat Ngwe Tun , Kouichi Morita , Shyam Prakash Dumre , Basu Dev Pandey

{"title":"A challenge to clinical management: A case of expanded dengue syndrome co-infection with dengue 1 and dengue 3 serotypes in Nepal","authors":"Sabin Shrestha , Milan Bajracharya , Sandesh Rimal , Rajshree Bhujel , Bimal Chalise , Yuba Nidhi Basaula , Prasanna Amatya , Shrijana Pandey , Pratik Joshi , Nabaraj Adhikari , Mya Myat Ngwe Tun , Kouichi Morita , Shyam Prakash Dumre , Basu Dev Pandey","doi":"10.1016/j.hmedic.2024.100123","DOIUrl":"10.1016/j.hmedic.2024.100123","url":null,"abstract":"<div><div>Rapid progression to fatal expanded dengue syndrome is unusual, presenting a challenge for clinical management. We present a case of a 32-year-old female with atypical dengue manifestations who underwent extensive evaluation at a Kathmandu infectious disease hospital, including vital signs assessment, clinical scoring, and routine and advanced laboratory analyses. Severe abdominal pain, disorientation, and abnormal hemodynamics with multi-organ involvement were noted with a secondary dengue virus (DENV) infection. Co-infection of DENV-1 and DENV-3, exhibiting high viral loads, was observed, marking the first fatal case of its kind in Nepal. Despite intensive care management, the patient’s condition rapidly deteriorated, leading to fatal expanded dengue syndrome within four days of a hospital visit. This poses a serious challenge to clinicians. Heightened vigilance from the onset of DENV infection is imperative, regardless of serotypes or viral load levels. Predictive markers for early detection and management strategies are urgently needed to achieve the WHO's goal of zero dengue-related deaths by 2030.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"8 ","pages":"Article 100123"},"PeriodicalIF":0.0,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142538297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Invasive ductal carcinoma in a male patient: A case report 一名男性患者的浸润性导管癌：病例报告

Medical Reports Pub Date : 2024-10-23 DOI: 10.1016/j.hmedic.2024.100122

Muhammad Usama Bin Shabbir , Muhammad Bilal , Sikandar Ajmal Abbasi , Afaq Ahmad , Ahmad Abubakr

{"title":"Invasive ductal carcinoma in a male patient: A case report","authors":"Muhammad Usama Bin Shabbir , Muhammad Bilal , Sikandar Ajmal Abbasi , Afaq Ahmad , Ahmad Abubakr","doi":"10.1016/j.hmedic.2024.100122","DOIUrl":"10.1016/j.hmedic.2024.100122","url":null,"abstract":"<div><h3>Introduction and importance</h3><div><em>Male breast cancer</em> is a rare condition, representing less than one per cent of all breast cancer cases. It is characterized by late presentation and a higher incidence of metastatic disease due to diagnostic delays. In Pakistan, male breast cancer tends to appear at a younger age than in Western countries. Risk factors include advancing age, hormonal imbalances, and family history. Despite the proven effectiveness of neoadjuvant chemotherapy, its adoption in clinical practice is limited.</div></div><div><h3>Case presentation</h3><div>This case involves a fifty-six-year-old Pakistani man presenting with a lump in his right breast. The physical examination showed a lump with axillary lymphadenopathy and skin changes. Laboratory tests were within normal ranges, and imaging revealed a highly suspicious lesion in the right breast. After a modified radical mastectomy, the biopsy confirmed grade two invasive ductal carcinoma with lymph node metastasis.</div></div><div><h3>Clinical discussion</h3><div>The case highlights the need to consider male breast cancer in diagnoses. Male breast cancer differs from female breast cancer in its pathology, with a higher expression of the estrogen receptor-beta. The patient, who tested negative for BRCA1 and BRCA2 mutations, received chemotherapy followed by surgery, underscoring the importance of personalized treatment.</div></div><div><h3>Conclusion</h3><div>Male breast cancer is among the rarest cancers globally, requiring more research and awareness to improve management and outcomes. Dispelling the myth that breast cancer is a female-only disease is vital for early detection and treatment, which could enhance survival rates.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"8 ","pages":"Article 100122"},"PeriodicalIF":0.0,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142538408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intestinal type of sinonasal adenocarcinoma with condylar metastases: A case report 伴有髁状突转移的肠型鼻窦腺癌：病例报告

Medical Reports Pub Date : 2024-10-23 DOI: 10.1016/j.hmedic.2024.100124

Karpagaselvi Sanjai , Sumana Bukanakere Sangappa , Divya Shivalingaiah , Anjum Baker , Roopa Rao

{"title":"Intestinal type of sinonasal adenocarcinoma with condylar metastases: A case report","authors":"Karpagaselvi Sanjai , Sumana Bukanakere Sangappa , Divya Shivalingaiah , Anjum Baker , Roopa Rao","doi":"10.1016/j.hmedic.2024.100124","DOIUrl":"10.1016/j.hmedic.2024.100124","url":null,"abstract":"<div><div>Intestinal type sinonasal adenocarcinoma (ITAC) is a locally aggressive, rare malignancy occurring mostly in elderly males. It is the second most common sinonasal adenocarcinoma, with characteristic microscopic features in their marked resemblance to intestinal mucosa. It also has a well-documented association with prolonged occupational exposure to wood dust. Here we report a case of papillary variant of ITAC originating in the ethmoid sinus with metastasis to the mandibular condyle. A 53 year old male, bookseller by profession reported to outpatient department with difficulty in mouth opening since five months. On examination, he had swelling with pain and tenderness on the right side of face and the right temporomandibular joint (TMJ) area. The radiographs revealed a destructive mass in the right ethmoid sinus, encroaching into the maxillary antrum, orbit and nasal cavity along with beak like erosion of anteromedial aspect of the right condyle. The hematoxylin and eosin stained sections showed presence of glandular structures, recapitulating intestinal mucosal morphology and papillary arrangement of stratified tall columnar cells with dysplastic features. Immunohistochemical stain with CK20, CD-X2, CK7 and villin was positive. The patient was referred to oncology department for further treatment. This case reiterates the importance of proper clinical evaluation of the patient to consider profession related lesions. Metastases from Sinonasal adenocarcinomas can be considered for differential diagnosis for inability to open mouth.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"8 ","pages":"Article 100124"},"PeriodicalIF":0.0,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142538298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evans syndrome: An uncommon hematological conundrum in a young adult: A case report 埃文斯综合征：一名年轻成人的罕见血液学难题：病例报告

Medical Reports Pub Date : 2024-10-17 DOI: 10.1016/j.hmedic.2024.100121

Faryal Afridi , Tooba Fida , Muhammad Usama Bin Shabbir , Hasban Ahmad Halim , Ishwa Ghouri , Muhammad Fawad Ashraf

引用次数: 0

Colon cancer disguised as intussusception in a young adult: A case report 伪装成肠套叠的年轻成人结肠癌：病例报告

Medical Reports Pub Date : 2024-10-15 DOI: 10.1016/j.hmedic.2024.100119

Anthony El Dada , Yara El Ratel , Mandy El Khoury , Karam Karam , Mahmoud Othman

{"title":"Colon cancer disguised as intussusception in a young adult: A case report","authors":"Anthony El Dada , Yara El Ratel , Mandy El Khoury , Karam Karam , Mahmoud Othman","doi":"10.1016/j.hmedic.2024.100119","DOIUrl":"10.1016/j.hmedic.2024.100119","url":null,"abstract":"<div><h3>Background</h3><div>Intussusception is exceedingly rare in adults and is often unthought off as a differential diagnosis for abdominal pain. Here, we describe the case of intussusception in a young female unveiling colon adenocarcinoma.</div></div><div><h3>Case presentation</h3><div>A 36-year-old female, previously healthy, presented for abdominal pain and bloody diarrhea of 2 days duration. The patient was initially treated for Amebiasis. She sought medical care the next day with tenesmus and lancinating abdominal pain, leading to hospitalization for further work-up. Computed tomography (CT) scan revealed an obstruction of the large bowel with dilation of the transverse colon reaching 6 cm. The obstruction was caused by a collapsed, intussuscepted descending colon, with mesenteric fat and vessels telescoped into its lumen along with a 3.7 cm wall thickening. She was scheduled for surgical repair.</div></div><div><h3>Conclusion</h3><div>A well-timed CT scan is necessary for favorable patient outcomes. Due to their rare occurrence in young adults, intussusception and colon cancer, could potentially go undiagnosed.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"8 ","pages":"Article 100119"},"PeriodicalIF":0.0,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142442288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diffuse alveolar haemorrhage as an initial presenting manifestation of juvenile systemic lupus erythematosus 弥漫性肺泡出血是幼年系统性红斑狼疮的初始表现

Medical Reports Pub Date : 2024-10-15 DOI: 10.1016/j.hmedic.2024.100120

Ishwarya Ramadoss , Arul Rajamurugan Ponniah Subramanian, Ramesh R

引用次数: 0

Seeding of glioblastoma multiforme in the fourth ventricle leading to bilateral internuclear ophthalmoplegia: A case report 第四脑室多形性胶质母细胞瘤播种导致双侧核内性眼瘫：病例报告

Medical Reports Pub Date : 2024-10-11 DOI: 10.1016/j.hmedic.2024.100118

Mahzareen, Saba Zaidi, Muhammad Mubashir

{"title":"Seeding of glioblastoma multiforme in the fourth ventricle leading to bilateral internuclear ophthalmoplegia: A case report","authors":"Mahzareen, Saba Zaidi, Muhammad Mubashir","doi":"10.1016/j.hmedic.2024.100118","DOIUrl":"10.1016/j.hmedic.2024.100118","url":null,"abstract":"<div><div>Internuclear ophthalmoplegia (INO) is an infrequent disorder impacting conjugate lateral gaze. It is typically observed in neurological conditions like multiple sclerosis and stroke, but it is rarely linked to brain tumors. This report describes a case where INO developed in a patient with a high grade astrocytoma. A 42-year-old man presented with a one-week history of worsening horizontal double vision. Examination revealed impaired adduction and horizontal nystagmus without additional focal neurological deficits or papilledema. MRI imaging of the brain with contrast revealed a large, heterogeneous mass in the left frontal lobe along with ring-enhancing lesions in the fourth ventricle, suggesting tumor progression. The patient had previously undergone a gross total resection of a Grade-4 astrocytoma, followed by radiation therapy and Temozolomide treatment. In response to the new onset of INO, his treatment regimen was adjusted to continue Temozolomide and include steroids. This case underscores the importance of recognizing new ophthalmologic findings as a potential indicator of tumor progression in high-grade astrocytomas, highlighting the need for careful monitoring and treatment modification.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"8 ","pages":"Article 100118"},"PeriodicalIF":0.0,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142441658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent advancement of deep learning techniques for pneumonia prediction from chest X-ray image 从胸部 X 光图像预测肺炎的深度学习技术最新进展

Medical Reports Pub Date : 2024-10-01 DOI: 10.1016/j.hmedic.2024.100106

Md. Rabiul Hasan, Shah Muhammad Azmat Ullah, Sheikh Md. Rabiul Islam

{"title":"Recent advancement of deep learning techniques for pneumonia prediction from chest X-ray image","authors":"Md. Rabiul Hasan, Shah Muhammad Azmat Ullah, Sheikh Md. Rabiul Islam","doi":"10.1016/j.hmedic.2024.100106","DOIUrl":"10.1016/j.hmedic.2024.100106","url":null,"abstract":"<div><div>Pneumonia is a life-threatening, acute lung infection found all over the world that mostly affects the lungs. Computer vision-related automatic detection algorithms are currently highly used in research areas like medical imaging. Deep learning algorithms have enabled some impressive improvements in medical diagnosis in recent years. This study provides a summary of a recently developed DL-based pneumonia diagnosis system as well as important details about the data sets used for the training and testing of those networks. Additionally, it emphasizes the ensemble learning and deep transfer learning methodologies as well as the many performance measurements created by researchers in this field. The most recent research publications are reviewed here and collected from different sources like Scopus, Google Scholar, PubMed, ResearchGate, and IEEE Xplore databases using the terms “Pneumonia”, “Deep-Learning”, “X-Ray” and “CNN”. The most current works are organized according to a taxonomy for easier understanding. Lastly, we addressed the limitations in deploying deep learning methods to the detection of pneumonia and potential future developments in this field of study. This study aims to assist experts in select the most suitable and effective methods for pneumonia detection.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"7 ","pages":"Article 100106"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142421102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hyperkalemia-induced periodic paralysis, a rare presentation of ascending flaccid paralysis: A case report and review of literature 高钾血症诱发的周期性麻痹，一种罕见的上升性弛缓性麻痹表现：病例报告和文献综述

Medical Reports Pub Date : 2024-09-23 DOI: 10.1016/j.hmedic.2024.100116

Muhammad Ahmad Khan , Waqar Ali , Umar Maqbool , Wajeeha Aslam , Muhammad Danial Malik , Muhammad Waleed Khan

{"title":"Hyperkalemia-induced periodic paralysis, a rare presentation of ascending flaccid paralysis: A case report and review of literature","authors":"Muhammad Ahmad Khan , Waqar Ali , Umar Maqbool , Wajeeha Aslam , Muhammad Danial Malik , Muhammad Waleed Khan","doi":"10.1016/j.hmedic.2024.100116","DOIUrl":"10.1016/j.hmedic.2024.100116","url":null,"abstract":"<div><h3>Background</h3><div>Severe hyperkalemia is a life-threatening complication of kidney disease in acute or chronic states. Hyperkalemia-induced muscle paralysis is a manifestation of severe hyperkalemia, usually seen when serum potassium levels rise above 6.5 mEq/L, along with cardiac arrhythmia requiring emergency management.</div></div><div><h3>Case report</h3><div>A 60-year-old Asian male presented in the medical emergency with paraparesis for 6 hours. On examination, he had flaccid paraparesis without any sensory loss. His ECG showed changes of hyperkalemia, and his potassium levels came out to be 8.1 mEq/L. The weakness resolved following the correction of hyperkalemia with a regimen containing an insulin-dextrose infusion and salbutamol nebulizations.</div></div><div><h3>Conclusion</h3><div>Although rare, severe hyperkalemia is a cause of periodic paralysis, especially in patients with risk factors such as end-stage renal disease (ESRD). Prompt treatment of hyperkalemia can resolve paralysis even before hemodialysis. The report aims to educate physicians about an essential differential of flaccid paralysis.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"7 ","pages":"Article 100116"},"PeriodicalIF":0.0,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142318827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Esophagogastric fistula in an adult following laparoscopic Nissen fundoplication: A case report of successful resolution of fistulization through conservative medical therapy 腹腔镜尼森胃底折叠术后成人食管胃瘘：通过保守疗法成功解决瘘管问题的病例报告

Medical Reports Pub Date : 2024-09-19 DOI: 10.1016/j.hmedic.2024.100114

Karam Karam , Emanuel Youssef Dib , Houssein Chebbo , Sarah Saleh , Karim Zodeh , Lamia Azizi , Majd Rustom

引用次数: 0