Safoura Seifi , Tahere Padeganeh , Syed Razie Rezaee , Ali Bijani
{"title":"Immunohistochemical evaluation of inducible nitric oxide synthase (iNOS) expression in the dental follicle, follicular cyst, and calcifying cystic odontogenic tumor","authors":"Safoura Seifi , Tahere Padeganeh , Syed Razie Rezaee , Ali Bijani","doi":"10.1016/j.ijdsr.2015.11.007","DOIUrl":"10.1016/j.ijdsr.2015.11.007","url":null,"abstract":"<div><h3>Objective</h3><p><span><span>The calcifying cystic odontogenic tumor (CCOT) is a benign cystic neoplasm<span> with a variety of histopathological and clinical features in comparison with the follicular cyst. </span></span>iNOS<span> is an enzyme that produces free radicals and is a mediator regulator of the inflammatory response. It has been implicated in tumorigenesis as well. The aim of this study was to compare iNOS expression in the </span></span>dental follicle and two odontogenic lesions with different aggressive behaviors.</p></div><div><h3>Methods</h3><p>In this cross-sectional study, 44 paraffin blocks were selected from the dental follicle, follicular cyst, and CCOT, and immunohistochemical staining was done by iNOS. The percentage and intensity of staining (total score) were calculated in the cytoplasm of the epithelial cells.</p></div><div><h3>Results</h3><p>The highest total score of iNOS staining was found in the cytoplasm of the epithelial cells of CCOT when compared to the follicular cyst and dental follicle (<em>p</em> <!-->=<!--> <!-->0.000). There was a significant difference in the final score between the follicular cyst and dental follicle (<em>p</em> <!-->=<!--> <!-->0.001).</p></div><div><h3>Discussion</h3><p>The overexpression of iNOS in the CCOTs plays a role in its pathogenesis and iNOS, because of producing free radicals and damaging the oral tissue, may contribute to more aggressive behaviors of CCOT.</p></div>","PeriodicalId":100695,"journal":{"name":"International Journal of Dental Science and Research","volume":"3 1","pages":"Pages 9-14"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijdsr.2015.11.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115838898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gargi S. Sarode , Sachin C. Sarode , Meena Kulkarni , Swarada Karmarkar , Shankargouda Patil
{"title":"Role of bioimpedance in cancer detection: A brief review","authors":"Gargi S. Sarode , Sachin C. Sarode , Meena Kulkarni , Swarada Karmarkar , Shankargouda Patil","doi":"10.1016/j.ijdsr.2015.11.003","DOIUrl":"10.1016/j.ijdsr.2015.11.003","url":null,"abstract":"<div><p><span>Bioimpedance is a term, which describes the response of living organisms to an externally applied current. It is a measure of opposition to the flow of the applied current through tissues. The measurement of bioimpedance of a living organism is non-invasive method for assessing its composition. A bioimpedance signal can be used for characterizing the tissue. The electrical properties of tissue vary with different applied frequencies. Bioimpedance is a well-established method in detecting breast cancer, cervical cancer, prostate cancer<span>, etc. The studies showed that there are significant differences in bioimpedance between normal tissues and cancerous tissue. With this view in mind narrative review article is written to deliberate role of bioimpedance in various malignancies of the body. We also discussed studies done on </span></span>oral squamous cell carcinoma (OSCC) and realized the need for more studies especially on oral potentially malignant disorders and OSCC together. The role of bioimpedance in malignancies was searched in databases such as PUBMED and SCOPUS with no restriction to the date of publication. Articles published in English medical literature on OSCC have been selected for discussion.</p></div>","PeriodicalId":100695,"journal":{"name":"International Journal of Dental Science and Research","volume":"3 1","pages":"Pages 15-21"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijdsr.2015.11.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125488937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gorlin-Goltz syndrome: A rare case report","authors":"Mubeen Khan , K.R. Vijayalakshmi , Preeti Rajguru","doi":"10.1016/j.ijdsr.2015.11.009","DOIUrl":"10.1016/j.ijdsr.2015.11.009","url":null,"abstract":"<div><p><span>Gorlin-Goltz syndrome (GGS) is a rare genetic disease that is transmitted as an autosomal-dominant trait showing high level of penetrance and varying expressivity affecting multiple systems of the body. Characteristic clinical manifestations include the presence of multiple </span>basal cell carcinomas<span>, odontogenic keratocysts of the jaws, palmar/plantar pits and calcification of falx cerebri. Early diagnosis of GGS is of great importance due to susceptibility of affected individuals to multiple neoplasms of skin and brain (medulloblastoma) in an early age; life expectancy in GGS is not significantly altered, but morbidity from complications can be substantial. Dentist plays a crucial role in early diagnosis, which prevents recurrence and provides better survival rates from the existent diseases.</span></p><p>We are reporting a rare case of GGS in a 14-year-old girl who visited our institution with characteristic clinical, radiological and histological features.</p></div>","PeriodicalId":100695,"journal":{"name":"International Journal of Dental Science and Research","volume":"3 1","pages":"Pages 26-30"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijdsr.2015.11.009","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132704138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sublingual epidermoid cyst mimicking as plunging ranula – A case report","authors":"Zeeshan Qamar , Kashif Ikram , Tayyaba Fatima","doi":"10.1016/j.ijdsr.2015.11.004","DOIUrl":"10.1016/j.ijdsr.2015.11.004","url":null,"abstract":"<div><p><span>Among all the epidermoid cysts originating throughout the body, 7% occurs in the head and neck region, with 1.6% intra-orally. Intra-orally, it is mainly located in the submandibular, sublingual and submental region as a benign, painless lesion. This leads to symptoms such as </span>dysphagia<span>, dyspnoea and have a malignant transformation<span> potential as well. Treatment<span> of choice is surgical excision. This is a case report of epidermoid cyst diagnosed clinically as plunging ranula.</span></span></span></p></div>","PeriodicalId":100695,"journal":{"name":"International Journal of Dental Science and Research","volume":"3 1","pages":"Pages 22-25"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijdsr.2015.11.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127245526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence of palatally impacted canines","authors":"Telmo Moreira, Ana Braga, Afonso Ferreira","doi":"10.1016/j.ijdsr.2015.11.006","DOIUrl":"10.1016/j.ijdsr.2015.11.006","url":null,"abstract":"<div><h3>Background</h3><p><span>Palatally impacted canines (PICs) are among dental anomalies with different prevalence in each region. This study was designed to investigate the prevalence of palatally impacted cuspids in Portuguese population, and to evaluate the possible relationships between PIC, gender, </span>malocclusions, facial biotype, and morphological and occlusion features.</p></div><div><h3>Methods</h3><p>A descriptive, retrospective, and cross-sectional study was conducted. The sample consisted of 1333 patients (581 males and 752 females), 12–63 years old evaluated in a period between September 2003 and December 2010. The clinical records were studied for evidence of one or both canines palatally impacted. Collected data were analyzed using chi-square tests (decision rule was <em>α</em> <!-->=<!--> <!-->0.05).</p></div><div><h3>Results</h3><p>The most frequent PIC was right cuspid. Females showed higher number of PIC. The prevalence of PICs in females was found approximately 5.2%.</p></div><div><h3>Conclusions</h3><p>The prevalence of PICs in Portuguese population was 4.5% (with 95% confidence interval: [3.5%, 5.8%]). The frequency is greater of impacted cuspids in females than in males.</p></div>","PeriodicalId":100695,"journal":{"name":"International Journal of Dental Science and Research","volume":"3 1","pages":"Pages 2-8"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijdsr.2015.11.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124289275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Charge for consultations/counselling?","authors":"Ankita Arora, Krishna Arora","doi":"10.1016/j.ijdsr.2015.10.002","DOIUrl":"10.1016/j.ijdsr.2015.10.002","url":null,"abstract":"","PeriodicalId":100695,"journal":{"name":"International Journal of Dental Science and Research","volume":"2 2","pages":"Page 89"},"PeriodicalIF":0.0,"publicationDate":"2015-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijdsr.2015.10.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115577451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A new clinical approach for rehabilitation of crown fracture by fragment reattachment – A case report","authors":"Neha Sharma , Manmohan Bramta","doi":"10.1016/j.ijdsr.2015.04.003","DOIUrl":"10.1016/j.ijdsr.2015.04.003","url":null,"abstract":"<div><p><span><span>Maxillary incisors and specifically their crowns are the most common teeth involved in dental trauma because of their anterior positioning in </span>oral cavity<span> and protrusive eruptive pattern. Traumatized anterior teeth<span><span> require quick functional and esthetic repair. Various treatment modalities have been suggested for complicated crown fractures, however reattachment of the fractured fragment is said to be beneficial in many ways. A 16 year old female patient reported with </span>sports injury to both of her </span></span></span>maxillary central incisors<span> and left maxillary lateral incisor. In this case, of complicated crown fracture we used one alternate technique where the fractured fragment was attached onto a glass fiber post (intra-canal anchorage) and then the unit was repositioned in the post space prepared in the root canals using resin luting cement. Reattachment was possible in this case because the fractured fragments were intact and we could achieve a good approximation as the crown and post were inserted as a single unit and thorough curing of the composite was achieved as it was cured extra orally. The whole process was less time consuming and since most of the work was done extra orally maintenance of isolation needed very less time.</span></p></div>","PeriodicalId":100695,"journal":{"name":"International Journal of Dental Science and Research","volume":"2 2","pages":"Pages 84-88"},"PeriodicalIF":0.0,"publicationDate":"2015-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijdsr.2015.04.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115725145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between periodontitis, prematurity, low birth weight, and CRP levels – A case–control study","authors":"P.R. Ganesh","doi":"10.1016/j.ijdsr.2015.11.005","DOIUrl":"10.1016/j.ijdsr.2015.11.005","url":null,"abstract":"<div><h3>Background</h3><p>To analyze the role of periodontal infections in pre-term low birth weight deliveries and to prevent prematurity.</p></div><div><h3>Aim</h3><p>To evaluate the association between maternal periodontal disease and adverse pregnancy outcome and to assess the CRP levels as the possible mediator.</p></div><div><h3>Methods</h3><p>A retrospective case–control study conducted during a one year period from amongst the post-natal women who delivered an infant before 37 weeks gestation (Study group) and after 37 weeks gestation (Control group) selected on a 1:1 ratio. All the study participants underwent an intra-oral examination by a qualified periodontologist within 72<!--> <span>h postpartum to measure probing depth and CAL. Also, 5</span> <!-->ml of blood was drawn for estimation of C-reactive protein (CRP) levels in both groups.</p></div><div><h3>Results</h3><p><span>Analysis of maternal periodontal disease in both groups showed a significantly greater number of mothers with generalized chronic periodontitis<span> in the case group than in the control group and that the adjusted Odds Ratio for the association between periodontitis<span> and preterm labor was 4.78. Also, the gestational age at delivery was found to be inversely proportional to the degree of periodontitis as those mothers with severe periodontitis delivered the most preterm infants with GA of 30.5 weeks. It was also seen that the mean birth weight also decreased with increasing severity of periodontitis with a mean birth weight of 1.2</span></span></span> <!-->kg in severe periodontitis patients. The CRP levels were higher in the cases than in the controls and were found to increase with increasing severity of periodontitis.</p></div><div><h3>Conclusion</h3><p>The study concludes that there is a significant association between periodontitis and preterm labor and a significant correlation between increased CRP levels, increasing severity of periodontitis and prematurity. As periodontitis is a treatable disease, prematurity can be prevented with early diagnosis.</p></div>","PeriodicalId":100695,"journal":{"name":"International Journal of Dental Science and Research","volume":"2 2","pages":"Pages 55-63"},"PeriodicalIF":0.0,"publicationDate":"2015-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijdsr.2015.11.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121729660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of glass carbomer sealant and a moisture tolerant resin sealant – A comparative study","authors":"Priya Subramaniam , Shurti Jayasurya , K.L. Girish Babu","doi":"10.1016/j.ijdsr.2015.05.001","DOIUrl":"10.1016/j.ijdsr.2015.05.001","url":null,"abstract":"<div><h3>Introduction</h3><p><span>Fissure sealants have been widely used for more than four decades in preventing dental caries. Advances in technology have led to the development of moisture tolerant sealants. They are available as resin based and </span>glass ionomer based. There is a paucity of studies on the effectiveness of moisture tolerant sealant materials in clinical conditions. AIM: The aim of the present study was to evaluate and compare the retention and caries incidence with use of the two newly introduced moisture tolerant pit and fissure sealants.</p></div><div><h3>Materials and methods</h3><p>One hundred and eight children formed the study group. The glass carbomer<span> sealant and Embrace WetBond sealant were two moisture tolerant sealants used. The sealant was applied on the occlusal surface of the teeth following the manufacturer's instructions. Children were recalled for assessment of sealant retention and the teeth were examined for dental caries on the occlusal surface using mouth mirror and blunt probe following 1, 3,6,12,18 and 24 months. Sealants were assessed according to a modified version of the CCC sealants evaluation system described by Deery et al. RESULTS: At 18 and 24 months, both GC and EBW showed similar pattern of sealant retention At 24 months, enamel caries was observed in 3 teeth sealed with EBW as compared to only 1 tooth sealed with GC.</span></p></div><div><h3>Conclusions</h3><p>There was no significant difference between the retention of glass carbomer sealant and Embrace WetBond sealant, at the end of 2 years. There was no significant difference in the caries incidence between both these sealants.</p></div>","PeriodicalId":100695,"journal":{"name":"International Journal of Dental Science and Research","volume":"2 2","pages":"Pages 41-48"},"PeriodicalIF":0.0,"publicationDate":"2015-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijdsr.2015.05.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125014364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hala A. Bahgat , Emad AlShwaimi , Abeer E. El-Embaby
{"title":"Evaluation of the bonding ability of a nano-structured adhesive system","authors":"Hala A. Bahgat , Emad AlShwaimi , Abeer E. El-Embaby","doi":"10.1016/j.ijdsr.2015.10.001","DOIUrl":"10.1016/j.ijdsr.2015.10.001","url":null,"abstract":"<div><p>The most significant advantage of self-etching primers is to simplify bonding procedures and reduce technique sensitivity.</p></div><div><h3>Aims</h3><p>The aim of this study is to evaluate the shear bond strength (SBS) of self-etch primers, such as polyhedral oligomeric silsesquioxanes (POSS) and silica filled adhesive systems and to assess the nano-leakage (NL) at the resin–dentin interface with field-emission scanning electron microscope (FE-SEM) before and after aging.</p></div><div><h3>Methods</h3><p>One light cured nano-hybrid composite resin and two self-etch primer adhesive systems (Nano-bond and AdheSE) have been used. Sixty extracted sound human molars were prepared for SBS: two self-etch primer adhesive systems (Nano-bond and AdheSE) have been used for bonding a light cured nano-hybrid composite resin. The test was performed at a universal testing machine and twelve were prepared for evaluation of NL at the interface with FE-SEM before and after aging. Data were statistically analyzed using multiple ANOVA and post hoc Scheffe test (<em>p</em> <!--><<!--> <!-->0.05).</p></div><div><h3>Results</h3><p>Nano-bond showed higher significant SBS values compared to AdheSE groups in the testing groups. Mean while a significant reduction in SBS was observed in each of the tested adhesive systems, after aging, where the highest was recorded by the control, followed by the thermal cycling and finally by the thermal cycling and water storage. The representative micrographs revealed more pronounced NL pattern in the specimens of AdheSE groups when compared to those of Nano-bond.</p></div><div><h3>Conclusions</h3><p>Within the limitation of this laboratory study, the following conclusions could be drawn:</p><ul><li><span>1.</span><span><p>The incorporation of the POSS molecules in the dentin adhesive improves its bonding strength.</p></span></li><li><span>2.</span><span><p>Chemical formulation of the dental adhesive influences its bonding efficiency.</p></span></li><li><span>3.</span><span><p>Nano-structured adhesive system shows better resistance to nano-leakage.</p></span></li></ul></div>","PeriodicalId":100695,"journal":{"name":"International Journal of Dental Science and Research","volume":"2 2","pages":"Pages 34-40"},"PeriodicalIF":0.0,"publicationDate":"2015-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijdsr.2015.10.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120909233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}