Medical Reports最新文献_第9页

The “breathless heart” of a 38-year-old healthcare worker: A case report 38岁医护人员“喘不过气来的心脏”：病例报告

Medical Reports Pub Date : 2025-03-29 DOI: 10.1016/j.hmedic.2025.100188

Emmanouil Mantzouranis , Panayotis K. Vlachakis , Theofani Rimpa , Ioannis Leontsinis , Eleftheria Kakargia , Stamatis Katsenos , Ioannis Mamarelis , Kyriakos Dimitriadis , Konstantinos Tsioufis

{"title":"The “breathless heart” of a 38-year-old healthcare worker: A case report","authors":"Emmanouil Mantzouranis , Panayotis K. Vlachakis , Theofani Rimpa , Ioannis Leontsinis , Eleftheria Kakargia , Stamatis Katsenos , Ioannis Mamarelis , Kyriakos Dimitriadis , Konstantinos Tsioufis","doi":"10.1016/j.hmedic.2025.100188","DOIUrl":"10.1016/j.hmedic.2025.100188","url":null,"abstract":"<div><h3>Background</h3><div>COVID-19 has been associated with a wide spectrum of cardiovascular conditions. On the other hand, patients hospitalized with severe acute respiratory distress syndrome (ARDS) may often require long-term intubation. Laryngotracheal stenosis (LTS) is a well described complication of the latter, potentially leading to acute airway obstruction.</div></div><div><h3>Case summary</h3><div>We present the case of a 38-year-old healthcare worker with acute respiratory failure due to LTS as a complication of prior intubation for COVID-19. Emergent therapeutic bronchoscopy successfully treated airway obstruction. ECG alterations, accompanied by elevated troponin and wall motion abnormalities raised the suspicion for acute coronary syndrome, without signs of active infection. Coronary computed tomography angiography led to the diagnosis of myocardial infarction with non-obstructive coronary arteries (MINOCA). Cardiac magnetic resonance (CMR) revealed patchy non-ischemic lesions. 3-month ECG and echocardiogram were normal suggesting Takotsubo syndrome (TTS) the most likely diagnosis. Patient was finally treated by implantation of an endotracheal silicone hourglass stent.</div></div><div><h3>Discussion</h3><div>Our case highlights the importance of multidisciplinary medical management. A definite diagnosis of TTS requires the performance of a CMR and the reversal of systolic dysfunction. LTS is a well described complication of long-term intubation and a high index of suspicion is warranted. Treatment is individualized including interventional treatments and surgical techniques.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"11 ","pages":"Article 100188"},"PeriodicalIF":0.0,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143738316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Speech arrest as sole presenting symptom of midline seizures – A case report 言语停止是中线癫痫发作的唯一表现症状- 1例报告

Medical Reports Pub Date : 2025-03-29 DOI: 10.1016/j.hmedic.2025.100190

Michael Fana, Ahmad Yusuf-Solaiman, Ahmad Riad Ramadan

引用次数: 0

Anti-HMGCR myopathy secondary to statins diagnosed in the emergency department 急诊诊断继发于他汀类药物的抗hmgcr肌病

Medical Reports Pub Date : 2025-03-27 DOI: 10.1016/j.hmedic.2025.100194

Claire M. Halberg , Matthew P. Lazio

{"title":"Anti-HMGCR myopathy secondary to statins diagnosed in the emergency department","authors":"Claire M. Halberg , Matthew P. Lazio","doi":"10.1016/j.hmedic.2025.100194","DOIUrl":"10.1016/j.hmedic.2025.100194","url":null,"abstract":"<div><div>Statins (hydroxymethylglutaryl‐coenzyme A (HMG-CoA) reductase inhibitors) are a class of medication often used to control cholesterol levels. Anti-3-hydroxymethylglutaryl-coenzyme A reductase (anti-HMGCR) myopathy is a rare form of autoimmune myositis which presents as a result of statin therapy. In this report, we present the case of a 63-year-old male presenting to the emergency department (ED) with inability to ambulate, proximal muscle weakness, elevated creatine kinase (CK) and prior quadriceps muscle biopsy demonstrating highly active and chronic necrotizing myopathy. A presumptive diagnosis of anti-HMGCR myopathy was made in the ED, HMGCR antibody IgG was ordered, and was markedly elevated when it resulted a few days later. He was hospitalized and started on systemic corticosteroids and intravenous immunoglobulin (IVIG). He was ultimately discharged with home health, physical therapy, monthly IVIG infusions, prednisone taper starting at 80 mg daily, biweekly creatinine kinase measurements, and rheumatology and neurology follow-up. These measures successfully reduced his symptoms, and his mobility had increased at the time of follow-up to the point that he could again ambulate. Anti-HMGCR myopathy should remain on the emergency physician’s differential for a patient currently on or previously exposed to statins presenting with proximal muscle weakness.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"11 ","pages":"Article 100194"},"PeriodicalIF":0.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143816713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The rash that unraveled: A case report of DRESS syndrome in a 45-year-old woman 皮疹解除：一个45岁妇女的DRESS综合征病例报告

Medical Reports Pub Date : 2025-03-27 DOI: 10.1016/j.hmedic.2025.100192

Aqsa Saleem , Haris Waheed , Sampana Fatima

引用次数: 0

Mad honey intoxication: A case report from eastern Nepal 疯狂蜂蜜中毒：尼泊尔东部1例报告

Medical Reports Pub Date : 2025-03-25 DOI: 10.1016/j.hmedic.2025.100189

Akash Roy , Sumit Kumar Singh , Suman Rijal , Abinash Kumar Sah , Anjan Nepali

{"title":"Mad honey intoxication: A case report from eastern Nepal","authors":"Akash Roy , Sumit Kumar Singh , Suman Rijal , Abinash Kumar Sah , Anjan Nepali","doi":"10.1016/j.hmedic.2025.100189","DOIUrl":"10.1016/j.hmedic.2025.100189","url":null,"abstract":"<div><div>Mad honey poisoning, caused by ingestion of honey contaminated with grayanotoxins from specific rhododendron species, poses health risks in regions like Nepal, Turkey, Canada, and Japan. Grayanotoxins bind to sodium channels, leading to prolonged depolarisation and causing bradycardia and hypotension. Historically used in traditional medicine, mad honey’s recent recreational consumption has increased, leading to cases of intoxication from excessive use. We report a case of mad honey poisoning in a 53-year-old woman who consumed approximately 30 mL of honey bought from eastern Nepal, presenting with drowsiness, bradycardia, and hypotension. Despite initial stabilization with atropine, hydrocortisone, and fluid resuscitation, her condition required prolonged monitoring for 72 h. This case highlights the need to consider mad honey poisoning in patients presenting with altered sensorium or unexplained hypotension, even outside endemic regions. Efforts to raise public awareness, regulate honey sales, and improve diagnostic capabilities are essential to prevent and manage future cases. Further studies on toxin variability and rhododendron species in Nepal are also needed.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"11 ","pages":"Article 100189"},"PeriodicalIF":0.0,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143738497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Co-transmission of Stenotrophomonas maltophilia and leishmaniasis by Phlebotomus argentipes (sandfly)? A case report 嗜麦芽窄养单胞菌和利什曼病由阿根廷白蛉（白蛉）共同传播？病例报告

Medical Reports Pub Date : 2025-03-25 DOI: 10.1016/j.hmedic.2025.100193

Dimuthu Indunil Karunasinghe , Thilina Rathnasekara , Wasantha Karunarathne , Chamara Sarathchandra , Sisira Siribaddana

引用次数: 0

Sympathetic ophthalmia with bilateral vision loss: A case report 交感性眼炎伴双侧视力丧失1例

Medical Reports Pub Date : 2025-03-14 DOI: 10.1016/j.hmedic.2025.100185

Abhineet Kumar , Sneha Kumar , Taranjit Gill

{"title":"Sympathetic ophthalmia with bilateral vision loss: A case report","authors":"Abhineet Kumar , Sneha Kumar , Taranjit Gill","doi":"10.1016/j.hmedic.2025.100185","DOIUrl":"10.1016/j.hmedic.2025.100185","url":null,"abstract":"<div><h3>Background</h3><div>Sympathetic Ophthalmia [SO] is a rare condition with potentially devastating outcomes, characterized by bilateral uveitis following ocular trauma or surgery.</div></div><div><h3>Findings</h3><div>We present a case of a male in his 60s with no notable medical history who experienced bilateral vision loss following a traumatic injury. In 2006, the patient sustained trauma to his right eye after being elbowed by a patient, leading to a detached retina. Despite treatment with corticosteroids, immunomodulators, and multiple surgical interventions—including three buckle surgeries and two nitrous oxide gas treatments—the retina remained detached, resulting in complete vision loss and eventual enucleation of the right eye in 2012. Approximately one year later, the patient developed floaters and flashing lights in the left eye, diagnosed as a partial retinal tear, which was treated with laser therapy. Over the next decade, the left eye underwent six additional surgeries, immunotherapy, and participation in a clinical trial involving monthly intraocular injections to reduce swelling. Despite these efforts, intraocular pressure fluctuated significantly, reaching as high as 58 mmHg, and the patient ultimately lost all vision in the left eye by November 2023, requiring enucleation. Histopathology confirmed the diagnosis, and all tests for autoimmune conditions were negative. This case highlights the challenges of managing recurrent retinal detachment and refractory intraocular inflammation despite aggressive medical and surgical interventions.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"11 ","pages":"Article 100185"},"PeriodicalIF":0.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143687579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Disseminated histoplasmosis and resistant tuberculosis in a patient with AIDS: A case report 一名艾滋病患者的播散性组织胞浆菌病和耐药性结核病：病例报告

Medical Reports Pub Date : 2025-03-12 DOI: 10.1016/j.hmedic.2025.100186

Luis E.B. Galan , Dandara M. Honorato , Stephanye B. Andrade , Manoel M.S. Neto , Artur D.P. Paiva , Eloise T.M. Filardi , Marcela Romanazzi , Domingos S.M. Dantas , Roberto C. Carbonell , Felipe A. Cerni , Manuela B. Pucca

{"title":"Disseminated histoplasmosis and resistant tuberculosis in a patient with AIDS: A case report","authors":"Luis E.B. Galan , Dandara M. Honorato , Stephanye B. Andrade , Manoel M.S. Neto , Artur D.P. Paiva , Eloise T.M. Filardi , Marcela Romanazzi , Domingos S.M. Dantas , Roberto C. Carbonell , Felipe A. Cerni , Manuela B. Pucca","doi":"10.1016/j.hmedic.2025.100186","DOIUrl":"10.1016/j.hmedic.2025.100186","url":null,"abstract":"<div><div>Histoplasmosis is a systemic mycosis with a wide global distribution, being more prevalent and endemic in the American Continent. Its progressive disseminated form primarily affects immunosuppressed individuals and plays a significant role as an AIDS-defining illness. The challenging aspect of differential diagnosis with tuberculosis lies in the clinical, radiological, and laboratory similarities between these two conditions, making the spectrum of co-infection even more complex. In this clinical study, we present the case of a 22-year-old Venezuelan patient with no prior comorbidities who was admitted with symptoms of diarrhea, fever, weight loss, and persistent cough over a 30-day period. Initially, he was diagnosed with acquired immunodeficiency syndrome (AIDS) and subsequently with pulmonary tuberculosis. However, due to the persistence of symptoms, the delayed diagnosis of disseminated histoplasmosis (DH) was also established through blood culture. Additionally, the patient exhibited resistance to rifampicin, a condition not previously documented in the literature. After treatment with amphotericin B, adjustment of the tuberculosis therapy, and initiation of antiretroviral therapy, the patient experienced a significant clinical improvement and currently remains asymptomatic. This case underscores the importance of raising clinical suspicion for disseminated histoplasmosis (DH) in HIV-infected patients and implementing enhanced diagnostic strategies, especially in regions with limited access to healthcare services and complementary examinations.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"11 ","pages":"Article 100186"},"PeriodicalIF":0.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143611151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute severe methemoglobinemia caused by accidental liquid shoe shiner ingestion: A case report and review of literature 意外摄入擦鞋液导致急性重度高铁血红蛋白血症：病例报告和文献综述

Medical Reports Pub Date : 2025-03-11 DOI: 10.1016/j.hmedic.2025.100187

Muhammad Fawad Ashraf , Hafsa Fayyaz , Safi Ur Rehman Daim , Bushra Khalid , Maham Ashraf , Muhammad Aizaz Ashraf

{"title":"Acute severe methemoglobinemia caused by accidental liquid shoe shiner ingestion: A case report and review of literature","authors":"Muhammad Fawad Ashraf , Hafsa Fayyaz , Safi Ur Rehman Daim , Bushra Khalid , Maham Ashraf , Muhammad Aizaz Ashraf","doi":"10.1016/j.hmedic.2025.100187","DOIUrl":"10.1016/j.hmedic.2025.100187","url":null,"abstract":"<div><div>Nitrobenzene, an aromatic compound is responsible for a lethal condition called methemoglobinemia. Nitrobenzene toxicity results from inhalation, ingestion, and skin contamination. It oxidizes Fe in the Hb and converts it into methemoglobin. The normal level of MetHb in the blood is 1 % and is maintained by RBCs. Greater production of MetHb than what can be maintained by RBCs results in Methemoglobinemia rendering Hb unable to deliver oxygen to tissues. Our report portrays the case of a 25-year-old male who ingested an unknown substance and presented with cyanosis and vomiting, having a bitter almond odor. Blood drawn for labs revealed chocolate color, a classic representation of methemoglobinemia. Treatment includes oxygen therapy, gastric lavage, IV methylene blue and if it's not available, an exchange transfusion can be done. Early identification of the condition is crucial for reducing morbidity and mortality. Businesses dealing with such toxic chemicals should be asked to maintain regular exposure checkups and plans available for ready access to medical management in case of emergency.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"11 ","pages":"Article 100187"},"PeriodicalIF":0.0,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143611150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cutibacterium acnes Brodie's abscess of the proximal tibia: A case report 胫骨近端痤疮表皮杆菌Brodie脓肿1例

Medical Reports Pub Date : 2025-03-10 DOI: 10.1016/j.hmedic.2025.100184

Zeina Morcos , Chloe Lahoud , Salman Khan , Gabrielle Dabrowski , Allison Glaser

{"title":"Cutibacterium acnes Brodie's abscess of the proximal tibia: A case report","authors":"Zeina Morcos , Chloe Lahoud , Salman Khan , Gabrielle Dabrowski , Allison Glaser","doi":"10.1016/j.hmedic.2025.100184","DOIUrl":"10.1016/j.hmedic.2025.100184","url":null,"abstract":"<div><h3>Introduction</h3><div>Brodie’s abscess, a subacute osteomyelitis, is characterized by a well-demarcated collection of purulence within the bone. It presents with nonspecific signs and symptoms. Diagnosing Brodie's abscess typically involves MRI, which is superior to conventional X-rays. It can be mistaken for osteoid osteoma, Langerhans cell histiocytosis, chondrosarcoma, eosinophilic granuloma, or tuberculosis. Staphylococcus aureus is the most common organism involved.</div></div><div><h3>Case Presentation</h3><div>We present a unique case of Brodie’s abscess within the proximal tibia secondary to Cutibacterium acnes, an unusual pathogen in Brodie’s Abscess, in a setting of previous right tibial shaft fracture with external fixation complicated by pin-site tract infection after many years.</div></div><div><h3>Discussion</h3><div>Traditionally viewed as a nonpathogenic contaminant due to its association with normal skin flora, C. acnes is often underdiagnosed and underreported in other infections due to inadequate culture media and subtle clinical symptoms. Treatment of Brodie’s abscess generally involves surgical debridement followed by antibiotics, though the optimal antibiotic regimen is unclear.</div></div><div><h3>Conclusion</h3><div>Further research is needed regarding atypical presentations of C. acnes such as our case.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"11 ","pages":"Article 100184"},"PeriodicalIF":0.0,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143593190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0