Journal of Pediatric Surgery Open最新文献

{"title":"Prenatal ovarian torsion: Diagnosis and management in the newborn","authors":"Stefanie Devriendt ,&nbsp;Stijn Heyman ,&nbsp;Paul Leyman ,&nbsp;Conny Meeussen ,&nbsp;Dirk Vervloessem","doi":"10.1016/j.yjpso.2024.100117","DOIUrl":"https://doi.org/10.1016/j.yjpso.2024.100117","url":null,"abstract":"<div><h3>Introduction</h3><p>Prenatal ovarian torsion (POT) is a clinical condition that has been described before, but is little known and up until now lacks clear guidelines on management. Prenatal discovery of an abdominal mass or cyst can lead to a lot of stress and anxiety with parents. Knowing that POT is a benign condition with marked sonographic-pathologic correlations, our aim is to define the clinical entity and radiological features of a POT with the largest population to date and set up clear guidelines on its management.</p></div><div><h3>Materials and methods</h3><p>We retrospectively collected data from three different pediatric surgical units over a period of 10 years (between 2008-2018). All patients treated for POT were included. Postnatal radiological imaging as well as clinicopathological information was collected and correlated with our diagnostic criteria.</p></div><div><h3>Results</h3><p>We recovered data from a total of 35 patients. A fluid-debris level on ultrasonography (US) was shown to be a specific feature of torsion and was present in all patients. All patients underwent laparoscopic resection of the cyst at a mean age of 73 days. Upon laparoscopy, 16 patients showed signs of adhesions to the cyst. Pathological findings showed the lack of any remaining ovarian tissue in all of the cases.</p></div><div><h3>Conclusions</h3><p>Prenatal ovarian torsion is a condition with distinctive radiological features, the main being a fluid-debris level on sonography. Laparoscopic resection of the cyst has proven to be safe and should be considered in all patients diagnosed with POT.</p></div>","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"6 ","pages":"Article 100117"},"PeriodicalIF":0.0,"publicationDate":"2024-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949711624000029/pdfft?md5=55d8d190ce21faa6a262157539e7587c&pid=1-s2.0-S2949711624000029-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139503828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anorectal malformation: Audit of management in a major tertiary institution in Ghana","authors":"Fareeda Galley ,&nbsp;Arkoh Ebenezer Ameyaw ,&nbsp;Abiboye Yifieyeh ,&nbsp;Afua Hesse","doi":"10.1016/j.yjpso.2024.100116","DOIUrl":"https://doi.org/10.1016/j.yjpso.2024.100116","url":null,"abstract":"<div><h3>Background</h3><p>Anorectal malformation (ARM) remains a significant challenge to the child and paediatric surgeons. Its rarity is relative in Sub-Saharan Africa, where there are few specialized centres for management. This study aimed to describe the presentations, management, and preliminary outcomes of ARM in a major specialized centre.</p></div><div><h3>Methods</h3><p>A prospective observational study, with a two-year follow-up was conducted for children (up to 15 years) who presented with ARM at the Paediatric Surgery Unit between November 2020 and July 2021.</p></div><div><h3>Results</h3><p>Sixty-one (61) patients (M: <em>F</em> = 1:0.96) were studied. 28.27 % of the ARM's were detected on day one of birth. More than two thirds of the cohort (70.5 %) was first detected by mothers. The remainder (29.5 %) were detected by health professionals. Majority, 88.2 %, presented late (&gt;24hours). 34(55.4 %) presented in a stable state, 20(32.79 %) with acute intestinal obstruction and 4(6.56 %) with sepsis. Associated congenital anomalies were observed in 7(11.48 %) of patients. All the children had a staged procedure (colostomy, PSARP and closure of colostomy). The mean duration between colostomy creation and PSARP was 7.02 +/- 2.05 months, while the mean duration between PSARP and colostomy reversal was eight months. The complication and mortality rates after all the staged procedures were 39.3 % and 2.2 %, respectively. 5.2 % had persistent faecal soiling while 3.5 % had persistent constipation at 2 years. There were no anal strictures or rectal prolapse.</p></div><div><h3>Conclusion</h3><p>Surgical outcomes of children with ARM are generally good, although there were late and unstable presentations to the hospital. Late identification of ARM by health professionals lead to late presentation.</p></div>","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"5 ","pages":"Article 100116"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949711624000017/pdfft?md5=375caf6f8b6469b7e8523f9285d447f2&pid=1-s2.0-S2949711624000017-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139435857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advances in the study of long non-coding RNAs in Hirschsprung disease","authors":"L Huang ,&nbsp;M He ,&nbsp;YM Liu ,&nbsp;Z Jin","doi":"10.1016/j.yjpso.2023.100114","DOIUrl":"10.1016/j.yjpso.2023.100114","url":null,"abstract":"<div><p>Long non-coding RNAs (lncRNAs) are a class of non-protein-coding RNAs with transcript lengths &gt;200 nucleotides. They play important roles in the regulation of gene expression through epigenetic mechanisms, such as chromatin remodeling, post-transcriptional processing, and acting as miRNA sponges. Recently, the involvement of lncRNAs in the pathogenesis of many diseases has been demonstrated. In this paper, we briefly review the latest progress in understanding the role of lncRNAs in the development of Hirschsprung disease (HSCR).</p></div>","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"5 ","pages":"Article 100114"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949711623001119/pdfft?md5=36b42b0b4e1be9bdc3c8ba97c675d8fa&pid=1-s2.0-S2949711623001119-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139018372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial Board Page","authors":"","doi":"10.1016/S2949-7116(24)00007-8","DOIUrl":"https://doi.org/10.1016/S2949-7116(24)00007-8","url":null,"abstract":"","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"5 ","pages":"Article 100122"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949711624000078/pdfft?md5=cea35b554764a4bde2c81079aacf5461&pid=1-s2.0-S2949711624000078-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139549754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancing care coordination & patient and family engagement in pediatric surgery through enhanced recovery after surgery® protocols","authors":"Jennifer Y Lam,&nbsp;Natashia M Seemann","doi":"10.1016/j.yjpso.2023.100112","DOIUrl":"10.1016/j.yjpso.2023.100112","url":null,"abstract":"<div><p>The uptake of pediatric Enhanced Recovery After Surgery (ERAS®) protocols has gradually increased over the years. While many teams have accepted ERAS® protocols for their improvement in clinical outcomes, there are further domains of care that may be strengthened by the adoption of ERAS®. Enhanced Recovery After Surgery® principles provide the framework for coordinating care among the increasingly complex clinical team required to look after pediatric patients. Engaging our pediatric patients and their families throughout the ERAS® process has multiple benefits. Involving patients in the development and implementation process of ERAS® protocols creates more robust guidelines. In addition, engaged patients have greater compliance to recommendations and improved outcomes. The adoption of pediatric ERAS® guidelines enhances pediatric surgical outcomes, establishes strong teamwork, communication and care coordination and reinforces the patient and family needs as a top priority.</p></div>","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"5 ","pages":"Article 100112"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949711623001090/pdfft?md5=4c87bd92766887676c1e7d332dc676b8&pid=1-s2.0-S2949711623001090-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139014599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sexual function in adolescents and young adults (AYA) with Bladder exstrophy-epispadias complex: Influence of the incontinence","authors":"Lara Merino-Mateo ,&nbsp;Daniel Cabezalí Barbancho ,&nbsp;Cristina Tordable Ojeda ,&nbsp;Andrés Gómez Fraile","doi":"10.1016/j.yjpso.2023.100078","DOIUrl":"10.1016/j.yjpso.2023.100078","url":null,"abstract":"<div><h3>Background</h3><p>Bladder exstrophy-epispadias complex (BEEC) is the most severe congenital anomaly involving the urinary tract. Currently, there is a growing interest in the long-term outcomes and their impact on quality of life (QoL).</p></div><div><h3>Methods</h3><p>Our aim was to determine the incidence of urinary incontinence and whether it affects sexual function. The study population included BEEC patients &gt;18 years treated at a specialized third-level hospital. We contacted them via telephone and emailed a voluntary online questionnaire which was anonymously self-completed. The online test included validated questionnaires to assess the following parameters: incontinence (ICIQ-SF), LUTS (ICIQ-FLUTS/IPSS) and sexual function (FSH/FSM2). Answers of the questionnaires were collected into a database for further evaluation. Statistical significance was defined by <em>p</em> &lt; .05.</p></div><div><h3>Results</h3><p>Among the thirteen patients (7 men and 6 women) who answered the questionnaire the median score on ICIQ-SF was 6/21. Based on that questionnaire only 4 patients (30.8 %) were classified as continent (ICIQ-SF = 0). However, when directly asked if they were able to stay dry in their day-to-day life, 61.5 % responded affirmatively, a number that doubled those who were considered continent according to the ICIQ-SF test. Incontinence was associated with an increased sexual dysfunction, having a correlation with low satisfaction in men and diminished libido and lubrication in women.</p></div><div><h3>Conclusions</h3><p>In the present study, we found a high incontinence rate, which is discrepant with the self-perception of day-to-day dryness. In addition, our data showed that incontinence is linked to a diminished sexual function.</p></div>","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"5 ","pages":"Article 100078"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949711623000758/pdfft?md5=86575c101fa9b06e65a9d5feb1703d75&pid=1-s2.0-S2949711623000758-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135706418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection limit of computed tomography for hepatoblastoma pulmonary metastases: Based on total resection using indocyanine green fluorescence","authors":"Yukihiro Tsuzuki ,&nbsp;Norihiko Kitagawa ,&nbsp;Masato Shinkai ,&nbsp;Kyoko Mochizuki ,&nbsp;Hidehito Usui ,&nbsp;Kazuyoshi Okumura ,&nbsp;Yuma Yagi ,&nbsp;Akio Kawami ,&nbsp;Masakatsu Yanagimachi ,&nbsp;Kumiko Nozawa ,&nbsp;Mio Tanaka","doi":"10.1016/j.yjpso.2024.100118","DOIUrl":"https://doi.org/10.1016/j.yjpso.2024.100118","url":null,"abstract":"<div><h3>Background</h3><p>Intraoperative search for small pulmonary metastases of hepatoblastoma has been challenging; therefore, it has been difficult to determine the true detection limit of computed tomography (CT). This is the first report on the detection limit of CT for hepatoblastoma pulmonary metastases in patients who underwent resection of hepatoblastoma pulmonary metastases using indocyanine green fluorescence (ICGF).</p></div><div><h3>Methods</h3><p>We retrospectively reviewed the CT images of patients who underwent resection of hepatoblastoma pulmonary metastases using ICGF between January 2013 and November 2021 at a single children's hospital and compared them with pathological findings.</p></div><div><h3>Results</h3><p>Overall, 757 nodules were resected from 20 cases and 75 thoracotomies; 411 nodules were considered for the study and 286 were pathologically positive. The number of nodules classified by size in the pathological sections and the probability of CT detection were as follows: &lt; 2 mm: CT-positive/pathology-positive, 43/144, 29.9 %; ≥ 2 and &lt; 3 mm: 5/10, 50 %; ≥ 3 and &lt; 4 mm: 20/27, 74.1 %; ≥ 4 and &lt; 5 mm: 15/16, 93.8 %; ≥ 5 mm: 87/89, 97.8 %. Of 286 pathology-positive nodules, 59.4 % were CT-positive. With a cut-off value of 3 mm for tumor size, the proportion of CT-positive nodules was 92.4 %. Of 177 CT-positive nodules, 170 were pathologically positive.</p></div><div><h3>Conclusions</h3><p>More than 90 % of nodules &gt; 3 mm were detectable on CT, whereas less than 30 % of pathologically positive nodules &lt; 2 mm could be detected. In children with hepatoblastoma, a CT-positive pulmonary nodule, even if minute, is likely to be malignant and metastasis should be suspected.</p></div>","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"5 ","pages":"Article 100118"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949711624000030/pdfft?md5=c57c7bde9009833d6784ef6021a64393&pid=1-s2.0-S2949711624000030-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139487407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The time is right to implement Enhanced Recovery After Surgery (ERAS) broadly across pediatric surgery","authors":"Gregg Nelson","doi":"10.1016/j.yjpso.2023.100113","DOIUrl":"https://doi.org/10.1016/j.yjpso.2023.100113","url":null,"abstract":"<div><p>ERAS is a global surgical quality improvement program that has demonstrated benefit across numerous surgical disciplines in terms of both clinical outcome improvements for patients and cost savings for the healthcare system. Successful implementation of ERAS is contingent on a well-functioning multidisciplinary team that uses audit to iterate towards increased ERAS protocol compliance. Although pediatric surgery was slow initially to adopt ERAS, there have been several important developments over the last 5 years including publication of the first ERAS® Society guideline in neonatal intestinal surgery and formation of the Pediatric ERAS® Society. The time is right to implement ERAS broadly across pediatric surgery.</p></div>","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"5 ","pages":"Article 100113"},"PeriodicalIF":0.0,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949711623001107/pdfft?md5=dfb7f2cc367dee55ebb0cf3c010eb8ea&pid=1-s2.0-S2949711623001107-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138839665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Innovative regenerative therapy for refractory postoperative esophageal anastomotic stenosis in children","authors":"Yasushi Fuchimoto","doi":"10.1016/j.yjpso.2023.100110","DOIUrl":"https://doi.org/10.1016/j.yjpso.2023.100110","url":null,"abstract":"<div><p>Autologous oral mucosa-derived epithelial cell sheet transplantation was devised as a new treatment for refractory postoperative anastomotic stenosis in patients with congenital esophageal atresia (CEA) and congenital esophageal stenosis (CES). Transplantation therapy was performed on three patients with refractory postoperative anastomotic stenosis who had undergone endoscopic balloon dilatation (EBD) at least twice in one year and at least five times in total. Epithelial cell sheets were prepared from the patients' oral mucosa and transplanted over the esophageal wounds caused by EBD using a specially developed transplantation device. After transplantation, the patients were followed for 48 weeks. Subject 1 underwent two transplantations and showed temporary improvement in stenosis, but required periodic EBD and eventually had the stenotic area removed. Subject 2 did not require EBD for more than two years post-transplantation; Subject 3, until one year after transplantation. Both Subject 2 and Subject 3 experienced improvement in the passage of food and drink and were able to consume a regular diet as opposed to a full liquid diet. These results suggest that cell sheet transplantation therapy is effective in some cases.</p><p>Trial registration: UMIN, UMIN000034566, registered 19 October 2018, https://upload.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000039393.</p></div>","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"5 ","pages":"Article 100110"},"PeriodicalIF":0.0,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949711623001077/pdfft?md5=9909c813a4b5357e27083af072dec722&pid=1-s2.0-S2949711623001077-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138839666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of double-breasted spongioplasty as additional tissue coverage in tubularized incised plate urethroplasty","authors":"Chandni,&nbsp;Muhammad Amjad Chaudhary,&nbsp;Asad Iqbal","doi":"10.1016/j.yjpso.2023.100111","DOIUrl":"https://doi.org/10.1016/j.yjpso.2023.100111","url":null,"abstract":"<div><h3>Background</h3><p>Modern hypospadiology is constantly developing new ideas to improve functional outcomes. Tubularized incised plate urethroplasty (TIPU) with neourethral covering by vascularized tissue (dartos flap, corpus spongiosum) is presently the most common procedure performed. Aim of this study was to evaluate the effectiveness of double-breasted spongioplasty (DBS) as additional tissue coverage in TIPU by comparing it with TIPU without spongioplasty.</p></div><div><h3>Methods</h3><p>We conducted a prospective comparative study from September 2022 to October 2023 on 120 midshaft and distal hypospadias cases aged 1 to 12 years. Group A (<em>n</em> = 60) underwent TIPU without spongioplasty; Group B (<em>n</em> = 60) underwent TIPU with DBS. Pre-operative patient parameters were categorized according to Glans-Meatus-Shaft (GMS) Score. Follow-up was 4 months to one year. Complications like urethrocutaneous fistula (UCF) and meatal stenosis (MS) were recorded. Functional outcomes were assessed using Hypospadias objective scoring evaluation (HOSE).</p></div><div><h3>Results</h3><p>Average age was 5.68 ± 2.26 in group A and 6.40 ± 2.10 in group B. Group A had mean GMS 5.32 ± 1.09; Group B had 5.45 ± 1.12 (<em>p</em> = 0.49). In group A, 4 (6.66 %) had MS, 5 (8.33 %) had UCF; in group B, 5 (8.33 %) had MS, 2 (3.33 %) had UCF (<em>p</em> &gt; 0.05). Dorsal plication for ventral curvature was avoided in 7 patients after DBS. Surgeon evaluated mean HOSE was 14.73 ± 1.87 in Group A and 15.40 ± 1.26 in B (<em>p</em> = 0.02); in group A, 83.33 % while in group B 95 % cases had acceptable HOSE (≥14) (<em>p</em> = 0.04).</p></div><div><h3>Conclusion</h3><p>Double-breasted spongioplasty in TIPU has better functional outcomes when compared with TIPU without spongioplasty and may correct ventral curvature of mild to moderate severity.</p></div><div><h3>Level of evidence</h3><p>LEVEL II.</p></div>","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"5 ","pages":"Article 100111"},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949711623001089/pdfft?md5=48b6597d77eff318881a82b3a5b36748&pid=1-s2.0-S2949711623001089-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138656337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}