Le Pharmacien Hospitalier最新文献

{"title":"Comment améliorer la réponse pharmaceutique lors d’un plan rouge ? Exemple des hospices civils de Lyon","authors":"C. Feutrier ,&nbsp;A. Terrier ,&nbsp;L. Gabilly ,&nbsp;M. Dhers ,&nbsp;J. Fiorina ,&nbsp;A. Nageotte ,&nbsp;P.-Y. Gueugniaud","doi":"10.1016/j.phhp.2010.07.009","DOIUrl":"10.1016/j.phhp.2010.07.009","url":null,"abstract":"<div><h3>Introduction</h3><p>Depuis de nombreuses années, les postes sanitaires mobiles ou PSM sont prépositionnés dans certains hôpitaux pour améliorer la prise en charge des victimes de catastrophe en extra-hospitalier. Cependant, peu de recommandations existent concernant la délivrance des produits sur le terrain et les expériences antérieures locales ont montré un temps de mise à disposition inapproprié aux besoins.</p></div><div><h3>Objectif</h3><p>L’équipe médico-pharmaceutique lyonnaise a conceptualisé un système de kits permettant, pour chacun d’eux, la prise en charge d’un patient pour un geste vital donné. L’objectif est d’évaluer la faisabilité et la durée de préparation de 30 kits lors de l’arrivée de l’équipe pharmaceutique au niveau du poste médical avancé.</p></div><div><h3>Résultats</h3><p>Un premier exercice a permis de tester ce dispositif auprès de dix pharmaciens et 15 préparateurs mobilisables répartis en six groupes. Le temps moyen de préparation des kits était de 45<!--> <!-->minutes.</p></div><div><h3>Discussion - Conclusion</h3><p>Des évolutions en termes de procédures, d’organisation, de matériels et de composition des malles sont apportées. Cette organisation sur le terrain présente un double intérêt : optimiser les temps de réponse par l’anticipation des besoins (objectif fixé à 30<!--> <!-->minutes) et limiter, au démarrage, une désorganisation éventuelle toujours préjudiciable.</p></div><div><h3>Introduction</h3><p>Emergency stocks (including PSM, the Mobile Emergency Units in French) have been placed in specific hospitals for many years, thus improving casualties’ assistance in case of disasters. However there are few recommendations about pharmaceuticals release on the ground and the previous local experiences showed an inappropriate time for the needs.</p></div><div><h3>Objective</h3><p>Therefore, the medical pharmaceutical team in Lyon worked out and set up a kit-system, each of those enabling assistance of one patient for one given vital gesture. The objective is to estimate the feasibility and the duration of preparation of 30 kits from the arrival of the pharmaceutical team to the Mobile Emergency Unit.</p></div><div><h3>Results</h3><p>A first exercise enabled to test this device with 10 pharmacists and 15 pharmacist assistants who can be mobilized, divided into six groups. The average time of 45<!--> <!-->minutes was necessary to set up the kits together.</p></div><div><h3>Discussion - Conclusion</h3><p>Modification of process, organization, material and composition of trunks were implemented. This organization on the ground has two advantages: the optimization of the response time through anticipation of the needs (goal: 30<!--> <!-->min) and the limitation of a possible prejudicial disorganization.</p></div>","PeriodicalId":100871,"journal":{"name":"Le Pharmacien Hospitalier","volume":"45 3","pages":"Pages 124-130"},"PeriodicalIF":0.0,"publicationDate":"2010-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.phhp.2010.07.009","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85123042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"L’argent dans les dispositifs médicaux : marketing ou réel intérêt clinique ?","authors":"C. Fontenoy ,&nbsp;K.-O. Sellal","doi":"10.1016/j.phhp.2010.07.010","DOIUrl":"10.1016/j.phhp.2010.07.010","url":null,"abstract":"<div><h3>Objectif</h3><p>Ce travail a pour objectif de faire une synthèse des données concernant l’usage au cours du temps de l’argent dans les dispositifs médicaux et de discuter du niveau de validation méthodologique de son intérêt clinique en tant qu’adjuvant dans les dispositifs médicaux en insistant sur son usage plus récent et dans son application dans le domaine des plaies et de leur cicatrisation.</p></div><div><h3>Méthode</h3><p>Nous avons effectué une revue de la littérature et avons utilisé les fiches techniques des sociétés commercialisant ces dispositifs. Les études randomisées et contrôlées, multicentriques ou les avis d’experts ont été essentiellement retenus, sauf concernant les dispositifs médicaux hors pansements, ou la discussion sur les notions très récentes de propriétés procicatrisantes ou anti-inflammatoires de l’argent.</p></div><div><h3>Résultats et discussion</h3><p>Les résultats varient d’un dispositif à l’autre avec cependant, pour chaque dispositif, des différences significatives concernant la colonisation bactérienne. Concernant le soin des plaies, seul un petit nombre d’études montre des différences significatives d’efficience entre les pansements ou topiques contenant de l’argent et les contrôles utilisés. Ces travaux de recherche ont également révélé une nouvelle piste pouvant expliquer les propriétés procicatrisantes et anti-inflammatoires des nanoparticules d’argent.</p></div><div><h3>Objective</h3><p>The aim of this paper is to make a review of all medical devices, which contain silver, and to extract data concerning the use of silver in the medical devices. We discuss the level of methodological validation of silver in clinical use and notably in its application in wound healing.</p></div><div><h3>Method</h3><p>A review of literature was conducted and technical documentation of laboratories was used. The review included only controlled, randomised trials, multicenter study or expert opinion for the evaluation of effectiveness of silver dressing except for others silver contain devices and for the new approach of the action of silver in reduction inflammation.</p></div><div><h3>Results and discussion</h3><p>Results are variable from a medical device to the other one with always positives results concerning bacterial colonization. For wound devices, only few studies show significant differences in wound healing between control and test. However, these results have given insight into a new action of silver and we showed that silver nanoparticles exert positive effects through reduction in wound inflammation.</p></div>","PeriodicalId":100871,"journal":{"name":"Le Pharmacien Hospitalier","volume":"45 3","pages":"Pages 131-141"},"PeriodicalIF":0.0,"publicationDate":"2010-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.phhp.2010.07.010","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84848373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Revue des traitements : maladie d’Alzheimer","authors":"F. Lagrange","doi":"10.1016/j.phhp.2010.07.014","DOIUrl":"10.1016/j.phhp.2010.07.014","url":null,"abstract":"","PeriodicalId":100871,"journal":{"name":"Le Pharmacien Hospitalier","volume":"45 3","pages":"Page 100"},"PeriodicalIF":0.0,"publicationDate":"2010-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.phhp.2010.07.014","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83429796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"B. Édouard","doi":"10.1016/j.phhp.2010.07.001","DOIUrl":"10.1016/j.phhp.2010.07.001","url":null,"abstract":"","PeriodicalId":100871,"journal":{"name":"Le Pharmacien Hospitalier","volume":"45 3","pages":"Page 153"},"PeriodicalIF":0.0,"publicationDate":"2010-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.phhp.2010.07.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84667593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"La revue du web","authors":"","doi":"10.1016/j.phhp.2010.09.002","DOIUrl":"https://doi.org/10.1016/j.phhp.2010.09.002","url":null,"abstract":"","PeriodicalId":100871,"journal":{"name":"Le Pharmacien Hospitalier","volume":"45 3","pages":"Page 158"},"PeriodicalIF":0.0,"publicationDate":"2010-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.phhp.2010.09.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137285957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Préparation centralisée des poches de nutrition parentérale : Intérêt de l’utilisation d’un automate de laboratoire pour le contrôle physicochimique","authors":"S. Magne,&nbsp;M.-O. Deneuville,&nbsp;F. Lemare,&nbsp;M.-L. Brunet,&nbsp;A. Dauphin,&nbsp;L. Harcouët","doi":"10.1016/j.phhp.2010.07.011","DOIUrl":"10.1016/j.phhp.2010.07.011","url":null,"abstract":"<div><h3>Introduction</h3><p>Une unité centralisée de préparation de mélanges pédiatriques de nutrition parentérale (NP) a été mise en place à la pharmacie du groupe hospitalier Cochin – Saint-Vincent de Paul (Paris).</p></div><div><h3>Objectif</h3><p>L’objectif de ce travail est de décrire et évaluer les performances d’un automate de laboratoire pour le contrôle physicochimique des préparations de NP binaires (sans lipides) réalisées dans notre unité.</p></div><div><h3>Méthode</h3><p>La validation des dosages sur l’automate de laboratoire Olympus AU400^® a été effectuée sur sept préparations de concentrations croissantes en Na⁺, K⁺, Cl⁻, Ca²⁺, Mg²⁺ et glucose.</p></div><div><h3>Résultats et discussion</h3><p>Pour chaque paramètre, la reproductibilité et la répétabilité sont : CV % toujours inférieur à 3,5 %, biais inférieur à 9 % sauf pour les valeurs basses de Cl⁻. L’effet matrice n’est pas significatif en comparant les résultats de mesure des sept préparations à chaque élément dosé indépendamment et dilué uniquement dans de l’eau distillée.</p></div><div><h3>Conclusion</h3><p>Le recours à l’automate de laboratoire est simple, adapté au dosage rapide des principaux constituants des préparations de NP binaires (glucose, électrolytes principaux) ; avec un coût total évalué à 3 % du coût de nos préparations.</p></div><div><h3>Introduction</h3><p>A pediatric parenteral nutrition (PN) unit opened recently in Cochin Hospital Pharmacy (Paris, France).</p></div><div><h3>Objectives</h3><p>The objectives are describing the main quality controls (QC) in this unit and evaluating efficiency of a laboratory automation system (Olympus AU400^®) for dosing components in the bags.</p></div><div><h3>Method</h3><p>To validate the automation system, we tested repetability and reproductibility using bags with growing concentrations of Na⁺, K⁺, Cl⁻, Ca²⁺, Mg²⁺ and glucose.</p></div><div><h3>Results and discussion</h3><p>CV% was always less than 3.5% and bias less than 9 % except for lower values of Cl⁻. Moreover, matrix effect is not significant, when results of PN are compared for each parameters to measurements without matrix (only diluted in distilled water).</p></div><div><h3>Conclusion</h3><p>Laboratory automation system is simple, reliable and adapted to rapid dosage of numerous nutriments in PN bags and the total cost of chemical control amounts 3% of the PN bags cost.</p></div>","PeriodicalId":100871,"journal":{"name":"Le Pharmacien Hospitalier","volume":"45 3","pages":"Pages 101-107"},"PeriodicalIF":0.0,"publicationDate":"2010-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.phhp.2010.07.011","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81137458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"F. Lagrange","doi":"10.1016/j.phhp.2010.07.004","DOIUrl":"10.1016/j.phhp.2010.07.004","url":null,"abstract":"","PeriodicalId":100871,"journal":{"name":"Le Pharmacien Hospitalier","volume":"45 3","pages":"Page 154"},"PeriodicalIF":0.0,"publicationDate":"2010-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.phhp.2010.07.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74126990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analyses d’articles–septembre 2010","authors":"","doi":"10.1016/j.phhp.2010.07.013","DOIUrl":"https://doi.org/10.1016/j.phhp.2010.07.013","url":null,"abstract":"","PeriodicalId":100871,"journal":{"name":"Le Pharmacien Hospitalier","volume":"45 3","pages":"Pages 150-152"},"PeriodicalIF":0.0,"publicationDate":"2010-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.phhp.2010.07.013","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137224562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cherchez l’erreur","authors":"T. Berod","doi":"10.1016/j.phhp.2010.07.006","DOIUrl":"10.1016/j.phhp.2010.07.006","url":null,"abstract":"","PeriodicalId":100871,"journal":{"name":"Le Pharmacien Hospitalier","volume":"45 3","pages":"Page 99"},"PeriodicalIF":0.0,"publicationDate":"2010-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.phhp.2010.07.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"111956250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Revue des traitements : maladie d’Alzheimer","authors":"F. Lagrange","doi":"10.1016/j.phhp.2010.07.015","DOIUrl":"https://doi.org/10.1016/j.phhp.2010.07.015","url":null,"abstract":"","PeriodicalId":100871,"journal":{"name":"Le Pharmacien Hospitalier","volume":"45 3","pages":"Pages 142-149"},"PeriodicalIF":0.0,"publicationDate":"2010-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.phhp.2010.07.015","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137224542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}