Journal of Clinical Gerontology and Geriatrics最新文献

{"title":"Dehydroepiandrosterone sulfate level and knee osteoarthritis in older adults: preliminary data for the possible link","authors":"D. Rasheedy, M. Refaee, Ghada Farag, Samia Abdelrehem, S. Pessar","doi":"10.24816/JCGG.2017.V8I1.04","DOIUrl":"https://doi.org/10.24816/JCGG.2017.V8I1.04","url":null,"abstract":"Background: Dehydroepiandrosterone (DHEA) is believed to be protective against articular cartilage injury and it is widely used as one of the natural remedies for inflammatory and degenerative arthritis. Yet, information about the association between DHEA level and knee OA is lacking. Objectives: To explore the link between serum dehydroepiandrosterone sulfate (DHEAs) levels and knee OA among elderly patients. Methods: A case control study was conducted on 80 elderly subjects (40 males, 40 females) aged 60 years and older attending the outpatient clinics in Ain Shams University Hospital. Participants underwent a standard clinical examination of the knee, assessment of physical difficulty and pain severity using WOMAC OA index. Weight-bearing anteroposterior radiographs of the knees in the semi-flexed position were performed. Serum levels of DHEAs were examined. Results: The serum level of DHEAs in males with knee OA was 0.29 ± 0.17 μg/mL compared to those without knee OA 0.59 ± 0.51 μg/mL (p=0.006), small but significant difference existed between the serum level of DHEAs in females with knee OA 0.25 ± 0.11 μg/mL compared to those without knee OA 0.39 ± 0.26 μg/mL (p=0.044*). Additionally, the serum DHEAs level negatively correlated with the severity of knee OA in both sexes. Conclusions: There was a sex difference in serum DHEAs level and occurrence of knee OA. Lower levels of DHEAs were reported in elderly with knee OA and the serum DHEAs level negatively correlated with the severity of knee OA.","PeriodicalId":100764,"journal":{"name":"Journal of Clinical Gerontology and Geriatrics","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85288290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Very elderly-onset systemic lupus erythematosus presented with mixed-type autoimmune hemolytic anemia","authors":"T. Kanie, T. Higuchi, Ryosuke Koyamada, M. Suda, Sadamu Okada","doi":"10.24816/jcgg.2017.v8i1.07","DOIUrl":"https://doi.org/10.24816/jcgg.2017.v8i1.07","url":null,"abstract":"An 86-year-old Japanese woman presented with severe anemia and was diagnosed as mixed-type autoimmune hemolytic anemia (AIHA). Subsequently, although she did not show typical manifestations of systemic lupus erythematosus (SLE), she was diagnosed as SLE complicated with Sjögren's syndrome and Greves’ disease. While AIHA occurs in 5-10% of SLE patients and SLE is the most common underlying condition of mixed-type AIHA, complication of mixed-type AIHA among SLE patients has not been studied yet. SLE mainly affects women of child-bearing age and is seldom diagnosed in elderlies and the present case is the oldest SLE patient presented with mixed type-AIHA reported so far in the literature, indicating that mixed-type AIHA may complicate in elderly SLE patients and thorough evaluation of the possibility of the complication is justified. She also exemplifies the notion that elderly SLE patients often present with manifestations different from those in younger patients.","PeriodicalId":100764,"journal":{"name":"Journal of Clinical Gerontology and Geriatrics","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90693495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Organ Toxicity from Benzene Exposure among Elderly Subjects after a Flaring Disaster at the BP Refinery Plant in Texas City","authors":"M. D’Andrea, Kesava Reddy","doi":"10.24816/JCGG.2017.V8I1.05","DOIUrl":"https://doi.org/10.24816/JCGG.2017.V8I1.05","url":null,"abstract":"Objectives: To evaluate the health risks associated with benzene exposure in elderly subjects following a flaring disaster at the BP refinery in Texas City, Texas. Methods: Elderly subjects aged 60 years and older who had been exposed and unexposed to benzene were included. We reviewed medical charts and compared measures of white blood cells (WBC), platelets, hemoglobin, hematocrit, blood urea nitrogen (BUN), creatinine, alkaline phosphatase (ALP), aspartate amino transferase (AST), and alanine amino transferase (ALT) in exposed and unexposed elderly subjects. Results: Records from 294 elderly subjects (benzene exposed, n=216 and unexposed, n=78) were reviewed. Benzene exposed subjects had significantly higher levels of WBC (X 103 per μL) (7.7±1.9 versus 6.3±1.5, P=0.0000) and platelet (X 103 per μL) counts (256.8 ± 51.6 versus 237.9 ± 41.9, P=0.0104) compared with the unexposed subjects. Serum creatinine levels (mg/dL) were also significantly increased in the exposed group compared with the unexposed group (1.1 ± 0.4 versus 0.9±0.2, P=0.000). Serum levels of ALP (IU/L) were significantly elevated in the exposed subjects compared with the unexposed subjects (87.5 ± 23.6 versus 72.5 ± 17.8, P=0.000). Similarly, benzene exposed subjects had significantly higher levels of AST (24.8 ± 6.2 versus 19.2 ± 5.1, IU/L, P=0.000) and ALT (24.2 ± 8.6 versus 19.1 ± 4.8, IU/L, P=0.000) compared with those unexposed to benzene. Conclusions: Benzene exposure resulted in significant alterations in hematological and hepatic profiles among elderly subjects.","PeriodicalId":100764,"journal":{"name":"Journal of Clinical Gerontology and Geriatrics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89580639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Behavior management: It's impact on dementia patients and caregivers","authors":"S. Chand","doi":"10.24816/JCGG.2017.V8I1.01","DOIUrl":"https://doi.org/10.24816/JCGG.2017.V8I1.01","url":null,"abstract":"Behavioral and psychological symptoms of dementia (BPSD) lead to functional impairment in patients with dementia and caregiver distress. Non-pharmacological treatments of BPSD have gained increasing attention since the use of pharmacological methods has been found to be associated with negative consequences and risks. Behavioral management of BPSD is one of the non-pharmacological treatment approaches that has been utilized in psychosocial treatment programs. Behavioral strategies have also been used in the treatment of caregiver distress and depression. This paper is based on a comprehensive search of literature in PubMed/MEDLINE and Scopus. It reviews the literature to evaluate the efficacy and utility of behavior management in helping with reduction of problem behaviors along with psychological distress in caregivers of patients with dementia. Evidence indicates that despite limitations in the studies, incorporation of behavioral management strategies into the care of patients with dementia is beneficial to caregivers as well as dementia patients.","PeriodicalId":100764,"journal":{"name":"Journal of Clinical Gerontology and Geriatrics","volume":"63 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83784737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving advance care planning in patients with dementia: The effect of training nurses to engage in acp-related conversations","authors":"M. Wils, J. Verbakel, J. Lisaerde","doi":"10.24816/JCGG.2017.V8I1.03","DOIUrl":"https://doi.org/10.24816/JCGG.2017.V8I1.03","url":null,"abstract":"© 2017, Asia Pacific League of Clinical Gerontology & Geriatrics. Background: Advance care planning consists of an individual approach to anticipate the decisions on treatment during the course of illness and at the end of life. In a nursing home setting there is a pressing need for advance care planning, especially for residents with dementia. Timely discussion of the treatment goals may help to increases the resident’s autonomy and the quality of life and care. Objectives: The aim of the study is to assess the effect of an education program for nurses on the registration of care goals in a nursing home with a population of elderly residents suffering from dementia. Another objective was to explore the views of nursing home staff on advance care planning in patients with dementia. Methods: This quantitative study is a pre-and post-intervention evaluation in a nursing home in Flanders, Belgium, providing care for a population of 124 residents diagnosed with dementia. The intervention consisted of a 12-month program for nursing staff (n=13) including training in theoretical and communication skills. This group was asked to complete a structured 10-item-questionnaire (type Likert) at 0 and 12 months between January 2011 and January 2012 exploring their views on facilitating and obstructing factors concerning the implementation of ACP. At the same time a pre-and post-measurement of all ACP-related registrations, based on a novel care goals model in the electronic medical record was done. Results: The intervention included all 124 residents diagnosed with dementia. 13 members of the nursing staff participated in the training and completed the questionnaire at point 0 and 12 months. At 12 months we noticed a significant increase in the number of interviews regarding ACP held with the residents, and also a significant increase in the number of care goals documented. We identified several facilitating factors and barriers for the ACP process. Furthermore we saw significant changes in caregiver’s views on ACP at the end of the intervention period. Conclusions: Prior to the intervention the members of the nursing staff presented some resistance towards the implementation of ACP, supported the ACP process afterwards. ACP was said to help raise the dignity and autonomy of the residents, and was especially useful in improving clarity for medical decision making. The number of successfully recorded information on ACP was increased significantly. Special attention should be given to the barriers that obstruct the implementation of ACP in the nursing home setting.","PeriodicalId":100764,"journal":{"name":"Journal of Clinical Gerontology and Geriatrics","volume":"17 1","pages":"17-20"},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86450700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of socio-economic and psychosocial factors on food insecurity and nutritional status of older adults in felda settlement in malaysia","authors":"Rohida Saleh Hudin, S. Shahar, Norhayati Ibrahim, Hanis Mastura Yahaya","doi":"10.24816/JCGG.2017.V8I1.06","DOIUrl":"https://doi.org/10.24816/JCGG.2017.V8I1.06","url":null,"abstract":"Background/Purpose: Older adults are at high risk of food insecurity and malnutrition. However, the magnitude of food insecurity and malnutrition and their associations with socio-economic and psychosocial factors among older adults especially in rural areas of Malaysia are yet to be discovered. Therefore, this study aimed to determine the association between socio-economic and psychosocial factors with food insecurity and among older adults people in a rural area of Malaysia, i.e. an agricultural settlement under the Felda Land Development Authority (FELDA).","PeriodicalId":100764,"journal":{"name":"Journal of Clinical Gerontology and Geriatrics","volume":"29 1","pages":"35-40"},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82649946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors of trospium treatment compliance among unemployed older persons","authors":"K. Kosilov, S. Loparev, I. Kuzina, O. Shakirova, N. Zhuravskaya, Alexandra Lobodenko","doi":"10.1016/J.JCGG.2016.04.003","DOIUrl":"https://doi.org/10.1016/J.JCGG.2016.04.003","url":null,"abstract":"","PeriodicalId":100764,"journal":{"name":"Journal of Clinical Gerontology and Geriatrics","volume":"30 1","pages":"124-130"},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87979058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology of vancomycin-resistant enterococci in postacute care facility and predictors of clearance: A 5-year retrospective cohort study","authors":"D. Miu, S. Ling, C. Tse","doi":"10.1016/J.JCGG.2015.11.002","DOIUrl":"https://doi.org/10.1016/J.JCGG.2015.11.002","url":null,"abstract":"","PeriodicalId":100764,"journal":{"name":"Journal of Clinical Gerontology and Geriatrics","volume":"100 1","pages":"153-157"},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90065844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Concomitant use of psychotropics and donepezil in Japanese patients with dementia: Pooled postmarketing surveillance data analysis","authors":"Kasumi Daidoji MSc ,&nbsp;Yukinori Sakata MSc ,&nbsp;Kenta Sumitomo MSc ,&nbsp;Mika Ishii MSc ,&nbsp;Tetsumi Toyoda BEng ,&nbsp;Mika Kawaguchi MSc","doi":"10.1016/j.jcgg.2016.05.005","DOIUrl":"https://doi.org/10.1016/j.jcgg.2016.05.005","url":null,"abstract":"<div><h3>Background/Purpose</h3><p>Psychotropics are administered to control behavioral and psychological symptoms of dementia. In 2005, the Food and Drug Administration (FDA) issued alerts regarding their use as antipsychotics in elderly patients with dementia-related psychosis. Guidelines on psychotropic use were also recently established in Japan; however, few studies have reported on the actual usage of psychotropics among patients with dementia in clinical settings. The aim of this study was to estimate the frequency of psychotropic use in patients with Alzheimer's disease receiving donepezil.</p></div><div><h3>Methods</h3><p>Data from six prospective, postmarketing studies of donepezil in patients with Alzheimer's disease conducted between 1999 and 2011 were pooled for analysis. Patient and clinical characteristics at baseline were analyzed descriptively. The proportion of psychotropics used concomitantly with donepezil was calculated for all patients and for patients divided into types of psychotropics used, sex, age, and study time period. As for the study time period, studies were divided into two groups: the period before the FDA alert was issued (1994–2004) and the period after (2005–2011).</p></div><div><h3>Results</h3><p>A total of 14,726 patients were analyzed (67.0% women, aged 79.3 ± 7.2 years). The overall proportion of psychotropic use was 24.2%. The number of psychotropics used was one in 8.2% of patients, two in 8.1%, and ≥ 3 in 5.5%. The types of psychotropics used were as follows: typical antipsychotics, 7.8%; atypical antipsychotics, 4.4%; antidepressants, 5.7%; anxiolytics, 6.4%; and hypnotics, 11.0% (% does not sum up to 24.2% due to multiple use). With regards to the time periods, in studies conducted between 1999 and 2004 versus those between 2005 and 2011, the proportions were 31.7% and 21.3%, respectively.</p></div><div><h3>Conclusion</h3><p>Psychotropic use was seen in a quarter of patients with dementia receiving donepezil in Japan. Additionally, the overall proportion decreased after the alert issued by the FDA in 2005.</p></div>","PeriodicalId":100764,"journal":{"name":"Journal of Clinical Gerontology and Geriatrics","volume":"7 4","pages":"Pages 131-135"},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jcgg.2016.05.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72244935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"General Informatiom","authors":"","doi":"10.1016/S2210-8335(16)30064-8","DOIUrl":"https://doi.org/10.1016/S2210-8335(16)30064-8","url":null,"abstract":"","PeriodicalId":100764,"journal":{"name":"Journal of Clinical Gerontology and Geriatrics","volume":"7 4","pages":"Page iii"},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S2210-8335(16)30064-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72245070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}