Chinese Chemical Letters最新文献_第2页

Crystal hydrogels: Strategies, properties, and applications 晶体水凝胶：策略、性质和应用

IF 8.9 1区化学

Chinese Chemical Letters Pub Date : 2026-05-01 Epub Date: 2025-08-11 DOI: 10.1016/j.cclet.2025.111707

Qianwei Liu , Xinhong Xiong , Numan Ahmed , Peisong Tang , Jiaxi Cui

引用次数: 0

[7]Cyclophenoxathiin: A heptagonal frustum-shaped nanobelt container for fullerenes [7]环苯氧嘧啶：富勒烯的七方锥状纳米带容器

IF 8.9 1区化学

Chinese Chemical Letters Pub Date : 2026-05-01 Epub Date: 2025-06-24 DOI: 10.1016/j.cclet.2025.111499

Zhenglin Du , Weijie Zhang , Yisong Tang , Xia Li , Jialin Xie , Kelong Zhu

{"title":"[7]Cyclophenoxathiin: A heptagonal frustum-shaped nanobelt container for fullerenes","authors":"Zhenglin Du , Weijie Zhang , Yisong Tang , Xia Li , Jialin Xie , Kelong Zhu","doi":"10.1016/j.cclet.2025.111499","DOIUrl":"10.1016/j.cclet.2025.111499","url":null,"abstract":"<div><div>Nanobelts have attracted significant attention in both synthetic and supramolecular chemistry due to their distinctive structures and promising applications. However, their synthesis remains challenging due to the high strain inherent in their ribbon-like configurations. A promising approach to mitigate this strain involves incorporating heteroatoms, such as sulfur and oxygen, which not only alleviate strain but also introduce new functionalities. In this study, we report the synthesis of a novel <em>C</em><sub>2</sub>-symmetric nanobelt, [7]cyclophenoxathiin (<strong>[7]CP</strong>), through a multi-step process. The structure of <strong>[7]CP</strong> was confirmed using NMR, mass spectrometry, and single-crystal X-ray diffraction, revealing a heptagonal frustum-shaped geometry. Host-guest interactions between <strong>[7]CP</strong> and selected fullerenes were investigated using UV–vis absorption, <sup>1</sup>H NMR, and X-ray crystallography. Our findings demonstrate that <strong>[7]CP</strong> forms 1:1 complexes with fullerenes, exhibiting moderate binding through <em>π</em>−<em>π</em> interactions, with binding constants of 1638, 2534, and 3682 L/mol for C<sub>60</sub>, C<sub>70</sub>, and PC<sub>61</sub>BM, respectively. The reduced cavity size of <strong>[7]CP</strong> prevents the formation of dimeric complexes observed with [7]cyclophenoxathiin, while still allowing it to function effectively as a molecular container.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"37 5","pages":"Article 111499"},"PeriodicalIF":8.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146186649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Facile and regioselective B–H bond functionalization of carboranes via cage···I(III) interaction 通过笼···I（III）相互作用实现碳硼烷B-H键的简单和区域选择性功能化

IF 8.9 1区化学

Chinese Chemical Letters Pub Date : 2026-05-01 Epub Date: 2025-07-21 DOI: 10.1016/j.cclet.2025.111617

Ping Zhang , Hongyuan Ren , Zhaofeng Sun , Hou-Ji Cao , Deshuang Tu , Chang-Sheng Lu , Jordi Poater , Miquel Solà , Hong Yan

{"title":"Facile and regioselective B–H bond functionalization of carboranes via cage···I(III) interaction","authors":"Ping Zhang , Hongyuan Ren , Zhaofeng Sun , Hou-Ji Cao , Deshuang Tu , Chang-Sheng Lu , Jordi Poater , Miquel Solà , Hong Yan","doi":"10.1016/j.cclet.2025.111617","DOIUrl":"10.1016/j.cclet.2025.111617","url":null,"abstract":"<div><div>The development of innovative strategies for inert B–H bond functionalization of carboranes and exploration of their potential applications represents a central task in organic chemistry. Here, we demonstrate the facile B–H bond functionalization in carboranes through a cage···I(III) interaction between a <em>nido</em>‑carborane cluster and a hypervalent iodine(III) unit. Both experimental and theoretical investigations reveal that the cage···I(III) interaction induces a charge transfer from the boron cage to the iodine moiety, which leads to a significant decrease of the negative charge at the B(9)–H site of <em>nido</em>‑carborane. This facilitates the activation of the B–H bond and subsequent chemical transformations. The unprecedented cage···I(III) interaction offers a similar B–H bond activation mode as metal mediation. Furthermore, the treatment of <em>nido</em>‑carboranes with the iodide(III) reagent of PhI(OAc)<sub>2</sub> affords <em>nido</em>‑carborane-phenyl iodonium zwitterions as versatile synthons, which enable the modular construction of exopolyhedral B–O, B–N, B–P, and B–S bonds of carborane derivatives. This approach provides an efficient and scalable synthetic platform for metal-free and site-selective B–H bond functionalization of <em>nido</em>‑carboranes under mild conditions. Notably, the developed 2D-3D fused structures can be used as ligands for the facile construction of novel boron cluster-fused hetero-polycyclic metal complexes in one step. These compounds demonstrate intriguing photophysical properties including aggregation-induced emission, tunable emission wavelength, and oxygen sensing.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"37 5","pages":"Article 111617"},"PeriodicalIF":8.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146186611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Carbon–metal bond homolysis-recombination enabling enantioconvergent carboxylation with CO2: A theoretical study 碳-金属键均解-重组实现CO2对映收敛羧基化的理论研究

IF 8.9 1区化学

Chinese Chemical Letters Pub Date : 2026-05-01 Epub Date: 2025-06-09 DOI: 10.1016/j.cclet.2025.111429

Qi Zhou , Cefei Zhang , Hui-Lin Luo , Chuan-Xi Nie , Changwei Hu , Jian-Heng Ye , Zhishan Su , Li-Li Liao , Da-Gang Yu

{"title":"Carbon–metal bond homolysis-recombination enabling enantioconvergent carboxylation with CO2: A theoretical study","authors":"Qi Zhou , Cefei Zhang , Hui-Lin Luo , Chuan-Xi Nie , Changwei Hu , Jian-Heng Ye , Zhishan Su , Li-Li Liao , Da-Gang Yu","doi":"10.1016/j.cclet.2025.111429","DOIUrl":"10.1016/j.cclet.2025.111429","url":null,"abstract":"<div><div>The generation of transient radical species <em>via</em> carbon–metal bond homolysis is extremely useful, which can be harnessed to promote useful and selective radical-type transformations by the combination of transition metal catalysis. We herein establish a carbon–metal bond homolysis/recombination model for the formation of enantiomerically enriched carbon-metal species, which accounts for the Ni-catalyzed enantioconvergent carboxylation of racemic benzyl ammonium salts with CO<sub>2</sub>. Theoretical studies suggest a distinct pathway involving a stereoinvertive nucleophilic substitution-type oxidative addition of racemic benzyl ammonium salts to Ni(0), forming a racemic benzyl Ni(II) intermediate. Subsequent C–Ni bond homolysis of one enantiomer enables the formation of a transient radical, followed by a dynamic rotation along C–C<sup>•</sup> bond and radical recombination forming another more thermodynamically favored enantiomer. Geometry analysis suggests less H–H repulsion between the benzyl group and chiral ligand in the more stable isomer. After the reduction and stereoretentive inner-sphere nucleophilic attack on CO<sub>2</sub> process, the desired enantiomerically enriched carboxylic acid product is generated. ETS-NOCV analysis reveals a significant back-donation interaction between the <em>d</em><sub>x2-y2</sub> orbital of Ni atom and the unoccupied <em>π</em>* orbital of CO<sub>2</sub> in inner-sphere transition state, thus effectively stabilizing the Ni–CO<sub>2</sub> complex and facilitating subsequent C–C bond formation. The theoretical calculations provide critical insights into the systematic development of transition metal-catalyzed asymmetric carboxylation, highlighting significant potential for broad applications in synthetic organic chemistry.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"37 5","pages":"Article 111429"},"PeriodicalIF":8.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146186604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

C2-Symmetric NN atropisomeric diphosphines: Synthesis and application in enantioselective dearomatization of heteroaryls c2对称神经网络atropisomer二膦：合成及其在杂芳基对映选择性脱芳反应中的应用

IF 8.9 1区化学

Chinese Chemical Letters Pub Date : 2026-05-01 Epub Date: 2025-06-09 DOI: 10.1016/j.cclet.2025.111430

Xiao-Kai Li , Si-Hao Fu , Yi Yue , Rui-Jing Pang , Jia Feng , Ren-Rong Liu

引用次数: 0

Red and near-infrared emissive nitrogen-sulfur co-doped carbonized nanoparticles for red laser-induced synergistic photothermal and photodynamic tumor therapy 红光和近红外发射氮硫共掺杂碳化纳米粒子用于红光激光诱导的协同光热和光动力肿瘤治疗

IF 8.9 1区化学

Chinese Chemical Letters Pub Date : 2026-05-01 Epub Date: 2025-06-24 DOI: 10.1016/j.cclet.2025.111501

Zhenjian Li , Xue Wu , Lingyun Li , Bingzhe Wang , Guichuan Xing , Yupeng Liu , Songnan Qu

{"title":"Red and near-infrared emissive nitrogen-sulfur co-doped carbonized nanoparticles for red laser-induced synergistic photothermal and photodynamic tumor therapy","authors":"Zhenjian Li , Xue Wu , Lingyun Li , Bingzhe Wang , Guichuan Xing , Yupeng Liu , Songnan Qu","doi":"10.1016/j.cclet.2025.111501","DOIUrl":"10.1016/j.cclet.2025.111501","url":null,"abstract":"<div><div>Metal-free nanoparticles capable of executing synergistic photothermal therapy (PTT) and photodynamic therapy (PDT) under the action of a single-wavelength laser have garnered considerable attention. Here, a novel type of nitrogen-sulfur co-doped carbon nanoparticles (TG-CNPs) was synthesized from taurine and genipin using a solvothermal method in dimethylformamide. The TG-CNPs, with an average size of approximately 25 nm, demonstrated red and near-infrared absorption/emission in aqueous solution. TG-CNPs exhibited negligible dark cytotoxicity, excellent biocompatibility, and remarkable lysosomal localization ability. Upon 655-nm laser irradiation, TG-CNPs exhibited strong photothermal performance with a photothermal conversion efficiency of 30 % along with the efficient generation of superoxide radicals (<sup>•</sup>O<sub>2</sub><sup>−</sup>). Leveraging the enhanced permeability and retention (EPR) effect, TG-CNPs facilitated passive targeting and accumulation at the tumor site. Notably, following a single round of 655-nm laser treatment, the tumors in the mice were completely eradicated, with no evidence of recurrence observed over the subsequent five months. This study introduces a promising metal-free, heteroatom-doped carbon nanoparticle platform for effective synergistic PTT/PDT in tumor treatment.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"37 5","pages":"Article 111501"},"PeriodicalIF":8.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146186717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

γ-C(sp3)-H acylation of aliphatic amines enabled by cooperative photoredox NHC/Pd catalysis 协同光氧化还原NHC/Pd催化实现脂肪胺γ-C(sp3)-H酰化

IF 8.9 1区化学

Chinese Chemical Letters Pub Date : 2026-05-01 Epub Date: 2025-06-18 DOI: 10.1016/j.cclet.2025.111484

Xin-Han Wang , Ying Huang , Chun-Lin Zhang , Song Ye

{"title":"γ-C(sp3)-H acylation of aliphatic amines enabled by cooperative photoredox NHC/Pd catalysis","authors":"Xin-Han Wang , Ying Huang , Chun-Lin Zhang , Song Ye","doi":"10.1016/j.cclet.2025.111484","DOIUrl":"10.1016/j.cclet.2025.111484","url":null,"abstract":"<div><div>The site-selective C(sp<sup>3</sup>)-H functionalization is of great importance in synthetic chemistry. However, <em>γ</em>-amino C(sp<sup>3</sup>)-H functionalization of aliphatic amines remains challenging. Herein, we develop an efficient <em>γ</em>-C(sp<sup>3</sup>)-H acylation of aliphatic amines by cooperative photoredox NHC/Pd catalysis. The process entails the following key steps: (i) photoinduced palladium-promoted formation of aryl radical, (ii) generation of transient <em>γ</em>-amino alkyl radical through aryl radical-mediated 1,7-HAT, (iii) single-electron oxidation of Breslow enolate intermediate to persistent ketyl radical, and (iv) radical/radical coupling of <em>γ</em>-amino alkyl radical with ketyl radical. The synthetic utility of this <em>γ</em>-amino C(sp<sup>3</sup>)-H acylation is illustrated by the conversion of readily available aliphatic amines to a diverse collection of <em>γ</em>-aminoketones, which serve as versatile building blocks to enable the synthesis of pyrrolines of interest in medicinal chemistry. The radical mechanism is supported by the results of various control experiments, <em>in situ</em> EPR analysis, radical trapping experiment, and isotopic labeling studies.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"37 5","pages":"Article 111484"},"PeriodicalIF":8.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146186676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Disorder–order transition of two-dimensional molecular networks by selenium doping 硒掺杂二维分子网络的无序跃迁

IF 8.9 1区化学

Chinese Chemical Letters Pub Date : 2026-05-01 Epub Date: 2025-09-23 DOI: 10.1016/j.cclet.2025.111874

Liangliang Cai , Xinyi Zhang , Jiayi Lu , Juan Xiang , Qiang Sun , Andrew T.S. Wee

{"title":"Disorder–order transition of two-dimensional molecular networks by selenium doping","authors":"Liangliang Cai , Xinyi Zhang , Jiayi Lu , Juan Xiang , Qiang Sun , Andrew T.S. Wee","doi":"10.1016/j.cclet.2025.111874","DOIUrl":"10.1016/j.cclet.2025.111874","url":null,"abstract":"<div><div>Geometrical configurations at the nanometer scale are inherently linked to electronic properties, offering exciting opportunity to engineer the latter through precise structural control. The honeycomb structure, a prominent geometry in two-dimensional materials like graphene, has become a versatile platform for advancing energy technologies, quantum computing, and nanoscale sensing. Achieving a perfect honeycomb network at large scale remains challenging but desired, especially when atomic defects and disorder can severely impact materials’ properties and performances. Intrinsic topological defects often persist due to the conformational flexibility of the precursor skeletons, which allows precursor monomers to deform despite variations in preparation parameters. To address this challenge, we employ a tripod molecular precursor, <em>p</em>TBPT, combined with ultrahigh vacuum on-surface synthesis. Networks comprising rings of different edges are initially formed after deposition of <em>p</em>TBPT on Cu (111) at room temperature to 420 K. At low coverage (∼0.015 monolayer) selenium doping, we achieve the fabrication of ordered honeycomb networks with much improved structural homogeneity. Selenium doping facilitated the formation of ordered two-dimensional metal-organic nanostructure from 360 K to 480 K. The disorder−order transition of molecular networks through selenium doping on Cu (111) is explored through high-resolution scanning tunneling microscopy (STM). A persistent homology method is resorted to quantify the degree of order of our patterns. The regulation of energy diagrams in the absence or presence of the selenium atom is revealed by density functional theory (DFT) calculations. These findings can enrich the on-surface synthesis toolbox of conformationally flexible precursors, for the design of ordered nanoarchitectures, and for future development of engineered honeycomb nanomaterials.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"37 5","pages":"Article 111874"},"PeriodicalIF":8.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146186576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancing the phosphorescence performance of organic doped system by carbonylation of guests 用客体羰基化方法增强有机掺杂体系的磷光性能

IF 8.9 1区化学

Chinese Chemical Letters Pub Date : 2026-05-01 Epub Date: 2025-08-11 DOI: 10.1016/j.cclet.2025.111706

Lei Wang , Jianing Zhang , Jin Xiong , Wenbo Dai , Miaochang Liu , Xiaobo Huang , Yuye Chai , Yunxiang Lei , Zhengxu Cai , Minyu Zhu

{"title":"Enhancing the phosphorescence performance of organic doped system by carbonylation of guests","authors":"Lei Wang , Jianing Zhang , Jin Xiong , Wenbo Dai , Miaochang Liu , Xiaobo Huang , Yuye Chai , Yunxiang Lei , Zhengxu Cai , Minyu Zhu","doi":"10.1016/j.cclet.2025.111706","DOIUrl":"10.1016/j.cclet.2025.111706","url":null,"abstract":"<div><div>The host-guest doped strategy has become the main method for constructing organic phosphorescence materials. In the doped system, guest molecules emit phosphorescence, therefore, improving the luminescence performance of guests is the key to optimizing the phosphorescence property of the doped materials. Herein, we designed to introduce the carbonyl group on the guest molecules. Carbonyl group can effectively promote n-π* transitions, thereby increasing the spin-orbit coupling (SOC) constant of the guests, ultimately improving the phosphorescence performance of the doped materials. Using the indazole derivative (IZ) as the initial guest, two other guests containing carboxyl group (IZ-CG) or ethoxycarbonyl group (IZ-EG) were successfully obtained. Further selected two small molecules and two polymers as the hosts to construct four doped systems. Among these doped systems, the phosphorescence performance of doped materials with IZ-CG or IZ-EG as the guest is significantly better than that of doped materials with IZ as the guest. The phosphorescence lifetime has increased by 2.3-5.0 times, and the phosphorescence quantum yield has increased by 3.0-5.7 times. Theoretical calculations and single crystal structures indicated that carbonyl groups can not only increase the SOC constant, but also enhance the intermolecular interactions of the guests. In addition, doped material can be effectively used for imaging subcutaneous and lymph nodes in mice, achieving a high signal-to-noise ratio.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"37 5","pages":"Article 111706"},"PeriodicalIF":8.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146186571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Photoexcited Ni-catalyzed regioselective cross-coupling of aryl chlorides with multifluoroarenes 光激发镍催化芳酰氯与多氟芳烃的区域选择性交叉偶联

IF 8.9 1区化学

Chinese Chemical Letters Pub Date : 2026-05-01 Epub Date: 2025-12-09 DOI: 10.1016/j.cclet.2025.112260

Jie Liu , Jialin Ming , Da-Gang Yu

引用次数: 0