Food Safety and Health最新文献_第3页

Bioactive peptides from livestock milk and casein as alternative functional foods 畜禽奶中的生物活性肽和酪蛋白作为功能性食品的替代品

Food Safety and Health Pub Date : 2024-11-23 DOI: 10.1002/fsh3.12083

Eng Huan Hau, Ling Li, Siau Hui Mah

引用次数: 0

An investigation into the transcription factors and regulatory mechanisms of Aspergillus 曲霉转录因子及其调控机制的研究

Food Safety and Health Pub Date : 2024-11-18 DOI: 10.1002/fsh3.12080

Yuxin Qin, Huawei Yu, Jun Tian

引用次数: 0

Oral administration of tannic acid attenuates dyslipidemia, hyperglycemia, and oxidative stress in high-fat and fructose diet-induced obesity in rats 口服单宁酸可减轻高脂肪和果糖饮食引起的肥胖大鼠的血脂异常、高血糖和氧化应激

Food Safety and Health Pub Date : 2024-11-11 DOI: 10.1002/fsh3.12081

Emmanuel Ejiofor, Ernest Agwamba, Chima Egedigwe-Ekeleme, Paul Nweje-Anyalowu, Hitler Louis, Innocent Abalake, Francis Imeh, Bliss Harold, Deborah Azuh, Maureen Ejiofor, Christian Okoro, Joan Ejiofor, Chidinma Ekwegbalu, Laurene Ekwugha

{"title":"Oral administration of tannic acid attenuates dyslipidemia, hyperglycemia, and oxidative stress in high-fat and fructose diet-induced obesity in rats","authors":"Emmanuel Ejiofor, Ernest Agwamba, Chima Egedigwe-Ekeleme, Paul Nweje-Anyalowu, Hitler Louis, Innocent Abalake, Francis Imeh, Bliss Harold, Deborah Azuh, Maureen Ejiofor, Christian Okoro, Joan Ejiofor, Chidinma Ekwegbalu, Laurene Ekwugha","doi":"10.1002/fsh3.12081","DOIUrl":"https://doi.org/10.1002/fsh3.12081","url":null,"abstract":"<p>Obesity and diabetes are considered life-threatening conditions, characterized by increased oxidative stress, insulin resistance, hepatotoxicity, hyperglycemia, and hypercholesterolemia. Therefore, we studied the effects of tannic acid in a high-fat and fructose-diet-induced rat model of obesity. Administration of tannic acid at doses of 200 and 400 mg/kg significantly reduced fasting blood glucose concentration, reversed disoriented lipid profile, decreased liver enzyme activities, and inhibited oxidative stress compared to the high-fat, high-sugar group. Histopathological examination showed preserved pancreas and liver architecture in the tannic acid-administered groups. The in vitro inhibitory activity of tannic acid against alpha-amylase, alpha-glucosidase, and pancreatic lipase showed good inhibitory potential. Molecular docking studies showed high binding affinity and more hydrogen bond interactions between tannic acid and receptor proteins (alpha-amylase, alpha-glucosidase, and pancreatic lipase) implicated in obesity and diabetes. In conclusion, tannic acid prevented the onset of oxidative stress, preserved the liver, and restored the disoriented lipid profile in high-fat and fructose diet-induced obesity in rats.</p>","PeriodicalId":100546,"journal":{"name":"Food Safety and Health","volume":"3 2","pages":"250-263"},"PeriodicalIF":0.0,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsh3.12081","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143849116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Duckweed: Growth factor and applications in nonfood, food, and health 浮萍：生长因子及其在非食品、食品和健康领域的应用

Food Safety and Health Pub Date : 2024-11-03 DOI: 10.1002/fsh3.12078

Eng Huan Hau, Siau Hui Mah

{"title":"Duckweed: Growth factor and applications in nonfood, food, and health","authors":"Eng Huan Hau, Siau Hui Mah","doi":"10.1002/fsh3.12078","DOIUrl":"https://doi.org/10.1002/fsh3.12078","url":null,"abstract":"<p>Duckweeds are aquatic plants and mainly constitute of five genera, <i>Lemna, Spirodela, Wolffia</i>, <i>Wolffiella,</i> and <i>Landoltia.</i> These are the smallest plants yet having a rapid growth rate. Hence, duckweeds are sustainable food sources for humans and animals, as well as sustainable feedstocks for biochemical production. Previously, duckweeds were discovered for their vital role in water purification by metabolizing chemicals and waste. However, many recent studies have discovered that duckweeds have a high amount of nutrients, which makes them a great substitute in human diets and animal feed. Their nutrient composition and growth rate are greatly affected by environmental factors. Hence, this review summarizes the characteristics of duckweeds, growth rate factors, and their applications in nonfood, food, and health. Duckweeds could improve health due to their large amounts of macro- and micronutrients. Future studies on the safety measures and duckweed culture are strongly recommended to safeguard the quality of the plants. Besides that, duckweeds have great potential to be used as heavy metals or contaminants absorbent, as well as a sustainable feedstock for biofuel production.</p>","PeriodicalId":100546,"journal":{"name":"Food Safety and Health","volume":"3 2","pages":"144-154"},"PeriodicalIF":0.0,"publicationDate":"2024-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsh3.12078","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143849108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unveil the molecular recognition mechanisms of triazine haptens and monoclonal antibodies: Establishing ic-ELISA methods for triazine herbicide analysis in tea 揭示三嗪半抗原和单克隆抗体的分子识别机制：建立茶中三嗪类除草剂的ic-ELISA分析方法

Food Safety and Health Pub Date : 2024-10-30 DOI: 10.1002/fsh3.12069

Lingyuan Xu, A. M. Abd El-Aty, Peipei Li, Jia Li, Jing Zhao, Xingmei Lei, Song Gao, Yun Zhao, Yongxin She, Fen Jin, Jing Wang, Bruce D. Hammock, Maojun Jin

{"title":"Unveil the molecular recognition mechanisms of triazine haptens and monoclonal antibodies: Establishing ic-ELISA methods for triazine herbicide analysis in tea","authors":"Lingyuan Xu, A. M. Abd El-Aty, Peipei Li, Jia Li, Jing Zhao, Xingmei Lei, Song Gao, Yun Zhao, Yongxin She, Fen Jin, Jing Wang, Bruce D. Hammock, Maojun Jin","doi":"10.1002/fsh3.12069","DOIUrl":"https://doi.org/10.1002/fsh3.12069","url":null,"abstract":"<p>This study introduced two triazine haptens (with 0 or 1 carbon connecting arms at nonisopropyl positions) and developed two heterologous indirect competitive enzyme-linked immunosorbent assay (ic-ELISA) methods. The IC<sub>50</sub> values for the 17 triazine pesticides ranged from 0.84 ng/mL to 225.63 ng/mL, and the established method was applied to determine their concentrations in tea samples. This study aimed to address the current debate on the recognition mechanism of triazine haptens with shorter connecting arms. This study produced two new findings by investigating the recognition mechanism of triazine haptens and antibodies. On the one hand, the specific amino acid isoleucine (ILE-219) is crucial for isopropyl recognition. On the other hand, the selection of the connecting site of the triazine hapten has a significant effect on the specificity of the antibody, with the influence of the length of the carbon connecting arm being secondary. Our newly designed haptens show promise for diverse triazine pesticide immunoassay applications. This discovery established a foundational framework for constructing a tailored antibody library for pollutants.</p>","PeriodicalId":100546,"journal":{"name":"Food Safety and Health","volume":"3 1","pages":"61-76"},"PeriodicalIF":0.0,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsh3.12069","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143121431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring the potential mechanisms of polysaccharides against gastric ulcer: Network pharmacology analysis and molecular docking validation 探讨多糖抗胃溃疡的潜在机制：网络药理学分析和分子对接验证

Food Safety and Health Pub Date : 2024-10-28 DOI: 10.1002/fsh3.12079

Jia-Yu Huang, Qi Zou, Ming Hao, Jian-Lin Shen, Meng-Tong Zhang, Fei Li, Quan-Sheng Xu, Han-Yue Zhang, Jun Zhang, Xiao-Yin Wang

{"title":"Exploring the potential mechanisms of polysaccharides against gastric ulcer: Network pharmacology analysis and molecular docking validation","authors":"Jia-Yu Huang, Qi Zou, Ming Hao, Jian-Lin Shen, Meng-Tong Zhang, Fei Li, Quan-Sheng Xu, Han-Yue Zhang, Jun Zhang, Xiao-Yin Wang","doi":"10.1002/fsh3.12079","DOIUrl":"https://doi.org/10.1002/fsh3.12079","url":null,"abstract":"<p>Gastric ulcer is a common peptic ulcer that affects human health and life quality seriously. As anti-gastric ulcer drugs usually cause side-effects, polysaccharides may be the potential alternatives because of better effectiveness and less toxicity. Although the anti-gastric ulcer activities of polysaccharides have been widely reported, the mechanisms have not yet been well-disclosed. In this study, network pharmacology analysis was performed to explore the potential mechanisms of polysaccharides against gastric ulcer, and the results were validated by molecular docking. Results indicated that β-glucan, arabinogalactan, xylan, and arabinan were the key structures, and ABL1, AKT1, androgen receptor, epidermal growth factor receptor, v-Ha-ras Harvey rat sarcoma viral oncogene homolog, HSP90AA1, mitogen-activated protein kinase 8 (MAPK8), MAPK14, NOS2, PIK3R1, RAC1, ras homolog gene family member A, and proto-oncogene tyrosine-protein kinase Src were the core targets for polysaccharides in treating gastric ulcer. Polysaccharides have influences on 1958 GO items and 199 KEGG pathways, and their anti-gastric ulcer activities are related to MAPK, Ras, PI3K-Akt, vascular endothelial growth factor, prolactin, FoxO and Rap1 signaling pathways, etc. Molecular docking validation showed that the results of network pharmacology analysis were credible, and interactions between polysaccharide structures and core targets were observed. This study contributes to understanding the mechanisms of polysaccharides in treating gastric ulcer and provides references for future activity screening and mechanism research in anti-gastric ulcer.</p>","PeriodicalId":100546,"journal":{"name":"Food Safety and Health","volume":"3 2","pages":"232-249"},"PeriodicalIF":0.0,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsh3.12079","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143849166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of antioxidant-rich curd fortified with encapsulated beetroot (Beta vulgaris L.) peel extract powder 开发富含抗氧化剂的凝乳，其中添加了封装甜菜根（Beta vulgaris L.）果皮提取物粉末

Food Safety and Health Pub Date : 2024-10-23 DOI: 10.1002/fsh3.12075

Surabhi Pandey, Anurag Singh

{"title":"Development of antioxidant-rich curd fortified with encapsulated beetroot (Beta vulgaris L.) peel extract powder","authors":"Surabhi Pandey, Anurag Singh","doi":"10.1002/fsh3.12075","DOIUrl":"https://doi.org/10.1002/fsh3.12075","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <p>A curd with enhanced antioxidants was developed adding nanoencapsulated Beetroot Peel Extract Powder (BPEM) @ 1.0 % w/v of milk. Beetroot peel extract-based powder was produced by the spray drying technique using maltodextrin and guar gum as coating agents. The prepared samples were tested for sensory characteristics, textural properties, antioxidant content, and proximate characteristics. The results show that the sensorial characteristics of the fortified curd were improved as compared to the control one. The incorporation of nanoencapsulated BPEM resulted in a softer and more delicate texture of the fortified curd (Hardness [N]: 195 ± 10.6) as compared to control (Hardness [N]: 335 ± 3.53). The physicochemical properties of antioxidant-enhanced curd resulted in 87.4 ± 0.7% moisture, 2.2 ± 0.35% fat, 4.76 ± 0.04% protein, 14.6 ± 0.35% total solids, and 6.59 ± 0.10% carbohydrate. Furthermore, the addition of beetroot peel extract-based powder showed a higher antioxidant (76.6 ± 0.72% DPPH inhibition) and phenolic content (85.7 ± 0.25 μg Gallic acid equivalent [GAE]/mL) in the developed curd as compared to the control (54 ± 0.66% DPPH inhibition and 59.9 ± 0.75 μg GAE/mL total phenolic content).</p>\u0000 </section>\u0000 </div>","PeriodicalId":100546,"journal":{"name":"Food Safety and Health","volume":"3 2","pages":"202-216"},"PeriodicalIF":0.0,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsh3.12075","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143849048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Tapioca and Tragacanth based edible coatings on the physiological, chemical, microbial, and phytochemical quality of Tomato fruits 木薯粉和黄芪基可食性涂层对番茄果实生理、化学、微生物和植物化学品质的影响

Food Safety and Health Pub Date : 2024-10-20 DOI: 10.1002/fsh3.12077

Haya Fatima, Ammara Ainee, Tusneem Kausar, Mian Anjum Murtaza, Ashiq Hussain, Muhammad Siddique Raza, Sidrah, Barira Bibi, Amina Ayesha, Muhammad Rehan Arif, Muhammad Zia, Nida Firdous, Abdeen Elsiddig Elkhedir

{"title":"Effect of Tapioca and Tragacanth based edible coatings on the physiological, chemical, microbial, and phytochemical quality of Tomato fruits","authors":"Haya Fatima, Ammara Ainee, Tusneem Kausar, Mian Anjum Murtaza, Ashiq Hussain, Muhammad Siddique Raza,  Sidrah, Barira Bibi, Amina Ayesha, Muhammad Rehan Arif, Muhammad Zia, Nida Firdous, Abdeen Elsiddig Elkhedir","doi":"10.1002/fsh3.12077","DOIUrl":"https://doi.org/10.1002/fsh3.12077","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <p>In recent years, edible coatings have emerged as a promising solution to extend the shelf life, and maintain the quality of fruits and vegetables. The purpose of the study was the development and application of gum Tragacanth and Tapioca-based edible coatings to extend the storability and quality of tomato (<i>Solanum Lycopersicum</i> L). Different treatments were prepared with combinations of Tragacanth gum (0.5, 1, 1.5 g) and Tapioca (1, 1.5, 2 g). Parameters such as weight loss, sugars, decay percentage, pH, titratable acidity, total soluble solids, antioxidant capacity, phenolic and flavonoid contents, microbial counts, and sensory evaluation were measured during 14 days storage. Results revealed that the application of gum Tragacanth and Tapioca-based coatings significantly reduced weight loss, decay percentage, and microbial counts of treated tomatoes as compared to the control group. The coated tomatoes exhibited improved sensory features, with a slower rate of softening, during the storage. There was a significant increment in total phenolic and flavonoid contents and antioxidant capacity of coated fruits during 7 days of storage. The observed improvements in the postharvest quality attributes suggest that the gum Tragacanth and Tapioca-based edible coatings have the potential to retain and enhance the nutritional and bioactive contents and shelf life of tomato.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100546,"journal":{"name":"Food Safety and Health","volume":"3 2","pages":"217-231"},"PeriodicalIF":0.0,"publicationDate":"2024-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsh3.12077","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143849327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Guidelines for assessing the capacity of food-derived nutrients to alleviate intestinal inflammation 评估食物来源营养素减轻肠道炎症能力的指南

Food Safety and Health Pub Date : 2024-10-16 DOI: 10.1002/fsh3.12074

Jinfan Yang, Zhengqing Li, Ning Shang, Hui Zhou, Mingzhen Zhang, Guanying Li, Huafeng Kang, Xiaobin Ma, Hao Wu

{"title":"Guidelines for assessing the capacity of food-derived nutrients to alleviate intestinal inflammation","authors":"Jinfan Yang, Zhengqing Li, Ning Shang, Hui Zhou, Mingzhen Zhang, Guanying Li, Huafeng Kang, Xiaobin Ma, Hao Wu","doi":"10.1002/fsh3.12074","DOIUrl":"https://doi.org/10.1002/fsh3.12074","url":null,"abstract":"<p>Nutrients derived from food sources, such as astaxanthin, polyphenols, dietary fiber, probiotics, and short-chain fatty acids, play a crucial role in alleviating intestinal inflammation caused by sub-health conditions. These sub-health states are closely associated with a range of diseases, including colitis, gastric ulcers, and colorectal cancer. Currently, there is a lack of comprehensive guidelines that summarize quantitative and dynamic analysis methods for assessing the impact of nutrients on gastrointestinal inflammation, which limits accurate comparison and analysis of their mechanisms of action. Therefore, we summarized guidelines for evaluating the in vivo anti-inflammatory properties of food-derived nutrients. These guidelines encompass the selection of experimental models, dynamic assessment tools, long-term evaluation parameters, and exploration of inflammation-related mechanisms by disease activity index, murine endoscopic index of colitis severity (MEICS), spleen index, changes in colon length, and histology index, assessing inflammatory progression and tissue repair capabilities. By integrating these methods, researchers can conduct in-depth studies and systematic comparative analyses of the mechanisms by which food-derived nutrients alleviate intestinal inflammation. This approach will enable a more comprehensive understanding of the role of nutrition in gastrointestinal health and disease prevention.</p>","PeriodicalId":100546,"journal":{"name":"Food Safety and Health","volume":"3 1","pages":"46-60"},"PeriodicalIF":0.0,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsh3.12074","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143115491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Functional and physicochemical characterization of a novel pearl millet—Soy milk-based synbiotic beverage 一种新型珍珠粟豆浆合成饮料的功能及理化特性研究

Food Safety and Health Pub Date : 2024-10-15 DOI: 10.1002/fsh3.12076

Urvashi Srivastava, Anchal Singh, Mazia Ahmed, Unaiza Iqbal, Pinki Saini

{"title":"Functional and physicochemical characterization of a novel pearl millet—Soy milk-based synbiotic beverage","authors":"Urvashi Srivastava, Anchal Singh, Mazia Ahmed, Unaiza Iqbal, Pinki Saini","doi":"10.1002/fsh3.12076","DOIUrl":"https://doi.org/10.1002/fsh3.12076","url":null,"abstract":"<div>\u0000 <section>\u0000 <p>This study presents the physicochemical and functional characterization of a novel fermented pearl millet–soy milk-based synbiotic beverage. The synbiotic fermented pearl millet beverage was optimized at 40% pearl millet and 10.41% sugar, with hedonic score of more than eight for all the responses, through response surface methodology. The fermented synbiotic beverage, with <i>Lactiplantibacillus plantarum</i> strains exceeding 10<sup>8</sup> colony-forming units/mL, exhibited superior nutritional and physicochemical qualities when compared with the unfermented counterpart. The viability percent of lactic acid bacteria in the developed beverage was found to be significantly high (87.83%). The survivability of probiotic culture was 76.71% in simulated gastric juice and 73.87% in simulated intestinal juice after sample storage for 25 days. The result showed that millets stand out as a promising raw material for developing fermented nondairy synbiotic beverages, particularly when combined with microbial strains such as <i>L</i>. <i>plantarum</i>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100546,"journal":{"name":"Food Safety and Health","volume":"3 1","pages":"115-127"},"PeriodicalIF":0.0,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsh3.12076","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143115372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0