La Presse Médicale Formation最新文献

{"title":"Le traitement de la maladie de Crohn en 2024","authors":"Pauline Wils","doi":"10.1016/j.lpmfor.2025.100626","DOIUrl":"10.1016/j.lpmfor.2025.100626","url":null,"abstract":"<div><div>– En France, cinq biothérapies (l’adalimumab et l’infliximab (des anti-TNF), le vedolizumab (un anti-intégrine), l’ustekinumab (un anti-interkeukin-(IL)12/23) et le risankizumab (un anti-IL23p19)) et un inhibiteur des JAK (janus kinase) ont l’autorisation de mise sur le marché dans la maladie de Crohn (MC).</div><div>– Seuls les anti-TNF peuvent être prescrits en France en 1^re ligne dans la MC.</div><div>– Les traitements d’efficacité avancée, débutés précocement, semblent modifier l’histoire naturelle de la maladie de Crohn.</div><div>– La rémission profonde, définie aujourd’hui par la rémission clinique, endoscopique et transmurale (en imagerie en coupes), permet d’améliorer l’histoire naturelle de la maladie et d’éviter des complications.</div><div>– Le traitement des formes sténosantes ou fistulisantes intra-abdominales de maladie de Crohn nécessite une approche multidisciplinaire (gastro-entérologue, radiologue et chirurgien digestif)</div><div>– Les thérapies complémentaires non médicamenteuses comme l’activité physique et le soutien psychologique sont importants pour améliorer le stress, les symptômes anxiodépressifs ou la fatigue.</div><div>– Les stratégies thérapeutiques en cours d’évaluation dans la maladie de Crohn évoluent vers la combinaison des traitements d’efficacité avancée (combiothérapie)</div></div><div><div>– In France, five biologics (adalimumab and infliximab (anti-TNFs), vedolizumab (anti-integrin), ustekinumab (anti-interleukin (IL)-12/23), and risankizumab (anti-IL23p19)) as well as a Janus kinase inhibitor (JAKi) are approved in Crohn's disease (CD).</div><div>– Only anti-TNF agents are prescribed as first-line therapy for CD in France.</div><div>– Advanced therapies, initiated early, appear to modify the natural course of CD.</div><div>– Deep remission, based on clinical, endoscopic, and transmural remission, improves the natural history of the disease and prevents complications.</div><div>– The treatment of stricturing or fistulizing CD requires a multidisciplinary approach involving a gastroenterologist, radiologist, and surgeon.</div><div>– Complementary non-pharmacological therapies, such as physical activity and psychological support, are important to alleviate stress, anxiety-depressive symptoms, and fatigue.</div><div>– Therapeutic strategies currently under evaluation in CD are moving toward the combination of advanced therapies.</div></div>","PeriodicalId":100859,"journal":{"name":"La Presse Médicale Formation","volume":"6 2","pages":"Article 100626"},"PeriodicalIF":0.0,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143687719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Le médecin doit être un protecteur des enfants victimes de violences physiques et psychologiques","authors":"Gilles Lazimi ,&nbsp;Edwige Antier","doi":"10.1016/j.lpmfor.2025.100597","DOIUrl":"10.1016/j.lpmfor.2025.100597","url":null,"abstract":"<div><div>Les médecins généralistes et les pédiatres sont en première ligne pour protéger les enfants des violences à prétextes éducatifs, que l’on appelle « Violences Éducatives Ordinaires (VEO) ». Le médecin a un rôle majeur tout au long de l’enfance pour repérer, pour accompagner les parents et les aider à ne plus recourir à des violences éducatives ordinaires. Des consultations répétées permettent de sensibiliser les parents au développement de l’enfant et à l’importance d’une éducation sans violence.</div></div><div><div>General practitioners and pediatricians are on the frontline to protect children who are victims of physical and psychological violence with educational pretexts which are called “Ordinary Educational Violences (OEV)”. The family doctor has a major role throughout childhood to identify, support parents and help them to no longer use Ordinary Educational Violences. Repeated consultations make it possible to raise parents’ awareness of child development and the importance of an education without violence.</div></div>","PeriodicalId":100859,"journal":{"name":"La Presse Médicale Formation","volume":"6 1","pages":"Article 100597"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143552464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quelles conséquences ont les VEO en matière de santé et de développement des enfants ?","authors":"Gilles Lazimi ,&nbsp;Edwige Antier","doi":"10.1016/j.lpmfor.2025.100596","DOIUrl":"10.1016/j.lpmfor.2025.100596","url":null,"abstract":"<div><div>Les violences éducatives ordinaires (VEO) sont susceptibles d’avoir des conséquences profondes et durables sur la santé et le développement ultérieur des enfants. Des recherches ont montré que ces pratiques nuisent au bien-être psychologique, au développement cognitif, aux compétences sociales et à la santé physique des enfants. Les enfants qui grandissent dans des environnements violents sont plus susceptibles de reproduire ces comportements avec leurs propres enfants, perpétuant ainsi un cycle intergénérationnel de violence.</div></div><div><div>Violences, Ordinary Educational Violence (VOE) may have profound and lasting consequences on children's health and development. Some researches have shown that these practices harm children's psychological well-being, cognitive development, social skills, and physical health. Children who grow up in violent environments are more likely to reproduce these behaviors with their own children, thus perpetuating an intergenerational cycle of violence.</div></div>","PeriodicalId":100859,"journal":{"name":"La Presse Médicale Formation","volume":"6 1","pages":"Article 100596"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143552463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Les Violences Educatives Ordinaires (VEO) et le rôle des infirmières puéricultrices : prévention et soutien à la parentalité","authors":"Elodie Emo ,&nbsp;Michèle Prados ,&nbsp;Claire Royer de la Bastie","doi":"10.1016/j.lpmfor.2025.100598","DOIUrl":"10.1016/j.lpmfor.2025.100598","url":null,"abstract":"<div><div>La prévention des VEO et les actions de promotion et d’éducation à la santé représentent des enjeux majeurs pour le développement sain des enfants et le bien-être des familles. Les infirmières puéricultrices, avec leur expertise et leur présence dans divers environnements de vie de l’enfant, jouent un rôle crucial dans cette prévention.</div></div><div><div>Ordinary Educational Violences (EOV) prevention, health promotion and education actions represent major challenges for the healthy development of children and the well-being of families. Childcare nurses, with their expertise and presence in various child living environments, play a crucial role in this prevention.</div></div>","PeriodicalId":100859,"journal":{"name":"La Presse Médicale Formation","volume":"6 1","pages":"Article 100598"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143552465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pseudo polyarthrite rhizomélique : mise au point","authors":"André Ramon ,&nbsp;Hélène Greigert ,&nbsp;Paul Ornetti ,&nbsp;Jean-Francis Maillefert ,&nbsp;Bernard Bonnotte ,&nbsp;Maxime Samson","doi":"10.1016/j.lpmfor.2024.10.002","DOIUrl":"10.1016/j.lpmfor.2024.10.002","url":null,"abstract":"<div><div>La pseudo polyarthrite rhizomélique (PPR) est caractérisée par des douleurs inflammatoires des ceintures pelvienne et scapulaire associées à un syndrome inflammatoire biologique chez les patients âgés de plus de 50 ans. Elle est associée à une artérite à cellules géantes (ACG) dans 16 à 21 % des cas. La fréquence importante des affections se manifestant initialement sous la forme d’une PPR (PPR-<em>like</em>) justifie, chez un patient ayant des douleurs inflammatoires des ceintures, de chercher et d’éliminer des diagnostics différentiels car il n’existe à l’heure actuelle aucun marqueur biologique spécifique de la maladie. Le diagnostic de PPR est donc un diagnostic d’élimination. Dans ce contexte, l’imagerie a pris une place majeure pour aider le clinicien dans la démarche diagnostique. Le traitement de la PPR repose sur la corticothérapie par voie générale avec une décroissance progressive sur une durée de 12 mois. Ces dernières années ont été marquées par le développement de traitements à visée d’épargne cortisonique, dont l’objectif est de limiter la survenue d’effets indésirables liés à la corticothérapie dans cette population âgée présentant souvent des comorbidités cardio-vasculaires, métaboliques et/ou fracturaires. Cette revue a pour but de fournir aux cliniciens les caractéristiques épidémiologiques, cliniques, d’imageries et thérapeutiques de la PPR.</div></div><div><div>Polymyalgia rheumatica (PMR) is a rheumatologic condition characterized by inflammatory pain of the pelvic and scapular girdles associated with a biological inflammatory syndrome in patients<!--> <!-->&gt;<!--> <!-->50 years old. It is associated with giant cell arteritis (GCA) in 16-21 % of cases. There is no specific biological test for PMR. The diagnosis is based on the exclusion of diseases that could mimic PMR. In recent years, imaging has undergone significant development helping clinicians for the diagnostic. Treatment of PMR is based on glucocorticoid therapy, which is gradually tapered over 12 months. Over the last few years, assessment of glucocorticoid-sparing agents has been developed, to reduce the occurrence of glucocorticoid associated side effect in an elderly population, who often has cardiovascular, metabolic and/or fracture-related comorbidities. The aim of this review is to provide clinicians an overview of the epidemiological, clinical, imaging and therapeutic features of PMR.</div></div>","PeriodicalId":100859,"journal":{"name":"La Presse Médicale Formation","volume":"6 1","pages":"Article 100594"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143552461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CV1 / Sommaire","authors":"","doi":"10.1016/S2666-4798(25)00011-4","DOIUrl":"10.1016/S2666-4798(25)00011-4","url":null,"abstract":"","PeriodicalId":100859,"journal":{"name":"La Presse Médicale Formation","volume":"6 1","pages":"Article 100605"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143552456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment accompagner l’interdiction par la loi des « Violences éducatives ordinaires » ? Des 1000 premiers jours aux assises de la santé de l’enfant","authors":"Adrien Taquet","doi":"10.1016/j.lpmfor.2025.100599","DOIUrl":"10.1016/j.lpmfor.2025.100599","url":null,"abstract":"<div><div>Le 10 juillet 2019, la France inscrivait enfin dans ses textes, et faisait annoncer dans ses mairies, cette évidence que « l’autorité parentale s’exerce sans violences physiques ou psychologiques » faisant de notre pays l’un des derniers pays en Europe à affirmer dans les textes un impératif développemental comme norme sociale. Mais la loi ne peut pas tout. Et surtout, la loi doit être accompagnée pour être comprise, pour être apprivoisée, pour être endossée, pour être appliquée tout simplement. La prévention des violences, quelles qu’elles soient, doit continuer de figurer au premier rang des priorités politiques, et au-delà de notre combat en tant que société.</div></div><div><div>On July 10, 2019, France finally included in its texts, and announced in its town halls, this obvious fact that “parental authority must be exercised without physical or psychological violence”. It thus made our country one of the last countries in Europe to affirm in its texts a developmental imperative as a social norm. But the law cannot do everything. And above all, the law must be accompanied in order to be understood, to be tamed, to be endorsed, to be applied quite simply. The prevention of violence, whatever it may be, must continue to be at the top of political priorities, and beyond our societal struggles.</div></div>","PeriodicalId":100859,"journal":{"name":"La Presse Médicale Formation","volume":"6 1","pages":"Article 100599"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143552466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sommaire","authors":"","doi":"10.1016/S2666-4798(25)00030-8","DOIUrl":"10.1016/S2666-4798(25)00030-8","url":null,"abstract":"","PeriodicalId":100859,"journal":{"name":"La Presse Médicale Formation","volume":"6 1","pages":"Article 100624"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143552458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ours redaction","authors":"","doi":"10.1016/S2666-4798(25)00013-8","DOIUrl":"10.1016/S2666-4798(25)00013-8","url":null,"abstract":"","PeriodicalId":100859,"journal":{"name":"La Presse Médicale Formation","volume":"6 1","pages":"Article 100607"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143552457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alerte obésité","authors":"Jean-Michel Lecerf (Endocrinologue)","doi":"10.1016/j.lpmfor.2024.09.009","DOIUrl":"10.1016/j.lpmfor.2024.09.009","url":null,"abstract":"","PeriodicalId":100859,"journal":{"name":"La Presse Médicale Formation","volume":"6 1","pages":"Article 100592"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143552460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}